SKETCHY PHARM 1624m (27h4)

1. Autonomic Drugs 150m (2h30m)

1) Parasympathetic 57 mins
1.1 Cholinomimetics 16 mins
1.2 Acetylcholinesterase Inhibitors 21 mins
1.3 Muscarinic Antagonists 20 mins

2) Sympathetic 93 mins
2.1 Sympathomimetics 30 mins
2.2 Indirect Sympathomimetics 17 mins
2.3 Alpha drugs 22 mins
2.4 Beta blockers 24 mins

2. CV & Renal 250m (4h10m)

1) Heart Failure Drugs 46 mins
1.1 Digoxin, Milrinone, Nesiritide 20 mins
1.2 ACE Inhibitors, ARBs, Aliskiren 26 mins

2) Diuretics 90 mins
2.1 Acetazolamide, Mannitol 24 mins
2.2 Loop Diuretics 21 mins
2.3 Thiazides 20 mins
2.4 K+ Sparing Diuretics 25 mins

3) Antihypertensives 46 mins
3.1 Calcium channel blockers 21 mins
3.2 Primary HTN & HTN emergency 25 mins

4) Antiarrhythmics 68 mins
4.1 Class I A-C 24 mins
4.2 Class II 10 mins
4.3 Class III 12 mins
4.4 Class IV 9 mins
4.5 “Class V” 13 mins
3. Blood & Inflammation 212m (3h32m)
1) Anticoagulants & Thrombolytics 95 mins
1.1 Heparin, LMWH, fondaparinux, DTIs, Xai 30 mins
1.2 Warfarin 21 mins
1.3 Antiplatelet Agents 29 mins
1.4 Thrombolytics 15 mins

2) Dyslipidemia Drugs 59 mins

2.1 Statins 26 mins
2.2 Cholestyramine, Ezetimibe 17 mins
2.3 Fibrates, Niacin 16 mins

3) Anti-Inflammatory 58 mins
3.1 NSAIDs 34 mins
3.2 Gout Drugs 24 mins

4. Smooth Muscle 82m (1h22m)

1) Vasoactive 44 mins
1.1 Nitrates 19 mins
1.2 Triptans 9 mins
1.3 Prostaglandins, Prostacyclin, Bosentan, PDE5i 16 mins

2) Allergy & Pulmonary 38 mins

2.1 Antihistamines 16 mins
2.2 Asthma Therapy 22 mins

5. GI & Endocrine 230m (3h50m)

1) Gastrointestinal 59 mins
1.1 Antiemetic Agents 19 mins
1.2 H2 Receptor Blockers, PPIs 23 mins
1.3 Laxatives & Antidiarrheal Agents 17 mins
2) Diabetes 54 mins
2.1 Insulin, Sulfonylureas, Meglitinides, GLP1, DPP4i 30 mins
2.2 Metformin, Thiazolidinediones, Pramlintide SGLT2i 24 mins
3) Thyroid, Parathyroid, & Adrenal 80 mins
3.1 PTU, methimazole, Levothyroxine 22 mins
3.2 Bisphosphonates, raloxifene, denosumab, calcitonin 18 mins
3.3 Teriparatide, Vit D, Cinacalcet, Sevelamer 19 mins
3.4 Glucocorticoids 21 mins
4) Hypothalamic & Pituitary 37 mins
4.1 GH, Mecasermin, Octreotide, Pegvisomant 19 mins
4.2 ADH, DDAVP, ADH antagonists 18 mins

6. Neuro & Psych 266m (4h26m)

1) Sedative-Hypnotics 47 mins
1.1 Benzodiazepines, Flumazenil 20 mins
1.2 Non-Benzodiazepine Hypnotics 13 mins
1.3 Barbiturates 14 mins

2) Anesthetics & Analgesics 46 mins

2.1 Propofol, Etomidate, Ketamine 10 mins
2.2 Inhaled Anesthetics, Dantrolene 15 mins
2.3 Opiates, Naloxone, Naltrexone 21 mins

3) Antidepressants & Anxiolytics 65 mins

3.1 SSRIs, SNRIs, Cyproheptadine 21 mins
3.2 Tricyclic Antidepressants 16 mins
3.3 MAO Inhibitors 13 mins
3.4 Bupropion, Mirtazapine, Trazodone 15 mins

4) Mood Stabilizers & Antiepileptic Drugs 51 mins

4.1 Lithium 12 mins
4.2 Valproate, Topiramate, Lamotrigine, Levetiracetam 14 mins
4.3 Carbamazepine, Phenytoin, Gabapentin, Tiagabine, Vigabatrin 19 mins
4.4 Ethosuximide 6 mins

5) Antipsychotics & Parkinson’s 57 mins

5.1 First Generation Antipsychotics 20 mins
5.2 Second Generation Antipsychotics 17 mins
5.3 Levodopa/carbidopa, COMTi, Selegiline, Ropinirole, Pramipexole 20 mins
7. Antimicrobials 305m (5h5m)
1) Cell Wall and Membrane Antibiotics 74 mins
1.1 Penicillin 13 mins
1.2 Methicillin Derivatives 6 mins
1.3 Ampicillin, Amoxicillin, Piperacillin, Ticarcillin 13 mins
1.4 Cephalosporins 15 mins
1.5 Monobactams & Carbepenems 9 mins
1.6 Vancomycin 12 mins
1.7 Daptomycin 6 mins

2) Inhibitors of Bacterial Protein Synth 56 mins

2.1 Tetracyclines 13 mins
2.2 Macrolides 7 mins
2.3 Clindamycin 11 mins
2.4 Chloramphenicol 5 mins
2.5 Linezolid 7 mins
2.6 Aminoglycosides 13 mins

3) Antimycobacterials 24 mins
3.1 Tuberculosis Drugs 17 mins
3.2 Leprosy Drugs 7 mins

4) Other Antibiotics 38 mins

4.1 Trimethoprim/Sulfamethoxazole 17 mins
4.2 Fluoroquinolones 12 mins
4.3 Metronidazole 9 mins

5) Antifungals 33 mins
5.1 Amphotericin, Flucytosine 12 mins
5.2 Azoles 12 mins
5.3 Griseofulvin, Terbinafine, Echinocandins 9 mins

6) Antivirals: HIV 33 mins

6.1 NRTIs 11 mins
6.2 NNRTIs 5 mins
6.3 Protease Inhibitors 7 mins
6.4 Maraviroc, Fusion Inhibs, Integrase inhibs 10 mins

7) Antivirals: Hepatitis 21 mins

7.1 Interferon Alpha, Beta, Gamma 10 mins
7.2 Ribavirin, Sofosbuvir, Simeprevir 11 mins
8) Antivirals: Other 26 mins
8.1 Acyclovir, Valacyclovir, Famcyclovir 14 mins
v
8.2 Ganciclovir, Valganciclovir, Foscarnet, Cidofovir 12 mins
v
8. Antineoplastics 129m (2h9m)
1) Antimetabolites 52 mins
1.1 Methotrexate, Leucovorin, 5-FU, Hydroxyurea 29 mins
v
1.2 Azathioprine, 6-mercaptourine, Mycophenolate, Mofetil 16 mins
v
1.3 Cladribine, Cytarabine, Gemcitabine 7 mins
v

2) DNA & Cellular Division 39 mins

2.1 Cyclophosphamide, Ifosfamide, Busulifan, Nitrosoureas 12 mins
v
2.2 Cisplatin, Carboplatin, Oxaliplatin, Amifostine 6 mins v
2.3 Bleomycin, Doxorubicin, Daunorubicin, Actinomycin D 8 mins v
2.4 Etoposide, Teniposide, Topotecan, Irinotecan 6 mins
v
2.5 Vincristine, Vinblastine, Paclitaxel 7 mins
v

3) Kinase Inhibitors & Monoclonal Antibodies 38 mins

3.1 Imatinib, Erlotinib, Sorafenib, Sunitinib, Vemurafenib 15 mins
v
3.2 Rituximab, Cetuximab, Bevacizumab, Alemtuzumab, Trastuzumab 23 mins
v