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Oexle 2019
Oexle 2019
Oexle 2019
CURRENT
OPINION Emerging trends in suicide prevention research
Nathalie Oexle a, Thomas Niederkrotenthaler b, and Diego DeLeo c
Purpose of review
The purpose of this article is to present notable findings and developments in suicide prevention research
and in particular, strategies to detect persons at risk for suicide as well as strategies to reduce suicide risk
among the general population and specific risk groups.
Recent findings
Popular strategies to detect persons at risk for suicide include scanning social media posts, prediction
models using electronic health record data as well as the use of experienced sampling methodology to
enhance our understanding of the suicidal process. Emerging approaches to reduce suicide risk include the
development of media reporting recommendations, mass media campaigns to improve knowledge,
attitudes and behaviour as well as technology-enhanced interventions.
Summary
Recently, promising approaches to detect individuals at risk for suicide as well as effective strategies to
reduce suicide risk emerged. Whether these new opportunities will translate into an effective reduction in
suicide rates remains to be demonstrated.
Keywords
prevention, suicide, suicide risk
decreased and some countries like the United States Franklin and colleagues [7 ] concluded that tradi-
even reported an increase in suicide rates in recent tional suicide prevention research was not able to
years [4]. In general, effective suicide prevention comprehensively identify causal risk factors for sui-
requires strategies to detect individuals at risk as cidal behaviour. Synthesizing results from 365 stud-
well as strategies to reduce suicide risk among the ies from the past 50 years, they found that the
general population and at-risk groups. This article
aims to provide an overview of recent developments
a
in research in both of these domains. We present Department for Psychiatry II, Ulm University and BKH G€ unzburg,
and discuss those topics and studies we felt are most G€unzburg, Germany, bUnit Suicide Research & Mental Health Promotion,
Department of Social and Preventive Medicine, Centre for Public Health,
influential in driving current discussions and devel-
Medical University of Vienna, Vienna, Austria and cAustralian Institute for
opments in suicide prevention research. As a review Suicide Research and Prevention, Griffith University, Queensland,
focusing on emerging trends in youth suicide pre- Australia
&
vention was recently published [5 ], we will focus on Correspondence to Nathalie Oexle, Department for Psychiatry II, Ulm
developments in adult suicide prevention. University and BKH G€
unzburg, Parkstraße 11, 89073 Ulm, G€ unzburg,
Detecting persons at risk for suicide is difficult. Germany. Tel: +49 731 500 62304; e-mail: nathalie.oexle@uni-ulm.de
Merely relying on self-report is error-prone, as sui- Curr Opin Psychiatry 2019, 32:336–341
cidality is often concealed for fear of hospitalization DOI:10.1097/YCO.0000000000000507
&
[17 ,18] as well as the use of experienced sampling
KEY POINTS methodology (ESM) to enhance our understanding
& & &&
Successful suicide prevention requires strategies to of the suicidal process [19,20 ,21,22 ,23,24,25 ].
detect persons at risk as well as strategies to reduce We will present these three approaches and initial
suicide risk among the general population and specific findings in the following paragraphs.
risk groups.
0951-7367 Copyright ß 2019 Wolters Kluwer Health, Inc. All rights reserved. www.co-psychiatry.com 337
and actual suicide risk is needed. Scholars should measuring suicidality at one single point in time
also keep in mind that persons at high risk for suicide only, covering long retrospective periods, and/or
often do not seek help and conceal their suicidality assessing exclusively suicidal thoughts rather than
because of stigma, lack of time, preference for self- suicidal behaviour [29]. To improve suicide preven-
help and fear of involuntary hospitalization [6,28]. tion, information about the short-term predictors
Approaches that include the systematic screening of for suicidal thoughts and behaviour and the factors
social media posts and consequent (unwanted) sup- that predict the transition from suicidal thoughts to
port or even the risk of involuntary hospitalization of behaviour are needed.
persons detected to be at risk for suicide bear the risk One innovative approach with the potential to
of decreasing online help-seeking and disclosure overcome some of these barriers and foster our
when negative consequences are feared. understanding of the suicidal process is the use of
ESM. ESM allows for real-time assessment of suici-
dality as well as its potential correlates and predic-
Electronic health record data tors. In ESM studies, suicidality and other factors of
The detection of factors predicting future suicidal interest (e.g. affective states) are assessed briefly
behaviour is difficult as suicidality is a multifactorial multiple times a day using smartphones or other
phenomenon with a multitude of risk factors work- wearable devices. Initial evidence suggests that ESM-
ing together. In addition, suicide is a rare event and based assessment increases the chance of persons
large sample sizes are required to test the complex correctly reporting their experiences with suicidality
models predicting its occurrence. Owing to their size and does not increase or decrease suicidality among
&
and richness in information, electronic health record participants [19,20 ,21]. Existing ESM-studies showed
data offer the unique possibility to investigate the that suicidal thoughts often occur in brief episodes
predictive power of large numbers of potential risk with quick onset and change even within hours
&
factors simultaneously. In 2017, Barak-Corren and [22 ,23,24]. Additionally, one study reported that
&
colleagues [17 ] analyzed data from almost 2 millions correlates and predictors of suicidality, and predictors
patients derived from two large medical centres in of change in suicidal thoughts need to be distin-
& &&
Boston and found convincing evidence that elec- guished [22 ,25 ]. For example, it seems that hope-
tronic health record data can indeed be used to lessness does correlate and predict suicidal thoughts a
predict future suicide. Their developed model few hours later; however, it seems not to predict
&
included a multitude of potential risk factors (dem- changes in suicidal thoughts [22 ].
ographics, diagnostic codes, laboratory results and ESM offers the novel possibility to provide infor-
medications) and correctly predicted about half of mation about the short-term correlates and predic-
all suicides and suicide attempts occurring within tors of suicidality and therefore improve our
3–4 years after baseline. Those findings were con- understanding of the suicidal process, detect persons
firmed by another study reporting similar results [18] at risk for suicide and foster the development of
and suggest that using electronic health record data effective strategies for suicide prevention. However,
to identify and support persons at risk for suicide existing studies using ESM mostly assessed suicidal
could greatly contribute to preventing suicides. How- thoughts rather than suicidal behaviour, had small
ever, as existing studies did not include representa- sample sizes and followed participants over relatively
tive samples, the general validity of developed short time periods. If future studies address those
models needs further assessment. Furthermore, the limitations, ESM has great potential for generating
potential of electronic health record data to detect knowledge needed for effective suicide prevention.
persons at risk for suicide greatly depends on data
registries actually including data about suicidal
behaviour, which is often not the case. INTERVENTIONS TO REDUCE SUICIDE
RISK
Suicide is a complex phenomenon and its preven-
Experienced sampling methodology tion requires a multitude of strategies working
The field of suicide prevention research is character- together [30]. Interventions to reduce suicide can
ized by great diversity in theories that try to explain be universal (i.e. target the general population),
and predict suicidality. Each theory includes a set of selective (i.e. target persons at risk) or indicated
suicide risk factors, which on their own cannot fully (i.e. target persons already experiencing suicidality).
&&
explain suicide [7 ], resulting in a growing list with However, some interventions can be grouped within
low specificity. One reason for limited knowledge two or more of these domains. Below we present
about the occurrence, course, correlates and predic- recent findings regarding the effectiveness of some
tors of suicidality is because of past research popular strategies to prevent suicide.
nal support for suicide among readers [34]. Although [27,41 ]. Although this might be the case, compre-
earlier studies surprisingly reported that articles hensive evidence for the effectiveness of technology-
including interviews with suicide experts can lead enhanced approaches in reducing suicide risk is still
&&
to imitational suicides [33 ], new evidence supports lacking. Although Internet-based cognitive behav-
the claim that this effect might be because of such ioural therapy (CBT) seems to be as effective as tradi-
articles often also including sensationalist content. tional face-to-face CBT in reducing psychiatric
Several randomized controlled trials found that distress in general [42], in contrast to traditional
stand-alone information about suicide prevention CBT, Internet-based CBT was not found effective in
on websites and in newspapers had beneficial effects reducing suicidality [43]. A systematic review by
in terms of a reduction of suicidal ideation and Witt and colleagues [44] reported some evidence
an increase in suicide-prevention-related knowledge for the effectiveness of online and phone-based
[35,36]. These findings particularly applied to applications for the self-management of suicidal ide-
materials that featured experts and lay individuals ation and self-harm in reducing suicidality [44]. How-
speaking about personal stories of how to cope ever, the authors criticized the low methodological
with suicidality. quality of existing studies and potential biases. In
In summary, available studies support the exis- addition, caution is warranted when implementing
tence of the Papageno effect, but further research is technology-enhanced interventions: when compar-
necessary to identify which specific contents work ing the effectiveness of psychotherapy alone (i.e.
best for various target populations and outcomes treatment as usual) and psychotherapy plus access
such as suicidality, stigma or help-seeking. When to a supportive smartphone app (i.e. LifeApp’tite,
reporting about suicide, journalists should adhere to Aarhus, Denmark) in reducing suicide risk, Toole
&
the updated recommendations recently published and colleagues [45 ] observed smaller decreases in
by the WHO [37]. suicide risk among participants with access to the
smartphone app. In summary, existing studies on the
effectiveness of technology-enhanced interventions
Mass media campaigns in reducing suicide risk were far from being conclu-
With the ultimate goal of reducing suicide, a multi- sive. Although some types of interventions might
tude of social media campaigns to improve suicide- contribute to suicide prevention, others could even
related knowledge (e.g. suicide warning signs), atti- produce unintended harmful effects.
tudes (e.g. to reduce stigma) and behaviour (e.g. to
encourage help-seeking) targeting various audiences
exist. Two recent systematic reviews independently CONCLUSION
concluded that mass media campaigns are indeed an Big data and machine learning hold great promise for
important component of effective suicide prevention suicide prediction. First aid and emergency wards
&
[38 ,39]. However, included studies varied in quality personnel would probably benefit from the availabil-
and reported heterogeneous findings. Although ity of algorithms permitting quick evaluation of their
0951-7367 Copyright ß 2019 Wolters Kluwer Health, Inc. All rights reserved. www.co-psychiatry.com 339
11. Won H-H, Myung W, Song G-Y, et al. Predicting national suicide numbers
clients’ risk of suicide. Wearable technologies are & with social media data. PloS One 2013; 8:e61809.
currently used for checking heart and blood pressure, One of the first studies assessing the link between suicide-related social media
posts and national suicide rates.
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forums: proof-of-concept study. J Med Internet Res 2018; 20:e215.
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Ment Health 2016; 3:e21.
Mass media campaigns could have similar effects, This study is the first to assess the association between suicide-related social
but more research is needed. Finally, some technol- media posts and individual suicidality.
16. Bryan CJ, Butner JE, Sinclair S, et al. Predictors of emerging suicide death
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17. Barak-Corren Y, Castro VM, Javitt S, et al. Predicting suicidal behavior
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This study used a large data set derived from electronic health records and
an effective reduction in suicide rates remains to be developed a model that correctly predicted half of all suicides occurring within the
demonstrated. study period.
18. Simon GE, Johnson E, Lawrence JM, et al. Predicting suicide attempts and
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Acknowledgements Psychiatry 2018; 175:951–960.
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Conflicts of interest suicidality among respondents.
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0951-7367 Copyright ß 2019 Wolters Kluwer Health, Inc. All rights reserved. www.co-psychiatry.com 341