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LM - Lab Design - eBOOK - JL
LM - Lab Design - eBOOK - JL
❱ From Collaboration to
Miniaturization
LAB DESIGN
RESOURCE GUIDE
Lab Design Resource Guide
Five Tactics for parameters are an essential tool for guiding the evaluation of
potential sites and/or (re)designing the new environment.
Kicking Off Some teams benefit from a series of client/design team work-
shops where the designers can establish a holistic understand-
Laboratory
long-term goals. This may include interviews related to the
company’s goals and program needs that will help inform the
design team on functional and adaptable space and design
Design Project needs for labs and offices as well as mechanical, operation-
al, and building systems, ancillary and amenity spaces, and
other areas.
With many individuals participating in the project, it
These sessions are an effective way to explore critical infra-
is important to get on the same page from the start
structure considerations, phased stages, adaptable spaces,
by Robert Skolozdra project constraints, budget parameters, and scheduling op-
tions. This preparation can go a long way toward ensuring the
Successful laboratory design requires a common vision lab’s design ultimately results in a superior environment that
among the design, management, and consultant teams. Many advances productivity and promotes staff morale.
factors are at play, including funding, location, staff well-be-
ing, local regulations, equipment needs, programming, future 2. Build a design budget
growth, and the like. With many elements to weigh and so
much at stake, considering these tactics might help start you Budget considerations require the assessment of costs
in the right direction. involved for each stage of the project, including the design,
consultant fees, materials, and labor. Creating a detailed
1. Clarify the scope of the job matrix for each of the project’s different aspects not only as-
sists with high-level planning but also provides cost analyses
A critical step is ensuring the client organization has clear ob- for each space type. To keep the information relevant and
jectives and a consensus-driven vision for its future. As orga- useful, update the matrix as the design expands and evolves,
nizations change and grow, their needs do as well. It’s critical including cost drivers like casework, engineering needs, and
for stakeholders to be on the same page prior to launching the architectural elements.
design phase of a project.
3. Select the right colleagues for the job
At this early stage, programming details and locations need to
be established. Is the project a redesign of an existing building The design lead for the project will need to establish a
or the design of a whole new facility? Whether or not the cli- well-balanced design team for the project to meet the lab’s
ent is considering a new location, well-documented program demand for a highly technical space that’s responsive to the
Lab Manager 2
Lab Design Resource Guide
client’s present needs and can meet future demands. A project (with the link included), an in-person meeting at a specified
manager experienced in laboratory planning and design is place, or a hybrid gathering.
essential, as are architects and designers who specialize in
effective and welcoming laboratories similar in scope to the 5. Communicate and negotiate with effective
one being designed. Support staff and proven consulting firms strategies
also smooth the way.
It’s important to maintain open, productive communications
4. Host a stakeholder kickoff meeting throughout the design, construction, and move-in phases
of the lab design project. Scheduling regular meetings after
An organized kickoff meeting establishes where and how the kickoff session ensure a consistent approach to the lab’s
the lab will be designed among the project’s stakeholders, design in a timely, efficient, and cost-effective manner. It also
including the architecture and design lab team, the labo- furthers the resolution of design, technical, and construction
ratory’s steering committee—chief executive officers and challenges that may be encountered during the process.
facilities director—and the lab’s departmental directors and
staff, as required. Essential topics should be covered during To keep meetings timely and productive, take steps to keep
the session and the initial steps involved in the project should attendees on topic. Sharing agendas early on is an effective
be put into motion. means to ground meetings in key aspects of the project and
to hold participants to the topic at hand. Make sure the team’s
To best prepare for this kickoff meeting, the architecture supporting members take notes on shared comments, input,
firm’s project manager may want to schedule a preliminary and subsequent steps for discussed topics.
in-house session with the designated design team to out-
line the topics to be covered in the kickoff meeting, issues Often, materials that support the concepts addressed will
related to each topic, and possible options to meet the named need to be prepared and included in the meeting and later
objectives. This sets up mutually agreed parameters among sessions. It’s helpful for the design team to share essential
the architecture and management groups for the lab design content in various visual formats for a complete and holistic
team to later deliver an effective design program in a timely view of the project’s critical requirements. In addition to the
manner, including a review of space allocations, listed and agenda, this could include electronic or physical diagrams
diagrammed rooms, technical criteria for each space, prelimi- involved in planning the project, along with preliminary
nary area projections, and preliminary costs. layouts, spreadsheets, and charts to make it easier for the
meeting’s participants to understand proposed ideas.
Once the topics and issues have been outlined, the lab design
team should share this agenda with the meeting participants Planning for something new is exciting, especially when it’s
prior to the session, allowing everyone to see what will be for the creation of a new, renovated, or adaptive reuse of space
discussed and giving them the opportunity to add areas of for a state-of-art lab that advances life-changing research and
interest to the program. The agenda also informs all the innovation. Whether it’s the design of a 150,000-square-foot
meeting’s participants of when the session will take place, lab and research facility or a start-up lab’s two-bench space,
how long it will be, and whether it will be a video gathering laboratory environments that are efficient, safe, and comfort-
able start with significant planning and communication.
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Lab Design Resource Guide
Leading a Lab how to maximize them, and form a holistic team that comple-
ments each other. The most effective collaborative part-
Design Team
nerships have a rhythm and shared language that improves
communication and effectiveness.
Once you understand the unique needs of the organization, Resolving complications
putting together the best team of experts is crucial. It helps to
have specialty consultants you know and with whom you like Notably, effective project leaders for the design of research
to work. Team leadership should understand their strengths, settings understand the technical and engineering compo-
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Lab Design Resource Guide
nents involved, including the standards and codes specific to Delegate tasks appropriately for top outcomes. Keep a finger
lab design and construction. But more importantly, they seek on the pulse of team interactions, personalities, and work
the expertise of relevant consultants when issues arise. Egos habits to stay ahead of potential problems. Some people, for
need to be checked at the door. instance, are highly organized. Some prefer email and text
communications to telephone calls. By understanding people’s
Consider a project where zoological research is being con- strengths, weaknesses, and work styles, design leaders can
ducted, and the team identifies excessive vibration levels in anticipate where to fill in gaps and can maximize their team’s
the building that may adversely affect the breeding habits of talents for better outcomes overall.
subject animals. The problem may be related to the building’s
structure, or to mechanical, electrical, and plumbing (MEP) Creating a diverse and inclusive work
or heating, ventilation, and air conditioning (HVAC) systems. environment
The leader’s job is to consult with all relevant team members
in a coordinated effort to identify the problem and devise Diversity is critical to all fields, especially those focused on
a range of solutions. Building good relationships with team complex problems. Indeed, despite the mythology of the
members early in the process will undergird problem-solving singularly brilliant scientist (think Einstein), innovation is
efforts like these. Showing them that they’re respected and rarely driven by a solitary person. People from different
valued may inspire a greater willingness to put in extra effort backgrounds, on average, tend to approach problem-solving
as needed, which in turn leads to better outcomes. differently, and it is this diversity of perspectives that often
leads to breakthroughs.
Every project has its challenges. Construction issues arise,
field conditions change, mid-stage drawing and plan adapta- While the architecture field has become more diverse in the
tions occur, and conflicting points of view emerge. Each team last 30 years, there is still more work that needs to be done.
member is responsible for individual contributions to the Firms will benefit from creating an internal diversity, equity,
resulting laboratory design, but team leaders are responsible and inclusion committee to look at office policies and hiring
for everyone’s contributions, including their own. The follow- practices, as well as ways to support equity in the career
ing guidelines help ensure productive collaboration toward pipeline. Look for ways to increase your outreach to attract a
workable solutions and forward momentum: broader range of talent and support the work-study programs
of local, low-income high schools, bringing in students to ex-
• Be realistic with expectations and deliverables. pose them to the architecture, engineering, and construction
industry. You might also consider contributing to the growth
• Mitigate crises by listening to details surrounding the of a state organization—for instance, your local chapter of
situation, acknowledging them, and moving forward with NOMA (National Organization of Minority Architects).
a solution. Pointing fingers doesn’t resolve issues. Rec- These are not initiatives specific to lab design but enhancing
ognizing the challenge for what it is and working across the diversity of your team is key to long-term growth and
functions to find a workable solution should always be competitiveness across all your sectors.
the focus.
Not everyone fits in the same box, and that’s a good thing.
• Recruit outside help as needed to get a job done well. Rec- Each person brings a specific set of skills, personality, and
ognize it’s better to ask for assistance sooner rather than background that adds to a team’s effectiveness and creates
later to avoid the potential bigger problems of unexpected a balance within it. Lab design teams need each person’s
delays and cost overruns. unique talents—whether they’re technical, managerial, or
creative—to balance a group’s contributions and contribute
to a lab’s success.
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Lab Design Resource Guide
Using Digital plying digital tools to streamline lab design and construction
is a key part of shortening the time it takes to get new drug
Delivery to
products to market.
Design and
ability to clearly communicate design intent with laboratory
management and scientific users. Sometimes, designers who
are too familiar with design documentation forget to trans-
Construction 4.0—a combination of innovative technologies, Two important innovations that emerged during the
data, and digital tools—is transforming the architecture, COVID-19 pandemic have sped up and improved lab design
engineering, and construction (AEC) industry, particularly in and construction: advances in cloud-based software capabili-
the development of life sciences labs. A recent survey found ties, and the willingness of lab owners to try out new project
that 40 percent of 500 executives in the life sciences industry, delivery methods. Traditionally, AEC firms designed an en-
who took part in the survey, identified speed-to-market, not tire lab project before releasing it to fabrication and construc-
cost, as their number one priority. Applying digital tools to tion teams. Separately, these trade contractors traced over and
streamline lab design and construction is a key part of short- (in many cases) heavily modified the model to achieve a fabri-
ening the time it takes to get new drug products to market. cation level of detail. An integrated project delivery mindset
and virtual design and construction (VDC) processes allow
Anyone involved in the design and construction of a lab in the architects, engineers, subcontractors, and vendors across
last 10 years will likely be familiar with building information multiple locations to work together using a single model, both
modeling (BIM). But what may be news to some lab managers simultaneously and in sequence.
is that BIM is just one small piece of what is now possible with
digital delivery. Today, using digital technologies to integrate Integrating trade partners and co-authoring design and con-
work processes and connect stakeholders removes barriers struction models early is important to the faster delivery of
and allows the design and management teams involved in the better projects. While the AEC firms create the overall vision
project to save time, communicate clearly with each other, and own the model, construction trade partners offer invalu-
and deliver excellence on capital projects. For example, ap- able feasibility input and can help fully develop the model
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Lab Design Resource Guide
to constructability during the design phase. This approach • Tablets, drones, construction cameras for live feeds and
creates a shared sense of ownership and helps preserve the time-lapse videos, and 360-degree cameras that stitch
design intent while eliminating duplication of work. together photos and tie them to the plans are all examples
of field technologies. These tools provide a vital link from
Utilize new advanced technology tools the field to the AEC firm and its partners, as well as infor-
mation on construction quality, safety, and security.
Digital delivery is the future of this business, and the future
is here today. Thanks to advances in technology, design teams Experts state that clients have responded positively to the
can now work in intelligent 3D design models, allowing them use of BIM since the system allows them a glimpse of what
to share work in real time between multiple offices and stake- their lab will look like before the building process even gets
holders. There are several options available: underway. This greatly reduces costly downtime and do-
overs if something doesn’t meet their expectations. It has also
• Advanced 3D authoring tools aid in the analysis and become commonplace for clients to request a walkthrough of
understanding of layouts, points of use for utilities, and the 3D version of their space with their users. This ensures
where to route systems. They also allow teams to identi- that users get everything that they need relevant to casework
fy conflicts in models to prevent potential issues during and equipment layout while obtaining a visual understanding
construction. of how they can use their space before the plans are sent for
permit review and construction.
• Reality capture tools are important to consider when
renovating or fitting out existing buildings. Photogram- Digital delivery is here to stay
metry, light direction and ranging, laser scanning, and
3D mapping are all tools that can help accurately capture Advanced technologies, a global pandemic, and a growing
existing site conditions and infrastructure by producing a need to focus on speed-to-market for life-saving treatments
rendering that is integrated into the 3D model. have significantly changed the AEC industry. Digital delivery
is the future of this business, and the future is here today.
• Augmented reality and virtual reality help eliminate bot- Collaborating with experienced partners early in the design
tlenecks, improve collaboration, and allow lean delivery. process and leveraging VDC has changed the way companies
For many project teams having to deal with local lock- work by making the construction and fabrication consider-
downs or travel restrictions during 2020, these technolo- ations an innate part of the design. Designing with construc-
gies went from excellent options to mandatory tools. tion in mind delivers the best of both worlds: lean projects are
completed faster.
• 4D BIM adds detailed scheduling to the construction
sequence and installation of a proposed lab or plan the Designing in BIM makes it easy to quickly show different
phased occupancy in a renovation, retrofit, or addition. 5D design options for a project. As industries and technologies
BIM adds cost estimation to the model. 4D and 5D BIM advance at a rapid speed, equipment needs of the client post
allow AECs to generate accurate model-based quantity day one may not remain the same in the years to follow. BIM
take-offs and cost estimates throughout the project’s entire helps demonstrate the potential of the client’s space and how
lifecycle. Estimators can develop and confirm estimates they can act when unknown changes arise, instead of being
based on the model, measure performance against targets, stranded in a position to have to react to these changes as
and anticipate any changes in timing and costs before they occur.
they occur.
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Product Spotlight
Begin Your Journey with Digitalization
Managing the lab involves overseeing daily You can ensure the safety of your samples by
activities and ensuring that all processes are responding to alarm notifications and addressing
running smoothly. All equipment must be any issues quickly. Additionally, the platform can
maintained properly to limit downtime and any be utilized to plan for upcoming maintenance
workflow interruptions. Devices for storage also activities of your devices. By keeping up with
require monitoring to prevent issues that can service for all lab equipment, you can keep your
cause sample ruin. By implementing a digital instruments performing optimally. Connecting
solution such as VisioNize® Lab Suite, you can your devices to VisioNize® Lab Suite can help
manage your lab with one platform. Monitor you manage your lab more effectively.
your entire fleet of freezers from anywhere
and receive real-time notifications of device
temperature fluctuations and power failures. LEARN MORE
Track all related device parameters such as
temperature, O2 and CO2 of your incubators.
Lab Design Resource Guide
Five Things Just as humans are motivated to fulfill their needs in a hi-
erarchical order, moving from the most basic need to more
Every Lab
advanced needs, we have identified five ways scientific facility
design can help improve the workplace experience from a
holistic, humanistic perspective.
Doesn’t Have The bottom tier of Maslow’s hierarchy contains the most
essential things a person must have to survive, including the
physiological needs of air, food, water, and shelter. In a typical
Create a comfortable environment that fulfills basic interior space, this means acoustic comfort, high air quality,
human needs and encourages productivity cleanliness, daylighting, thermal comfort, and nourishment,
all of which have been proven by research to improve health
by Isabel Mandujano and Rachel Nasland
and contribute to productivity.
Safety and workflow efficiency are frequently the first priori- Nourishment is a critical, yet often overlooked, physiological
ties in the design of a laboratory facility. Given the rigor and need in lab spaces. Given the 24/7 nature of scientific work,
systematic processes that science requires, the humanistic where it may not be possible or prudent to leave the building
aspect of the scientist is often neglected. However, the recent and access off-site food at odd hours, it’s especially import-
climate and the pandemic have brought to the forefront the ant that companies focus on nourishment. It’s also often not
importance of incorporating health and wellness, inclusive possible to bring food and beverages into the lab for safety
design, and a vibrant culture to attract and retain the best reasons, making it even more important to provide designated
talent. If workers are not provided with a comfortable envi- spaces for employees to step out of the lab to eat and drink.
ronment that fulfills basic human needs, then regardless of the This nourishment space can also serve as a social place where
rewards and recognition, they will be dissatisfied with their scientists can interact with other people who might work out-
environment and unlikely to be at their most productive. side the lab. Coupled with the opportunity to open a window
or step outside, it can also deliver the added benefits of access
There are a host of challenges to improving working condi- to daylight, fresh air, and contact with nature.
tions in controlled scientific environments, but the benefits
are well worth the effort. Scientific workplaces designed to One way we are using design to help encourage healthy
satisfy each tier of Maslow’s hierarchy of needs (physiological, choices is by adding full kitchens complete with stoves,
safety, love/belonging, esteem, and self-actualization) can fridges, and ovens to break rooms. This allows people to cook
increase employee well-being, improve company culture, and a healthy meal for themselves or their coworkers using fresh
facilitate scientific innovation, discovery, and exploration. Ul- ingredients. In addition to the health benefits, cooking can
timately, it results in better outcomes for the people that work bring coworkers together and strengthen the culture. Healthy
in the space, their work, and the community. vending machines filled with freshly prepared meals are
another way companies can encourage employees to enhance
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Lab Design Resource Guide
their nourishment in a convenient way. Bowls of fresh fruit cognition and psychological well-being. In fact, one study
in the kitchen, as well as grab-and-go cafes stocked with quantified the benefit by demonstrating that employees who
fresh food, are other strategies for supporting the health and had views of nature took nine fewer sick days, on average.
well-being of employees.
Especially given the potentially hazardous nature of working
Safety in a lab, it’s critical to provide an environment that enhances
cognitive function and improves well-being.
The second level of Maslow’s hierarchy of needs relates to
physical and psychological safety and security, including pro- Love/Belonging
tection from potentially dangerous or threatening environ-
ments. In lab design, ensuring a safe and secure working envi- Next on the hierarchy of needs is love/belonging. When it
ronment is often the top priority. However, when safety needs comes to laboratory work, this can be accomplished by cre-
are not met, it can make users uncomfortable and contribute ating spaces that allow for social interaction and connection,
to a stressful environment, impeding workers’ productivity. which has a positive impact on mental health and commu-
While there is extensive information available about how to nity (or workplace) resilience. When employees are given
manage potential hazards in a lab, one overlooked factor is the opportunity to collaborate, relax, and socialize with one
how safety can be enhanced through design. another, it has a positive impact on productivity, innovation,
and mental health.
Adding color and contrast is one strategy to enhance safety
and improve wayfinding. For example, an emergency shower We often hear from scientists that it’s difficult to have an
surrounded by a pop of color makes it easier to find. Colorful impromptu meeting or discussion because of the need to take
lines on the floor can indicate which areas need to be kept off protective equipment and reserve a conference room po-
clear of equipment, boxes, or furniture so occupants always tentially far from the lab. Because of this, collaboration among
have a clear walking path free of obstructions and easy access scientists happens far less frequently than desired. To solve
to emergency exits. Colors on the wall can also help users this, we frequently add a breakaway area directly adjacent to
easily identify the different departments in a lab space. Color the laboratory space where colleagues can quickly bounce
has the added benefit of providing more visually stimulating ideas off one another, meet about a project, or have a virtual
spaces that combat boredom, improve concentration, and call with someone offsite. This gets workers out of their chairs
bring a sense of liveliness to the space. more frequently as well, which has added physical and mental
health benefits.
Biophilic design, the incorporation of nature or features
that resemble nature, is another strategy that is proven to Communicating stairs are another design feature that en-
improve mental functioning, reduce stress, and lower illness hances the sense of belonging. More than just a way to move
and absenteeism, all of which contribute to a greater sense from floor to floor and get your steps in, they serve as a space
of safety and security for occupants. While live plants can’t for all-hands events, eating meals, meetings of all sizes, and
be added to lab space, design can mirror and resemble forms community events. A design element that is front and center,
of nature. Biophilic elements can be incorporated through it encourages people to collaborate and connect both with
plant-inspired finishes and shapes, wood-inspired flooring, coworkers they know well and those they wouldn’t typically
and other elements that remind occupants of nature while interact with by creating curated collision zones.
still being easily cleanable. This connection to nature further
increases stimulation and comfort for workers in an otherwise Esteem
sterile setting.
Esteem, which focuses on choice, purpose, and achievement,
When appropriate for the work at hand, adding windows with is another critical component of laboratory design. When
views of nature is extremely beneficial. Looking through a people can choose what space best accommodate their work
microscope at slides or pipetting into test tubes for much on any given day, it enhances productivity and improves
of the day requires extreme precision and focus, which can well-being. In a scientific workplace, this means that the
be mentally demanding and draining. Having the ability to industry is moving away from individual assigned bench
look up and view nature through a window, especially if you space, and instead providing areas assigned to instruments,
can’t physically go outside for a break, provides a much-need- so scientists have the flexibility to choose workspace depend-
ed mental rest that restores attention and memory. Even a ing on their activity. This could mean an employee works in
15-second break to view nature has been shown to enhance an instrumentation room one day, in a technology-enabled
Lab Manager 10
Lab Design Resource Guide
space on computational models or simulations the next, and qualities in the workplace by creating calming spaces for
outdoors collaborating with colleagues the following day. respite, relaxation, and meditation. Nap pods are one option
With more scientific work becoming data-driven, it’s criti- that allow employees to escape from the stressors of the lab
cal to provide ample private space for heads-down focused for a quick rest, promoting investment in personal well-being.
work as well. Zen gardens filled with native vegetation and walking paths
are another way to allow workers to disconnect from the high
Outdoor space is an important component of providing demands of the lab, which often leads to increased reflection
options for both collaborative and focused work, as well as and “a-ha” moments. Cozy seating areas, both indoor and
respite and socialization. When fully enabled with Wi-Fi and out, invite employees to take time for themselves and connect
power connections, outdoor areas serve as an enjoyable en- with colleagues, while also providing a choice of environment
vironment for a Zoom call, focused data analysis, or working to accommodate a varied range of needs and preferences
session with a colleague. Outdoor areas provide stress-reduc- on any given day. These strategies serve to support policies
ing benefits of nature and fresh air while serving as collision and programs that allow companies to invest in encouraging
zones that encourage interactions and collaboration between employees to develop their whole self, improving overall
departments. They provide space for the company to connect satisfaction and motivation.
with the surrounding community as well.
In summary, when scientific workplaces are designed around
Thoughtful branded environments can provide scientists the five pillars in Maslow’s hierarchy, it increases employee
with sense of purpose in their work and help foster a sense of well-being, happiness, and productivity while improving
achievement, connecting their day-to-day work to the broad- company culture. This ultimately helps companies attract and
er impact on the community. retain top talent and foster the innovation and discovery that
is so important in this industry.
Self-actualization
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Lab Design Resource Guide
Collaboration
be more integrative to include spaces that allow for com-
munication, active collaboration, focus and analytical work,
exploration, and experimentation amongst teams. Consider
Miniaturization
An increase in digital collaborations
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Lab Design Resource Guide
Tissue culture is on the rise Hotdesking and the blurred lines of the
workplace
A surge in therapies for cancer and neurosciences, devel-
opment of novel vaccines, growing focus on personalized While work in the lab environments may go back to “normal,”
medicine, continual R&D in drug discovery, and overall the idea of hybrid work models does not seem to be going
awareness about cell culture techniques that can be used in away. As we look at ways to improve overall space utilization
various areas of research have resulted in a growth of tissue and space quality, we are seeing a shift to more hotdesking
culture work. Although 2D cultures are preferred methods where one can pick a space based on their specific needs,
and typically used, significant growth in other techniques whether it is proximity and visibility to a lab bench and/or
such as 3D cell cultures, organoids, and 4D cell cultures are a desire to feel safe, both physically and psychologically, by
providing new models between the historical 2D cell culture keeping distance from the next person. As work processes
and animal models. become more digitized and automated, time spent in the lab
proper will likely be reduced.
Design/planning response: Understanding the type of cul-
ture (mammalian vs. non-mammalian) and the specific kind Integrative research environments should be inclusive of the
(i.e., clean, infectious disease, bacterial, viral vector) is im- traditional office and workplace. Accommodating a variety of
portant to accommodate for specialized protocols, equipment, workplace environments that allow for focused work, col-
and ventilation requirements to help prevent contamination laboration, experimentation, and computation with varying
between samples and allow for specialized protocols that may amounts of technologies and qualities of spaces will allow
be required. staff to choose the appropriate workplace setting based on the
task to nurture innovation, collaboration, transformation, and
foster a positive culture.
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Lab Design Resource Guide
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Lab Design Resource Guide
Featured
Manufacturer
Eppendorf is a leading life science company that develops and sells instruments, consumables, and services for liquid-,
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ture freezers, fermentors, bioreactors, CO2 incubators, shakers, and cell manipulation systems. Consumables such as
pipette tips, test tubes, microtiter plates, and single-use bioreactor vessels complement the range of the highest-quality
premium products.
www.eppendorf.group/w2ruv6
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