Critical Care >Outcomes Research and Reporting

John M. Oropello, Stephen M. Pastores, Vladimir Kvetan+

Table 87–1A comparison of features between traditional clinical research and outcomes research.)

Traditional Clinical Research Outcomes Research

Efficacy Effectiveness

Mechanisms of disease Impact of disease on the patient

Experimental Observational

Feasibility Cost-effectiveness

The effect of biochemical and physiologic factors on biophysiologic outcomes The effect of socioeconomic factors on patient-centered outcomes

Disease-centered Patient- and community-centered

Provider-oriented Consumer-oriented

Inventing technology Assessing technology

Drugs and devices Processes and delivery of care

Methods from the “hard” sciences (physics, biochemistry, physiology) Methods from the “social” sciences (economics, social and behavioral sciences, epidemiology)

Reproduced with permission from Rubenfeld GD, Angus DC, Pinsky MR, et al: Outcomes research in critical care: Results of the American Thoracic Society critical care assembly workshop on outcomes research,
Am J Respir Crit Care Med 1999 Jul;160(1):358-367.

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