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PRÁTICA DE TRADUÇÃO
Neuro - Oncology
The program offers a
consulting service that
includes evaluation,
discussion, and a second
opinion. In what are
called Integrated Clinics,
which are in the Morumbi
Unit, the service is
performed simultaneously
by a team composed of a
clinical oncologist, a neuro-
oncologist, a neurosurgeon,
a radiotherapist and a
nurse, based on the prior
review of the imaging and
pathology by a neuro-
radiologist and a neuro-
pathologist. Every
Thursday at noon there are
also multidisciplinary
meetings - Tumor Boards -
for discussion of cases with
tumors of the nervous
system.
Center of Excellence in
Memory (NEMO)
The NEMO has a team of
highly specialized
professionals who use high
technology techniques to
reach the earliest possible
diagnosis of the disease and
the appropriate treatment
to ensure a better quality of
life for patients and their
families. This Center
provides a second opinion
service with a specialized
neurologist in the Morumbi
Unit.
Multiple Sclerosis
In the Multiple Sclerosis
Center at the Hospital
Israelita Albert Einstein,
the patients receive
complete care including
diagnosis, treatment, and
daily monitoring. The care
includes, among other
things, recommendation
for auxiliary therapy, a
second opinion service for
physicians regarding
treatment, the early
identification of any
therapeutic failure,
identification of adverse
effects, and improved
patient adherence to the
recommended treatment,
in addition to early
identification of possible
serious complications
arising from
immunosuppressant
treatments.
Quality Certificates -
Neurology
Stroke is the leading cause
of disability in this country,
and our Sstroke Center
was the first center in Latin
America to have a specific
certification from the Joint
Commission International
(JCI), the most respected
certifier of quality in
medicine in the world.
Prompt Intervention
One of the critical factors
for patients who show signs
and/or symptoms of a
stroke is the promptness of
care. The quicker the
intervention, the greater
the chances of the patient
evolving without sequelae
and , having a shorter
hospital stay. One of the
indicators of Einstein
Neurology Program –
Stroke is the time between
arriving at the Emergency
Care Unit (UPA) and doing
a tomography, when
recommended.
Immediate Diagnosis
For a patients with signs
and/or symptoms of stroke,
time and diagnostic quality
are fundamental to the
establishment of
appropriate treatment.
Einstein Neurology
Program – Stroke offers
state-of-the-art equipment
and a specialized team in
neuroradiology: magnetic
resonance imaging with
diffusion and perfusion,
echocardiograms,
angiotomography,
ultrasound, and it also has
interventional
neuroradiologists. Through
the implementation of a
structured report and of a
standardized way of
looking at the tests, it is
possible to maintain speed
and accuracy of diagnosis
with maximum quality.
Stroke Center
Contact: 2151-1301
Hours: Monday through
Friday: from 8 AM to 6
PM
For emergencies: 2151-
1301
CALL CENTER
55 11 2151-1233
CONTACT US
Send us your comments
and suggestions
Stroke/Cerebrovascular
accident (CVA)
Stroke (CVA) is a medical
emergency and can be
effectively treated if the
patient is quickly routed to
an appropriate hospital.
Early recognition of signs
and symptoms, a rapid
neurological evaluation,
and an imaging
examination (tomography
or magnetic resonance
imaging) are essential for
survival. After the imaging
exam it is possible to
determine whether the
patient has had an ischemic
or hemorrhagic stroke.
The treatment of ischemic
stroke, used around the
world for many years, can
be done with a
thrombolytic agent
administered into the
patient’s vein. The function
of the drug is to dissolve
the blood clot that is
clogging the intra-cerebral
artery and causing
ischemia. Ideally the
deadline for beginning the
drug treatment is four and
a half hours after the first
symptoms.
Control
Treating a hemorrhagic
stroke is more complex and
requires the patient to be
admitted into a critical
care unit with neurological
monitoring capacity. In
such a specialized unit, it is
possible to properly control
blood pressure and any
alterations seen during the
neurological exam. In some
cases, neurosurgery may be
needed, which demands
agility from the hospital to
get a rapid assessment
from the neurosurgeon.
Neuro-Oncology
Neuro-Oncology at the
Hospital Israelita Albert
Einstein offers an excellent
infrastructure for
diagnosing and treating
patients with tumors of the
nervous system, with a
highly specialized medical
staff and the latest
generation equipments. A
partnership with the MD
Anderson Cancer Center
(Houston, Texas), one of
the largest hospitals in the
world, specialized in the
treatment and research in
oncology, contributes to the
continuous improvement
and guarantees the
excellence of medical
services and care provided
to our patients.
The program offers a
consulting service that
includes assessment,
discussion, and second
opinion. In what are called
Integrated Clinics, located
at Morumbi Unit, the
service is performed
simultaneously by a team
composed of a clinical
oncologist, a neuro-
oncologist, a neurosurgeon,
a radiotherapist, and a
nurse, based on the prior
review of imaging and
pathology by a
neuroradiologist and a
neuropathologist. Every
Thursday there are also
multidisciplinary meetings
- Tumor Boards - for
discussion of cases of
tumors of the nervous
system.
The Neuropediatric
oncology service also has a
highly specialized team.
Diagnosis
Neuroimaging
The neuroimaging service
at Einstein is composed of a
multidisciplinary team that
seeks to deliver the best
quality exams for the
diagnosis, treatment
planning, and follow-up of
patients with tumors of the
central nervous system.
The hospital has modern
equipments of Magnetic
Resonance Imaging (1.5
and 3.0 Tesla) and
Computed Tomography
(CT), as well as hybrid
equipment (PET/CT and
SPECT/CT – and, since
2015, it has PET/MRI), in
order to produce the main
imaging exams used for
these patients:
• Computed Tomography
• Magnetic Resonance
o Conventional Magnetic
Resonance
o Brain Perfusion and
Proton NMR Spectroscopy
o Functional magnetic
resonance imaging: pre-
intervention brain
mapping
o Tractography: pre-
intervention brain
mapping
• Nuclear Medicine /
Molecular Imaging
o Glucose metabolism with
18F-FDG PET/CT
o Gallium metabolism
PET/CT
o SPECT/CT cerebral
blood flow
o (Tc-TRODAT)
dopamine transporter
SPECT/CT
o 18-FDG PET/MR for
glucose metabolism
o PET/MRI metastases of
prostate CA (GA-PSMA)
o PET/MR somatostatin
analogues (Ga -
DOTATATE)
All tests performed in our
department are stored in
digital format (PACS) at
the hospital’s own servers,
allowing quick access and
retrieval if necessary,
facilitating an evolutive
analysis and comparison
between the different
modalities.
All physicians involved
have specific training in
neuroimaging and, in the
case of hybrid methods, the
interpretation is made
jointly by teams of
neuroradiology and
nuclear medicine, always
with the goal of
maximizing the quality and
reliability of each method.
• CSF
• Electrophysiological
studies (EEG, evoked
potential, ENMG)
• Neuropathology
Pediatric Neurology
Some neurological diseases
are common in childhood
and adolescence:
meningitis, encephalitis,
epilepsy, sleep disorders
(somnambulism, for
example), muscular
diseases, and headaches,
among others.
Neuropediatrics is the
branch of neurology that
studies these and other
diseases of the development
and maturation of the
nervous system.
Causes
The disease may have
several causes that vary
according with the type of
epilepsy and with the age of
the patient. In children, for
example, neonatal anoxia
(lack of oxygen in the brain
during childbirth) and
inborn errors of
metabolism (metabolic
alterations that have
existed since birth) are
frequent causes of epilepsy.
In the elderly, on the other
hand, cerebrovascular
disease (stroke), as well as
brain tumors, are some of
the most frequent causes.
Signs and Symptoms
There are several types of
epileptic seizures, each
with different
characteristics. One of the
most common types is the
generalized tonic-clonic
seizure, usually simply
called "seizure." This type
of episode is easily
recognizable because the
patient presents
generalized muscle spasms,
sialorrhea (excessive
salivation), and often bites
his tongue and loses urine
and feces.
Treatment
Epileptic seizures are
treated with the use of
specific medications, called
antiepileptic drugs. There
are more than 20 drugs
currently available for the
treatment of epilepsy—not
all are sold in Brazil.
With the clinical treatment
(with anti-epileptic drugs),
about two-thirds of
patients have their seizures
controlled. A significant
number – about a third –
continue having seizures in
spite of the clinical
treatment.
It is important to highlight
that the majority of people
with epilepsy have their
seizures controlled with
pharmacological treatment
and therefore may have a
normal life with little or no
limitation. The recognition
of the episodes and the
correct diagnosis allow the
best treatment to be started
early so that the patient
may resume his or her
normal activities.
Prevention
Some causes of epilepsy
such as neonatal anoxia or
cerebrovascular disease
can be prevented. Thus,
proper prenatal care and
good labor care can
certainly help to reduce the
number of cases of epilepsy
related to childbirth
problems.
In the same way, suitable
control of risk factors for
cerebrovascular diseases
such as hypertension and
diabetes can help reduce
the number of strokes,
thereby reducing the cases
of epilepsy caused by this
disease.
Neuromuscular Diseases
Neuromuscular diseases
(diseases of motor neurons,
the cervical plexus, and the
lumbosacral spine) affect
the peripheral nervous
system, which is composed
of muscles, peripheral
nerves, and neuromuscular
junctions.
The most common are:
diabetic neuropathy as well
as other peripheral
neuropathies and
myopathies (muscle
diseases), myasthenia
gravis, and amyotrophic
lateral sclerosis (ALS).
Treatment
The Hospital Israelita
Albert Einstein has a team
of physicians specialized in
the neuromuscular area
and a cutting-edge
infrastructure to perform
all the laboratory tests that
are important for
diagnosing these diseases.
Rehabilitation is also an
advantage offered by the
hospital, which has a
multidisciplinary
rehabilitation team
specializing in
neuromuscular diseases.
Sleep Disorders
The required amount of
hours of sleep varies
according to age. However,
frequent symptoms such as
persistent fatigue,
irritability, lack of
attention and a drop in
productivity should be
observed carefully - they
may be signs of sleep
disorders. In more severe
cases, patients may even
present cardiovascular
disease and depression.
The medical world
recognizes three main
groups of sleep disorders:
- insomnia
- excessive sleepiness
- abnormal behaviors
during sleep
Sleep is a natural
behavioral state and is
essential for the proper
balance and functioning of
all our organs and systems.
Sleep disorders, then, are
those conditions that
interfere with this balance
and have a consequent
impact on our health and
quality of life.
There is increasing
scientific evidence of the
impact of sleep disorders
on cardiovascular diseases
(cases of coronary artery
disease, arrhythmias, and
hypertension), metabolic
and endocrine disorders
(such as obesity and
growth alterations),
neurological diseases (pain,
cognitive changes, epilepsy,
attention deficit, and
stroke), gastrointestinal
diseases (cases of reflux),
psychiatric disorders
(bipolar affective disorder,
depression, and anxiety),
and urological diseases
(nocturia), among others.
The evolution of knowledge
in this area has raised
Sleep Medicine to the
status of a field of study in
Brazil, which comprises a
wide interface between
internal medicine (and its
various specialties) and
neuroscience. Nowadays in
Brazil, there are certified
specialists in Sleep
Medicine.
Symptoms
Sleep disorders vary from
extremely benign and
common, such as
temporary difficulty in
getting a good night's sleep
before situations of
excessive stress (acute
insomnia), to more
complex situations such as
severe sleep apnea with
cardiovascular and
metabolic impact, among
other things.
The main symptoms
related to sleep disorders
are excessive sleepiness or
fatigue during the day
and/or excessive
wakefulness or alertness at
night.
Other abnormal
manifestations involve
atypical behaviors during
the sleep period such as
parasomnias (sleepwalking,
confusional arousal, and
night terrors) or other
abnormal behaviors during
or close to sleep time. In
addition, sleep disorders
should always be
considered as aggravating
factors in situations of
illnesses of another nature.
Diagnosis
In addition to observations
from relatives of our
behavior as we sleep, there
is polysomnography, which
analyzes the patient while
he or she sleeps.
A night of sleep monitored
by electrodes and sensors
in a specialized laboratory
is the way to see what the
problem is. The test
monitors the movements of
the eyes and legs, the
electrical activity of the
brain, the breathing, and
the blood oxygen content,
among other things.
Einstein has a clinical staff
with certified specialists in
Sleep Medicine and two
modern polysomnography
laboratories (Morumbi and
Vila Mariana Units), in
addition to offering
polysomnography at home.
In addition, there is an
infrastructure of skilled
professionals, as well as an
advanced diagnostic center
where the
polysomnography tests are
applied.
Alzheimer's disease and
other dementias
Alzheimer's is a
degenerative disease whose
main symptom is the loss of
memory. This condition
affects the brain functions,
which can cause time
confusion and personality
changes. This impairs
everyday activities such as
going to work or keeping in
touch with relatives and
friends. At a more
advanced stage, patients
face physical limitations in
the ability to walk and even
to swallow.
Center of Excellence in
Memory
At Einstein, Alzheimer's
and other diseases related
to memory are treated at
the Center of Excellence in
Memory (NEMO). This
Center was created in
order to provide
professional care for a
growing demand. In Brazil,
healthcare experts estimate
that approximately 1
million people suffer from
the disease.
NEMO has a team of
highly specialized
professionals who, through
high technology techniques,
seek the earliest possible
diagnosis of the disease and
the appropriate treatment
to ensure a better quality of
life for patients and their
families.
Contact: +55 (11) 2151-
1100 (Call Center –
Rehabilitation)
Business Hours:
From 7 AM to 7 PM,
Monday through Saturday
– except on Wednesdays –
from 12 to 4 PM
Location: Medical Office
307, 3rd Floor, Wing A1
Services offered by
NEMO:
1. Computerized Memory
Evaluation
Clinical evaluation with a
neurologist done by means
of a computerized test that
assists in the diagnosis of
memory disorders and
dementia. This tool
evaluates executive
function and mental
control, language / symbol
fluency, and memory.
Created in the United
States and subsequently
adapted and validated for
Brazil, the test is done on
instruments with a touch
screen. This makes it easier
for people who are not
accustomed to using
computers.
2. Clinical evaluation with
a specialized doctor
Medical consultation with a
specialized neurologist
To schedule a visit:
Morumbi Unit: Call Center
– Rehabilitation: +55 (11)
2151-1100, from 7 AM to 7
PM Monday through
Saturday.
For more information,
please call +55 (11) 2151-
5094 or +55 (11) 2151-3555
from Monday to Friday, 8
AM to 6 PM BRT (Brasília
Time)
Or contact us by e-mail:
Neuro-.einstein@einstein.b
r.
3. Tap Test - Evaluation of
suspected Normal Pressure
Hydrocephalus (NPH)
This is a multidisciplinary
test to check for normal
pressure hydrocephalus
syndrome, in which the
patient presents gait
alterations, dementia, and
urinary incontinence,
which is one of the causes
of dementia. With proper
diagnosis, the disease can
be treated and reversed,
even if only partially.
The Tap Test is conducted
in more than one stage:
1. Neuropsychological
Assessment and Gait
Evaluation at the Gait
Laboratory (LEME) of the
Hospital Albert Einstein
At the laboratory, the
gait/walk is analyzed by
means of a 3-dimensional
analysis system of the
movement, made up of ten
infrared cameras, two
force platforms, and a
dynamic surface
electromyography (EMG)
apparatus.
2. Collection of
Cerebrospinal Fluid and
Neuropsychological and
Gait Reassessment at the
LEME facilities