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patient survival
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M. Miligy1 · Sasagu Kurozumi1 ·
Ian O. Ellis1 · Nigel P. Mongan4,5 · Andrew R. Green1 · Emad A. Rakha1,3,6
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Figure 1. The MMP-9 pathway. In the rectangles, the main molecules and signaling pathways leading to

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Arrows symbolize directions of connections. Abbreviations: AKT, protein kinase B; AP, activator protein;

CXCL, CXC chemokine ligand; ECM, extracellular matrix; ERK, extracellular-signal-regulated kinase;

HIF, hypoxia-inducible factor; IL, interleukin; LDLRP, low-density lipoprotein receptor-related protein;

MAPK, mitogen-activated protein kinase; miR, microRNA; MMP, matrix metalloproteinase; NF-kB,

nuclear factor-kappa B; NO, nitric oxide; PI3K, phosphoinositide 3 kinase; Sp, specificity protein; TGF,

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ORIGINAL ARTICLE J Breast Cancer 2011 June; 14(2): 88-95
J Breast Cancer 2011 June; 14(2): 88-95 DOI: 10.4048/jbc.2011.14.2.88