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R - Epilepsy Powerpoint Presentation 23
R - Epilepsy Powerpoint Presentation 23
•These attacks are sometimes called fits or seizures. A single seizure may occur for
no known reason. Some seizures are caused by a pathologic condition of the brain,
such as a tumor. In this case, once the underlying problem is treated, the patient is
often asymptomatic.
•Epilepsy is due to disturbance in the electrical activity of the brain that may result
in a change in level of consciousness (LOC), motor or sensory ability, and/or
behavior.
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SCIENCE & TECHNOLOGY
Def. cont
• Epilepsy Is caused by a transient, excessive and abnormal discharge of nerve
cells.
• The abnormal discharge may involve a small part of brain only ( partial or focal
seizure) or much more extensive area in both hemispheres (generalized
seizures).
• It can start at any age, In majority of the cases, it starts in childhood and
adolescence
• Tumors more likely after 40 years
• Those who suffer from Head trauma, CNS infections may occur at any age.
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CAUSES SCIENCE & TECHNOLOGY
2. Secondary epilepsy:-
- Intracranial Tumor
-Cerebro -vascular disease
-Arteriovenous malformation
-Trauma ( birth injury, depressed fracture, penetrating wound)
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CAUSES SCIENCE & TECHNOLOGY
• The most common causes of seizure disorder during the fist 6 months of life are severe
birth injury, congenital defects involving the central nervous system
(CNS), infections, and inborn errors of metabolism.
• In people between 2 and 20 years of age, the primary causes are birth
injury, infection, trauma, and genetic factors.
• In individuals between 20 and 30 years of age, seizure disorder usually occurs
as the result of structural lesions, such as trauma, brain tumors, or vascular disease.
• After 50 years of age, the primary causes of seizure disorders are stroke and metastatic
brain tumors. However, nearly 30% of all epilepsy cases are idiopathic, called
idiopathic generalized epilepsy (IGE), meaning they are not attributable to a specific
cause
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CAUSES CONT. & TECHNOLOGY
Prodromal
• The attack or fit occurs suddenly at any place or time.
• The patient falls down and loses awareness of his surroundings
• Convulsion proceeds as follows:
Aura
• Is a warning signal prior to onset of seizures e.g sensation of peculiar test or smell, spots
before eyes, dizziness and feeling of weakness.
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Phases cont SCIENCE & TECHNOLOGY
Epileptic cry:
Patient loses consciousness with an epileptic cry, it is caused by spasm of thoracic
and abdominal muscles expelling air through the glottis.
Tonic stage:
Patient falls to the ground with all his muscle in an increased tone with
rigidity. The skin become pale and cyanotic, the respiration ceases. Pupil dilated
and fixed. It lasts for 10-30 sec.
.
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Cont .,
• Clonic stage:
Is characterized by rhythmic, jerking
movements that follow the tonic
stage.it usually start at one place and
become generalized, including the
muscle of the face. There is frothing at
the mouth and
incontinence of urine and faeces.
Duration is approximately 1-5 min.
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TYPES OF GENERALISED SEIZURES
SCIENCE & TECHNOLOGY
• The tonic-clonic seizure
• The most common generalized seizure is the generalized tonic-clonic (formerly
known as grand mal) seizure. Tonic-clonic seizure is characterized by losing
consciousness and falling to the ground if the patient is upright, followed by
stiffening of the body (tonic phase) for 10 to 20 seconds and subsequent jerking
of the extremities (clonic phase) for another 30 to 40 seconds.
• Cyanosis, excessive salivation, tongue or cheek biting, and incontinence may
accompany the seizure. In the postictal phase the patient usually has muscle
soreness, is tired, and may sleep for several hours. Some patients may not feel
normal for several hours or days after a seizure. The patient has no memory of
the seizure.
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TYPES OF GENERALISED SEIZURES
SCIENCE & TECHNOLOGY
• Typical Absence Seizures. Or The absence seizure (formerly called petit mal)
usually occurs only in children and rarely continues beyond adolescence.
• This type of seizure may cease altogether as the child matures, or it may evolve
into another type of seizure.
• The typical clinical manifestation is a brief staring spell resembling “daydreaming”
that lasts only a few seconds, so it often goes unnoticed. When untreated, the
seizures may occur up to 100 times a day.
• The electroencephalogram (EEG) demonstrates a 3-Hz (cycles per second) spike-
and-wave pattern that is unique to this type of seizure. Hyperventilation and
flshing lights can precipitate absence seizures.
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TYPES OF GENERALISED SEIZURES
SCIENCE & TECHNOLOGY
• Atypical Absence Seizures is another type of generalized seizure which is
characterized by a staring spell accompanied by other signs and symptoms,
including brief warnings, peculiar behavior during the seizure, or confusion after
the seizure.
• It is longer lasting than a typical absence seizure and may be associated with loss
of postural tone.
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OTHER TYPESSCIENCE
OF GENERALISED SEIZURES
& TECHNOLOGY
Other generalized seizures are myoclonic, atonic, tonic, and clonic seizures.
• A myoclonic seizure is characterized by a sudden, excessive jerk of the body or
extremities. The jerk may be forceful enough to hurl the person to the ground.
These seizures are brief and may occur in clusters.
• An atonic (“drop attack”) seizure involves either a tonic episode or a paroxysmal
loss of muscle tone and begins suddenly with the person falling to the ground.
Consciousness usually returns by the time the person hits the ground, and
normal activity can be resumed immediately. Patients with this type of seizure
are at a great risk of head injury and often have to wear protective helmets.
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OTHER TYPESSCIENCE
OF GENERALISED SEIZURES
& TECHNOLOGY
• A tonic seizure involves a sudden onset of maintained increased tone in the
extensor muscles. These patients often fall.
• Clonic seizures begin with loss of consciousness and sudden loss of muscle tone,
followed by limb jerking that may or may not be symmetric
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PARTIAL SEIZURES
SCIENCE & TECHNOLOGY
• This is also called focal or local seizures and it begin in a part of one cerebral
hemisphere.
They are further subdivided into two main classes:
1. complex partial seizures (the person has a change or loss of consciousness)
• Primary or idiopathic epilepsy is not associated with any identifiable brain lesion or
other specific cause; however, genetic factors most likely play a role in its development.
• Secondary seizures result from an underlying brain lesion, most commonly a tumor or
trauma. They may also be caused by:
• • Metabolic disorders
• • Acute alcohol withdrawal
• • Electrolyte disturbances (e.g., hyperkalemia, water intoxication, hypoglycemia) • High
fever
• • Stroke
• • Head injury
• • Substance abuse
• • Heart disease
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Risk Factors SCIENCE & TECHNOLOGY
Seizures resulting from these problems are not considered epilepsy. Various risk
factors can trigger a seizure, such as
1. increased physical activity
2. emotional stress
3. excessive fatigue
4. alcohol or caffeine consumption,
5. certain foods or chemicals.
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Diagnosis and hx taking
SCIENCE & TECHNOLOGY
Diagnosis is based on the history and physical examination. A variety of diagnostic
tests are performed to rule out other causes of seizure activity and to confirm the
diagnosis of epilepsy. Typical diagnostic tests include an
• Electroencephalogram (EEG)
• Computed tomography (CT) scan
• MRI, or positron emission tomography (PET) scan.
• Magnetoencephalography.
• Transcranial doppler ultrasonography.
Laboratory studies are performed to identify metabolic or other disorders that may
cause or contribute to seizure activities
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NONSURGICAL MANAGEMENT.
• Removing or treating the underlying condition or cause of the seizure manages
secondary epilepsy and seizures that are not considered epileptic. In most cases,
primary epilepsy is successfully managed through drug therapy
• Most seizures can be completely or almost completely controlled through the
administration of antiepileptic drugs (AEDs), sometimes referred to as
anticonvulsants, for specific types of seizures.
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Drug MANAGEMENT. & TECHNOLOGY
• Drug therapy is the major component of management. The health care provider
introduces one antiepileptic drug (AED) at a time to achieve seizure control. If the
chosen drug is not effective, the dosage may be increased or another drug
introduced.
• At times, seizure control is achieved only through a combination of drugs. The
dosages are adjusted to achieve therapeutic blood levels without causing major
side effects.
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Drug MANAGEMENT. & TECHNOLOGY
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Drug MANAGEMENT.
SCIENCE & TECHNOLOGY
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Drug MANAGEMENT. & TECHNOLOGY
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MANAGEMENT.
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• Emphasize that drugs must not be stopped even if the seizures have stopped.
• Discontinuing these drugs can lead to the recurrence of seizures or the life-
threatening complication of status epilepticus
• A balanced diet, proper rest, and stress-reduction techniques usually minimize
the risk for breakthrough seizures. Encourage the patient to keep a seizure diary
to determine whether there are factors that tend to be associated with seizure
activity
• Patients who work in occupations in which a seizure might cause serious harm to
themselves or others (e.g., construction workers, operators of dangerous
equipment, pilots) may need other employment.
• They may need to decrease or modify strenuous or potentially dangerous
physical activity to avoid harm, although this varies with each person
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Seizure MANAGEMENT.& TECHNOLOGY
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SCIENCE
Seizure MANAGEMENT.& TECHNOLOGY
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SCIENCE
Seizure MANAGEMENT.& TECHNOLOGY
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What Triggers seizuresTECHNOLOGY
• Emotion stress
• Alcohol or alcohol withdrawal
• Infection
• Pyrexia
• Flickering light
• Noise
• Loud music
• Withdrawal of medication
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Status epilepticus Definitions
• Status epilepticus is a medical emergency and is a prolonged seizure lasting longer
than 5 minutes or repeated seizures over the course of 30
minutes.
• Is a state of continuous seizure activity or a condition in which seizures recur in rapid
succession without return to consciousness between seizures.
• It is a potential complication of all types of seizures and occurs with any type of
seizure
• Seizures lasting longer than 10 minutes can cause death! Common causes of status
epilepticus include:
• Sudden withdrawal from antiepileptic drugs
• Infection
• Acute alcohol or drug withdrawal
• Head trauma
• Cerebral edema
• Metabolic disturbances
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Epidemiology & TECHNOLOGY
• RBS
• FBC
• Blood culture
• Electrolytes, BUN, Creatinine, Na and Calcium (especially in malignancy).
• Liver function test
• Serum levels of antiepileptic drugs
• Urine levels of drugs
• Arterial blood gas analysis
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Treatment & TECHNOLOGY
• The goal of treatment in patients with epileptic seizures is to achieve a seizures free
status without adverse effects. This goal is accomplished by in more than 60% of
patients who require treatment with anticonvulsants.
• Nasopharyngeal airway placement is sufficient for some patients, particularly if the
seizures are stopped and the patient is awakening. For other patients, endotracheal
intubation is necessary. At times, rapid sequence induction, with neuromuscular
paralysis, is necessary.
• The principle of drug therapy is to begin with a single drug based on the patient’s
age and weight; type, frequency, and cause of seizure; and then increase the dosage
until seizures are controlled or toxic side effects occur.
• If seizure control is not achieved with a single drug, the drug dosage or timing of
administration may be changed or a second drug may be added. About one third of
patients require a combination regimen for adequate control
•
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Treatment cont.
• The drugs most commonly used are lorazepam (Ativan) and diazepam (Valium).
• Because these are short-acting drugs, their administration is followed with long
acting drugs such as phenytoin or phenobarbital
• Hyperthermia
• Acidosis
• Hypotension/hypertension
• Respiratory failure
• Rhabdomyolysis
• Aspiration
• Fractures
• Suicide ( sudden unexplained or unexpected death in epilepsy (SUDEP)
• ineffective coping methods
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SCIENCE &
NURSING DIAGNOSISTECHNOLOGY
Hinkle, J. Brunner, L.S. & Suddarth, D.S (2014). Textbook of medical surgical
nursing.13th ed. Lippincott, New York.
Burke, K.M; LeMone, P (2006). Medical-Surgical nursing care. 2nd ed. Upper
Saddle River, New Jersey: Pearson Education, Inc.
Le Hemone, & P. & Brake, K.M. (2000).Medical- surgical: critical thinking in
client care: New Jersey: Prentice Hall Inc.
Marion, J. (2001). Nursing diagnoses, outcomes and interventions. St Louis,
Mosby.
Mosby (2009) Mosby Pocket Dictionary of Medicine, Nursing and Health
Profession. 6th ed. St. Louis: Elsevier Health Sciences
Smeltzer, S., Bare, B., Hinkle, J., & Cheever, K. (2010). Brunner and Suddarth’s