AUTONOMIC NERVOUS SYSTEM

SYMPATHETIC (SNS)
Fight or flight Hypertention BP
Adrenergic Tacycardia HR
AntiCholinergic Tacypnea RR
Sympathomimetic Hyperthermia TEMP
Vasoconstrict Hyperglycemia CBG
Mydriasis (Pupilliay Dilation) EYES
Bronchodilation (beta agonist) LUNGS
Constipation INTESTINES
Retention BLADDER
Dry LACRIMATION
Dry SALAVATION

NUEROTRANSMITTERS
Monoamines=combination of increase Monoamine+ dec MAO=Mania decrease
Regulator=MAO
neurotransmitters/activates SNS Monoamine+Inc MAO=Depression inc+dec
Serotonin- happy hormone Monoamine and MAO=Bipolar
Nore-epinephrine-V/S
Dopamine-Muscle reg/reward sys

All anti depressant

All anti Psychotics
Parkinson drugs
RVOUS SYSTEM
PARASYMPATHETIC (PNS)
Hypotention (beta blocker) Rest and digest
Bradychardia Anti Adrinergic
Bradypnea Cholinergic
Hypothermia Parasympathomimetic
Hypoglycemia Vasodilate
miosis (Pulliary constriction)
Bronchoconstriction (beta blocker)
Diarrhea
Incontinence
Wet response
Wet response

SMITTERS
Acetylcholine=Activates PNS
Acetylcholine-Muscle
strenght,Memory,extra movement
Regulator=Cholinestarase
inc Acth+dec Cholinesterase=seizure, inc memory,
etra movement
dec Acth+ Inc Cholinesterase= MG

Mayasthenia gravis drugs

Seizure drugs, anti epileptic
Dx Description Hallmark sign Gen name B name
Alzheimers Brain area problem, dec acth Sundowning phenomenon Donepezil HCL Aricept
tacrine hydrochloride cognex
memantine
Meningitis Flouroquinolones
Azithromycin

ADHD Methylphenidate Ritalin

ADHD Methamphenamine Aderall
ADHD Atomoxetine Strattera

DEPRESSION Nortriptyline Pamelor

DEPRESSION Elavil
DEPRESSION Imipramine Tofranil
DEPRESSION Anafranil

DEPRESSION paroxetene Paxil

DEPRESSION Escitalopram Lexapro

DEPRESSION Fluoxetene Prozac

DEPRESSION Citalopram Celexa

DEPRESSION Trancyclopromine Parnate

DEPRESSION Izocarboxazid Marplan

DEPRESSION Phenelzine Nardil

ANXIETY Diazepam Valium
ANXIETY Lorazepam ativan
ANXIETY alfrazolam xanax
ANXIETY Midazolam versed

ANXIETY Chlordiazepoxide Librium

ANTI PSYCHOTIC Haloperidol Haldol
Chlorpromazine Thorazine/largactil
Clozepine
Resperidone
Olanzapine
seroquesl
aripiprazole

BIPOLAR Lithium Priadel,camcolit,lisconium

BIPOLAR
Class Notes/SE

Cholinesterase Inhibitors

effect Insomia. do not give at night. give before bfast and

CNS stimulant before lunch
CNS stimulant
Selective norepinephrine reuptake inhibitor

Tricyclic Anti depressants/TCA triptyline,pramine

Tricyclic Anti depressants/TCA triptyline,pramine
Tricyclic Anti depressants/TCA triptyline,pramine
Tricyclic Anti depressants/TCA triptyline,pramine

SSRI/Selective Serotonin Reuptake inhibitor xetine, Traline, Sexual dysfuction,weightgain, insomia

SSRI/Selective Serotonin Reuptake inhibitor xetine, Traline, Sexual dysfuction,weightgain, insomia

SSRI/Selective Serotonin Reuptake inhibitor xetine, Traline, Sexual dysfuction,weightgain, insomia

SSRI/Selective Serotonin Reuptake inhibitor xetine, Traline, Sexual dysfuction,weightgain, insomia

MAOI/Monoamine Oxidase Inhibitor

MAOI/Monoamine Oxidase Inhibitor

MAOI/Monoamine Oxidase Inhibitor

Benzodiazephines Antidote-Flumazenil
Benzodiazephines Antidote-Flumazenil
Benzodiazephines Antidote-Flumazenil
Benzodiazephines Good also for preop, Antidote flumazenil
Anxiety, insomia,alcohol widrawal, Antidote Flumazenil

Benzodiazephines
Typical/old gen/targets + symptoms regulates dopamine
Typical/old gen/targets + symptoms
Atypical/new gen/Targets +&- symptoms
Atypical/new gen/Targets +&- symptoms
Atypical/new gen/Targets +&- symptoms
Atypical/new gen/Targets +&- symptoms
Atypical/new gen/Targets +&- symptoms

Mood stabilizer Level-0.6 to 1.2

Increase urination
Toxicity effect
Hand-fine tremors
Increase OFI
Uu- Diarrhea, stomach flu
Maintain normal Na and h20 level
WOF
Bleeding

Tendinitis/pain in achilles area

"thro" ECG problems

For all Anti depressant drugs -Do not combine Anti deppresant drugs may lead
to serotonin syndrome, do not take with St John's wort herbal meds w/c lead to
serotonin syndrome,wash out period -2 to 6 weeks, and lag period 2 to 4 weeks
wof sudden icrease in mood may result in suicide

serotonin syndrome,avoid MAOIs,avoid grapefuirt, avoid st johns wort herbal

meds,Avoid alcohol
serotonin syndrome,avoid MAOIs,avoid grapefuirt, avoid st johns wort herbal
meds,Avoid alcohol
serotonin syndrome,avoid MAOIs,avoid grapefuirt, avoid st johns wort herbal
meds,Avoid alcohol
serotonin syndrome,avoid MAOIs,avoid grapefuirt, avoid st johns wort herbal
meds,Avoid alcohol
Serotonin is a chemical that the body produces naturally. It's
needed for the nerve cells and brain to function. But too
much serotonin causes signs and symptoms that can range
Wof Hypertensive crisis, avoid tyramine,serotonin synrome, may use from mild (shivering and diarrhea) to severe (muscle rigidity,
dandrolene sodium/succinylcholine as muscle relaxant to treat serotonin fever and seizures). Severe serotonin syndrome can cause
syndrome death if not treated.
Wof Hypertensive crisis, avoid tyramine,serotonin synrome, may use
dandrolene sodium/succinylcholine as muscle relaxant to treat serotonin
syndrome
Wof Hypertensive crisis, avoid tyramine,serotonin synrome, may use
dandrolene sodium/succinylcholine as muscle relaxant to treat serotonin
syndrome
wof respiratory depression
wof respiratory depression
wof respiratory depression
wof respiratory depression

wof respiratory depression

Wof agranulocytosis, Wof EPSE all Anti psychotics

Wof EPSE all Anti psychotics
Wof EPSE all Anti psychotics
Wof EPSE all Anti psychotics
Wof EPSE all Anti psychotics
Dx Description Hallmark sign Gen name B name Class Notes/SE
Infection control
Cdiff Metronidazole Flagyl Antibiotic dicoloration of urine is normal
Scabies/lice Permethrin Put below the neck
Scabies/lice Lindane Kwell 1%

vancomycin
WOF
Dx Descriptio Hallmark sign Gen name B name
Myasthenia Gravis Neostigmin
Parkinson's Disease levodopa+cabidopa Sinemet

Seizure Carbamazepine Tergetol

Seizure Phenytoin Dilantin

Migrane/Headaches Sumatriptan
Topiramate Topamax

Demyelination disorders Flexiril

Demyelination disorders Baclofen
Class Notes/SE
PNS

Anticonvulsants,anti seizure, anti epileptic maintenance drug-not prio

Anticonvulsants,anti seizure, anti epileptic Anti seizure, anti epileptic

S/E gingival hyperplasia-oral care
S/E brown color urine /expected
discuss alternate nonhormonal birth control

 stopping pain signals from being sent to the brain, and blocking the
Selective serotonin receptor agonists release of certain natural substances that cause pain,
For migrane and epilepsy

Muscle relaxants
WOF

A/E agranulocytosis =fever and sorethroat

10-20 mcg/Dl normal

A/E Infection and bleeding= pancytopenia or aplastic anemia-report
Terratogenic

Triggers extreme Temp,extreme flavor, extreme stress

Dx Description Hallmark sGen name B name Class
Hypothyroidsim/Myxedema Levothyroxine Sodium Synthroid
Hyperthyroidsm/Graves Prophylthiouracil Tapazole
Siadh dec diuresis Demeclocycline declomycin Tetracycline antibiotics

Spirolactone Aldactone K sparing

Triamterene hctz K sparing
Amiloride hcl K sparing

Furosemide Lasix k wasting

Bumetanide Bumex k wasting
Hydrochlorothiazide (HCTZ) k wasting
Mannitol k wasting

Diabetes Insupidus dami ihi Vasopressin DDAVP (deamino D- anti Diuretic Hormone
Desmopressin arginine vasopressin)

Addisons disease Prednisone/methylprednisolone Corticosteroids

Cushingssyndrome Prednisone/methylprednisolone Corticosteroids
Notes/SE WOF
Agranulocytosis
Agranulocytosis
antibiotic but diureticas SE

WOF ototoxicity

calcium sparring WOF renal stones

For Inc ICP/go through bool brain barrier

WOF fluid overload

Intranasal/synthetic vasopressin WOF fluid overload

supress immune system/anti inflamatory

supress immune system/anti inflamatory
Dx Description Hallmark sign Gen name B name

pril

captopril

enalapril
lisinopril

Sartan
valsartan
telmisartan
losartan

Olol
Metoprolol
Atenolol
Propanolol

depine
Amlodepine
Verapamil
Nifedipine
Diltiazem/cardizem

Statins

Atorvastatin Lipitor

symbastatin

Digoxin Lanoxin
Nitroglycerin Nitrostat
Class Notes/SE

ACE inhibitors For Hypertention

Angiotensin Converting
Enzyme An hour before meals (ACE)

Cough SE (report)
Edema(angio Edema/facial edema)

ARB
Angiotensin Receptive Blockers

BETA BLOCKERS for palpitations > 100HR

Check HR before giving the meds

CALCIUM CHANNEL
BLOCKERS For hypertention and ventricular rhytm problem (dysrythmia)
A Very Nice Dress S/E PNS
avoid grape friut Juice
For VD ventricular dysrhythmia

HMG co enzyme Inhibitor Anti cholesterolemia

statins except nystatin/mycostatin- antifungal for candida infection/ oral

Hydroxy methylglutaryl-CoA thrush / swish and swallow

MOA- Inc High densisty Lipoprotein(avocado,olive oil,tuna, macademia,

pistacio) and dec low density lipo protein (french fries, bacon)

Take it at night between 10 pm to 5 am (inc colesterol synthesis)

DOC for CHF MOA inc contactility= + inotropic

Cardiac Glycosides and dec heart rate= - conotropic
Check HR in 1 full minute check digoxin normal value 0.5-2
ng/dL
 route1: sublingual, expires after 6 months, can be given 3X 1 tab every 5
minutes) call EMT on the 1st dose, use dark bottles, do not combine with
Cardiac Glycosides DOC for Angina
sildenafil (Phosphodiesterase 2 inhibitor) f"il" vardefil, sildenafil-promotes
Tips
penile erection for 2 to
route2: patch- upper 4 hours/indicated
chest forpatch
or arm(deltoid), erectile
on dysfunction.if
12-16 hrs, patch> 4 off
hrs=Priapism
8hrs or at bedtime. Fold patch during disposal, rotate the site to avoid
tolerance
WOF

Wof angio edema and tall peak T wave/Hyperkalemia

Teratogenic

Wof angio edema and tall peak T wave/Hyperkalemia

A/E wheezing, contra indicated for lung problems

Bronchoconstriction
A/E depression

Wof for dizziness, fatal hypotension

do not combine with other hypertension drugs

Terratogenic

report liver and kidney check up (90 days treatment) if > 3 months report muscle weakness Rabdomylysis (destruction of fiber, release of Myoglobin, myoglobin irritates the kidney=Acute kidney injury)

Contraindicated with Vfib

Wof Toxicity Antidote- Digibind (Digoxin Immune Fab-Gen Name)

VANDA Visual disturbance Anorexia Nausea and vomitting Diarrhea Abdominal Pain
Dx Description Hallmark sign Gen name B name

WARFARIN
First generation
Lithum
Acetohexamide
Tetracycline (Dymelor)
Streptomycin Chlorpropamide
(Diabinese)
Valproic Acid Tolazamide (Tolinase)
Tolbutamide (Orinase)
Second
Rogain
generation
Thalidomides Glyburide (Micronase)
Isotretinoin Glipizide (Glucotrol)
Meglitinides
OHAS oxaprozin
Glimepiride(Daypro)
Repaglinide (Amaryl)
(Prandin)
etodolac (Lodine)
Nateglinide (Starlix)
indomethacin (Indocin)
Metformin
Pioglitazone(Glucophage)
(Actos)
naproxen (Naprosyn)
Rosiglitazone (Avandia)
Alpha-glucosidase
nabumetone (Relafen)
inhibitors (Cataflam)
Aspirin,Ibuprofen,naprox
diclofenac
NSAIDS en sodium
naproxen/esomeprazole
(Vimovo)
Doxycycline
Class Notes/SE WOF

Anticoagulants Antidote Vit K

Ace Inhibitors Angio edema/Inc tongue size
Mood stabilers for Bipolar
Antibiotics use straw to avoid staining the teeth Wof enamel hypoplasia
Antibiotics DOC for Kock's Disease (TB) A/E tinnitus
terratogenic, hepatotoxic, no to
Anti Seizure and bipolar electrocovulsive theraphy
Iodides Iodine Salt
Drug class for hair Risk for amelia/pocomelia
Anti
mostEmetic
widely used drugs for the treatment (birth defect)
For severe acne breakout
Sulfonylureas avoid
of typevit2 Adiabetes and appear to function
by stimulating insulin secretion
Meglitinines
Biguanides
Thiazolidinediones
Acarbose (Precose) high temperature or fever
Miglitol (Glycet) inflammation
OTC pain
Prescription
Antibiotics/tetracycline/ DOC
lyme disease
 build up of
Dx
Hyperemesis Description
inc HCGcells
in the Hallmark sGen name B name Class
Antiemetic/prokinetic
Hydatidiform cancer in
Gravidarum
mole/Gestational 2nd trimester Increase Metochlopramide
the uterus/ agents
Tropoblastic increase
common BP in in BP in the
pregnancy/ the
3rd 1st
trimester/ 1st
Disease trimester
presence of trimester Misoprostol Cytotec
protein in the Methotrexate
urine/ pre
Pre Eclampsia seizure

Magnesium
Eclampsia sulfate/ MgSO4
 medication used for stomach and esophageal
problems. It is commonly used to treat and prevent
nausea and vomiting, to help with emptying of the
Notes/SE
stomach in people with delayed stomach WOF
Not prio but
emptying, cantohelp
and helpwith
withmanagement
gastroesophageal
reflux disease

Induced abortion
may use teratogenic drugs

Prevent seizure/ parameters to remember= Wof for toxicity dec

monitor mg level (1.5 to 2.5) / dec DTR , dec RR,
DTR , dec RR, Oliguria, Dec BP/ antidote CA Oliguria, Dec BP/
gluconate antidote CA gluconate
Common Chemo drugs WOF

Vincristine Nuero toxic

Vinsblastine Nuero toxic

Cytosine Arabinoside (Ara-C) Conjunctivitis

5 Fluorouracil (5-FU) Oral thrush

Doxorubicin (adriamycin) Dysrhythmia

Cycloposphamide (cytoxan) Bladder toxic

Tomoxifen risk for DVT and heavy menses

Bleomycin Lung toxic

Busulfan Lung toxic

Methotrexate dec folic acid

risk for hypersensitivity
risk for pancytopenia (immuno compromised)
teratogenic
Antidote-Leucovirin

Filgastrim to inc WBC as a result of usperinfection from using chemo such as koch's disease amd oral trush
Dx DescriptionHallmark sGen name B name Class

Fluconazole
Disulfiram Antabuse
Notes/SE

For chronic alcoholism

WOF
Wof Liver problems, seizures, dec
WBC/Platelet count, heart rhythm changes,
dec adrenal gland function, severe allergic
reaction
Dx Description Hallmark sign Gen name

Aplastic Anemia/Pancytopenia Zidovudine

B name Class Notes/SE WOF
Antiviral but used
asImmunosuppresant
Dx DescriptionHallmark sGen name B name
Asthma Salbutamol
Albuterol
Sameterol

Asthma Theophylline
Aminophylline

Asthma Tiotropium
Ipratropium

Asthma Bethamethasone
Dexamethasone

Asthma Cromolyn

Asthma Montelukast
Zafirlukast

Koch's disease (TB)

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol
Streptomycin

Pneumonia Droplet Azithromycin

Clarithromycin
Erythromycin
Class
Bronchodilator, Sympatomimetic, Beta agonists

Bronchodilator, Methylxanthines

Anticholinergic

Coticosteroids

Mast cell stabilizer(mast cell releases histamine that causes asthma)

Leukotriene modifiers

Antibiotics

Macrolide antibiotics
Notes/SE WOF

emergency
Not for emergency

Emergency drugs, Normal 10-20 mcg/Dl

Emergency drugs, Normal 10-20 mcg/Dl

needs special inhaler, emergency

needs special inhaler

For inflamation, emergency Rinse mouth after administration

Rinse mouth after administration

For maintenace

For maintenace
For maintenace

RIPES
Discoloration, no to contact lens
1st to give, prophylaxis

Blurred vision
Tinnitus, ringing of the ear
Dx Descriptio Hallmark sGen name B name Class

Atropine Sulphate AntiCholinergic

acetylcholine

Carbamazepine Anti seizure, anti epileptic

valproic acid

Otherinhibitor
TNF Meds (tumor Necrosis
InflixiMAB Factor
AdalimuMAB

Epinephrine

Dabigatran Pradaxa Thrombin inhibitor

Clopidogrel Anti platelet

Codein Opiod
Notes/SE WOF

For Bradycardia-inc HR, reduce secretions

Extramovement and memory

For Seizure and bipolar terratogenic, hepatotoxic, no to electrocovulsive theraphy

DOC auto immune

DOC of anaphylaxis
can be given 3x
site :thigh part
can pass through layers of clothing
go to nearest ER for further evaluation

should always be in original container to prevent moisture contamination WOF for bleeding

as analgesic for moderate pain, anti tussive Wof constipation, nausea vomitting,dizziness
Wof Orthostatic hypotension
Dx DescriptionHallmark sGen name B name Class
Osteoporosis Alendronate Fosamax Biphosphonates
pagets/osteitis deformans

Risendronate

Gouty Arthritis Allopurinol

Colchine
Probenecid

TNF inhibitor (tumor

Rhematoid Arthritis InflixiMAB Necrosis Factor
AdalimuMAB

NSAIDS
Celecoxib Celebrex Cox 2 inhibitor

Corticosteroids

Osteoarthritis NSAID
Celecoxib Celebrex Cox 2 inhibitor
Glucosamine
Notes/SE WOF
Inhibit osteoclastic activity/ DOC for osteoporosis "nate"
Step1 Take 1 tab upon arising w/o meals w/ full glass of water
Step 2 remain upright for 30 mins to prevent esophageal irritation

DOC auto immune/ "nab"

for pain
for pain

"sone"

for pain
Herbal supplements, builds tendons,ligaments and cartilage
Dx DescriptionHallmark s Gen name B name Class

Interferon
Hepatitis alfa 2b

Inflamatory
Bowel disease Neomycin aminoglycosides
Includes Crohns
and Ulcerative
colitis
Notes/SE WOF
Interferons (IFNs) — the body's first line of antiviral defence — are
cytokines that are secreted by host cells in response to virus
infection. By inducing the expression of hundreds of IFN-stimulated
genes, several of which have antiviral functions, IFNs block virus
replication at many levels.

Stops growth of bacteria in the intestines