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8/19/22, 9:51 AM https://www.aafp.org/pubs/afp/issues/2007/0115/p211/jcr:content/root/aafp-article-primary-content-container/aafp_article_main_par/aafp_t… 8/19/22, 9:51 AM https://www.aafp.

org/pubs/afp/issues/2007/0115/p211/jcr:content/root/aafp-article-primary-content-container/aafp_article_main_par/aafp_t…

TABLE 1 Condition Rash presentation Pregnancy risk Treatment

Pregnancy-Specific Dermatologic Disorders Round, arched, or polycyclic patches


covered with small painful pustules in a
Systemic
Condition Rash presentation Pregnancy risk Treatment herpetiform pattern; most commonly
Reports of corticosteroids;
Impetigo appears on thighs and groin, but rash
Oral increased fetal antibiotics for
herpetiformis22,23 may coalesce and spread to trunk and
antihistamines morbidity secondarily
Intensely pruritic urticarial plaques and extremities; face, hands, and feet are not
and topical infected lesions
Pruritic urticarial papules with or without erythematous affected; mucous membranes may be
corticosteroids involved
papules and patches of papules and vesicles; rash first No identified
for pruritus;
plaques of appears on abdomen, often along striae adverse effects Topical
systemic
pregnancy17 and occasionally involves extremities; corticosteroids,
corticosteroids
face usually is not affected Erythematous follicular papules and topical benzoyl
for extreme Pruritic folliculitis No identified
symptoms sterile pustules on the abdomen, arms, peroxide
of pregnancy1 adverse effects
chest, and back (Benzac), or
Midpotency ultraviolet B
topical light therapy
Prurigo of Erythematous papules and nodules on No identified
1 corticosteroids
pregnancy the extensor surfaces of the extremities adverse effects
and oral Information from references 1 and 17 through 23.
antihistamines

Oral
antihistamines
Risk of premature
for mild
delivery,
Intrahepatic pruritus;
Excoriations from scratching; distribution meconium-stained
cholestasis of ursodeoxycholic
is nonspecific amniotic fluid,
pregnancy1,18,19 acid (ursodiol
intrauterine fetal
[Actigall]) for
demise
more severe
cases

Newborns may
Oral
have urticarial,
Pruritic papules, plaques, and vesicles antihistamines
vesicular, or bullous
evolving into generalized vesicles or and topical
lesions; risk of
Pemphigoid bullae; initial periumbilical lesions may corticosteroids
premature
gestationis20,21 generalize, although the face, scalp, and for mild cases;
deliveries
mucous membranes usually are not systemic oral
andnewborns who
affected corticosteroids
are small for
for severe cases
gestational age

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