EXERCISE NO.

06

1. When combined, BUN and creatinine are useful screening tests for assessing renal disease. Because they
are both nitrogenous metabolic byproducts. They are predominantly handled by glomerular filtration, with
little or no renal regulation or adaptation as renal function declines; they essentially mirror GFR. Though
they are not absolute indicators of renal function at any particular moment, they are valuable in assessing
development of the disease. In general, the ratio between creatinine and BUN is a 1:10 relationship.

2. A BUN blood test requires no specific preparation. You may eat regularly before the test if it is merely to
assess urea nitrogen levels in the blood. It should be noted, however, that if your blood sample will be used
for other tests, you may be required to fast for a specified period of time before the test.

3. A high BUN level usually indicates that your kidneys aren't performing properly. However, increased BUN
can also be caused by:
- Dehydration, that can occur as a result of not drinking enough fluids or for other causes.
- Obstruction of the urinary tract
- Heart failure or a recent heart attack
- Bleeding in the intestines
- Shock
- Severe burns
- Some medications, such as antibiotics
- A protein-rich diet