Antibiotic 1

Antibiotics 1 Dr.
Sameh
Doses
Doses
Doses
Doses
how to calculate the dose of infant or child doses
weight
is very important weight
weight
accurate
child infant Neonates

weight
age
one year age
2 9 age per months weight
6
2 9 6
7.5 15 /2
7.5 7
Page | 1
Antibiotics 1 Dr. Sameh
9
2 9 9
9 18 /2
9 8.5
exactly weight actual weight
percentile curves weight

percentile curves
11
2 9 11
10 20 / 2
10 9.5
3
2 9 3
6 12 / 2
6 5.5



2 9 age
One year infant very accurate
weight
8 2 age
4
8 2 X 4
16 8 8
3
14 8 2 X 3
Page | 2
8 2 X age in year weight
Weight
accurate dose
Obese Under weight
very bad dose
child
Obese Over weight under weight

calculating dose
age
adult antibiotics dose
adult maximum dose
30
weight
Doses
Syrup
concentration syrup
syrup forms
5 ml
5 ml concentration
5 125
5 250
5 200
5 Paracetamol 120 mg
5
Page | 3
dose
5 125 syrup
25
250
50
erythromycin 200
40
dose
12 8 3 4 5 7 6
dose
dose
syrup form
5 5
measurement
3.5
3.5
5
10 5 Measures
7.5
15
curve
Page | 4
30
30
measurements
antibiotics
dose
bacterial viral
antibiotics
antibiotics
viral infection diseases 90 %

respiratory upper respiratory diseases 90 %
viral infection otitis media sinusitis
3 viral
fever 
activity 
appetite 
fever
38 Low grade fever viral very high
fever
40 - 41 very high << viral
38
39.5 38.5 ) bacterial
activity
in between the fever is normal
viral
No need for antibiotics << viral Normal fever antipyretics fever
Page | 5
appetite
breast feeding infant suckling power
suckling power
suckling power suckling mechanism
viral disease
very poor suckling power bacterial infection
neonates
suckling power
Neonates sepsis
3
fever
activity
suckling power
bacterial viral
experience clinical
septic toxic
activity fever
septicemia signs of toxemia
antibiotics
48 follow up
bacterial bacterial 48 follow up
antibiotics
antibiotics
Page | 6
Antibiotics
antibiotics
against gram positive 

against gram negative 
gram positive
by the way
Penicillin antibiotics
antibiotics the first upper hand
penicillin resistance
Penicillin
penicillin sensitivity
very good penicillin response
Penicillin 3
crystalline penicillin Penicillin G 
100.000 50.000 dose
international unit / kg
international unit
vial
crystalline penicillin
100.000 50.000
international unit per kg per day
frequency
oral IM IV route of administration
penicillin
dose 100.000 50.000
frequency
must be divided
6
3
Page | 7
12 neonates
Not well developed kidney
Neonates 12
dose
International unit 100.000 50.000
vial
penicillin G
penicillin V 
Oral penicillin penicillin V
International unit per kg 100.000 50.000 dose
oral tablet oral syrup
syrup
300.000 international unit
5 300.000
400.000 international unit << Ospen

Must be given every 6 hours orally
tablet form
1.5 gram 1 gram
Benzathin penicillin 
27
27
3
rheumatic fever endemic
study
rheumatic sure serum level
Page | 8
3 suggest
1.2 600 200 1 27
200 27
rule
300 3 
600 6 3 
200 6 
Benzathin penicillin
antibiotics
penicillin is the best drug for gram positive bacteria
Beta hemolytic sterptococci
penicillin Organisms
beta hemolytic streptococci

endemic rheumatic fever
cardiology rheumatic fever eradication
Under diagnose Over diagnose
cardiology
penicillin
calculation
penicillin is unstable
Unstable
<<
dose
once dissolved must be given
Page | 9
accepted
penicillin
international unit 100 50 penicillin G

300 critical
meningitis
300 200
severe sepsis in neonates meningitis
crystalline penicillin
has no allergy
commercially used penicillin

procaine penicillin
sensitivity test
400 single daily dose << 4 sensitivity test
12 << 4
very good results

cefoperazone cefotax
chronic tonsillitis
chronic tonsillitis once

Procaine penicillin
400
single daily dose injection <<
<<
Half life
half life Prolongation procaine
Page | 10
procaine sensitivity
penicillin
sensitivity test
sensitivity test
course
sensitivity test 7
benzathin penicillin
Injection
Benzathin penicillin allergy
sensitivity test
Benzathin penicillin long acting penicillin
market
Depopen
Retarpen
most common used

Depopen
Retarpen
Depopen
pain
long acting penicillin
experience
distilled water Normal saline lidocain long acting penicillin
pain
Lidocain
cefotriaxone lidocain
Long acting penicillin
Retarpen Depopen
other products pain Depopen

Page | 11
2013 25 40 11
40 16
penicillin
ampicillin
Ampicillin
dose
antibiotics dose
100 50
50 - 100 mg / kg / day
50 - 100 mg / kg / day << dose of ampicillin
must be given every 8 hours

given every 6 hours
ampicillin
Market
ampicillin 
epicocillin 
epicocillin ampicillin 
125 << syrup

250 << syrup
0.5 << vial

1 << Vial
100 50 << dose
Mainly gram positive

200 150 << meningitis
10
100 50
severe Moderate mild
Mild 50
Page | 12
100 50
90 60
90 60
100 50 << accurate dose

90 60 << calculating dose
60 << mild
75 << moderate
90 << severe
3 divided doses
8
10
mild
600 60 X 10
8 3
200
per dose
syrup
250
50
12 600 / 50
12
8 200
8 4
Page | 13
125 antibiotics
25
8 200
8 8
severe 10
900 90 severe X 10
3
8 300
250
50
8 6
[ syrup 5 X ]
250 125 5 x ]
200 250 125 [ 200
severe 10
900 90 x 10
3
300
250 [ 5 X 300 ]
250 1500
6
Page | 14
mild 15
900 60 X 15
125
3 900
300
125 [ 5 X 300 ]
125 1500
8 12
severe 20
1800 90 X 20
3
8 600
250 [ 5 X 600 ]
250 3000
8 12
ampicillin
90 60
90 60
90 60
90 maximum dose
100
Amox ycillin
Most common drug used up till now
first drug of choice

amoxycillin
dose
90 60
3 divided doses
Page | 15
8
12 
12
90 60
3 divided doses
8
amoxycillin
amoxycillin 
E-mox 
Biomox 
Hiconcil 
Ibiamox 
Amoxil 
amoxycillin
Farconcil Amxoil E-mox 250 125

0.5 vial
0.25 E-mox
amoxycillin
90 60 dose
3 divided doses
Mild 15
900 60 X 15
3
8 300
250
250 5 X 300
250 1500
6
Page | 16
syrup << 400 200 market Ibiamox

200
40
400
80
mild 15
300
80
400 5 X 300
400 1500
3.75
4
Ibiamox 400 200

60
60
8
4
80 Biomox
8 5
5
400 Ibiamox
80
80
3 15
5
80 biomox
80 400 Ibiamox
5
4 3 8 400
Page | 17
severe 20
400 << Ibiamox
1800 90 X 20
3
8 600
400 ) 5 X 600
400 3000
7.5
7.5
8 7.5
7.5 measurements
10 5 measurement
8
Hiconcil drops
1 << antibiotics drops
amoxycillin 100
drops available Hiconicl

100
infant neonates
mild 3
180 60 X 3
Hiconcil drops
drops vial syrup drops
drops
1 1 <<
50 25 100
Page | 18
100
<<
100
small infant Neonates

3
Mild
180 60 X 3
3
8 60
0.6
8 2/3
young infancy neonates drops

4 3
6
50 dose
300 50 X 6
3
8 100
100
8
8
Moderate 2
150 75 X 2
3
8 50
8

2013 26 9
 22
Page | 19
is the best drug of choice << amoxycillin

Peritonsilliar abscess sinusitis otitis media Pharyngitis tonsillitis
High dose peritonsilliar abscess
chronic cervical lymphadenitis
Upper respiratory tract
amoxycillin
90 60 accurate dose
20 dose
20 mg / kg / dose
mild
30 mg / kg / dose
severe
60
3
20
90
3
30
75
Moderate
3
25
severe 13
390 30 X 13
Ibiamox
400
5
8
Page | 20
400 390
Mild 12
240 20 X 12
250 syrup
8
mild 10
200 20 X 10
8 200
250
4
severe 10
300 30 X 10
6
250
8
20 << Mild
25 << Moderate
30 << severe
Per dose
severe 20
600 30 X 20
400
400 Ibiamox
600
Page | 21
7.5
8
Ibiamox
400
mild 10
200 20 X 10
200 << Ibiamox
Amoxycillin + Calvulinic acid

Amoxycillin + Calvulinic Acid
amoxycillin calvulinic acid
amoxycillin resistant amoxycillin destruct << beta lactamase producing bacteria
calvulinic acid
amoxycillin action augmentation
amoxycillin
312 156 <<

5 syrup 156
31
62 312
156 312 << Magna-biotic

156 312 << E-moxclav
457 228.5
45 228.5
Page | 22
45
90 457
accurate dose
90 60
dose
90 60
amoxycillin 90 60
amxoycillin + calvulinic acid
over dose of amoxycillin
calvulinic acid side effects
Augmentin
the most expensive drug
228.5 457 << augmentin syrup

460 230 << Hibiotic
228 457 << Augmacillin

228 457 <<
457 228.5 << Megamox

228 457 <<
228
45
457
90
dose Augmentin vial vial available
Page | 23
90 60
must be given intravenously

market available
vial IV << 1200 600 Augmentin
never to be given intramuscular
9 never to be given orally
diarrhea vomiting << G.I.T. disturbance

side effects orally 9
in the neonates 30 20 << dose

90 60 << children
90 60 << infancy
in my experience
orally 9
can be given intravenously << Neonatal sepsis

8 3 divided doses 30 20 << dose
16 15
mild 11
dose 220 = 20 X 11
230
5 << 8 Hibiotic 230
8 augmentin 228.5
Mild 13
dose 260 20 X 13
9
270
90
3 270 / 90
Page | 24
457
228.5
45
457
90
460 230
Mild 18
360 20 X 18
4 360 / 90
90 457 << 90
457
severe 20
600 30 X 20
6.6666 600 /90
7
severe 8
20 Mild
400 20 X 20
4.44444 400 / 90
5
exactly 4.5
doses
Page | 25
Mild 14
280 20 X 14
6.2222 280 / 45
45
6
12 11.5
8 228.5
11.5
230 20 X 11.5
8 230
230
14
accurate dose 14
8 457 3.5
3.5
18
8 4
11.5 230
14 13
457
457 standard
14
8 3.5
15
8 3.5
16
8 4 3.5 hesitated
8 4 << 20 16
Page | 26
25 22 21 20
8 5
accurate accurate
Hiboitic 460 response
Hibiotic
Hibiotic 230
very expensive drug augmentin

High standard N
augmentin

Hibiotic 230
the most safest drug
230
45
accurate dose
rough idea
accurate

calculators
calculators dose
scientifically
you have your own calculator in your pocket
dose
calculator
dose
severe 20
Page | 27
600 30 X 20
9 630
630
630 / 90
7
mild 11.5
230 = 20 X 11.5
5.1 230 / 45
8 5
mild 15
300 = 20 X 15
312
312 5
Mild 8 under weight

160 20 X 8
156
8
Mild 18
360 20 X 18
4 360 / 90
90
457
mild 23
460 = 20 X 23
5
8
Page | 28
very accurate
calculated dose consultant
updated dose
Augmentin 
Hibiotic 460, 230 
Megamox (expensive) 
expensive 

augmacillin 
market 312 & 156 << Magna biotic E-moxclav E-moxclav 
amoxycillin calvulinic
side effects calvulinic acid

14
645
dose market
response
E-moxclav augmacillin Megamox Hibiotics Augmentin

magnabiotic
the most drug you have to be written
amoxycillin calvulinic amoxycillin

drugs
the first drug of choice in your prescription
Most common diseases

upper respiratory
Page | 29
Pneumonia 6
about 99 % << response IV 30 << dose
result
augmentin IV
8 30
orally
Augmentin
30 Hibiotic
90
results
Amoxycillin calvulinic << my prescription 90 %
drugs drug
amoxycillin calvulinic amoxycillin
amoxycillin calvulinic acid amoxycillin << the best
Ampicillin-Sulbactam
ampicillin
ampicillin destruct << beta lactamase producing bacteria
response
response
Sulbactam
250 <<
market
Unasyn 
Unictam 
Ampictam 
21
250
Page | 30
dose
50
100
100
can be given 12 hours or 8 hourly, but better to be given 8 hourly

8
12
8 It is very good
12
8
600 50 X 12
3 8
8 200 600 /3
8 4
12
8
4 12 /3
9
8
9
8
3 9/3
Page | 31
27
27
9 8
injection form dose

oral form
injection form Oral form antibiotics
Most specialist
injection form Dose
200 100
150 << optimum dose
150 << optimum dose
injection form
375 
2
750 
2
1500 
1500 750 375
dose
200 100
150 << results optimum
150
Unasyn 
Unictam 
 
Sulbin 
Injection ampictam 
gluteal region so heavy the best
injection Heavy
oral forms
Pharyngitis tonsillitis throat swab cultures
ampicillin sulbactam amoxycillin calvulinic positive
Page | 32
Amoxycillin calvulinic 
ampicillin sulbactam 
ampicillin sulbactam
hepato toxicity sulbactam
feed back
very good feed back
ampictam unictam Unasyn

Market available
unasyn ampictam Unictam Sulbin injection
ampicillin sulbactam amoxycillin calvulinic amoxycillin
9
history
antibiotics
amoxycillin
filing
tonsillits file
amoxycillin
improved revisit
antibiotics
tonsillits
Page | 33
amoxycillin
amoxycillin
mild 20 << dose amoxycillin
severe 30
20
don't shift
90 30 << high dose
otitis media
<< History
amoxycillin
otitis media
dose 30 amoxycillin
response
filing system
zero day
regular regular regular
suckling follicles follicular follicular tonsillits

bacterial weak power
amoxycillin
laryngitis pharyngitis tonsillitis toxic

ampicillin sulbactam amoxycillin calvulinic
high dose
dose 30
ampicillin sulbactam injection form

150
<< follow up
scientific 
Page | 34
step one, step two, step three and step four
amoxycillin
48 results antibiotics
48 serum level dose
72
amoxycillin
scientifically
dose
dose 20 dose
dose 30
72
chance one day more

dose
very accurate dose
calculated
choice
fever 3 90 %
activity
congestion throat
edema
tonsils minute follicles
for seven day
10 5 << course of antibiotics
14 <<
Page | 35
10 5
7 days << optimum
7 days infection
severe follicular tonsillitis

dental abscess
unicatm
8 8
dose
antibiotics
reassurance
8
regular for seven days
7 8 4
3
for seven days 3 8
2013 31 42 2
 48
Page | 36
7 days
documented
7
7 X 3 X 1
 7 X 3 X 1
Nurse
7 X 3 X 1
7 7 8 4 <<
objection
Page | 37
low
nurse
nurse
3 30 3
Page | 38
branch
twin
twin
treatment
10
black list
ampicillin sulbactam
first generation Cephalosporin drug
First generation Cephalosporin
Cephalosporins
Cephalosporin
Cephalosporins
third second first
fourth
Cephalexin
first generation cephalosporin
gram positive 80 %
Page | 39
gram negative 20 %
100 50 << dose << Cephalexin
90 60
accepted <<
Cephalexin
Keflex 
Ceporex 
Ospexin 
250 125
80 Keflex
dose
90 60
must be divided over 8 hourly

12
12 Keflex
125 & 250 << available

250 500
syrup
Mild 12
240 = 20 X 12
250
8
Mild 10
200 20 X 10
Page | 40
250
125
8
Ceporex Keflex
Ceporex
Cephalexin
Cephalexin
Cephalexin
24
cephalexin
pharyngitis follicular tonsillitis gram positive
Ceph radine
Cephradine
90 60 100 50 dose
100 25
25
90 60
the optimum dose
:
125 & 250 Cephradine 
80 market 125 & 250 Velosef 
125 & 250 << syrup form
Cephradine velosef
Vial forms
1 0.5
Page | 41
Cephalexin
injection << Keflex
available
group
Cephad roxil
can be given 12 hourly drugs
12
syrup << 500 500 250 125 << market Durisafe 

100 500
dose
50 25
Cephadroxil 100 25
100 25
50
optimum dose
20
1000 50 X 20
dose
500
syrup
500
12
16
800 50 X 16
12 400
4
Page | 42
500
12 4
14
700 50 X 14
12 350
3.5 500
7 250
12 7 250
12 3.5 500
injection
250
500
divided over two doses
12
market
Durisafe 
500 Biodoxil 
Ibidroxil 
Cephadrol 
Curisafe 
longicef 
Cephadroxil
Cephadroxil Cephradine ultrasef ultrasef
Cephadroxil ultrasef
Cephadroxil
Page | 43
gram positive upper respiratory
Urinary tract infection U.T.I. results
in high concentration in urine

very high renal excretion
Urinary tract infection results
urinary tract infection

first generation
injection shift << shift
emergency injection
injection
drug response injection
drugs injection
Durisafe Cefotax
third generation cephalosporin
mistake
antibiotics febrile
throat
severe infection
Oral toxic
12 1 E-mox vial
amoxycillin
Biomox
500 8 Biomox
Page | 44
injection choice
oral form injection availablity
unictam
unictam injection
injection Unasyn
Syrup

IV injection available
hospitalized difficult
response response
oral
injection Velosef
oral
amoxycillin
oral << amoxycillin
ampicllin sulbactam
oral
oral << injection chance

first generation
unasyn
Durisef
Durisef
Unasyn
Page | 45
Hiconcil
second generation cephalosporin

Second Generation Cephalosporin
Cefuroxime
Zinnat
oral dose
20
divided over two doses
Zinnat oral dose

20
two divided doses
125 << Zinnat Susp

250
injection form
100 50
vials << 750 250
Unictam
injection form oral
2 divided doses 20 << Oral
12 100 50 << injection

750 250 << available
two divided doses 20
Per dose 10
Page | 46
most used drug in second generation cephalosporin drug

Cefaclo r
Cefaclor
I like it very much 
gram positive Cefaclor

gram negative
anaerobic
Mycoplasma
cover
market Cefaclor
Price most expensive Ceclor 
Bacticlor 
Clorocef 
Cefaclor 
dose
40 30
must be given 8 hourly
3 30
Per dose 10
available
syrup << 250 125
Bacticlor 10
100 10 X 10
125
25
100
4
Page | 47
20
200 10 X 20
250
50
7.5
75 10 X 7.5
125
25
3

Zinnat
Zinnat 7.5
75 10 X 7.5
12
12 Zinnat
8 Cefaclor
second generation cephalosporin

second generation drug
I ll mention it
Page | 48
second generation
otitis media
first drug of choice
throat
throat
otitis media
Mild pharyngitis
severe Moderate
tonsillitis
otitis media Mild pharyngeo-tonsillitis
dose
8 30
chest infection severe tonsillitis otitis media
price
36 24
24 << 125
36 << 250
chest
Page | 49
tonsillitis
very good manufacturing
otitis media
chest
chest
chest action
Cefaclor Bacticlor
second generation
second generation
second line
tonsillitis Pharyngitis otitis media
first line
amoxycillin
amoxycillin amoxycillin
Cefaclor
chest infection
mycoplasma
second generation
the most prescription
Amoxycillin calvulinic acid 

ampicillin sulbactam 
Cefaclor Clorocef Bacticlor 
Page | 50
Price
12.5 << 125
14.5 << Cefaclor
22.5 << 250
12.5 << Price

14.5 << Cefaclor
22.5 250
antibiotics
2013 31 47
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Antibiotics 1 Dr.

child infant Neonates

percentile curves weight

8 2 X age in year weight

Obese Over weight under weight

viral infection diseases 90 %

39.5 38.5 ) bacterial

suckling power suckling mechanism

against gram positive 

400.000 international unit << Ospen

1.2 600 200 1 27

beta hemolytic streptococci

international unit 100 50 penicillin G

severe sepsis in neonates meningitis

commercially used penicillin

very good results

chronic tonsillitis once

Benzathin penicillin long acting penicillin

most common used

other products pain Depopen

must be given every 8 hours

125 << syrup

0.5 << vial

100 50 << dose

Mainly gram positive

100 50 << accurate dose

first drug of choice

Farconcil Amxoil E-mox 250 125

syrup << 400 200 market Ibiamox

Ibiamox 400 200

drops available Hiconicl

small infant Neonates

young infancy neonates drops

is the best drug of choice << amoxycillin

200 << Ibiamox

Amoxycillin + Calvulinic acid

312 156 <<

156 312 << Magna-biotic

amxoycillin + calvulinic acid

over dose of amoxycillin

calvulinic acid side effects

228.5 457 << augmentin syrup

228 457 << Augmacillin

457 228.5 << Megamox

dose Augmentin vial vial available

must be given intravenously

9 never to be given orally

diarrhea vomiting << G.I.T. disturbance

in the neonates 30 20 << dose

can be given intravenously << Neonatal sepsis

very expensive drug augmentin

Mild 8 under weight

amoxycillin calvulinic acid

side effects calvulinic acid

E-moxclav augmacillin Megamox Hibiotics Augmentin

amoxycillin calvulinic amoxycillin

Most common diseases