CHEMICAL CONTROL & COORDINATION
Chemical Control and Coordination NCERT Based Questions
Human Endocrine System -
Introduction
1. The organ system that helps regulate
the metabolic activities through
secretion of hormones is
(a) cardiovascular system
(b) endocrine system
(c) nervous system
(d) digestive system
2. The nervous and endocrine systems
interact to coordinate the functions of
all the body systems and help to
maintain
(a) homeostasis (b) reflex actions
(c) fight or flight response
(d) stress responses
3. Responses of the endocrine system are
_______ and _______ than the responses
of the nervous system.
(a) rapid, long-lasting
(b) rapid, briefer
(c) slower, long-lasting
(d) slower, briefer
4. Which of the following statements
correctly differentiate the endocrine and
nervous systems?
(a) The endocrine system regulates all
types of body cells.
(b) Nerve fibers innervate all the body
cell types.
(c) Endocrine system acts on specific
muscle cells only.
(d) The influence of the nervous system
is much broader.
(DPP)
5. Both neurotransmitters and hormones
(a) produce a slower response.
(b) bind to receptors on or in their
target cells.
(c) are transported by interstitial fluid.
(d) produce a rapid response.
6. Consider the following statements:
(A) Exocrine glands are the ductless
glands.
(B) Sweat glands and gastric glands
release their secretions directly into the
blood.
Select the correct option.
(a) Both (A) and (B) are true.
(b) (A) is true but (B) is false.
(c) Both (A) and (B) are false.
(d) (A) is false but (B) is true.
7. Which of the following gland types is
correctly matched with its examples?
(a) Adrenal gland: exocrine gland
(b) Placenta: exocrine gland
(c) Pancreas: endocrine gland only
(d) Thyroid gland: endocrine gland
8. Hormones are
(a) nutrients and intercellular
messengers
(b) nutrients and intracellular
messengers
(c) non-nutrients and intercellular
messengers
(d) non-nutrients and intracellular
messengers
 CHEMICAL CONTROL & COORDINATION (DPP)

9. Assertion: The nervous system 12. The hormones produced by

produces a delayed response that lasts hypothalamic nuclei
for a longer period.
(a) regulate the functions of the anterior
Reason: Neurotransmitters are released pituitary.
from postsynaptic neurons.
(b) regulate the functions of the
(a) Both Assertion and Reason are true posterior pituitary.
and Reason is correct explanation of
(c) regulate the functions of both
Assertion.
anterior and posterior pituitary.
(b) Both Assertion and Reason are true,
(d) inhibit the secretion of posterior
but Reason is not the correct
pituitary hormones.
explanation of Assertion.
13. Which of the following statements
(c) Assertion is true, but Reason is
about hypothalamic hormones is
false.
incorrect?
(d) Assertion is false, but Reason is
(a) Hypothalamic releasing hormones
true.
stimulate the secretion of anterior
Hypothalamus pituitary hormones.

(b) Hypothalamic releasing hormones

10. The small part of the brain that is
stimulate the secretion of posterior
present below the thalamus and serves
pituitary hormones.
as the main link between the nervous
(c) Hypothalamic inhibiting hormones
and endocrine system is
inhibit the secretion of anterior
(a) pons pituitary hormones.

(b) hypothalamus (d) Somatostatin is a hypothalamic

inhibitory hormone.
(c) brain stem
14. GnRH, a hypothalamic hormone,
(d) medulla oblongata needed in reproduction, acts on [NEET–
11. Consider the following events: 2017]

(A) Production of regulatory hormones (a) the posterior pituitary gland and
from neurosecretory cells. stimulates secretion of LH and relaxin.

(B) Hormones are secreted into the (b) the anterior pituitary gland and
portal system. stimulates secretion of LH and
oxytocin.
(C) Hormones move down the axons to
axon endings. (c) the anterior pituitary gland and
stimulates secretion of LH and FSH.
Arrange them in sequential order and
select the correct option. (d) the posterior pituitary gland and
stimulates secretion of oxytocin and
(a) A, B, C (b) A, C, B
FSH.
(c) B, C, A (d) C, A, B
 CHEMICAL CONTROL & COORDINATION (DPP)

15. Which of the following hypothalamic Select the correct option regarding the
hormones is incorrectly matched with same.
its function?
(a) I: Anterior pituitary that is
(a) TRH: Stimulates secretion of
composed of neural tissues.
thyrotropin
(b) PIH: suppresses the secretion of (b) I: Anterior pituitary that is
prolactin composed of epithelial tissues.

(c) GH-RH: stimulates secretion of (c) II: Posterior pituitary that is

growth hormone composed of epithelial tissues.
(d) CRH: stimulates the release of (d) II: Posterior pituitary that is
prolactin composed of connective tissues.
Pituitary Gland 19. In adults, adenohypophysis accounts
for 75% of the total weight of the gland
16. The pituitary gland is a pea-shaped and consists of
gland that lies in the hypophyseal fossa
(a) pars distalis
of
(b) pars tuberalis and pars intermedia
(a) sella turcica of the glenoid bone
(c) pars nervosa
(b) sella turcica of the sphenoid bone
(d) pars intermedia
(c) sella turcica of the parietal bone
20. Which of the following hormone is
(d) sella turcica of the frontal bone secreted by pars intermedia?
17. The pituitary gland is connected to the
(a) Prolactin
hypothalamus by
(a) infundibulum (b) bony cavity (b) Thyroid-stimulating hormone

(c) hyaline cartilage (d) elastic cartilage (c) Adrenocorticotrophic hormone

18. Following is the diagrammatic (d) Melanocyte stimulating hormone

representation of the pituitary gland
21. Which of the following statement is
and its connection with the
incorrect about the posterior pituitary?
hypothalamus.
(a) The posterior pituitary lobe is not a
true endocrine gland.

(b) It serves as a hormone storage

region.

(c) The posterior pituitary lobe and

infundibulum together make
neurohypophysis.

(d) Oxytocin and vasopressin hormones

are synthesized in the posterior
pituitary lobe.
 CHEMICAL CONTROL & COORDINATION (DPP)

22. Malfunctioning of endocrine gland 25. Hypersecretion of prolactin hormone in

deviates the body from homeostasis
and causes several disorders. Which of
the following disorder is correctly
matched with its respective endocrine
gland?
(a) Gigantism: Hyposecretion of growth
hormone
(b) Dwarfism: Hypersecretion of growth
hormone
(c) Acromegaly: Hypersecretion of
growth hormone
females causes inappropriate lactation
and absence of menstrual cycle. Based
on the given information, select the pair
of correct statements.
(A) Prolactin is required for milk
ejection from mammary glands.
(B) The blood level of prolactin is
increased just before menstruation.
(C) During pregnancy, prolactin
inhibiting hormone suppresses the
release of prolactin.

(d) Gigantism: Hypersecretion of (D) Sucking action of newborn inhibits

somatostatin the release of PIH.

23. Hypersecretion of growth hormone in (a) A and B (b) B and C

adults does not cause a further
(c) A and C (d) B and D
increase in height, because [NEET–
2017] 26. Select the option that correctly matches
the hormone with its source endocrine
(a) muscle fibers do not grow in size
gland and respective function/target
after birth.
organs. [Page: 333]
(b) growth hormone becomes inactive in
Hormone Endocrine Function/
adults. gland target organ
(c) epiphyseal plates close after (a) TSH Anterior All body
pituitary cells
adolescence. (b) ACTH Posterior Stimulates
pituitary secretion of
(d) bones lose their sensitivity to growth glucocortico
hormone in adults. ids from the
adrenal
24. A person is diagnosed with cortex
hypersecretion of growth hormone due (c) LH Anterior Triggers
to a pituitary tumor. Select the pituitary secretion of
incorrect statement about his medical androgens
condition. in males
(d) FSH Posterior Stimulates
(a) Hypersecretion of growth hormone pituitary the growth
would cause hyperglycemia. of ovarian
follicles
(b) There will be a reduced secretion of
insulin.
27. Which of the following set of hormones
(c) Insulin secretion would remain are called gonadotropins?
unaffected.
(a) GH and LH (b) LH and FSH
(d) Hypersecretion of growth hormone
results in a diabetogenic effect. (c) LH and ACTH (d) FSH and TSH
 CHEMICAL CONTROL & COORDINATION
28. The target cells/structures of FSH and
LH in human males are
(a) interstitial cells and sertoli cells
respectively.
(b) sertoli cells and interstitial cells
respectively.
(c) interstitial cells only.
(d) sertoli cells only.
29. LH is required for fertility in females
because
(a) it maintains corpus luteum.
(b) it induces ovulation.
(c) it stimulates the release of FSH from
corpus luteum.
(d) both (a) and (b)
30. Which of the following hormone is
incorrectly matched with its target
organ/cells?
(a) MSH: melanocytes
(b) Oxytocin: Smooth muscles
(c) Vasopressin: distal tubules of
kidneys
(d) ADH: Glomerulus
31. Diuresis refers to
(a) loss of water through urine
(b) reduced loss of water through urine
(c) process of urine formation in
nephrons
(d) contraction of muscles of the
urinary bladder
(DPP)
32. Diabetes insipidus is caused by
(a) hyposecretion of insulin by the
pancreas
(b) hyposecretion of ADH by the
posterior pituitary
(c) increased sensitivity of kidneys for
ADH
(d) hypersecretion of ADH by the
posterior pituitary
33. Assertion: TSH stimulates the thyroid
gland to secrete thyroid hormones.
Reason: The hormones of anterior
pituitary that regulate the secretions of
other endocrine glands are called tropic
hormones.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
34. Assertion: Hyposecretion of growth
hormone causes stunted growth in
infants.
Reason: Epiphyseal plates are closed
after the childbirth.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
 CHEMICAL CONTROL & COORDINATION (DPP)

35. Assertion: Hypersecretion of GH during 38. Which of the following hormone

childhood causes acromegaly. exhibits an anti-gonadotropic effect in
Reason: The growth hormone regulates humans?
the fluidelectrolyte balance of the body.
(a) ADH (b) Thyroxin
(a) Both Assertion and Reason are true
and Reason is correct explanation of (c) Melatonin (d) ACTH
Assertion.
Thyroid Gland
(b) Both Assertion and Reason are true,
but Reason is not the correct 39. Following is the diagrammatic view of
explanation of Assertion. the position of endocrine glands.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
36. Assertion: ADH secretion is stimulated
under the conditions of dehydration.
Reason: ADH prevents water loss from
the body by decreasing the urine
volume.
(a) Both Assertion and Reason are true
Select the option that correctly labels
and Reason is correct explanation of
Assertion. the glands and their respective
hormones.
(b) Both Assertion and Reason are true,
but Reason is not the correct (a) I - Thyroid gland - Thyroxine and
explanation of Assertion. TSH
(c) Assertion is true, but Reason is
false. (b) II - Parathyroid gland - PTH
(d) Assertion is false, but Reason is
(c) II - Thyroid gland - Thyroxine and
true.
calcitonin
Pineal Gland
(d) I - Parathyroid gland - PTH and
37. Which of the following set of functions
calcitonin
is not regulated by the hormone of the
pineal gland? [NCERT Exemplar]
40. The thyroid gland is composed of
(a) Diurnal rhythm and body
temperature (a) stromal tissues only

(b) Metabolism and pigmentation (b) follicles only

(c) Growth of bones and defense (c) stromal tissues and follicles
capability
(d) isthmus
(d) Diurnal rhythm and defense
capability
 CHEMICAL CONTROL & COORDINATION
41. Most of the T4 is converted into T3 in 45.
the target tissues because
(a) T4 is more active.
(b) T3 is more active.
(c) T4 has a shorter half-life.
(d) follicular cells cannot synthesize T3.
42. Thyroid hormones are required for
normal growth and development of
humans because
(a) thyroid hormones increase the basal
metabolic rate in most body tissues.
(b) thyroid hormones are regulated by
negative feedback systems.
(c) thyroid hormones contain iodine
atoms.
(d) thyroid hormones stimulate 46.
glycogen formation.
43. A group of tadpoles with no thyroxin
hormone production exhibited
disrupted metamorphosis. Which of the
following statement correctly describes
the role of thyroid hormones in
metamorphosis.
47.
(a) Thyroid hormones lower the blood
calcium levels.
(b) Thyroid hormones increase blood
calcium levels.
(c) Thyroid hormones lower the blood
phosphate levels.
(d) Thyroxin stimulates protein
synthesis.
44. Which of the following disorders of the
endocrine system is incorrectly
matched with its description?
(a) Hypothyroidism: Iodine deficiency
(b) Goitre: Enlarged thyroid gland
(c) Hyperthyroidism: Cretinism
(d) Exopthalmic goitre: Hyperthyroidism
(DPP)
Which of the given statement correctly
differentiates Myxedema from Graves’
disease?
(a) Hypothyroidism in adult ages causes
Graves’ disease.
(b) Graves’ disease is more common
among males than females.
(c) Myxedema causes swelling in facial
tissues due to the accumulation of
interstitial fluid.
(d) Myxedema is an auto-immune
disorder.
Graves’ disease is caused due to
(a) hyposecretion of the thyroid gland
(b) hypersecretion of the thyroid gland
(c) hyposecretion of the adrenal gland
(d) hypersecretion of the adrenal gland
Assertion: Thyroid hormones regulate
oxygen consumption and basal
metabolic rate of the body cells.
Reason: Thyroid hormones reduce the
number of active mitochondria in body
cells.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
 CHEMICAL CONTROL & COORDINATION (DPP)

Parathyroid Gland Thymus Gland

48. The physiological role of parathyroid 52. The endocrine gland that functions as a
gland does not include component of the lymphatic system is
(a) increased activity of osteoclasts (a) thyroid gland
(b) bone resorption
(b) thymus gland
(c) reduced loss of Ca2+ and Mg2+ ions
into urine (c) parathyroid gland

(d) reduced loss of HPO4 2- into the (d) pineal gland

urine
53. Which of the following endocrine gland
49. Which of the following hormones can is responsible for reduced immune
play a significant role in osteoporosis? responses in old ages?
(a) Aldosterone and Prolactin (a) Thyroid gland (b) Pineal gland
(b) Progesterone and Aldosterone
(c) Thymus gland (d) Pituitary gland
(c) Estrogen and Parathyroid hormone
Adrenal Gland
(d) Parathyroid hormone and Prolactin
50. Which of the following pairs of 54. Adrenal cortex and adrenal medulla
hormones have antagonistic effects? differ from each other in terms of
(a) T3 and T4 (a) histology (b) function
(b) ACTH and glucocorticoids (c) origin (d) all of these
(c) PTH and TCT (thyrocalcitonin)
55. The endocrine gland present at the top
(d) T3 and TSH of kidneys and involved in the fluid-
electrolyte balance of the body is
51. Assertion: Calcitonin and PTH exhibit
an antagonistic effect on blood levels of (a) adrenal gland
calcium ions.
(b) pineal gland
Reason: Insulin and glucagon exhibit
(c) parathyroid gland
antagonistic effects on the blood levels
of glucose. (d) pancreas
(a) Both Assertion and Reason are true 56. Which of the following categories of
and Reason is correct explanation of hormones is correctly matched with its
Assertion. examples?
(b) Both Assertion and Reason are true, (a) Catecholamines: adrenaline and
but Reason is not the correct noradrenaline
explanation of Assertion.
(b) Emergency hormones: adrenaline
(c) Assertion is true, but Reason is and insulin
false.
(c) Glucocorticoids: aldosterone
(d) Assertion is false, but Reason is
true. (d) Mineralocorticoids: cortisol
 CHEMICAL CONTROL & COORDINATION
57. Consider the following statements: 60.
(A) Some chemicals act as both
neurotransmitters and hormones.
(B) Norepinephrine is released as a
neurotransmitter by sympathetic
division.
(C) Norepinephrine is released as a
hormone by the thyroid gland.
(D) Norepinephrine is released as a
hormone by the parathyroid gland. 61.
Which of the two statements are
correct?
(a) A and B (b) A and C
(c) B and C (d) C and D
58. Secretion of hormones from adrenal 62.
medulla is controlled by
(a) parasympathetic nervous system
(b) pituitary gland
(c) sympathetic nervous system
(d) peripheral nervous system
59. The fight or flight response generated
by the release of hormones by adrenal
medulla includes
(a) dilation of pupils and increased
heart rate and blood pressure. 63.
(b) glycogenolysis and lipid synthesis.
(c) increased muscular movement of the
gastrointestinal tract.
(d) reduced blood glucose levels.
(DPP)
Which of the following hormones of the
adrenal cortex are correctly matched
with their source?
(a) Mineralocorticoids - Zona fasciculata
cells
(b) Glucocorticoids - Zona glomerulosa
cells
(c) Androgens - Zona glomerulosa cells
(d) Glucocorticoids - Zona fasciculata
cells
Glucocorticoids are involved in
(a) fluid electrolyte balance
(b) carbohydrate metabolism
(c) water reabsorption from kidneys
(d) regulation of blood glucose levels
Which of the following sets of
physiological functions correctly
describes the role of cortisol in the
human body?
(a) Anti-inflammatory response and
suppression of the immune response
(b) Breakdown of RBCs in spleen
(c) Upregulation of uptake of amino
acids
(d) Reabsorption of Na+ from kidneys
Target organ/structure of aldosterone
is
(a) renal calyces (b) renal tubules
(c) glomerulus
(d) Bowman’s capsule
 CHEMICAL CONTROL & COORDINATION
64. Assertion: Adrenal medullary hormones 68.
regulate the fluid-electrolyte balance of
the body.
Reason: Aldosterone is a glucocorticoid
that raises blood sodium levels.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct 69.
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
Pancreas
65. Which of the following pairs of
endocrine glands are composite glands?
(a) Pancreas and thymus gland
(b) Adrenal glands and thymus gland
(c) Pancreas and adrenal gland
(d) Adrenal gland and pineal gland
66. The cells that make about 70% of the
cells of the pancreatic islets serve to
secrete
(a) insulin (b) glucagon
(c) somatostatin 70.
(d) pancreatic polypeptide
67. Alpha and delta cells of pancreatic
islands are the source of
(a) glucagon and insulin respectively
(b) somatostatin and glucagon 71.
respectively
(c) glucagon and somatostatin
respectively
(d) insulin and glucagon respectively
(DPP)
Which of the following hormones is
correctly matched with its
description/effects?
(a) Hyperglycemic hormone: Glucagon
(b) Hypoglycemia: Glucagon
(c) Hypercalcemic hormone: Calcitonin
(d) Addison’s disease: Catecholamines.
Which of the given statements correctly
differentiates glycogenolysis from
glycogenesis?
(a) Glycogenolysis is the formation of
glycogen from glucose and is triggered
by glucagon.
(b) Glycogenolysis is a breakdown of
glycogen into glucose and is triggered
by insulin.
(c) Glycogenesis is the conversion of
glucose into glycogen and is stimulated
by insulin.
(d) Glycogenesis is the formation of
glucose from non-carbohydrate
substrates.
Diabetes mellitus is a disorder of
carbohydrate metabolism and is
characterised by
(a) polyuria (b) polydipsia
(c) polyphagia (d) all of these
The water-soluble fuels that are
normally exported by the liver but
overproduced during fasting or diabetes
mellitus when not treated are known as
(a) fatty acids (b) glucose
(c) ketone bodies (d) amino acids
 CHEMICAL CONTROL & COORDINATION (DPP)

72. Match the following hormones with the 75. Which of the following structures/cells
respective disease. [NEET–2019] of testes is incorrectly matched with its
functions? [NCERT Exemplar]
Column-I Column-II
(a) Seminiferous tubules -
(A) Insulin (1) Addison’s
Spermatogenesis
disease
(B) Thyroxin (2) Diabetes (b) Sustentacular cells - Secretion of
Insipidus FSH
(C) Corticoids (3) Acromegaly (c) Interstitial cells - Secretion of
(D) Growth (4) Goitre testosterone
hormone (d) Sertoli cells - Nourishment of
(5) Diabetes developing spermatogenic cells
mellitus
76. Testes serve as an endocrine gland.
Which of the given statement about
Select the correct option. testicular hormones is correct?
(a) LH from the posterior pituitary
(A) (B) (C) (D)
stimulates interstitial cells to secrete
(a) 5 1 2 3 testosterone.
(b) 2 4 3 1
(b) Testosterone suppresses the
(c) 5 4 1 3
secretion of LH and GnRH by the
(d) 2 4 1 3 positive feedback mechanism.
(c) FSH and testosterone stimulate the
Testes sustentacular cells to stimulate the
secretion of the androgen-binding
protein.
73. The ________ are the oval glands
present in the scrotum and serve to (d) Testosterone stimulates the process
secrete the hormones. of spermiogenesis.

(a) ovaries and androgen 77. The function of inhibin hormone is to

(a) inhibit the FSH secretion
(b) testes and testosterone
(b) inhibit the testosterone secretion
(c) pineal gland and melatonin
(c) inhibit spermiogenesis
(d) adrenal gland and cortisol
(d) stimulate spermatogenesis
74. Which of the following is not a function
78. Which of the given sets of organs
of testes?
represent the male accessory sex
(a) Spermatogenesis organs?

(b) Sperm production (a) Epididymis and testes

(b) Vas deferens and testes
(c) Testosterone secretion
(c) Seminal vesicles and prostate gland
(d) All of these
(d) Urethra and oviduct
 CHEMICAL CONTROL & COORDINATION (DPP)

79. The hormone responsible for the 83. Which of the following set of hormones
descent of testes into the scrotum is is known as female sex hormones?

(a) FSH (b) LH (a) FSH and LH

(c) testosterone (d) inhibin (b) Estrogen and progesterone

80. The function of testosterone in human (c) FSH and estrogen

males is/are
(d) LH and estrogen
(a) development of male secondary
84. Match the following structures in
sexual characters
Column-I with the correct description
(b) male sexual behaviour in Column-II.

(c) stimulation of protein breakdown Column-I Column-II

(d) both (a) and (b) (A) Ovarian (1) progesterone

follicles
81. Assertion: In human males, LH is
required for sperm production. (B) Corpus (2) LH

Reason: FSH and testosterone luteum

stimulate interstitial cells to secrete (C) Graafian (3) prolactin
androgen binding protein. follicle
(a) Both Assertion and Reason are true (D) Mammary (4) estrogen
and Reason is correct explanation of
glands
Assertion.

(b) Both Assertion and Reason are true,

but Reason is not the correct Select the correct option.
explanation of Assertion. (A) (B) (C) (D)
(c) Assertion is true, but Reason is (a) 4 3 2 1
false.
(b) 4 1 2 3
(d) Assertion is false, but Reason is (c) 3 4 2 1
true.
(d) 3 1 4 2
Ovary

82. Androgens are responsible for libido in 85. A temporary endocrine gland in the
both human males and females. The human body is [NEET–2017]
source of androgens in human females (a) pineal gland
is
(b) corpus cardiacum
(a) ovaries (b) oviducts
(c) corpus luteum
(c) corpus luteum (d) adrenal cortex (d) corpus allatum
 CHEMICAL CONTROL & COORDINATION
86. Which of the following statement is 90.
incorrect about the effects and
regulation of female sex hormones?
(a) Ovarian and uterine cycles are
under the regulation of Gonadotropin-
releasing hormone.
(b) In females, FSH triggers the 91.
development of follicles.
(c) Ovarian follicles secrete estrogen
under influence of FSH and LH.
(d) Estrogen from ovarian follicles is
converted into progesterone.
87. Which of the following hormones
regulates the formation of corpus
luteum and stimulates it to release
hormones?
92.
(a) FSH (b) LH
(c) Estrogen (d) Androgens
88. Which of the following hormones is not
secreted by corpus luteum?
(a) Estrogens (b) Progesterone
(c) Relaxin (d) LH 93.
89. Estrogens are the female sex hormone
secreted by ovarian follicles. Select the
incorrect statement about estrogens in
human females.
(a) Estrogen promotes the development
of secondary sexual characters in
females.
(b) Estrogen reduces blood cholesterol
levels.
(c) Estrogen inhibits the release of
GnRH from the hypothalamus.
(d) Estrogen is synthesized from
complex sugars.
(DPP)
Which of the following hormone is
synergistic to human growth hormone?
(a) Estrogen (b) Progesterone
(c) Inhibin
(d) Androgen binding protein
Cholesterol deposition in arteries
causes coronary artery diseases.
Women before menopause under the
age of 50 are least likely to develop the
disease as compared to men of the
same age. Which of the following
hormone is responsible for this
difference?
(a) Progesterone (b) Estrogen
(c) FSH (d) LH
The hormone responsible to prepare
and maintain endometrium for
implantation of a fertilized ovum is:
(a) FSH (b) LH
(c) Progesterone (d) Inhibin
Assertion: Corpus luteum is a
temporary endocrine gland.
Reason: Corpus luteum secretes female
sex hormones.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
 CHEMICAL CONTROL & COORDINATION (DPP)

Hormones of Heart, Kidney and
Gastrointestinal Tract
94. The atrial natriuretic factor is one of the
hormones that are not secreted from
endocrine glands. Which of the given
statements is correct about the atrial
natriuretic factor?
(a) The atrial natriuretic factor is
secreted by walls of the atrium of the
heart.
(b) The atrial natriuretic factor is also
known as vasopressin.
(c) The function of the atrial natriuretic
factor is to regulate water levels of
urine.
96. A patient with kidney failure was put
on dialysis. A routine blood test of the
patient to diagnose the possible cause
of weakness and fatigue showed a
reduced count of blood cells. Which of
the given hormones/factor may be
responsible for anaemia in the patient
of kidney failure?
(a) Increased blood sodium level
(b) Growth hormone
(c) Erythropoietin
(d) Atrial natriuretic factor
97. Which of the following hormones are
secreted from kidneys?
(a) Erythropoietin and calcitonin
(b) Erythropoietin and calcitriol

(d) Atrial natriuretic factor promotes the (c) Calcitriol and calcitonin
reabsorption of sodium. (d) Erythropoietin only
95. Match the hormones in Column-I with 98. Which of the following hormones of the
their functions in Column-II. gastrointestinal tract is wrongly
matched with its function?
Column-I Column-II
(A) Progesterone (1) Inhibits Column-I Column-II
uterine (A) Gastrin (1) Inhibition
of gastric
contraction secretions
(B) Atrial (2) Formation (B) Gastric (2) Stimulates
natriuretic of RBCs inhibitory secretion of
factor peptide (GIP) pancreatic
(C) Erythropoietin (3) Formation juice and
of alveoli in bile juice
mammary (C) Secretin (3) Secretion of
glands gastric
juice
(D) Relaxin (4) Lowers
blood (D) Cholecystokinin (4) Stimulates
secretion of
pressure pancreatic
juice
Select the correct option.
Select the correct option.
(A) (B) (C) (D)
(a) 4 3 2 1 (A) (B) (C) (D)
(b) 4 1 2 3 (a) 3 1 4 2
(b) 2 1 4 3
(c) 3 4 2 1
(c) 3 4 2 1
(d) 2 1 4 3 (d) 2 3 4 1
 CHEMICAL CONTROL & COORDINATION
99. Identify the hormone with its correct
matching of source and function.
(a) Oxytocin - posterior pituitary,
growth, and maintenance of mammary
glands.
(b) Melatonin - pineal gland, regulates
the normal rhythm of the sleep-wake
cycle.
(c) Progesterone - corpus luteum,
stimulation of growth and activities of
female secondary sex organs.
(d) Atrial natriuretic factor - ventricular
wall, increases the blood pressure.
100. Assertion: Hormones are also secreted
by tissues that are not the endocrine
glands.
Reason: Kidneys secrete the hormone
atrial natriuretic factor.
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
101. Assertion: Duodenum serves endocrine
function and secretes secretin
hormone.
Reason: Gastrin hormone from the
mucosa of the stomach stimulates the
secretion of gastric glands.
(DPP)
(a) Both Assertion and Reason are true
and Reason is correct explanation of
Assertion.
(b) Both Assertion and Reason are true,
but Reason is not the correct
explanation of Assertion.
(c) Assertion is true, but Reason is
false.
(d) Assertion is false, but Reason is
true.
Mechanism of Hormone Action
102. Most of the hormones reach all the
tissues but affect only target tissues
that have
(a) hormone receptors
(b) cell membrane proteins
(c) membrane phospholipids
(d) signaling molecules
103. Drugs that induce abortion prevent the
preparation of uterine endometrium
under influence of progesterone by
(a) preventing fertilisation
(b) blocking the progesterone receptors
(c) blocking the alveoli development in
mammary glands
(d) both (a) and (b)
104. Which of the given statements is
incorrect about the physiological effects
of hormones on their target tissues?
(a) A hormone may affect the
permeability of the cell membrane by
altering opening/closing of channels.
(b) Some hormones stimulate anabolic
pathways such as protein synthesis.
(c) A hormone may affect its target
tissue by altering the activity of
enzymes.
(d) Hormones do not affect the secretory
functions of the target tissues.
 CHEMICAL CONTROL & COORDINATION (DPP)

105. Which of the following category of 110. T3 and T4 hormones of the thyroid
hormones is incorrectly matched with gland are derived from
its examples?
(a) alanine (b) phenylalanine
(a) Protein hormone: Insulin
(c) tyrosine (d) glutamic acid
(b) Steroids: Cortisol
111. Which of the given hormones is
(c) Iodothyronines: Thyroid hormones incorrectly matched with its source
amino acid?
(d) Amino-acid derivatives: Oxytocin
(a) Serotonin: Tryptophan
106. Which of the following categories of the
hormones is water-insoluble? (b) Histamine: Histidine

(a) Eicosanoids (c) Epinephrine: Tyrosine

(b) Peptide hormones (d) Melatonin: Alanine

(c) Amines 112. The amino acid tryptophan is the

precursor for the synthesis of
(d) Steroid hormones
(a) estrogen and progesterone
107. Which of the given hormones is not a
steroid hormone? (b) cortisol and cortisone

(a) Aldosterone (b) Cortisol (c) melatonin and serotonin

(c) Serotonin (d) Androgens (d) thyroxin and triiodothyronine

108. Insulin and glucagon are water-soluble
______ hormones while melatonin is a
______
(a) peptide; amino acid derivative
(b) amino acid derivative; peptide
113. Which of the following statement
correctly differentiate the transport of
water-soluble and lipid soluble
hormones in blood?
(a) Most of the lipid-soluble hormones
are bound to transport proteins.

(c) peptide, peptide (b) Most of the water-soluble hormones

(d) steroid, peptide
109. Which of the given sets of endocrine
gland secrete/ release only water-
soluble hormones?
(a) Pancreas and thyroid gland
(b) Parathyroid gland and pineal gland
are bound to transport proteins.
(c) Transport proteins enhance the rate
of hormone loss in urine
(d) Transport proteins are synthesized
in muscles.
114. Receptors for protein hormones are
mostly present at/in

(c) Adrenal gland and thyroid gland (a) nucleus (b) nuclear envelop

(d) Parathyroid gland and pancreas (c) cell surface (d) cytoplasm
 CHEMICAL CONTROL & COORDINATION (DPP)

115. Which of the given statement is correct 118. Following is the diagrammatic
about the mechanism of water soluble representation of the mechanism of
hormones? action of a steroid hormone. Which of
(a) Hormones bind to their cytoplasmic the given options correctly describes
receptors present in the target cells. the labeled events?
(b) The hormone-receptor complex
alters the gene expression.
(c) Hormones serve as the first
messenger and cause the production of
a second messenger.
(d) The newly formed proteins produce
a physiological response.
116. Which of the following molecules serve
as the second messenger in the
mechanism of action of a protein
hormone?
(a) T3 (b) cAMP (a) I-Hormone, II-second messenger
(c) T4 (d) protein kinases (b) I-Hormone, III-nucleus
117. Following is the diagrammatic (c) II-Hormone-receptor complex, IV-
representation of the mechanism of DNA
action of a protein hormone. Which of
the given options correctly describes (d) II-Second messenger, IV-mRNA
the labeled events?
119. Assertion: Aldosterone can diffuse freely
through the lipid bilayer.

Reason: Steroid hormones are lipid-

soluble.

(a) Both Assertion and Reason are true

and Reason is correct explanation of
Assertion.

(b) Both Assertion and Reason are true,

but Reason is not the correct
(a) I-hormone receptor explanation of Assertion.
(b) II-hormone
(c) Assertion is true, but Reason is
(c) III-second messenger false.
(d) IV-physiological response
(d) Assertion is false, but Reason is
true.
 CHEMICAL CONTROL & COORDINATION (DPP)

120. Assertion: Receptors for steroid

hormones are present at the cell
surface.

Reason: Receptors for protein hormones

are present in the nucleus.

(a) Both Assertion and Reason are true

and Reason is correct explanation of
Assertion.

(b) Both Assertion and Reason are true,

but Reason is not the correct
explanation of Assertion.

(c) Assertion is true, but Reason is

false.

(d) Assertion is false, but Reason is

true.

121. Assertion: cAMP serves as the second

messenger for protein hormones.

Reason: Insulin is a protein hormone.

(a) Both Assertion and Reason are true

and Reason is correct explanation of
Assertion.

(b) Both Assertion and Reason are true,

but Reason is not the correct
explanation of Assertion.

(c) Assertion is true, but Reason is

false.

(d) Assertion is false, but Reason is

true.
 CHEMICAL CONTROL & COORDINATION (DPP)

ANSWER KEY : CHEMICAL CONTROL & COORDINATION

Q 01 02 03 04 05 06 07 08 09 10
Ans b a c a b c d c d b
Q 11 12 13 14 15 16 17 18 19 20
Ans b a b c d b a a a d
Q 21 22 23 24 25 26 27 28 29 30
Ans d c c c d c b b d d
Q 31 32 33 34 35 36 37 38 39 40
Ans a b a c d a c c b c
Q 41 42 43 44 45 46 47 48 49 50
Ans b a d c c b c d c c
Q 51 52 53 54 55 56 57 58 59 60
Ans b b c d a a a c a d
Q 61 62 63 64 65 66 67 68 69 70
Ans b b b d c a c a c d
Q 71 72 73 74 75 76 77 78 79 80
Ans c c b d b c a c c d
Q 81 82 83 84 85 86 87 88 89 90
Ans c d b b c d b d d a
Q 91 92 93 94 95 96 97 98 99 100
Ans b c a a c c b a b c
Q 101 102 103 104 105 106 107 108 109 110
Ans b a b d d d c a b c
Q 111 112 113 114 115 116 117 118 119 120
Ans d c a c c b c b a d
Q 121
Ans b