Ballesteros
only. Don’t inject or give orally
Generic Name: cetirizine
Indications:
 Seasonal Allergic Rhinitis
 Perennial allergic rhinitis
 Chronic urticaria
Side effects:
 somnolence
 fatigue
 Pharyngitis
 Dizziness
 dry mouth
Nursing Responsibilities:
 give without regard to meals
 Provide syrup form or chewable tablets
for pediatric use if needed.
 Report difficulty breathing,
hallucinations, tremors, loss of
coordination, irregular heartbeat.
 Provide skin care for urticaria.
Generic Name: Azelastine hydrochloride
Indications:
 pruritus from allergic conjunctivitis
 seasonal allergic rhinitis
 perennial allergic rhinitis (astepro only)
 vasomotor rhinitis (astelin only)
Side Effects:
CHS: Anxiety, dizziness, drowsiness, headache,
fatigue, sleep disorder
CV: Flushing, HTN, Tachycardia
GI: constipation, Diarrhea, abdominal Pain
GU: hematuria, Increased urinary frequency
Nursing Responsibilities:
- drug is for Ophthalmic or intranasal use
- don’t use ophthalmic form for irritation
caused by contactless
Generic Name: Hydroxyzine Hydrochloride
Indications:
 Anxiety
 Preoperative and post operative
adjunctive therapy for sedation
 Pruritus
 Nausea and Vomiting
Side Effects
CHS: drowsiness, dizziness, Fatigue
GI: dry mouth
Respiratory: Respiratory depression
Skin: Pain at IM injection site
Nursing Responsibilities:
 If patient takes other CHS drugs, watch
for oversedation
 Drug may rarely cause acute
generalized exanthematous pustulosis
(AGEP) a serious skin reaction involving
fever, pustules, and large areas of
edematous erythema. Discontinue at
first sign of rash, worsening of
preexisting skin reactions, or other signs
or symptoms of hypersensitivity. If sign
or symptoms suggest AGEP don’t
resume the therapy
 Elderly patients may be more sensitive
to adverse anticholinergic effects:
monitor these patient for dizziness,
excessive sedation, confusion, syncope
and dysuria
Generic Name: mizolastine
Indications:
 Allergic rhinitis,
  Urticaria
Side Effects:
CNS depression; QT prolongation.
Gastrointestinal disorders: Nausea, dry
mouth, abdominal pain, dyspepsia,
diarrhoea.
Nursing Consideration:
 Do not consume alcohol while
taking mizolastine
 May cause drowsiness and
dizziness
 Not recommended for children
under 12 years of age
 Hypersensitivity to Mizolastine is
a contraindication. In
addition, Mizolastine should not
be used if you have the following
conditions:
Generic Name: loratadine
Indication:
 Perennial and seasonal allergies.
 Vasomotor rhinitis
 Allergic conjunctivitis
 Mild uncomplicated urticaria and
angioedema
   antihistamine
Side effects:
CNS: confusion, drowsiness (rare), paradoxical
excitation. EENT: blurred vision. GI: dry
mouth, GI upset. Derm: photosensitivity,
rash. Metab: weight gain.
Nursing Consideration
 Advise patient about the risk of daytime
drowsiness, confusion, and decreased
attention and mental focus.
 Advise patient to avoid alcohol and
other CNS depressants because of the
increased risk of sedation and adverse
effects.
 Report difficulty breathing,
Hallucinations, Tremors, loss of
coordination, irregular Heart beat
Chlorpheniramine
Indications:
 Symptomatic relief of symptoms
associated with perennial and seasonal
allergic rhinitis, vasomotor Rhinitis, and
sedative effects
Side effects:
CHS: drowsiness, sedation, dizziness, disturbed
coordination
CV: hypotension, palpitations, bradycardia,
tachycardia
Nursing Considerations:
 Administer with food if GI upset occur
 Take as prescribed avoid excessive
dosage
 Avoid alcohol, serious sedation may
occur
 Avoid over the counter drugs, may
contains ingredients that could cause
serious reactions if taken with this
 Report difficulty breathing:
hallucination, tremors, loss of
coordination, unusual bleeding.