Service-Manual ThermoMixer-C F0.5 F1.5 F2.0 FP ThermoStat-C Eng PDF

al
ermoMixer
- English
manual
EN) C/F0.5/F1.5/F2.0/FP/ThermoStat C
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www.eppendorf.com/myeppendorf
Eppendorf ThermoMixer
C/F0.5/F1.5/F2.0/FP/ThermoStat C
Service manual - English
Copyright© 2016 by Eppendorf AG. All rights reserved, including graphics and images. No part of this
publication may be reproduced without the prior permission of the copyright owner.
Eppendorf ThermoMixer® and Eppendorf ThermoTop® are registered trademarks of Eppendorf AG,
Germany.
Eppendorf® and the Eppendorf logo are registered trademarks of Eppendorf AG, Germany.
Registered trademarks and protected trademarks are not marked in all cases with ® or ™ in this manual.
U.S. Design Patents are listed on www.eppendorf.com/ip.
5382 920.017-04/012016
Table of contents
Eppendorf ThermoMixer C/F0.5/F1.5/F2.0/FP/ThermoStat C 3
English (EN)
Table of contents
1 Operating instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
1.1 Using this manual . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
1.2 Danger symbols and danger levels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
1.2.1 Danger symbols. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
1.2.2 Danger levels. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
1.3 Symbols used . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
2 Product description . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.1 Device overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.2 Assemblies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.2.1 Chassis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.2.2 Upper part of housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
2.2.3 Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.2.4 PCB control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.2.5 PCB motor control. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.2.6 PCB temperature control. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.2.7 Heating/cooling plate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.2.8 SmartBlocks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.2.9 Thermoblock . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.2.10 Fan for cooling and for the electronic system. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
2.2.11 Switched-mode power supply. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
2.2.12 USB interface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
2.2.13 ThermoTop . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
3 Safety. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
3.1 User profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
3.2 Notes on liability . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
3.3 Maintenance and repair hazards. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
4 Operation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
5 Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
5.1 Error messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
5.2 Service functions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
5.2.1 Overview of service functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
5.2.2 Activating the service functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
5.2.3 Operating the service functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
5.2.4 SE 01 (error memory) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
5.2.5 SE 02 (operating times/runs) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
5.2.6 SE 03 (sensors) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
5.2.7 SE 04 (key test) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
5.2.8 SE 05 (motor) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
5.2.9 SE 06 (fan). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
5.2.10 SE 07 (memory reset) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Table of contents
4 Eppendorf ThermoMixer C/F0.5/F1.5/F2.0/FP/ThermoStat C
English (EN)
6 Disassembly/assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
6.1 Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
6.2 Separating the upper part of housing and the chassis (disassembling heating/cooling plate and
thermoblock)25
6.2.1 Eppendorf ThermoMixer C and Eppendorf ThermoStat C . . . . . . . . . . . . . . . . . . . . . . 25
6.2.2 Eppendorf ThermoMixer F0.5/F1.5/F2.0/FP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
6.3 Disassembly of upper part of housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
6.3.1 PCB control (incl. display). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
6.3.2 Switched-mode power supply, USB interface and fan for switched-mode power supply
31
6.3.3 Keypad and front clip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
6.3.4 Centering pins (including PCB TT power) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
6.4 Disassembly from the chassis Eppendorf ThermoMixer C and Eppendorf ThermoMixer Fxx . 33
6.4.1 Orbital plate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
6.4.2 Imbalance eccentric . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
6.4.3 Motor. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
6.4.4 PCB motor control. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37
6.4.5 Stabilizer links . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
6.4.6 Fan for cooling (Eppendorf ThermoMixer C only) . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
6.4.7 Chassis closing (Eppendorf ThermoMixer Fxx only) . . . . . . . . . . . . . . . . . . . . . . . . . . 39
6.5 Dismantling the Eppendorf ThermoStat C chassis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
6.5.1 PCB temperature control. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
6.5.2 Fan for cooling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
6.6 Device assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
7 Alignment/adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
7.1 Setting and adjusting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
7.1.1 Setting the electronics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
7.1.2 Temperature adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
7.1.3 Mechanical adjustment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
8 Software . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
8.1 Software update . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
8.2 Bootloader. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
9 Diagrams . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
9.1 Eppendorf ThermoMixer C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
9.2 Eppendorf ThermoStat C . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
9.3 Eppendorf ThermoMixer F0.5/F1.5/F2.0 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
9.4 Eppendorf ThermoMixer FP . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
Table of contents
English (EN)
10 Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
10.1 Cleaning, disinfection, decontamination. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
10.2 Shipping the device. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
10.3 Service and inspection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
10.3.1 Essential check . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
10.3.2 Advanced maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
10.3.3 Qualification services - operational qualification (OQ) . . . . . . . . . . . . . . . . . . . . . . . . . 54
10.4 Device inspection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
10.4.1 Temperature check . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
10.4.2 Speed check . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
10.4.3 Timer check. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
10.5 Electrical safety check. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
11 Technical data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
11.1 Power supply. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
11.2 Weight/dimensions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
11.3 Ambient conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
11.4 Tolerances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
11.4.1 Temperature accuracy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
11.4.2 Temperature homogeneity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
11.4.3 Speed. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
11.4.4 Time . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
12 Ordering information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
12.1 Figures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
12.2 Spare parts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
12.2.1 Housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
12.2.2 Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
12.2.3 Electronics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
12.2.4 Fan. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
12.2.5 Accessories/auxiliary aids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
12.2.6 SmartBlocks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
12.3 Spare parts proposals – initial equipment. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
13 Technical information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Table of contents
English (EN)
Operating instructions
English (EN)
1 Operating instructions
1.1 Using this manual
 Make sure that the service manual and the operating manual are available in the latest versions. To do
so, compare the version numbers. The latest versions of the manuals can be downloaded from
www.eppendorf-support.com and www.eppendorf.com.
 Read the service manual before commencing work on the device.
 Read the chapters "Installation" and "Operation" of the operating manual.
 Observe the safety instructions in the operating manual.
1.2 Danger symbols and danger levels
The safety precautions in these instructions have the following danger symbols and danger levels.
1.2.1 Danger symbols
Biological hazard Explosive substances
Electric shock Hot surface
Cuts Hazard point
Material damage
1.2.2 Danger levels
DANGER Will lead to severe injuries or death.

WARNING May lead to severe injuries or death.
CAUTION May lead to light to moderate injuries.
NOTICE May lead to material damage.
1.3 Symbols used
Depiction Meaning
1. Actions in the specified order
2.
 Actions without a specified order
• List
Text Display text or software text
Additional information
Operating instructions
English (EN)
Product description
English (EN)
2 Product description
2.1 Device overview
Product numbers, device names and abbreviations

• 5382: Eppendorf ThermoMixer C (TMC)
• 5383: Eppendorf ThermoStat C (TSC)
• 5384: Eppendorf ThermoMixer F1.5 (TMF1.5)
• 5385: Eppendorf ThermoMixer FP (TMFP)
Eppendorf ThermoMixer Fxx and TMFxx: abbreviation for Eppendorf ThermoMixer F0.5/
F1.5/F2.0/FP.
2.2 Assemblies
All devices consist of the following assemblies:

• Chassis
• Upper part of housing
• Drive, consisting of motor and stabilizer links
• PCB control
• PCB motor control (Eppendorf ThermoMixer C and Eppendorf ThermoMixer Fxx)
• PCB temperature control (Eppendorf ThermoStat C)
• Heating/cooling plate (Eppendorf ThermoMixer C and Eppendorf ThermoStat C)
• SmartBlocks (Eppendorf ThermoMixer C and Eppendorf ThermoStat C)
• Thermoblock (Eppendorf ThermoMixer Fxx)
• Fan for cooling (heat sink fan) and for the switched-mode power supply
• Switched-mode power supply
• USB interface
• ThermoTop
2.2.1 Chassis
All devices have the same metal chassis. It holds the drive and the fans (including the air duct) for cooling.
The Eppendorf ThermoStat C has an enlarged heat sink installed instead of the drive.
2.2.2 Upper part of housing
All devices have the same plastic upper part of housing. The device name is printed on an exchangeable
clip. The clip is inserted in the front of the housing. The upper part of housing and the clip are connected to
each other by the device-specific adhesive keypad.
The upper part of housing contains the PCB control, the mains input (switched-mode power supply), the
fan for the switched-mode power supply, the USB interface and the contact to the ThermoTop.
Product description
English (EN)
2.2.3 Drive
The rotary movement of the motor is translated onto a circular orbit via an eccentric. A counterweight
compensates the resulting imbalance and ensures the stability of the device. The weight of the accessories
and their load is held by two stabilizer links. The stabilizer links are mounted on both sides of the motor.
The motor is controlled using the PCB motor control. A Hall sensor in the motor detects the speed and
reports it to the PCB control for checking.
2.2.4 PCB control
The PCB control is the central control unit of the devices containing the firmware. All internal operating
modes are controlled and monitored here. The commands that are entered via the keypad are recorded and
forwarded to the corresponding assemblies (e.g., PCB motor control, PCB temperature control). All sensor
feedback signals are recorded and processed, e.g., speed and temperature. The firmware responds
independently to the values received and makes adjustments, if required.
The three thermal modules (heating foil, Peltier module, ThermoTop) are activated sequentially by a
multiplexer. In this way, each thermal module can be supplied with maximum power.
The PCB control also includes the display on which all information can be displayed that is relevant to the
operation.
The switched-mode power supply supplies the PCB control with 24V. The other voltages (5 V, 12 V, etc.)
are generated directly on the PCB control from the 24 V.
There are always two temperature sensors each. The two values that are reported back are constantly
compared with each other. If the deviation is too great, the unit concerned is switched off and an error
message appears on the display. The motor speed is monitored by a Hall sensor. If the deviation from the
set speed is too great, the motor switches off and a corresponding error message appears on the display. In
addition, the current flow to the heating and the motor is monitored constantly. If the maximum value is
exceeded, the corresponding unit is deactivated and a corresponding error message also appears on the
display. Fuses are used as a further safety measure, they interrupt the circuits irreversibly, if required (the
fuses cannot be replaced).
All devices have the same PCB control with the same firmware. The firmware recognizes the device model
via the connected keypad that is unique to the device.
2.2.5 PCB motor control
The PCB motor control controls the motor. The parameters for controlling the motor of the device model
are stored on the PCB motor control. The heat sink fan is connected to the PCB motor control.
2.2.6 PCB temperature control
The PCB temperature control is only used with the Eppendorf ThermoStat C. The two heat sink fans are
connected to the PCB temperature control.
Product description
English (EN)
2.2.7 Heating/cooling plate
The heating/cooling plate includes a heating foil for heating and a Peltier module for cooling. An integrated
Hall sensor checks whether a SmartBlock has been mounted. The range of the Hall sensor has been
restricted so that the device can only be started if the SmartBlock has been mounted correctly.
2.2.8 SmartBlocks
The SmartBlocks have been actively integrated in the temperature control process. The SmartBlocks
contain the temperature sensors for temperature control and a memory which includes all the values that
are relevant for controlling the temperature. Each SmartBlock is individually adjusted during manufacture.
The SmartBlocks communicate with the device in a non-contact manner, via an optical-inductive interface
which is located on the bottom (front right).
The respective maximum speed of the SmartBlock is also stored in the SmartBlock and communicated to
the device via the optical inductive interface.
Power for the sensors and the memory is also being supplied in a non-contact manner via the
optical-inductive interface.
The SmartBlock plates has a light barrier on the right-hand side which is used to detect the height of the
loading used. If it has been loaded too high, the maximum speed is reduced.
2.2.9 Thermoblock
The Eppendorf ThermoMixer Fxx thermoblocks are tempered with a heating foil. The temperature sensors
and a memory with the parameters that are relevant for temperature and speed control are integrated into
the heating foil of the thermoblocks. They are individually adjusted during manufacture.
The thermoblock of the Eppendorf ThermoMixer FP has a light barrier on the right-hand side which is used
to detect the height of the loading used. If it has been loaded too high, the maximum speed is reduced.
2.2.10 Fan for cooling and for the electronic system
Depending on the device model, up to three fans are used:
• Eppendorf ThermoMixer Fxx: A fan for the switched-mode power supply.

• Eppendorf ThermoMixer C: A fan for the switched-mode power supply and a fan for the block
temperature control (heatsink fan).
• Eppendorf ThermoStat C: A fan for the switched-mode power supply and two fans for the block
temperature control (heatsink fan).
The heatsink fans have a variable speed control which depends on the temperature of the heatsinks
(determined indirectly via the Peltier voltage) and the set target temperature. The fan for the
switched-mode power supply has a speed control which depends on the output (it is switched off < 50 W).
Product description
English (EN)
2.2.11 Switched-mode power supply
The devices are supplied with power via a switched-mode power supply which outputs the internal supply
voltage (24 V) to the PCB control.
2.2.12 USB interface
A USB interface is located at the rear. The firmware of the devices can be updated via this interface and an
external laptop/PC.
2.2.13 ThermoTop
The ThermoTop can be used with some SmartBlocks to prevent condensation. It holds a temperature which
is approx. 3 to 18 Kelvin above the set block temperature. Due to differences in height between some of the
SmartBlocks/thermoblocks the exact temperature depends on which SmartBlock/thermoblock is used. The
temperature is controlled via two integrated temperature sensors which communicate with the device via
an optical-inductive interface.
The heating foil is supplied with power via two centering pins on the upper part of the device housing. For
safety reasons, the current flow via the centering pins is only active when the ThermoTop has been
attached (however, a centering pin still has a variable potential!).
The centering pins and some magnets fix the ThermoTop at the rear. At the front, the ThermoTop is fixed
by two magnets.
Safety
English (EN)
3 Safety
3.1 User profile
The specialist entrusted with maintenance, repair or testing must meet the following prerequisites:
• Successful participation in service trainings with certification by Eppendorf AG for the product that is to
be maintained, repaired or tested.
• Qualification as a specialist with knowledge of the applicable local and international standards.
• Qualification to evaluate the work assigned to him.
• Recognition of potential hazards and how to prevent or correct them.
3.2 Notes on liability
The Eppendorf service organization entrusted with maintenance, servicing or testing is liable for ensuring
that all work is carried out in a professional manner.
 Repair, maintenance and testing may not change the existing construction of the device. The device
must always be as safe as it is in its original state.
 Only accessories and original spare parts recommended by Eppendorf, and measuring and test
equipment recommended by Eppendorf may be used for any maintenance, servicing or testing work.
Safety
English (EN)
3.3 Maintenance and repair hazards
DANGER! Electric shock.
 Switch off the device.

 Unplug the mains/power plug.
 Then begin repairing, servicing or cleaning the device.
DANGER! Risk of explosion.
 Do not operate the device in areas where work is completed with explosive substances.
 Do not use this device to process any explosive or highly reactive substances.
 Do not use this device to process any substances which could create an explosive
atmosphere.
WARNING! Infection by contaminated material.

There may be contaminated material on the device and accessories. Risk of infection with
contaminated material.
 Find out more about contamination risks before beginning work.

 Check the device decontamination certificate.
 Work may only be completed on a decontaminated device.
 Wear personal protective equipment (protective gloves, protective goggles).
WARNING! Burns from hot surfaces.

The metal surfaces of the thermoblocks and the hot plate reach temperatures in excess of
100°C.
 Do not touch any hot surfaces.

 Wait until the Eppendorf ThermoMixer or Eppendorf ThermoStat have cooled to ambient
temperature.
 Then start your test, maintenance or repair work.
CAUTION! Injury from sharp-edged components.

The opened device contains sharp-edged components. Risk of injury from sharp-edged
components.
 Wear protective gloves.

 Work with extreme care.
Operation
English (EN)
4 Operation
Operation
English (EN)
Troubleshooting
English (EN)
5 Troubleshooting
5.1 Error messages
The error messages will be displayed in the XX.YYY format:
 For the error analysis you need the digits YYY. The digits represent the error numbers
listed below.
All control commands, sensor signals and error signals are processed in the PCB Control.
Therefore the PCB Control and its supply lines such as cables and plug connections can
generally by the cause of every error.
 Check all cables and plug connections before exchanging assemblies.

 Use the test options in the service functions to determine the cause more accurately.
 Replace PCB Control only if all other possible causes have been excluded.
The PCB Control is only listed as a cause in the error list if there is no other hardware cause.
Problem Cause Solution

000 General error  Perform an initialization (“Factory
001 • General error Reset”).
002  Perform a software update.
003
(Will not be saved)
004 Communication with EEPROM  Perform an initialization (“Factory
005 • Communication with EEPROM Reset”).
006 interrupted.  Perform a software update.
(Will not be saved)
007 Initialization  Perform an initialization (“Factory
008 • EEPROM and/or device is not Reset”).
(Will not be saved) initialized properly.  Perform a software update.
009 Device type detection  Perform an initialization (“Factory
(Will not be saved) • The saved device settings do not Reset”).
match the device type detection of the  Replace keypad.
keypad.
(PCB is initialized on a different
device version.)
• Keypad not connected correctly.
• Keypad defective.
010 Keypad  Perform an initialization (“Factory
(Will not be saved) • No valid keypad detected. Reset”).
• Keypad not connected correctly.  Replace keypad.
• Keypad defective.
011 Communication with PCB Motor control  Replace PCB Motor control.
(Will not be saved) failed
• PCB Motor control not connected
correctly.
• PCB Motor control defective.
Troubleshooting
English (EN)

012 General error in the fan control  Check fan in service function.
• Fan not correctly connected.  Remove blockage.
• Fan stiff/blocked.  Replace defective fan.
• Fan defective.
013 Fan for switched-mode power supply  Check fan in service function.
• Fan not correctly connected.  Remove blockage.
• Fan stiff/blocked.  Replace fan for switched-mode power
• Fan defective. supply.
014 Fan for cooling  Check fan in service function.
015 • Fan not correctly connected.  Remove blockage.
• Fan stiff/blocked.  Replace fan for the cooling system.
• Fan defective.
016 SmartBlock/Thermoblock  Check block detection and
017 • No block attached. temperature sensors in the service
018 • Block contact insufficient. function.
019 • One or more temperature sensor(s)  SmartBlock: Clean the IR-interface on
defective. the SmartBlock and on the heating/
• Temperature difference in the block cooling plate and reattach
too high. SmartBlock.
• Setting temperature limit (dynamic  Thermoblock: Check plug connection.
limiting value) failed.  Replace SmartBlock.
• IR-interface faulty or contaminated.  Replace the thermoblock.
 Replace heating/cooling plate.
020 ThermoTop  Check ThermoTop detection and
021 • No ThermoTop attached. temperature sensors in the service
022 • Contact to the ThermoTop is function.
insufficient.  Clean contacts and reattach the
• One or more temperature sensor(s) ThermoTop.
defective.  Replace ThermoTop.
• Temperature difference within the  Clean IR interface.
ThermoTop is too great.
• IR-interface faulty or contaminated.
023 Mains/power supply  Perform a software update.
• PCB Motor control defective.  Replace PCB Motor control.
• Software crash.  Replace switched-mode power
• Switched-mode power supply supply.
defective.
024 Excess temperature  Check temperature sensors in the
• Temperature limit (dynamic limiting service function.
value) has been exceeded.  Replace SmartBlock.
• Temperature sensors in the  Replace the thermoblock.
SmartBlock/Thermoblock measure  Clean IR interface.
incorrectly.  Replace heating/cooling plate.
• IR-interface faulty or contaminated.
Troubleshooting
English (EN)

025 Excessive current to the motor  Reduce load.
• Forbidden load.  Remove blockage.
• Sluggish or blocked drive mechanism.  Perform a software update.
• PCB Motor control defective.  Replace PCB Motor control.
• Motor defective.  Replace motor.
• Stabilizer links defective.  Replace stabilizer links.
026 Simultaneous occurrence of several  See errors 24 and 25.
errors
• Errors 24 and 25 occurred at the
same time.
027 Overcurrent to the heating/cooling plate /  Replace heating/cooling plate.
Thermoblock  Replace the thermoblock.
• Heating/cooling plate/Thermoblock
defective.
errors
same time.
errors
same time.
030 Simultaneous occurrence of several  See errors 24, 25 and 27.
errors
• Errors 24, 25 and 27 occurred at the
same time.
031 Voltage supply  Check the voltage supply and connect
• Voltage supply too low. the device to another circuit if
• Switched-mode power supply required.
defective.  Replace switched-mode power
supply.
errors
same time.
errors
same time.
errors
same time.
Troubleshooting
English (EN)

errors
same time.
errors
same time.
errors
same time.
038 Simultaneous occurrence of several  See errors 24, 25, 27 and 31.
errors
• Errors 24, 25, 27 and 31 occurred at
the same time.
039 Current/power control  Perform an initialization (“Factory
• General error in the current/power Reset”).
control.  Perform a software update.
040 Cooling  Clean air duct and air intake/air
• Peltier element overheated. outlet.
• Air duct or air intake/air outlet  Clean heat sink.
blocked/contaminated.  Clean contact surfaces of Peltier
• Heat sink contaminated. element and heat sink.
• Insufficient contact between Peltier  Replace heating/cooling plate.
element and heat sink.
041 Temperature control  Replace heating/cooling plate.
• No current to the Peltier element.
042 Temperature control  Replace heating/cooling plate.
• No current to the heating foil.  Replace the thermoblock.
043 Temperature control of the ThermoTop  Repair contact between centering pin
• No current to the heating foil of the and ThermoTop.
ThermoTop.  Replace ThermoTop.
044 Watchdog  Perform an initialization (“Factory
• Internal time limit exceeded. Reset”).
 Perform a software update.
045 Fan control  Perform an initialization (“Factory
• The keep-alive signal in the fan Reset”).
control was not transmitted early  Perform a software update.
enough.  Replace PCB Motor control.
 Replace PCB Temperature control.
Troubleshooting
English (EN)

046 Motor control  Perform an initialization (“Factory
• The keep-alive signal in the motor Reset”).
enough.  Replace PCB Motor control.
047 Current/power control  Perform an initialization (“Factory
• The keep-alive signal of the current/ Reset”).
power control was not transmitted  Perform a software update.
early enough.  Replace switched-mode power
supply.
048 Temperature control  Perform an initialization (“Factory
• The keep-alive signal of the Reset”).
temperature control was not  Perform a software update.
transmitted early enough.
049 System control  Perform an initialization (“Factory
• The keep-alive signal of the system Reset”).
enough.
050 Heating  Replace heating/cooling plate.
• Initialization of thermal module failed.  Replace the thermoblock.
051 Heating  Check temperature sensors in the
• Query of heating foil temperature service function.
failed.  Replace heating/cooling plate.
 Replace the thermoblock.
052 Heating  Check temperature sensors in the
• Temperature difference between the service function.
two temperature sensors in the  Replace heating/cooling plate.
heating foil is too large.  Replace the thermoblock.
053 Drive  Remove blockage.
• Sluggish or blocked drive mechanism  Replace PCB Motor control.
(motor, stabilizer link, ...).  Replace motor.
• PCB Motor control defective.  Replace stabilizer links.
• Motor defective.
• Stabilizer links defective.
SmartBlock is not • IR-interface contaminated.  Clean IR interface.
detected. • SmartBlock defective.  Replace SmartBlock.
• Cable between the heating/cooling  Perform an initialization (“Factory
plate and the PCB Control is defective Reset”).
or not inserted correctly.  Perform a software update.
• Software version does not match the  Replace heating/cooling plate.
SmartBlock.
Troubleshooting
English (EN)
5.2 Service functions

5.2.1 Overview of service functions
Program number Program function

SE 01 error memory
SE 02 operating times/runs
SE 03 sensors
SE 04 key test
SE 05 motor
SE 06 fan
SE 07 memory reset
5.2.2 Activating the service functions
1. Switch off the device.

2. Press the menu/enter key and switch on the device. Press and hold the menu/enter until the device
name appears on the display.
3. Release the key and wait until the list of service functions appears on the display.
The service function is now activated.
Abb. 5-1: List of service functions
Fig. 5-1: List of service functions
The device must be switched off to exit the service functions.
5.2.3 Operating the service functions
• The operation of the service functions is the same as the menu operation in the normal operating mode.
• The service functions can be selected using the up/down arrow keys.
• Operate the menu/enter key to activate a service function or subfunction.
• To exit the service function or a subfunction, select the back menu item and operate the menu/enter
key.
Alternatively, for the Eppendorf ThermoMixer C and Eppendorf ThermoStat C, the left arrow
key can be used to exit the service function or subfunction, regardless of the menu item
selected.
Troubleshooting
English (EN)
5.2.4 SE 01 (error memory)
The last error message of the assembly/functional

unit is displayed.
 Select the history menu item and press the

menu/enter key to switch to the chronological
display of errors.
history subfunction:
The last 20 errors will be displayed in chronological
order.
The order is consecutively numbered: 1 = oldest
entry.
5.2.5 SE 02 (operating times/runs)
• Power on time: Sum of times during which the

device was switched on.
• Runtime: Sum of drive run times.
• Motorcycles: Number of completed motor
revolutions.
5.2.6 SE 03 (sensors)
• Temperature sensors in the SmartBlock/

SE 03 <sensors>
Block sensor 1 43.39 °C
Thermoblock (= Block), ThermoTop (= Lid) and
Block sensor 2 43.29 °C in the heating foil.
Lid sensor 1 n.a.
Lid sensor 2 n.a. • Height sensor of the plate block.
Heatfoil sensor 1 43.50 °C • Status messages on temperature, motor and
power supply.
5.2.7 SE 04 (key test)
 Press all keys one after the other. The

corresponding function will be shown as plain
text.
 Press the menu/enter key to exit the service
function.
5.2.8 SE 05 (motor)
Drive test
Display of the set speed and real speed.
Key functions:
• speed up/down: setting the speed.
• start/stop key: starting the drive.
Troubleshooting
English (EN)
5.2.9 SE 06 (fan)
Fan test
Fan:
• Power supply fan: max. 3 100 rpm (all devices).
• Primary heat sink fan: max. 5 600 rpm
(Eppendorf ThermoMixer C and Eppendorf
ThermoStat C only).
• Secondary heat sink fan: max. 5 600 rpm
(Eppendorf ThermoStat C only).
Key functions:
• up/down menu arrow keys: selecting the fan.
• speed up/down: setting the speed.
• start/stop key: starting the fan.
5.2.10 SE 07 (memory reset)
Resetting the memory
• Service: Reset the service memory (error list

and run data)
• Customer: Reset the customer settings and
programs.
• Factory Reset:
– Set the device version after replacing the
PCB Control.
– Reset all memories and settings to the factory
settings.
– Enter the serial number of the device.
– Set the display contrast.
Procedure:
1. Select the desired function.
2. Press the menu/enter key.
3. Confirm the confirmation request using the
down arrow key ("Yes" or "No").
4. Press the menu/enter key.
5. For Factory Reset only: Set the display contrast
with the temp up/down keys and save with
menu/enter.
6. For Factory Reset only: Enter the 12-digit device
serial number (see name plate) using the arrow
keys and save with menu/enter.
Disassembly/assembly
English (EN)
6 Disassembly/assembly
6.1 Tools
• Allen screwdriver: 2 mm/2.5 mm; length ≥100 mm

• Torx screwdriver: T10/T20
• Phillips screwdriver: size 1
6.2 Separating the upper part of housing and the chassis (disassembling
heating/cooling plate and thermoblock)
6.2.1 Eppendorf ThermoMixer C and Eppendorf ThermoStat C
Prerequisites
The SmartBlock has been removed.
Abb. 6-1: Heating/cooling plate with screws/housing screws Bottom of the device
3 3
Fig. 6-1: Heating/cooling plate with screws/housing screws Bottom of the device
1 Heating/cooling plate 3 Housing screws (old: 4 x 35 / new: 4 x 50/T20)

2 Screws for heating/cooling plate (M3 x 25/T10) 4 Screws for heat sink (M3 x 30/Allen key 2.5)
(Eppendorf ThermoStat C only)
English (EN)
1. Turn the device over.

2. Undo the housing screws from the bottom.
3. Only Eppendorf ThermoStat C: Undo the two heat sink screws on the bottom.
4. Place the device back on the feet.
5. Only Eppendorf ThermoMixer C: Remove the four rubber stoppers in the corners of the heating/cooling
plate.
6. Only Eppendorf ThermoMixer C: Undo the four screws in the corners of the heating/cooling plate.
7. Lift the upper part of housing together with the heating/cooling plate and disconnect the plug
connections of the cables at the same time.
8. Undo the ribbon cable of the heating/cooling plate.
9. Pull the strain relief (Fig. 6-2 on p. 27) out of the upper part of housing (it must be pushed open slightly
to do this).
10. Remove the heating/cooling plate.
Assembly notes:
 The strain relief consists of two parts. When fitting a new heating/cooling plate, the cable
conduit must be broken off at the predetermined breaking point before assembly. When
the strain relief has been positioned and the ribbon cable has been connected, the cable
conduit must be placed on the strain relief pin and engaged (see figures below).
 Push the strain relief fully back into the housing gap. It must fully rest on the front stop
(see figure below).
 Make sure that the cables are positioned correctly, in particular, the ribbon cable to the
heating/cooling plate. They may not be jammed or damaged.
 Pay attention to the ground contact at the front of the chassis. It must be pushed onto the
inside of the device housing (see figure below).
English (EN)
Abb. 6-2: Strain relief with predetermined breaking point/positioning of the cable conduit
2 2 3
Fig. 6-2: Strain relief with predetermined breaking point/positioning of the cable conduit
1 Cable conduit 3 Pin

2 Predetermined breaking points
Abb. 6-3: Fitting the strain relief/positioning the cable conduit
Fig. 6-3: Fitting the strain relief/positioning the cable conduit
Abb. 6-4: Ground contact (copper spring metal sheet)
Fig. 6-4: Ground contact (copper spring metal sheet)

English (EN)
6.2.2 Eppendorf ThermoMixer F0.5/F1.5/F2.0/FP

Abb. 6-5: Thermoblock with screws/housing screws Bottom of the device
3 3
37 °C 42 °C 56 °C 95 °C temp off
4
Fig. 6-5: Thermoblock with screws/housing screws Bottom of the device
1 Thermoblock 3 Housing screws (old: 4 x 35 / new: 4 x 50/T20)

2 Eppendorf ThermoMixer Fxx: screws for 4 Screws for heat sink (M3 x 30/Allen key 2.5)
thermoblock (M4 x 14/T20) (Eppendorf ThermoStat C only)
1. Turn the device over.

2. Remove the housing screws from the bottom.
3. Place the device back on the feet.
4. Remove the two screws from the thermoblock.
5. Lift the upper part of housing together with the thermoblock and disconnect the plug connections of the
cables at the same time.
6. Remove the ribbon cable from the thermoblock.
7. Pull the strain relief (Fig. 6-2 on p. 27) out of the upper part of housing.
8. Remove the thermoblock.
English (EN)
Assembly notes:
 The strain relief consists of two parts. When fitting a new thermoblock, the cable conduit
must be broken off at the predetermined breaking points before installation. When the
strain relief has been positioned and the ribbon cable has been connected, the cable
conduit must be placed on the strain relief pin and engaged (Fig. 6-3 on p. 27).
 Push the strain relief fully back into the housing gap. It must rest on the front stop.
 Make sure that the cables are positioned correctly, particularly the ribbon cable to the
thermoblock. They may not be jammed or damaged.
 Pay attention to the ground contact at the front of the chassis. It must be pushed onto the
inside of the upper part of housing (Fig. 6-4 on p. 27).
 The plastic plate on the ribbon cable from the thermoblock must be positioned in the
thermoblock adapter guide (see figure below).
Abb. 6-6: Guide for ribbon cable
5 °C
temp
off
Fig. 6-6: Guide for ribbon cable

English (EN)
6.3 Disassembly of upper part of housing

6.3.1 PCB control (incl. display)
Prerequisites
The upper part of housing has been separated from the chassis.
Abb. 6-7: PCB control, rear/housing insert for the IR-interface
5382 100.
28
PC/ABS
2 4
Fig. 6-7: PCB control, rear/housing insert for the IR-interface
1 PCB control with display 3 Housing insert for IR interface with mounting
screws (2 x Phillips EJ 2.5 x 8)
2 Mounting screws (EJ 3 x 8/T10)
4 O-ring
1. Disconnect the plug connections of the cables (excluding the ribbon cable to the display).
2. Unscrew the mounting screws.
3. Remove the PCB control from the upper part of housing.
Note the IR-interface. It is firmly inserted in the upper part of housing.
The ribbon cable to the IR interface may tear if you pull too hard!
 Carefully pull out the IR-interface together with the housing insert.
Assembly note:
 Make sure that the IR-interface and the sealing ring are positioned correctly.
An initialization ("Factory Reset") must be performed after the PCB control has been replaced!
English (EN)
6.3.2 Switched-mode power supply, USB interface and fan for switched-mode power
supply
Prerequisites
Abb. 6-8: Switched-mode power supply, USB interface and fan for switched-mode power supply
3
6
4 4
5
1 2
Fig. 6-8: Switched-mode power supply, USB interface and fan for switched-mode power supply
1 Switched-mode power supply 4 Screws for switched-mode power supply (EJ

3 x 8/T10)
2 USB interface
5 Screw für USB interface (M3 x 4/T10)
3 Fan for switched-mode power supply
6 Rubber straps for fan for switched-mode power
supply
1. Disconnect the plug connections of the cables.

2. Unscrew the screws of the switched-mode power supply.
3. Remove the complete assembly from the upper part of housing.
4. Undo the screw of the USB interface and remove the USB interface.
5. Pull the rubber straps of the fan for the switched-mode power supply and remove the fan.
6.3.3 Keypad and front clip
Prerequisites
1. Pull the keypad from the upper part of housing.

2. Remove the front clip from the upper part of housing.
Assembly note:
 Clean the bonding surface thoroughly before mounting the new keypad.
English (EN)
6.3.4 Centering pins (including PCB TT power)
Prerequisites
Abb. 6-9: Centering pins and PCB TT power in the upper part of housing
1 2
Fig. 6-9: Centering pins and PCB TT power in the upper part of housing
1 Centering pins 2 PCB TT power
1. Unscrew the centering pins from the upper part of housing.

2. Remove the connecting cable on the PCB control.
3. Remove the PCB TT power from the upper part of housing.
English (EN)
6.4 Disassembly from the chassis Eppendorf ThermoMixer C and Eppendorf

ThermoMixer Fxx
6.4.1 Orbital plate
Prerequisites
The upper part of housing has been removed.
Abb. 6-10: Thermoblock adapter
2
1
Fig. 6-10: Thermoblock adapter
1 Thermoblock adapter 2 Screws for thermoblock adapter (M3 x 25/T10)

Abb. 6-11: Orbital plate with screws
3 4
5
5
Fig. 6-11: Orbital plate with screws
3 Screws for upper locking ring (M4 x 10/T20) 5 Screws for orbital plate (M4 x 12/T20)
4 Orbital plate
English (EN)
1. Only Eppendorf ThermoMixer Fxx: Undo the thermoblock adapter screws and remove the thermoblock
adapter.
2. Loosen the screws on the upper locking ring (only loosen, do not remove!).
3. Remove the screws from the ground cable and the orbital plate and lift off the orbital plate.
Assembly notes:
 During assembly, tighten the locking ring screws last and evenly (in sequence). The
locking ring must not tilt.
 Do not overtighten the screws for the locking ring and the orbital plate, as this could
damage the threads in the locking ring or in the plastic of the stabilizer links.
6.4.2 Imbalance eccentric
Prerequisites
The upper part of housing and the orbital plate have been removed.
Abb. 6-12: Imbalance eccentric
Fig. 6-12: Imbalance eccentric
1 Imbalance eccentric 3 Screws for lower locking ring (M4 x 6/T20)

2 Clamping screw of the imbalance eccentric
(M4 x 6/Allen key 2 mm)
1. Loosen the screws on the lower locking ring (only loosen, do not remove!).
2. Loosen the clamping screw of the imbalance eccentric slightly (1 turn max.).
3. Lift off the imbalance eccentric. Note: The bottom ball bearing of the imbalance eccentric is glued to the
motor casing (Fig. 6-13 on p. 36). If the imbalance eccentric is seated too firmly, it can be levered up
carefully and smoothly with two screwdrivers that are applied opposite each other.
English (EN)
Assembly notes:
 Apply a small amount of Loctite® 603™ around the bottom ball bearing of the imbalance
eccentric. Remove any glue residue first.
 During assembly, tighten the locking ring screws evenly (in sequence). The locking ring
must not tilt.
 Do not overtighten the locking ring screws. This could damage the thread in the locking
ring.
 Tighten the clamping screw of the imbalance eccentric last.
English (EN)
6.4.3 Motor
Prerequisites
The upper part of housing, the orbital plate and the imbalance eccentric have been removed.
Abb. 6-13: Motor casing
2
2
Fig. 6-13: Motor casing
1 Motor casing 2 Screws for motor casing (M4 x 20/T20)

Abb. 6-14: Motor
6 6
Fig. 6-14: Motor
3 Motor 5 Air duct

4 PCB motor control 6 Circlips on the PCB motor control
English (EN)
1. Undo the screws on the motor casing.

2. Remove the two circlips on the PCB motor control.
3. Lift off the motor casing.
4. Remove the motor and undo the contact to the PCB motor control at the same time.
Assembly note:
 Insert the imbalance eccentric before tightening the screws.
 Then tighten the screws on the motor casing and on the locking ring (refer to the assembly
notes for the imbalance eccentric).
 Tighten the clamping screw of the imbalance eccentric last.
6.4.4 PCB motor control
Prerequisites
The upper part of housing, the orbital plate, the imbalance eccentric and the motor have been removed.
Abb. 6-15: PCB motor control in the Eppendorf ThermoMixer C
Fig. 6-15: PCB motor control in the Eppendorf ThermoMixer C
1 PCB motor control 3 Air duct

2 Ribbon cable
Pay attention to the ribbon cable and how it is laid! During assembly, it must be laid in the
same position again.
1. Eppendorf ThermoMixer C: Pull the PCB motor control out of the air duct (clamped).
2. Eppendorf ThermoMixer Fxx: Remove the retaining plate from the ribbon cable (Fig. 6-17 on p. 39) and
remove the PCB motor control.
On the Eppendorf ThermoMixer Fxx, the PCB motor control can also be removed without
disassembling the orbital plate, the imbalance eccentric and the motor (see Fig. 6-17 on
p. 39).
 Pull off the circlips and remove the PCB motor control together with the cover.
English (EN)
6.4.5 Stabilizer links
Prerequisites
The upper part of housing and the orbital plate have been removed.
Abb. 6-16: Stabilizer links
3 2 1 3
3 1 2 3
Fig. 6-16: Stabilizer links
1 Stabilizer links 3 Screws for stabilizer links (M4 x 16/T20)

2 Screws for stabilizer links (M4 x 25/T20)
 Undo the screws and remove the stabilizer links.
6.4.6 Fan for cooling (Eppendorf ThermoMixer C only)
Prerequisites
The upper part of housing, the orbital plate, the imbalance eccentric, the motor and the PCB motor control
have been removed.
(see Fig. 6-15 on p. 37)
 Push the air duct and the fan downward out of the base plate.
English (EN)
6.4.7 Chassis closing (Eppendorf ThermoMixer Fxx only)
Prerequisites
The upper part of housing has been removed.
Abb. 6-17: Chassis closing
1 3 2 5
Fig. 6-17: Chassis closing
1 Chassis closing 4 Circlips

2 Ribbon cable retaining plate 5 PCB motor control cover
3 Retaining plate screws (M4 x 8/T20)
1. Undo the retaining plate screws (from the base, below the device feet).
2. Remove the retaining plate.
3. Remove the two circlips on the PCB motor control.
4. Pull the PCB motor control off with the cover.
5. Press the chassis closing downwards.
English (EN)
6.5 Dismantling the Eppendorf ThermoStat C chassis

6.5.1 PCB temperature control
Prerequisites
• The upper part of housing has been removed.
Abb. 6-18: PCB temperature control
1 2 3
Fig. 6-18: PCB temperature control
1 PCB temperature control 3 Ribbon cable

2 Bracket
1. Push the bracket slightly up.

2. Remove the PCB temperature control.
English (EN)
6.5.2 Fan for cooling
Prerequisites
• The upper part of housing has been removed.
• The PCB temperature control has been removed.
Abb. 6-19: Air duct
1 2
Fig. 6-19: Air duct
1 Air duct 3 Screws for heat sink (M4x10/T20)

2 Heat sink
1. Unscrew the screws from the heat sink.

2. Pull the heat sink out to the rear right.
3. Push the air duct with the fans up and out.
6.6 Device assembly
With all assembly steps, install in reverse order. Also observe chapter 7 "Alignment/adjustment" and the
notes in the disassembly instructions during assembly.
English (EN)
Alignment/adjustment
English (EN)
7 Alignment/adjustment
7.1 Setting and adjusting
7.1.1 Setting the electronics
After replacing the PCB control you have to perform an initialization (factory reset) (see
p. 24).
7.1.2 Temperature adjustment
The temperature does not need to be adjusted.
The SmartBlocks and thermoblocks are equipped with correction data during production. The correction
data cannot be changed later.
This also applies for spare parts. The temperature cannot and does not need to be adjusted after replacing
SmartBlocks and thermoblocks.
7.1.3 Mechanical adjustment
During assembly, make sure that the cables are positioned correctly, that the movable parts and assemblies
can move freely and, generally, that the individual parts and assemblies fit together.
Observe the notes in the disassembly/assembly instructions.

Alignment/adjustment
English (EN)
Software
English (EN)
8 Software
8.1 Software update
Printed circuit boards do not always have the latest software or firmware versions installed.
 Check the software and firmware versions after replacing the PCBs.
 Update the software and firmware if necessary.
You can update the device software with a computer via the USB interface of the device.
The USB interface is located on the rear of the device.
To enable communication between the devices and the computer you need to install the "Universal Device
Firmware Upgrade (UDFU)" software (version 1.1.7.0 or higher), the required drivers and Microsoft.NET
Framework on your computer.
The UDFU software with drivers and operating manual is available for download on
www.eppendorf-support.com (password required).
The latest firmware version can also be downloaded from www.eppendorf-support.com.
Read the UDFU software operating manual and the firmware installation instructions before
starting to download, install or update the software or firmware.
8.2 Bootloader
A faulty update or an interruption during the update can damage the firmware. It is possible that the device
can then no longer be operated and the display may be blank. In this case, the device can be switched to
bootloader mode and the firmware can be installed again.
1. Switch off the device.

2. Hold the start/stop + menu/enter keys. Simultaneously switch on the device.
The device is in bootloader mode. The display remains dark.
3. Start the firmware update again.
Software
English (EN)
Diagrams
English (EN)
9 Diagrams
9.1 Eppendorf ThermoMixer C
Diagrams
English (EN)
9.2 Eppendorf ThermoStat C
≤
Diagrams
English (EN)
9.3 Eppendorf ThermoMixer F0.5/F1.5/F2.0

Diagrams
English (EN)
9.4 Eppendorf ThermoMixer FP

Maintenance
English (EN)
10 Maintenance
10.1 Cleaning, disinfection, decontamination
DANGER! Electric shock as a result of penetration of liquid.
 Switch off the device and disconnect the mains/power plug before starting cleaning or
disinfection work.
 Do not allow any liquids to penetrate the inside of the housing.
 Use closed tubes and closed plates.
 Do not spray clean/spray disinfect the housing.
 Only plug the device back in if it is completely dry, both inside and outside.
WARNING! Infection by contaminated material.

There may be contaminated material on the device and accessories. Risk of infection with
contaminated material.
 Find out more about contamination risks before beginning work.

 Check the device decontamination certificate.
 Work may only be completed on a decontaminated device.
 Wear personal protective equipment (protective gloves, protective goggles).
NOTICE! Damage from the use of aggressive chemicals.
 Do not use any aggressive chemicals on the device or its accessories, such as strong and
weak bases, strong acids, acetone, formaldehyde, halogenated hydrocarbons or phenol.
 If the device becomes contaminated with aggressive chemicals, clean it immediately using
a mild cleaning agent.
NOTICE! Corrosion due to aggressive cleaning agents and disinfectants.
 Do not use corrosive cleaning agents, aggressive solvents or abrasive polishes.

 Do not incubate the accessories in aggressive cleaning agents or disinfectants for a longer
period of time.
For further information as well as a detailed description on how to perform cleaning,

disinfection and decontamination, please refer to the operating manual of the device.
Carefully read the respective sections of the operating manual before you start cleaning,
disinfection or decontamination.
Maintenance
English (EN)
10.2 Shipping the device
WARNING! Risk to health from contaminated device

1. Follow the instructions in the decontamination certificate. You can find it as a PDF file on
our website (www.eppendorf.com/decontamination).
2. Decontaminate all the parts you would like to dispatch.
3. Include the fully completed decontamination certificate in the packing.
NOTICE! Damage as a result of incorrect packing.

Eppendorf AG is not liable for damage caused by incorrect packing.
 The device may only be stored and transported in its original packing.
Transport packing can be ordered via your Eppendorf service organization. The order number
can be found in the chapter Ordering information.
10.3 Service and inspection

10.3.1 Essential check
Check duration: approx. 15 minutes per device.
Visual check of exterior.  Check all external parts for visible damages, e.g.
housing, chassis, device feet.
Visual check of accessories (if available).  Check the exterior of the accessories for visible
• SmartBlocks damages.
• ThermoTop
• Lid
Check of SmartBlock detection (TMC and TSC).  Attach each available SmartBlock one after the
other. Check whether all SmartBlocks are
correctly detected and indicated on the display.
Functional check (without measurement)  Mixing: Set various arbitrary speeds and start
• Mixing (TMC and TMFxx) the drive. Check whether the device runs
• Heating (TMC, TMFxx and TSC) correctly and without unusual noises.
• Cooling (TMC and TSC).  Heating: Set an arbitrary temperature higher
than the ambient temperature. Check whether
the temperature of the SmartBlock or the
Thermoblock is rising. Risk of burns: Do not set
the temperature too high!
 Cooling: Set an arbitrary temperature lower than
the ambient temperature. Check whether the
temperature of the SmartBlock is reducing.
Maintenance
English (EN)
10.3.2 Advanced maintenance
Check duration: approx. 45 minutes per device.
Cleaning of exterior.  Clean the device according to the description in

the operating manual and the hints in the service
manual.
Visual check of exterior.  Check all external parts for visible damages, e.g.
housing, chassis, device feet.
Cleaning of internal parts and assemblies.  Remove any dust and dirt from all internal parts
and assemblies.
Note: Avoid damage to the electronics from
moisture or electrostatic charge!
Visual check of internal parts and assemblies.  Check all internal parts for visible damages, e.g.
housing, drive, stabiliser links, cables.
 Check that all the connectors are securely fitted.
Visual check of electrical connection.  Check the power cord for visible damages.
 Check that the connectors are securely fitted in
the device and in the power outlet.
 Check that the mains input module inside the
device is securely fitted and undamaged.
Cleaning of accessories (if available).  Clean the accessories according to the
• SmartBlocks description in the operating manual and the
• ThermoTop hints in the service manual.
• Lid  Pay particular notice to the optical inductive
interface on the SmartBlock and on the
ThermoTop.
Visual check of accessories (if available).  Check the exterior of the accessories for visible
• SmartBlocks damages.
• ThermoTop
• Lid
LED and display check.  Switch on the device and observe whether the
text and the symbols are correctly displayed
during the following check stages.
 Check that the contrast settings ensure proper
readability.
 Actuate all program keys or temperature keys
one after the other. Check that the
corresponding LED is working
Reading-out and evaluating of stored data.  SE 01: read out and analyze the error list. Take
• SE 01 (error memory) further action if required.
• SE 02 (operating times/runs)  SE 02: read out and analyze the run times.
Maintenance
English (EN)
Functional check with service functions:  SE 03: Attach all available SmartBlocks. Check
• SE 03 (sensors) temperature sensors in all SmartBlocks and the
• SE 04 (key test) height sensor of the SmartBlock plates if
• SE 05 (motor) necessary.
• SE 06 (fan)  SE 03: Attach ThermoTop (if available). Check
the temperature sensors in the ThermoTop.
 SE 04: Actuate all buttons one after the other.
Check that all buttons are correctly displayed.
 SE 05: Start the motor at different speeds. Check
that all selected speeds are attained properly.
 SE 06: Start all fans at different speeds one after
the other. Check that all selected speeds are
attained properly.
Check of SmartBlock detection (TMC and TSC).  Attach each available SmartBlock one after the
other. Check whether all SmartBlocks are
correctly detected and indicated on the display.
Functional check (without measurement)  Mixing: Set various arbitrary speeds and start
• Mixing (TMC and TMFxx) the drive. Check whether the device runs
• Heating (TMC, TMFxx and TSC) correctly and without unusual noises.
• Cooling (TMC and TSC).  Heating: Set an arbitrary temperature higher
than the ambient temperature. Check whether
the temperature of the SmartBlock or the
Thermoblock is rising. Risk of burns: Do not set
 Cooling: Set an arbitrary temperature lower than
the ambient temperature. Check whether the
temperature of the SmartBlock is reducing.
Check of ThermoTop detection and function (only if  Attach the ThermoTop and set an arbitrary
the customer uses the ThermoTop). temperature higher than the ambient
temperature. Check whether the ThermoTop is
detected (symbol on the display and LED on the
ThermoTop) and if the temperature of the
ThermoTop increases. Risk of burns: Do not set
10.3.3 Qualification services - operational qualification (OQ)
Eppendorf recommends checking the essential technical data and functions of the devices at least once per
year in accordance with the OQ checklist.
The OQ checklist is available on the Internet at www.eppendorf-support.com (password required) or on

request.
Detailed descriptions of how to perform the individual measurements can be found in the "Device
inspection" chapter.
Check duration: approx. 45 - 60 minutes per device.

Maintenance
English (EN)
10.4 Device inspection
The applicable tolerances and limiting values can be found in the "Technical data" chapter.
Perform the device test at an ambient temperature of 22°C ± 2°C.
10.4.1 Temperature check

Abb. 10-1: Test bore for temperature measurement, example thermoblock 1.5 mL
1 2
A 3 4 5 6
B
Fig. 10-1: Test bore for temperature measurement, example thermoblock 1.5 mL
The temperature of the thermoblock is checked on all devices and SmartBlocks with the "Temperature
Verification System - single-channel" and the "Temperature sensor 384". All thermoblocks have a test bore
that matches the sensor.
Measuring device
• Temperature verification system - single-channel (0055 000.298 / 0056 000.003) with temperature
sensor 384 (5331 233.007 / 0056 002.006)
Measurement procedure:
1. Mount a SmartBlock (Eppendorf ThermoMixer C and Eppendorf ThermoStat C only).
2. Remove the stopper of the test bore.
3. Position the temperature sensor in the SmartBlock or thermoblock.
4. Equip SmartBlock or thermoblock with vessels.
5. Set the test temperature.
6. Wait until the test temperature has been reached and is stable.
7. Note the measuring result.
8. Repeat steps 4 to 6 for other temperatures.
Maintenance
English (EN)
10.4.2 Speed check
Measuring device
• Digital rotation meter, suitable for non-contact measurement.
• Measuring range: 1 to ≥ 9,999 rpm
• Accuracy: ≤ 0.1 %
1. Mount a SmartBlock (Eppendorf ThermoMixer C only).
2. Mark the SmartBlock or thermoblock using a reflector (accessory for the measuring device).
3. Start the Eppendorf ThermoMixer with the desired rotational speed. Let the Eppendorf ThermoMixer
run briefly until the speed has stabilized.
4. Measure the speed (as described in the operating manual of the measuring device).
5. Note the measuring result.
6. If required, repeat steps 3 to 5 for other rotational speeds.
10.4.3 Timer check
Measuring device
• Stopwatch
• Accuracy: ≤ 0.1 s
1. Set a run time of > 5 minutes.
2. Start the device and the stopwatch simultaneously.
3. Let the device run for 5 minutes.
4. Compare the time displayed on the device and the time measured with the stopwatch.
10.5 Electrical safety check
Effective standard
• Pre-IEC 62638 (international)
• VDE 701/702 (Germany)
• NFPA 99 (USA)
Notes concerning the measuring procedure:

• Testing electrical safety may only be carried out by a suitably trained electrician.
• Measurement is carried out on a grounded, metallic point on the lower part of the housing/chassis that
is not insulated and can be touched from the outside.
• Never use any interfaces that may be present for measuring. This could damage the electronic system of
the device.
• Never use the centering pins (Fig. 6-9 on p. 32) for measuring. This could damage the electronic system
of the device.
• Due to the internal electrical design the insulation resistance cannot be measured!
• Due to the internal electrical design the equivalent leakage current cannot be measured!
–> Always measure the real leakage current (direct measurement or differential current measurement).
Technical data
English (EN)
11 Technical data
11.1 Power supply
Power connection 100 V – 130 V ±10 %, 50 Hz – 60 Hz

220 V – 240 V ±10 %, 50 Hz – 60 Hz
Power consumption Maximum 200 W
Overvoltage category II
Degree of pollution 2
Protection class I
11.2 Weight/dimensions
Width 20.6 cm (8.1 in)

Depth 30.4 cm (12.0 in)
Height Eppendorf ThermoMixer C: 13.6 cm (5.4 in)
Eppendorf ThermoStat C: 13.6 cm (5.4 in)
Eppendorf ThermoMixer F0.5: 16.3 cm (6.4 in)
Eppendorf ThermoMixer FP: 16.4 cm (6.5 in)
Weight Eppendorf ThermoMixer C: 6.3 kg (13.9 lb)
Eppendorf ThermoStat C: 4.4 kg (9.7 lb)
Eppendorf ThermoMixer F0.5: 6.2 kg (13.7 lb)
Eppendorf ThermoMixer FP: 6.1 kg (13.4 lb)
11.3 Ambient conditions
Ambience Only for use indoors.

Ambient temperature 5 °C – 40 °C
Relative humidity 10 % – 90 %, non-condensing.
Atmospheric pressure 79.5 kPa – 106 kPa
Technical data
English (EN)
11.4 Tolerances
11.4.1 Temperature accuracy
The accuracy of the temperature verification system - single-channel with the temperature
sensor 384 (± 0,3 °C) has been taken into consideration in the tolerance data below. Therefore,
this data is different to the technical data in the operating manual.
 Please refer to the notes on temperature checks in chapter 10, “Maintenance".
Tab. 11-1: Eppendorf ThermoMixer C and Eppendorf ThermoStat C

SmartBlock Accuracy 20 - 45 °C Accuracy < 20 °C and > 45 °C
Eppendorf Eppendorf Eppendorf Eppendorf
ThermoMixer C ThermoStat C ThermoMixer C ThermoStat C
0.5 mL ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
1.5 mL ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
2.0 mL ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
PCR 96 ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
PCR 384 ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
cryo ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
12 mm ± 0.8 °C ± 0.8 °C ± 1.3 °C ± 1.3 °C
plates ± 1.3 °C ± 1.3 °C ± 4.3 °C ± 3.3 °C
5 mL ± 1.3 °C ± 1.3 °C ± 4.3 °C ± 2.3 °C
15 mL ± 1.3 °C ± 1.3 °C ± 4.3 °C ± 2.3 °C
50 mL ± 1.3 °C ± 1.3 °C ± 4.3 °C ± 2.3 °C
Tab. 11-2: Eppendorf ThermoMixer Fxx

Device Accuracy 20 - 45 °C Accuracy < 20 °C and > 45 °C
Eppendorf ThermoMixer F0.5 ± 0.8 °C ± 0.8 °C
Eppendorf ThermoMixer FP ± 1.3 °C ± 4.3 °C
Technical data
English (EN)
11.4.2 Temperature homogeneity
Tab. 11-3: Eppendorf ThermoMixer C and Eppendorf ThermoStat C

SmartBlock Homogeneity 20 - 45 °C Homogeneity < 20 °C and > 45 °C
Eppendorf Eppendorf Eppendorf Eppendorf
ThermoMixer C ThermoStat C ThermoMixer C ThermoStat C
0.5 mL ± 0.5°C ± 0.5°C ± 1°C ± 1°C
1.5 mL ± 0.5°C ± 0.5°C ± 1°C ± 1°C
2.0 mL ± 0.5°C ± 0.5°C ± 1°C ± 1°C
PCR 96 ± 0.5°C ± 0.5°C ± 1°C ± 1°C
PCR 384 ± 0.5°C ± 0.5°C ± 1°C ± 1°C
cryo ± 0.5°C ± 0.5°C ± 1°C ± 1°C
12 mm ± 0.5°C ± 0.5°C ± 1°C ± 1°C
plates ± 0.5°C ± 0.5°C ± 2 °C ± 2 °C
5 mL ± 0.5°C ± 0.5°C ± 2 °C ± 2 °C
15 mL ± 0.5°C ± 0.5°C ± 2 °C ± 2 °C
50 mL ± 0.5°C ± 0.5°C ± 2 °C ± 2 °C
Tab. 11-4: Eppendorf ThermoMixer Fxx

Device Homogeneity 20 - 45 °C Homogeneity < 20 °C and > 45 °C
Eppendorf ThermoMixer F0.5 ± 0.5°C ± 1.5°C
Eppendorf ThermoMixer FP ± 0.5°C ± 1.5°C
11.4.3 Speed
Parameters Accuracy
Speed ±3%
11.4.4 Time
Parameters Accuracy
Timer 5 min ± 2 s
Technical data
English (EN)
Ordering information
English (EN)
12 Ordering information
12.1 Figures
Abb. 12-1: Front view
1-5 3-6 1-1
prog 5
prog 4
prog 3
prog 2
prog 1
short
menu
enter speed
temp
time
start
stop
1-2
Fig. 12-1: Front view

English (EN)
Abb. 12-2: Drive mechanism and air duct
2-3
4-1 2-4 2-2
2-2 2-1
Fig. 12-2: Drive mechanism and air duct

English (EN)
Abb. 12-3: Upper part of housing with electronics
3-5 3-2
5-2
4-3
1-5
1-1
3-1
Fig. 12-3: Upper part of housing with electronics

English (EN)
Abb. 12-4: View from below
1-4
1-3
4-1
Fig. 12-4: View from below

English (EN)
Abb. 12-5: PCB motor control and fan for cooling (including air duct)
3-4 4-1
Fig. 12-5: PCB motor control and fan for cooling (including air duct)
English (EN)
Abb. 12-6: Eppendorf ThermoMixer Fxx, internal view
3-10
3-4
4-4
Fig. 12-6: Eppendorf ThermoMixer Fxx, internal view

English (EN)
Abb. 12-7: Eppendorf ThermoStat C, internal view
3-3 3-7 4-2
Fig. 12-7: Eppendorf ThermoStat C, internal view

English (EN)
Abb. 12-8: Thermoblock 1.5 mL
Fig. 12-8: Thermoblock 1.5 mL

English (EN)
Abb. 12-9: Thermoblock plates
Fig. 12-9: Thermoblock plates

English (EN)
Abb. 12-10: Locking ring
Fig. 12-10: Locking ring

English (EN)
12.2 Spare parts
Product numbers
• 5382: Eppendorf ThermoMixer C (TMC)
• 5383: Eppendorf ThermoStat C (TSC)
• 5385: Eppendorf ThermoMixer FP (TMFP)
12.2.1 Housing
Fig. Item Order no. Description
5382
5383
5384
5385
5386
5387
(International)
Upper part of housing
w/o keypad
12-1 / 12-3 1-1 5382 850.019 TMC/TSC/TMF X X X X X X
Keypad
incl. Frontclip
12-1 1-2 5382 850.060 TMC X
12-1 1-2 5383 850.063 TSC X
12-1 1-2 5384 850.067 TMF1.5 X
12-1 1-2 5385 850.060 TMFP X
12-1 1-2 5386 850.064 TMF0.5 X
12-1 1-2 5387 850.068 TMF2.0 X
Spherical foot
12-4 1-3 5355 863.001 4 pieces X X X X X X
Spherical support
12-4 1-4 5353 861.001 4 pieces X X X X X X
Centering pin
12-1 / 12-3 1-5 5382 850.035 2 pcs., incl. PCB TT-Power X X X X X X
12.2.2 Drive

5382
5383
5384
5385
5386
5387
(International)
Motor
12-2 2-1 5382 850.108 TMC/TMF X X X X X
Stabilizer link
set = 2 pieces
12-2 2-2 5382 850.205 TMC/TMF X X X X X
Imbalance eccentric
incl. ball bearing
12-2 2-3 5382 850.302 TMC X
12-2 2-4 5384 850.300 TMF X X X X
Locking ring 2 pcs
12-10 2-6 5382 850.400 TMC/TMF X X X X X
English (EN)
12.2.3 Electronics
In some cases, the software/firmware version of the PCB(s) does not match the current status.
 After replacing the printed circuit board(s) check the software version and update it, if
required.
5382
5383
5384
5385
5386
5387
(International)
PCB Control
with display
12-3 3-1 5382 850.507 TMC/TSC/TMF X X X X X X
Switched-mode power supply
12-3 3-2 5382 850.604 incl. mains input module X X X X X X
PCB temperature control
12-7 3-3 5383 850.705 TSC X
PCB motor control
12-5 / 12-6 3-4 5382 850.701 TMC X
12-5 / 12-6 3-4 5384 850.105 TMF X X X X
USB interface
Heating/cooling plate
12-1 3-6 5382 851.007 TMC X
12-7 3-7 5383 851.000 TSC X
Thermoblock
12-8 3-8 5384 851.004 TMF1.5 X
12-9 3-9 5385 851.008 TMFP X
(12-8) 3-11 5386 851.001 TMF0.5 X
(12-8) 3-12 5387 851.005 TMF2.0 X
Adapter for thermoblock
12-6 3-10 5384 851.209 TMF X X X X
12.2.4 Fan

5382
5383
5384
5385
5386
5387
(International)
Fan
incl. air duct
12-2 / 12-4 / 4-1 5382 851.104 TMC
12-5 X
12-7 4-2 5383 851.108 TSC X
Fan
for switched-mode power supply
Chassis closing
12-6 4-4 5384 851.101 TMF X X X X
English (EN)
12.2.5 Accessories/auxiliary aids
5382
5383
5384
5385
5386
5387
(International)
Packing
---- 5-1 5382 851.406 TMC/TSC/TMF X X X X X X
Mounting elements
incl. cable
(12-3) 5-2 5382 851.201 TMC/TSC/TMF X X X X X X
Temperature Verification System USB –
Single channel
---- 5-3 0056 000.003 For Mastercycler nexus, Mastercycler pro X X X X X X
und Mastercycler ep, Eppendorf
ThermoMixer, Eppendorf ThermoStat
Temperature sensor
for Temperature Verification System
USB – Single channel
---- 5-4 0056 002.006 384 Well X X X X X X
USB software cable
---- 5-5 5428 850.280 USB-A/USB-B X X X X X X
12.2.6 SmartBlocks

5382
5383
5384
5385
5386
5387
(International)
Eppendorf ThermoTop
---- 6-1 5308 000.003 with condens.protect technology X X X X X X
Lid
for Eppendorf ThermoMixer F0.5/F1.5/
F2.0/FP
---- 6-2 5363 000.233 for SmartBlocks 0.5 mL, 1.5 mL, 2.0 mL,
plates, PCR 96, PCR 384 X X X X X X
SmartBlock 0.5 mL
---- 6-3 5361 000.031 Thermoblock for 24 tubes 0.5 mL X X
SmartBlock 1.5 mL
SmartBlock 2.0 mL
SmartBlock 5.0 mL
SmartBlock 15 mL
---- 6-7 5366 000.021 Thermoblock for 8 conical tubes 15 mL X X
SmartBlock 50 mL
---- 6-8 5365 000.028 Thermoblock for 4 conical tubes 50 mL X X
SmartBlock 12 mm
Thermoblock for 24 tubes
---- 6-9 5364 000.024 diameter 11 mm – 11.9 mm, height
34 mm – 76 mm X X
English (EN)
5382
5383
5384
5385
5386
5387
(International)
SmartBlock cryo
Thermoblock for 24 Cryo tubes
---- 6-10 5367 000.025 1.5 mL – 2 mL, diameter max. 12,5 mm,
all base shapes X X
SmartBlock plates
Thermoblock for microplates and
deepwell plates
---- 6-11 5363 000.039 incl. Lid X X
SmartBlock PCR 96
Thermoblock for PCR plates 96
---- 6-12 5306 000.006 incl. Lid X X
SmartBlock PCR 384
Thermoblock for PCR plates 384
---- 6-13 5307 000.000 incl. Lid X X
Transfer Rack 1.5/2.0 mL
---- 6-14 3880 000.151 for 1.5/2.0 mL tubes X X X X
Transfer Rack 0.5 mL
---- 6-15 3880 000.305 for 0.5 mL tubes X X X
12.3 Spare parts proposals – initial equipment

5382
5383
5384
5385
5386
5387
(International)
Motor
12-2 2-1 5382 850.108 TMC/TMF X X X X X
PCB Control
with display
Heating/cooling plate
12-1 3-6 5382 851.007 TMC X
12-7 3-7 5383 851.000 TSC X
Thermoblock
12-8 3-8 5384 851.004 TMF1.5 X
12-9 3-9 5385 851.008 TMFP X
(12-8) 3-11 5386 851.001 TMF0.5 X
(12-8) 3-12 5387 851.005 TMF2.0 X
Mounting elements
incl. cable
(12-3) 5-2 5382 851.201 TMC/TSC/TMF X X X X X X
Technical information
English (EN)
13 Technical information
Technical information
English (EN)
Evaluate Your Manual
Give us your feedback.

www.eppendorf.com/manualfeedback
Your local distributor: www.eppendorf.com/contact

Eppendorf AG · 22331 Hamburg · Germany
eppendorf@eppendorf.com · www.eppendorf.com

Service-Manual ThermoMixer-C F0.5 F1.5 F2.0 FP ThermoStat-C Eng PDF

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1.2 Danger symbols and danger levels

1.2.1 Danger symbols

Biological hazard Explosive substances

Electric shock Hot surface

Cuts Hazard point

1.2.2 Danger levels

DANGER Will lead to severe injuries or death.

1.3 Symbols used

Product numbers, device names and abbreviations

All devices consist of the following assemblies:

2.2.2 Upper part of housing

2.2.4 PCB control

2.2.5 PCB motor control

2.2.6 PCB temperature control

2.2.7 Heating/cooling plate

2.2.10 Fan for cooling and for the electronic system

Depending on the device model, up to three fans are used:

• Eppendorf ThermoMixer Fxx: A fan for the switched-mode power supply.

2.2.11 Switched-mode power supply

2.2.12 USB interface

3.2 Notes on liability

3.3 Maintenance and repair hazards

DANGER! Electric shock.

 Switch off the device.

DANGER! Risk of explosion.

WARNING! Infection by contaminated material.

 Find out more about contamination risks before beginning work.

WARNING! Burns from hot surfaces.

 Do not touch any hot surfaces.

CAUTION! Injury from sharp-edged components.

 Wear protective gloves.

 Check all cables and plug connections before exchanging assemblies.

Problem Cause Solution

Problem Cause Solution

Problem Cause Solution

Problem Cause Solution

Problem Cause Solution

5.2 Service functions

Program number Program function

5.2.2 Activating the service functions

1. Switch off the device.

Fig. 5-1: List of service functions

The device must be switched off to exit the service functions.

5.2.3 Operating the service functions

5.2.4 SE 01 (error memory)

The last error message of the assembly/functional

 Select the history menu item and press the

5.2.5 SE 02 (operating times/runs)

• Power on time: Sum of times during which the

• Temperature sensors in the SmartBlock/

5.2.7 SE 04 (key test)

 Press all keys one after the other. The

5.2.10 SE 07 (memory reset)

Resetting the memory

• Service: Reset the service memory (error list

• Allen screwdriver: 2 mm/2.5 mm; length ≥100 mm

1 Heating/cooling plate 3 Housing screws (old: 4 x 35 / new: 4 x 50/T20)

1. Turn the device over.

1 Cable conduit 3 Pin

Abb. 6-3: Fitting the strain relief/positioning the cable conduit