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Author/s:: Schmid Daniel, Schürch Cornelia and Zülli Fred, Mibelle AG Biochemistry
Abstract:
In summer time at the beach, people know that they have to protect
themselves with sun creams against sunburn. But sunlight affects our skin every day of
the year, which finally leads to premature skin aging, also called photo- aging. This is
shown by the fact that permanent exposed skin sites, such as the face and hands show
in general more aging signs than covered skin. The principal etiologic factor of
premature skin aging is UV-A. Unlike UV-B, UV-A is not dependent on time of day or
season, and it penetrates rather well through clouds and window glass. Skin therefore
need protection against daily exposure to UV-A.
Title: The isolation of prophyra-334 from marine algae and its UV-absorption behavior
Author/s: Zhang Zhaohui, Gao Xin, Yuri Tashiro, Shingo Matsukawa, Hiroo Ogawa
Abstract:
Prophyra-334 was prepared by methanol extraction and HPLC methods from
marine algae (dried laver). It is a sunscreen compound that has good absorption of
ultraviolet radiations in the wavelength ranges of 200–400 nm. The absorption
maximum wavelength of prophyra-334 is at 334 nm, so defined the name. The molar
extinction coefficient (ε) of prophyra-334 in aqueous solution at 334 nm wavelength is
4.23×104. The absorption of prophyra-334 in organic solvents differs in aqueous
solutions. In polar organic solvents, the absorption maximum wavelength of prophyra-
334 has a slight shift toward longer wavelength compared with that in pure water. On
the contrary, in inert non-polar organic solvents, the absorption maximum wavelength
and the shape of absorption spectra of prophyra-334 are changed. The effects of
organic solvents on prophyra-334 stability suggested that: (1) the absorbance of
prophyra-334 in water is generally constant at temperature of 60°C in 24 h, meaning
that prophyra-334 is quite stable in water; (2) the absorbance of prophyra-334 in
ethanol and hexane decreases at the same condition. The stability of prophyra-334 in
organic solvents is less than that in aqueous solution. In benzene, the prophyra-334 is
very instable.