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Power and Data 08-16-12 Final Color
Power and Data 08-16-12 Final Color
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Alexander Rush
Illinois Institute of Technology
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Abstract—A wireless cortical neural recording system with Sending raw neural data from the implant allows one to
a miniature implanted package is needed in a variety of flexibly change the spike sorting/spike detection algorithms
neuroscience and biomedical applications. Toward that end we in extracorporeal-based software, but comes at the expense
have developed a transcutaneous two-way communication and of high data rate requirements. To send raw neural data from
power system for wireless neural recording. Wireless powering
16 channels, assuming an ADC resolution of 8bits/sample
and forward data transmission (into the body) at 1.25Mbps is
achieved using an FSK modulated Class E converter. The and a sampling rate of 20kSamples/s, a reverse telemetry
reverse telemetry (out of the body) carrier frequency is data rate of at least 2.56Mbps would be required.
generated using an Integer-N PLL providing the necessary
wide-band data link to support simultaneous reverse telemetry To avoid the bandwidth limitations of an LSK system, it
from multiple implanted devices on separate channels. Each is necessary to have another link for reverse telemetry. This
channel is designed to support reverse telemetry with a data second link can use radiated emissions, optical coupling, or
rate in excess of 3Mbps, which is sufficient for our goal of inductive coupling to send data out of the body. For our
streaming 16 channels of raw neural data. We plan to design, we chose to use an inductive link for reverse
incorporate this implantable power and telemetry system in a telemetry.
1cm diameter single-site cortical neural recording implant.
I. INTRODUCTION
any neuroscience researchers as well as emerging
M prosthesis designs remain limited by the unavailability
of wideband transcutaneous wireless neural recording.
In the case of neuroscience research on animal subjects, an
advantage of wireless neural recording is to remove the
effect of tethering on the animal’s behavior. For neural
prosthesis design, wireless recording has the advantage of
reducing the risk of infection as well as device breakage.
A wireless neural recording system requires power and
forward data to be transferred to the implant, and neural
recording data to be transmitted from the implant. Both
power and forward data can be implemented on a single
inductive link, with forward data encoded as modulation of
the power carrier. Reverse telemetry can be achieved on the
same link by a method called load shift keying (LSK), but
the data rate is generally limited to a fraction of the power
carrier frequency, which is typically in the low MHz range. Figure 1. (a) Schematic of bidirectional data transfer system (b) Physical
Furthermore, if multiple implants are powered by the diagram of dual inductive link coils modified from [1]
external power coil, an external controller must time-
division multiplex (TDM) the reverse telemetry from the Ideally the implant would have a single-site, or “button”
implants. geometry [2], which would simplify implantation, and
prevent potential complications resulting from tethering
between multiple sections of the implant. For all wireless
neural recording implants with multiple sections of which
the authors are aware, one section resides on the skull or in a
Manuscript received February 15, 2012. This work was supported by
private donations to the Illinois Institute of Technology. bone-seat and is tethered to the microelectrode array inserted
A. Rush is with the Illinois institute of Technology, Chicago, IL 60616 in the cortex. An increased foreign body response has been
USA (e-mail: rushale@iit.edu). observed in brain tissue to implants tethered to the skull
P. R. Troyk, is with Illinois institute of Technology, Chicago, IL 60616
USA (e-mail: troyk@iit.edu).
[3,4]. Another possible complication is that the tethering
connection between multiple sections of the implant can fail transfer to the implant is achieved by generating a large AC
due to wire breakage or deinsulation [5,6]. current in Coil 1 using a Class E converter. AC current is
induced in Coil 2, which is proportional to the coupling
To achieve a single-site geometry for a dual inductive
coefficient between the external and implanted power coils,
link, the power and data link must operate in the same
k12. The resulting AC voltage is rectified to supply the
volume-space. This necessitates the consideration of
application-specific integrated circuit (ASIC) with power
magnetic interactions between the power and data coils,
and is also used to generate a reference clock for the ASIC.
because destructive paths of the reverse telemetry signal (out
Forward data transfer is achieved by FSK modulation of the
of phase with the constructive paths) can greatly reduce the
5MHz power carrier at a data rate of 1.25Mbps in order to
amplitude of the signal received by the external data coil.
send control data to the ASIC.
This approach was reported by [7] for the design of a dual
In the ASIC circuitry, the reference clock, derived from
inductive link for power and forward data transmission for a
the 5MHz power carrier, is multiplied up by an integer-N
retinal prosthesis.
PLL to generate a reverse telemetry carrier between 50MHz
Design of both the power and data inductive links can be and 100MHz. The reverse telemetry is either amplitude-
facilitated with the help of an analytic model of the inductive shift keying (ASK) or binary phase-shift keying (BPSK)
link electrical and performance parameters in terms of the modulated. On-chip driver circuitry induces current in Coil
link physical parameters [8-10]. This allows the physical 4 to generate the reverse telemetry signal. According to
parameters to be iterated on a computer rather than on the simulation in PSpice A/D via OrCAD Capture CIS
bench to find the optimal design within the physical (Cadence Design Systems, San Jose, CA), with a power
restriction imposed. An analytic model of the link was used supply of 3V, the driver circuitry can drive 2.5mA peak-to-
here to find the data coil radius which maximizes the peak current in Coil 4.
effective coupling coefficient between the data coils, taking Data is received by one of the two external differential
into account the contributions of the constructive and
data coils, Coil 3. A differential coil configuration is used to
destructive reverse telemetry coupling paths between the
cancel both the large power signal at its fundamental
data coils.
frequency and harmonics generated by the Class E converter
It is highly beneficial to lock the reverse telemetry carrier that fall within the frequency range of the reverse telemetry.
to a multiple of the power carrier frequency using a phase-
locked loop (PLL). This provides a convenient method for III. ANALYTIC MODEL
supporting simultaneous reverse telemetry from multiple In order to avoid time-consuming design iterations on the
implants powered by the same magnetic field. One can bench, the dual coil link for power and reverse telemetry,
simply assign a different frequency division ratio to each illustrated in Fig. 1a,b, can be optimized with an algorithm
implant. This method can also simplify demodulation of the which iterates the modifiable link parameters and chooses an
reverse telemetry, because one can derive the reverse appropriate combination of physical parameters which are
telemetry carrier from the power carrier frequency. associated with the best performance, as predicted by an
Therefore, we have incorporated an Integer-N PLL into our analytic model of the link.
integrated circuit design, which can generate outputs of 50,
This algorithm uses an expression similar to that
60, 70, 80, 90, and 100MHz, from the 5MHz power carrier.
presented in [7] for a dual coil system to provide power and
The PLL cell design consumes less than 1.3mW below
forward telemetry to a retinal prosthesis. The expression
100MHz, uses self-biasing techniques for supply rejection,
and has dimensions of 350um x 680um. was adapted for a dual coil system to provide power and
reverse telemetry. The variables used for the electrical
Fig. 1 shows a schematic of our power and bidirectional parameters of the link are the same as illustrated in Fig. 1a.
data transfer system. In this paper we present, our dual The derivation is similar to [7], and space does not allow
inductive link design methodology, implant and external it to be included here. The assumptions critical to the
circuitry design, as well as simulation and measurement derivation of the simplified equation for data magnitude, (1),
results. Portions of this work have been previously are high quality factor coils and that the power coils are
presented in conference form [1,11,12]. effectively short-circuited at the data carrier frequency (e.g.,
by a parallel capacitance). This expression for the
II. SYSTEM IMPLEMENTATION magnitude of the reverse telemetry signal received by the
The physical arrangement of the coils is illustrated in Fig. external data coil, V3, shown in Fig. 1a is
1(b). For a typical implanted device, Coil 1 (L1) would be V3 I 4 jdatakeff L3 L4 (1)
the external power coil, Coil 2 (L2) would be the implanted
power coil, Coil 3 (L3) would be one of the external k eff k34 k 24k 23 k14k13 k14k12k 23 k 24k12k13
differential data coils, and Coil 4 (L4) would be the
implanted data coil and is concentric to Coil 2. Power
where I4 is the current induced in the implant data coil by chose 8mm as the optimal diameter for Coil 4 for the 10mm
the coil driver circuitry, data is the angular frequency of the diameter of Coil 2 assumed.
In order to test the analytic model, we measured V3 as a
reverse telemetry carrier, and L3, L4, k12, k13, etc. are as
function of separation, and compared the measured values to
indicated in Fig. 1a. V3 and I4 are in phasor notation, so the
the values calculated with (1) and the equations for self and
‘j’ in (1) indicates that the steady state sinusoidal voltage on
mutual inductance as a function of the link physical
Coil 3 leads the inverse of a sinusoidal current in Coil 4 by
parameters. Again, the parameters listed in Table I were
90 degrees. According to (1), the data link can be optimized
assumed, and Coil 4 was made with a diameter of 8mm. As
by maximizing the effective coupling coefficient, keff. By
shown in Fig. 3, the measured values closely match the
analyzing the dual coil link with this equation for k eff, we
calculated values. These measurements were made with a
found that the optimal ratio of implanted power and data coil
test board designed to minimize parasitics, and a custom
radii for our design was close to 0.8.
XYZ positioning system, which has been fabricated for
To raise confidence in this idealized expression for the
testing inductive link systems in our laboratory. This XYZ
effective coupling coefficient between the data coils given in
positioning system consists of three manual linear actuators
(1) as a performance metric, we compared values of V 3
fastened together. Each linear positioner has a millimeter
simulated in PSpice A/D via OrCAD Capture CIS (Cadence
scale for accurate measurement.
Design Systems, San Jose, CA) including non-ideal,
parasitic coil parameters (effective series resistance and self-
capacitance) to values of V3 calculated using the idealized
equation (1) for ten values of implanted data coil radius,
fixing all other physical parameters. The non-ideal coil
parameters used for simulation, were calculated using our
analytic model for these parameters, presented in [1], which
space does not allow to be included here. The physical
parameters which were assumed for the data presented in
Fig. 2, while the radius of the implanted data coil was
varied, are summarized in Table I. The current in the data
coil was modeled as a sinusoid with a peak amplitude of
1mA, and coil separation was set to 1cm.
V. CLASS E CONVERTER
The magnetic field for inductive powering was generated Figure 5. Methods of filtering Class E harmonics from the series LC
branch of the Class E tank circuit (a) Low-pass filter in the series tank
by a Class-E converter transmitter operating at 5MHz. The circuit (b) Notch-filter in series tank circuit [11].
transmitter coil carried a peak current of 0.65A, had a radius
of 3cm and 8 turns of 2MHz litz wire (New England Wire VI. DIFFERENTIAL ANTENNA
Corporation, Lisbon, NH).
The external data receiver chosen was a pair of “bucked”
Due to the large size of the power signal compared to the
coils connected in parallel and anti-phase. In other words
reverse telemetry signal, even small amounts of harmonic
the inner leads were connected together and outer leads were
distortion, occurring at integer multiples of the power carrier
connected together and grounded. This has the effect of
frequency, can obscure the reverse telemetry signal.
canceling both distant sources of RF magnetic interference
Another source of interference can be the transmitter gate
as well as nulling the 5MHz power carrier provided that the
drive, which can couple to the external data coil from the
bucked coils are carefully aligned with Coil 1. The receiver
gate-drain capacitance of the Class-E field-effect transistor
coils could have been connected in series, in what is known
(FET). Harmonic distortion resulting from normal operation
as a “figure-8” configuration. However, we found that this
of the Class-E converter and from the gate drive signal is
made our receiver front-end susceptible to noise and
illustrated in Fig. 4.
feedback. Therefore, we used the parallel coil configuration.
However, this required that we place a high-pass filter in
series with each of the bucked coils to minimize induced
power-carrier current which would have loaded the
transmitter and reduced the powering magnetic field at the
implant. A photograph of the differential reverse telemetry
receiver antenna is shown in Fig. 6.
The detection of the reverse telemetry data signal is
maximal at the center of either of the bucked coils and very
small at the shared edge of the bucked coils. The
cancellation of harmonics generated by the Class E
converter, which fall within the bandwidth of the reverse
telemetry signal, is illustrated in Fig. 7.
INI System, U of Utah and Yes, Button (Single- Radiated, ISM Band
Inductive Spike Detection 157kbps 3185pJ/b
Stanford [17] Site) Geometry 902-928MHz
Radiated, Impulse
Yes, At Least Two Raw Neural
UCSC System [19] Battery radio based UWB, 90Mbps 17.78pJ/b
Site Geometry Recording
4GHz
TABLE III
and data link with a distance of 20mm and a data rate of
In simulation, the PLL power consumption was below 3Mbps is given in Fig. 10.
1.3mW for frequencies below 100MHz with a 3V supply.
The power consumption of the fabricated ASIC was
measured to be 4.2mW operating at 48MHz with a 2.7V
supply, and the measured power consumption closely
matched OrCAD simulations. Simulations predict that the
PLL consumes only 14% of the total power, while the
reverse telemetry driver consumes 74% of the total power.
The reverse telemetry driver circuitry included on the chip is
not optimized for low power because it has redundant
modulation and driver circuitry that was used for evaluation
purposes.
Figure 12. Simplified block diagram of the DSP filtering and data
synchronization system used to demodulate reverse telemetry from the
prototype four channel WNRA circuitry.