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    Yeyen Saputri
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    Older age, neutrophilia, and elevated lactate dehydrogenase and D-dimer levels increase the risks of developing acute respiratory distress syndrome (ARDS) and death from COVID-19. Up to 22% of ICU patients experience cardiac injury evidenced by increased troponin levels, and up to 12% of patients without known cardiovascular disease experience elevated troponin levels or cardiac arrest. COVID-19 is diagnosed using a real-time reverse transcription–polymerase chain reaction assay on respiratory and serum samples, though upper respiratory tract specimens may contain a lower viral load than lower respiratory tract specimens, so retesting using lower respiratory tract specimens is recommended if upper tests are negative but clinical suspicion remains. Common laboratory findings in COVID-19 patients include

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    Older age, neutrophilia, and elevated lactate dehydrogenase and D-dimer levels increase the risks of developing acute respiratory distress syndrome (ARDS) and death from COVID-19. Up to 22% of ICU patients experience cardiac injury evidenced by increased troponin levels, and up to 12% of patients without known cardiovascular disease experience elevated troponin levels or cardiac arrest. COVID-19 is diagnosed using a real-time reverse transcription–polymerase chain reaction assay on respiratory and serum samples, though upper respiratory tract specimens may contain a lower viral load than lower respiratory tract specimens, so retesting using lower respiratory tract specimens is recommended if upper tests are negative but clinical suspicion remains. Common laboratory findings in COVID-19 patients include

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    5 views1 page

    Komplikasi

    Uploaded by

    Yeyen Saputri
    Older age, neutrophilia, and elevated lactate dehydrogenase and D-dimer levels increase the risks of developing acute respiratory distress syndrome (ARDS) and death from COVID-19. Up to 22% of ICU patients experience cardiac injury evidenced by increased troponin levels, and up to 12% of patients without known cardiovascular disease experience elevated troponin levels or cardiac arrest. COVID-19 is diagnosed using a real-time reverse transcription–polymerase chain reaction assay on respiratory and serum samples, though upper respiratory tract specimens may contain a lower viral load than lower respiratory tract specimens, so retesting using lower respiratory tract specimens is recommended if upper tests are negative but clinical suspicion remains. Common laboratory findings in COVID-19 patients include

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    Komplikasi:

    Acute respiratory distress syndrome

    older age, neutrophilia, and elevated lactate dehydrogenase and D-dimer levels
    increased the risks of ARDS and death

    Cardiac concerns

    The risk of cardiac injury, evidenced by increased troponin levels, was up


    to 22% in ICU patients. Interestingly, up to 12% of patients without known
    cardiovascular disease had elevated troponin levels or experienced cardiac
    arrest during hospitalization for COVID-19. The pathophysiology of injury is
    under investigation, but some presentations seem related to cytokine
    storm.

    Diagnostics

    The test is a real-time reverse transcription–polymerase chain reaction


    (rRT-PCR) assay that can be used to diagnose the virus in respiratory and
    serum samples from clinical specimens

    Upper respiratory tract specimens have been reported to contain a smaller


    viral load than lower respiratory tract specimens do. If PCR tests are
    negative for SARS-CoV-2 using upper respiratory tract specimens despite
    persistent clinical suspicion, the WHO recommends retesting using lower
    respiratory tract specimens

    Laboratory findings in patients with COVID-19


    Leukopenia, leukocytosis, and lymphopenia were common among early cases. [32, 72] 
    Lactate dehydrogenase and ferritin levels are commonly elevated

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