Orrtholosy mlaled
@® Phas 4 Gaoln'e +. Sean keions
ie Seentn ( Oak Seemke
Kequtakin yf Objeckw
@ ky Ganbve Aud it) @ Compestien 9 Gaslre
@® Mechamism 9
~ HU Seanekin
Sec
Type 4g glends q
@ Oxyntie glenda (qssbete gerd» 3
+ Seemtes HU, peperne en, inkrimate Jachor and mucus.
+ Located om the imgide surfaces g bods » Facdus
Pronima “gor.
Surface
epithelium
Deentiens +
wD Mucus meck cell 7 muces
® Pepe [Chis{ cel = Fepsinegen
@ Parvekot [dxpak ec eel 2H >
Imtaansie factor
tbo Pylowte glands :
+ Mosmby seanke mucus , dbo qaskmin
+ Locate tm Antrat borker 9 Stomach, dies
‘Mucous neck
cells
Oxyntic
(parietal)
cells
Peptic
Types 4 cell pooenk 5
Mucus meck cells = mus
Pepte edi = Fepeimogen
B® G cells s GoskeinSurface Maco Call +
+ Entire sen face 5 slomach
cmucosa bekween Lames
has 0 combim cious wi
speffal red ne 4 coms
cdl called “Suva
Mucows) Celt.
* Coal stomach surface \
ABRHEHER, » by Pera sym galbve
~ Stimulates HCL seerkim by porvekal cells
~ Also Fepef neyen Fem Peptre cell.
+ ARSHEMIRE 2 by ECL (Enberochwom af fin- Uke cell’)
~ Shindatey Ha seek -
w ECL Theelf Ge skinwated by Gashin
Gaskrinl> ~ 4 Gashtn cela (4 -cell)
ne Law ge pelypepkde (4-34 , G1)
ue
oP
~ Skemulakes the HO seeker:@ Forma leon 4 chrme iahibils
jobere Seerbiom, by Reverse
My enten’c Nevvow Syphon — Exhibic
sympathebee 2 Vow
Tabibileen 7 Gaobre Se
® Poorenee | Aud, fat, wo ben breakdoun ducks mm
upper small im woke — Secebin r geabebls Gaolnc
Secernkim -
@ Other Eager +O Glucose -dependent imsulmo tropre
epkde
(Gastr'e Shir bo fois /
UD Vascackn In tulenal Tolypephede
{itd Sematoskatin .
Al ued, imbubit Geol Secreleen -
[Gr Hormones Site of Secretion Primary Sinai
Gann ‘Grails antrum ofstomach | Stich peptides and amino acids
‘ddd ‘vagus hough
‘Seortin Seallsofthe duodenum | Acai chyme
x Teeliof the daodenumand | Small popes and amino aad fats lle and vlanes sphincter
‘eunum
‘Gaticinhiory | Duedenumandjeunam | Fatly acids glo, amino as
‘eptie o GIP
‘oti
Peptide Ya ac1. High acid and pepsin content
2 lea
83, Poor blood supply
4 Poor secretion of mucus
5. Infection (H. pyr!)
Backerum Helicobacker pylon
breaks down ‘he Guakoduclonad
Muwsel Barter aug skmutate
Goalnc Aud Seer bin -
+ Other Comes
& Smokin
(+ Two ssicheiace Hi cules ®& Conbunep tte 4 Aleohe
abi on
He xcers ive Add “ @ Camumpkn 9 Aspirin and
Nervous flex & Hormonal Other pomstemtde anbr-
feedback fom duodenum Enjtamimaben dnp (N sAlbs)
GB Prrence q Aud fn duedenum
Uberely Seer ken fem imberbnel
mmuwsd. Pancrnan skimvates and secretes hos for
mneu Weal'sabion
‘Treatment of Pept Veer
Sins th dconrythat och ppti uration an kc assy the cera pr herp hang mercy, Alot of pte’
‘wth poptculewration can be bes oy oe
"Wet of enh slon with tr gens oil ines aces
2 administration ofan aid suppress’ du such 36 which are aniistaminic agent that blocks the
iat toto stare pre lod histamine meeps acing gore a sertion y 1-0 Mere eet Proton
odin, ch aon and marie ma ewe pred eB,
tha can be ue ott pps inde the flowing
ssid with tacky however, the method sma sed fen recy.
pounds re ued thal pathy enhance the muceel are and ae asco
£:Chtopectve apts shes sulin oe slam noms sues otal open fp wth the hesing fhe ker posi by
forming protetve contig
stoProntagfansin slopes such = RERan be wad to ede the inden of peptic ules inpatients ho anon ong NSAID
(5: Oiher conservative mesures uch 2 quitng smoking educon inane and alshlconsampton and mess to reduce tess can
‘postu the healing pcs ad prevent er fo ecg =
Pylorus: