USKUDAR UNIVERSITY

Department of Bioengineering (English)

BEN 520 - FUNDAMENTALS OF BIOENGINEERING 2
MIDTERM EXAM
DURATION: 120 MIN
2
8.04.2022

Name, Surname: Signature:

Student ID:

1. Acetaminophen (C8H9NO2), commercially known as Tylenol©, is a drug widely used to

alleviate pain and inflammatory symptoms. A single Tylenol © tablet contains 325 mg of
acetaminophen. Calculate the mole and mass fraction of each element (C, H, N, and O) in the
tablet. (25 p)

1
2. The trachea has a diameter of 18 mm; air flows through it at a linear velocity of 80 cm/s. Each
small bronchus has a diameter of 1.3 mm; air flows through the small bronchi at a linear
velocity of 15 cm/s. Calculate the volumetric flow rate, mass flow rate, and molar flow rate of
air through each of these regions of the respiratory system. Also, calculate the Reynolds
number for each compartment, given the formula:

where D is diameter, v is linear velocity, r is density, and m is viscosity. The viscosity of air is
1.84 * 10-4 g/(cm.s). (25 p)

2
3
3. Stomachs produce gastric acid to aid in digestion. This acid is mainly composed of
hydrochloric acid that is secreted by cells of the stomach lining called parietal cells. Excessive
secretion of this acid is common and can lead to many stomach problems such as gastritis,
gastric ulcers, and peptic acid disease. These disorders are treated with antacid tablets, which
contain weak bases that can help neutralize acids. A common antacid tablet contains the weak
base magnesium hydroxide, Mg(OH) 2. The neutralization reaction for stomach hydrochloric
acid (HCI) is:

Mg(OH)2 + 2HCI → MgCl2 + 2H2O

a) Draw system and label it. (4 p)

b) Is it an open or closed system? Why? (4 p)
c) Is it a steady state system or dynamic state? Why? (4 p)
d) Is there a reaction or no reaction? (4 p)
e) What are the conservation equations? (5 p)
f) What are the accounting equations needed? (4 p)

4
5
4. Corn-steep liquor contains 2.5 wt% dextrose and 50 wt% water; the rest of the liquor stream is
solids. Beet molasses contains 50 wt% sucrose, 1.0 wt% dextrose, and 18 wt% water; the rest
of the molasses stream contains solids. Beet molasses is mixed with corn-steep liquor and
water in a mixing tank to produce a dilute sugar mixture. The exit stream contains 2.0 wt%
dextrose and 12.6 wt% sucrose and is ready to be fed into a fermentation unit. See Figure at
below.
a) Draw a diagram of the system and label entering and exiting streams. (5 p)
b) What is the basis in your solution to this problem? What are the weight percents (wt%) of
dextrose, sucrose, solids, and water in the exit stream? (10 p)
c) What is the ratio of the mass flow rate of the water stream to the mass flow rate of the corn-
steep liquor stream? (10 p)

6
7
8
9