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DRUG STUDY Format NSG
DRUG STUDY Format NSG
DRUG STUDY Format NSG
DRUG STUDY
Name of Drug Dosage, Route, Mechanism of Action Indication Adverse Reactions Special Precautions Nursing Responsibilities
Frequency and
Timing
-highly emetogenic cancer
chemotherapy, including cisplatin
Serotonin Syndrome -Rash, itching,
-symptoms include: mental
Generic: Ondansetron blocks the greater than or equal to 50 mg\m2, status changes, autonomic
hoarseness, trouble -The nurse will administer
Ondansetron actions of chemicals in initial and repeat courses of
instability (i.e. trachycardia, breathing, trouble Zofran as ordered
moderately emetogenic cancer
hydrochloride the body that can trigger chemotherapy, radiotherapy in fluctuating blood pressure) swallowing, or any -The nurse will assess the
4mg IV push every 6 nausea and patients receiving either total body and neuromuscular swelling of hands, face, patients nausea every 2-3 hours.
irradiation, single high-dose symptoms (i.e. tremors) or mouth
Brand: hours for nausea and vomiting,Ondansetron is fraction to the abdomen, or daily -most reports associated with -The nurse will provide the
Zofran vomiting used to prevent nausea fractions to the abdomen. combined use of Zofran and patient with clear liquids to
Ondansetron tablets are also other senotonetric drugs like -do not use if receiving
and vomiting that maybe indicated for the prevention of anti-depressants apomorphine consume.
caused by surgery,cancer postoperative nausea and\or
vomiting.
-The nurse will educate the
chemotherapy or patient on 5 foods or liquids to
Classification radiation treatment. Contraindication Side Effects avoid that makes nausea worst.
-The nurse will verbalize 4
-hypersensitivity (e.g,, Drowsiness techniques on how to reduce
Anitemetics/May anapylasis) to ondansetron Headache
nausea.
block 5-Ht, in the or any of the components of Weakness
the formulation, receiving Dry mouth
chemoreceptor trigger concomitant apomorphine A rash may occur
zone and in the due to the risk of profound in 1% of patients
peripheral nervous hypotension and loss of Patient receiving
system on nerve consciousness. ondansetron
terminals of the vagus (Zofran) ODT on a
nerve. continued basis
may reprt
constipation