Pathology of Respiratory

Diseases
Practical I, For Second Year Medical
Students
Respiratory-Renal Block
I- SLides
1) Rhinoscleroma, slide.
 Microscopic picture:
This is a histological section from nasal mucosa with atrophic covering
epithelium. The sub epithelial layer is infiltrated by a granulomatous
reaction formed of (1)Mikulicz cells are large cells with pale to clear
cytoplasm and small rounded nuclei. These cells represent macrophages
with hydropic degeneration, and they are pathognomonic to the disease.
(2) Russell bodies: are homogenous pink bodies representing hyaline
degeneration of plasma cells.

In between such Mikulicz cells and Russell bodies, there are chronic
inflammatory cells mainly lymphocytes, plasma cells and fibroblasts.
 2) Slide (R-3): Chronic
fibrocaseous pulmonary T.B.
3) Slide (R-6): Emphysema, lung.
II- Jars &Photos
1) Lobar pneumonia, grey
hepatization.
Photo no. R2.
Jar no. R2a.
 Cause Complications

Droplet infection by pneumococci from a patient or a carrier 1-Lung abscess

lung fibrosis

Local spread of infection causes empyema

2) Bronchiectasis
Jars no. R3a
 Complications
Causes

Lung abscess
Bronchial infection:

Bronchial obstruction: By mucous plugs, foreign bodies Local spread of infection causes empyema

Congenital abnormality Haemoptysis

·
3) Pulmonary Tuberculosis

photo No. R4.

 Causes Complications

Meningitis
by inhalation of human T.B. bacilli
Hepatitis

Pott’s disease
4) Bronchogenic carcinoma:
photo R5
 Causes Complications

Somking
Bronchial obstruction
Air pollution

Hemoptysis
Radiation

Emphysema
5) Laryngeal carcinoma

R6
Thank you