Scribd Logo
Upload

Welcome to Scribd!

  • 12 views

    Staphylococcus

    Uploaded by

    Zeth Moturi
    Staphylococcus are major bacterial pathogens that can be categorized based on their gram staining and cellular structure. The medically important genera include Staphylococcus, Streptococcus, and Enterococcus. Staphylococcus aureus is the most common cause of staph infections and can be identified based on its production of coagulase and golden pigmented colonies, while S. epidermidis does not produce coagulase and forms white colonies. Treatment depends on identifying the specific species and determining antibiotic resistance profiles.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content

    You might also like

    Staphylococcus

    Uploaded by

    Zeth Moturi
    12 views13 pages
    Staphylococcus are major bacterial pathogens that can be categorized based on their gram staining and cellular structure. The medically important genera include Staphylococcus, Streptococcus, and Enterococcus. Staphylococcus aureus is the most common cause of staph infections and can be identified based on its production of coagulase and golden pigmented colonies, while S. epidermidis does not produce coagulase and forms white colonies. Treatment depends on identifying the specific species and determining antibiotic resistance profiles.

    Original Description:

    Original Title

    Untitled

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Staphylococcus are major bacterial pathogens that can be categorized based on their gram staining and cellular structure. The medically important genera include Staphylococcus, Streptococcus, and Enterococcus. Staphylococcus aureus is the most common cause of staph infections and can be identified based on its production of coagulase and golden pigmented colonies, while S. epidermidis does not produce coagulase and forms white colonies. Treatment depends on identifying the specific species and determining antibiotic resistance profiles.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    12 views13 pages

    Staphylococcus

    Uploaded by

    Zeth Moturi
    Staphylococcus are major bacterial pathogens that can be categorized based on their gram staining and cellular structure. The medically important genera include Staphylococcus, Streptococcus, and Enterococcus. Staphylococcus aureus is the most common cause of staph infections and can be identified based on its production of coagulase and golden pigmented colonies, while S. epidermidis does not produce coagulase and forms white colonies. Treatment depends on identifying the specific species and determining antibiotic resistance profiles.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 13

    Staphylococcus

    Major Bacterial
    Pathogens

    Type of Organism Genus

    Readily Gram Stained

    Gram-Positive Cocci Staphylococcus, Streptococcus, Enterococcus


    Gram-Negative Cocci Neisseria
    Gram-Positive Rods Corynebacterium, Listeria, Bacillus, Clostridium, Actinomyces, Nocardia
    Gram-Negative Rods Enteric / Respiratory Tract Organisms / Organisms from Animal Source

    Not Readily Gram Stained


    Mycobacterium, Mycoplasma, Treponema, Leptospira
    Not Obligate Intra-
    cellular Parasites

    Obligate Intra- cellular Chlamydia, Rickettsia


    Parasites
    Medically Important
    Genera

    Non-Motile
    Don’t Form Spores
    Gram positive Cocci

    Staphylococcus Streptococcus
    Grapelike Cluster Chains

    Catalase Don’t Produce Catalase

    Catalase
    What? 2H2O2 2H2O + O2

    Why? Survive Killing Effect of H2O2


    Types / Properties
    of Staphylococcus

    Fibrinogen Fibrin

    Thrombin

    Staphylococcus Staphylococcus Staphylococcus


    Prothrombin
    aureus epidermidis saprophyticus

    Coagulase + - -

    Colonies Golden White White

    Hemolysins + - -
    Activate
    Cell wall Complement System Adherence
    Components Plasma
    Membrane Peptidoglycan Teichoic Acid

    Reduced
    Phagocytosis of
    C3b Bacteria

    Capsule
    Complement System
    IgG Inactivation

    PBP
    Nafcillin NRSA Virulence
    Factor

    IL-1 / IL-2 Lipoteichoic


    MRSA Protein A B-Lactamase
    Methicillin TNF Acid
    Septic Shock

    Degrades B-
    Lactam Ring
    S. aureus
    Diseases
    Abscess

    S. epidermidis Pyogenic Infections

    Food Poisoning

    Infection of Scalded Skin Syndrome


    S. saprophyticus
    Prosthetic Heart Toxic Shock Syndrome
    valves / Hips HAP
    Urinary Tract Infection
    Septicaemia
    Surgical Wound Infection
    Member of Skin
    Folliculitis, Cellulitis,
    Flora
    Impetigo

    Conjuctivitis
    Transmission

    Human

    Nose Immuno-
    Compromised
    Hands
    Vagina Diabetes / IV
    Drugs
    Lesions
    Towel CGD
    S . epidermidis
    Pathogenesis Staphylococcus
    aureus
    Enterotoxin Exfoliatin

    TSST

    Protease
    IL-1 IL-1
    IL-2 IL-2
    Desmoglein
    IL-2 IL-1

    IL-1 IL-2 Blood Steam

    Enteric Nervous System


    IL-2 TNF
    IL-1 IL-2
    Desmosome
    IL-1 TNF

    Vomiting Center
    Toxemia
    Coagulase Exotoxins

    Coagulase
    Clot Plasma Alpha-Toxin P-V Leukocidin
    Fibrinolysin
    Hyaluronidase
    Hole in Cell Damaging Cell
    Proteases Wall off Infected Site Membrane Membrane
    Nucleases
    Lipases
    Neutrophils Migration
    Loss of LMW Sub WBC

    S . epidermidis S . saprophyticus

    Infection of Prosthetic Heart


    valves / Hips Joints UTI Infection
    Treatment Methicillin /
    Nafcillin Resistant

    Vancomycin + Gentamycin
    Penicillin G Resistant Daptomycin
    Toxic Shock Syndrome
    Trimethoprim-Sulfamethoxazole
    Nafcillin / Cloxacillin Fluids / Inotropic Drugs
    Clindamycin
    Cephalosporins / Vancomycin Nafcillin
    Tampon Removal
    Amoxicillin + Clavulanic Acid
    Pooled Serum Globulins

    S. Epidermidis Skin Infections


    UTI Infections
    Vancomycin Mupirocin + Chlorhexidine
    + Trimethoprim-
    Rifampin Sulfamethoxazole Skin Abscess
    + Quinoline
    Aminoglycoside Incision / Drainage
    Lab Diagnosis Toxic Shock Syndrome
    TSST
    Novobiocin

    Staphylococcus Staphylococcus Staphylococcus


    aureus epidermidis saprophyticus

    Coagulase + - -

    Colonies Golden White White

    Hemolysins + - -
    Prevention
    Watch Anytime, Anywhere!
    Stream videos on your device, cast to your TV, or listen in the background.
    Download our Android / iOS App & Start Learning Today!

    You might also like