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D H A N M I S T R Y - C O M: Inorganic Elements and Their Biological Functions Bulk Metals Trace Metals Na, K
D H A N M I S T R Y - C O M: Inorganic Elements and Their Biological Functions Bulk Metals Trace Metals Na, K
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t * Selenium sulfide used to treat seborrheic dermatitis and Tinea versicolor.
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t * MoS 2-
(tetrathiomolybdate) is used as “anti copper agent” in Wilson’s disease (excess of copper
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s accumulation in liver - a genetic disorder). It is also used as an antitumor agent.
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u Inorganic elements and their biological functions
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e Bulk metals - Na, K, Mg, Ca
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m Trace metals - Zn, Fe, Co, Ni, Cu, Mo, V - metals with low conc. are used for biocatalysis.
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k * Na+,K+:
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o As electrolytes, maintain the concentration gradient (osmotic balance). a
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b Helps in active and passive transport.
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h Charge carriers.
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* Mg : Present in chlorophyll.
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a In energy production (ATP --->ADP);
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Activation of enzymes.
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Information carrier;
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w Present in endo and exo skeletons.
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s * Ca2+: Charge carrier.
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V A
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t In muscle and nerve functions - cell signalling. It acts as second messenger and sentinel at hem
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b Present in teeth as Ca (PO ) (OH) (hydroxylapatite), and CaCO ,
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v Present in endo and exo skeletons; oc
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e In activation of enzymes;
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a In blood coagulation.
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e VIV/V, MoIV/VI, W IV/VI, Mn II/III/IV, Fe II/III, Ni I/II/III, Cu I/II
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a * : electron transfer
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p * Fe and Cu: Transport and storage of dioxygen.
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d Fe3O4 is used to store iron, and, as it is magnetic, is used by ‘magnetotactic’ bacteria to
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a sense the direction of the Earth’s magnetic field.
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m * Co: Cobalamine, e.g. Vitamin-B
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f * Mn: In photosynthesis, generation of dioxygen by splitting water. Mn is part of OEC (Oxygen
h Evolving Complex) in PS II.
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