Psoriasis

Topical 1) Steroids. Side effects of steroids

2) Vit-D analogue. ➔ Skin atrophy,
3) Tazarotene (Retinoid) hypopigmentation,
4) Calcineurin inhibitor striae.
Systemic 1) Phototherapy ➔ NOTE ➔ NEVER USE
nbUVB, BBUVB, PUVA. SYSTEMIC STEROIDS IT
2) MTX 7.5 to 25 mg. WILL CAUSE PUSTULAR
3) Acitretin. PSORIASIS.
4) Cyclosporine 2.5 to
5mg.
5) Azathioprine 50 to 100
mg.
6) Biologics ➔ Etanercept,
Adalimumab, infliximab,
Ustekinumab,
Secukinumab.
Lichen Planus
Topical 1) Steroids (or
intralesional).
Systemic 1) Steroids.
2) Acitretin.
3) NBUVB.
4) Cyclosporine,
Metronidazole,
Mycophenolate.
Pityriasis Rosea
Main line Reassurance, moisturisers.
Topical Antipruritic lotions or low For symptomatic relief.
to moderate strength
steroids.
Systemic 1) UVB. Severe cases only.
2) Antihistamine.
3) Steriods (Rarely
required).
Acne
Topical 1) Retinoids (tretinoin,
adaplene, tazarotene).
2) Benzoyl peroxide.
3) Antibiotics
(Clindamycin,
Erythromycin).
 4) Azelaic acid.
Systemic 1) Antibiotics Indications of anti
(Doxycycline, androgens :
Erythromycin). -PCOS.
2) Anti-androgen -Late onset in women.
(Cyproterone acetate). -Acne at lower face and
3) Sprionolactone 50- neck, premenstrual flare.
100mg. -Resistant acne.
4) Isotretinoin (MUST BE
WRITTEN) 0.5mg/kg then
1mg/kg or cumulative
dose 120-150 mg/kg
Surgical 1) Comedo extraction.
2) Chemical peels.
3) Laser resurfacing,
deeper chemical peels,
filler substances for scars.
Alopecia Areata
General Correction of predisposing
factors ➔ Stress,
Infections,etc.
Topical 1) Steroids (Triamcinolone
5-10mg)
2) Topical sensitizers
(Diphenycyprone, Squaric
acid dibutylester,
Dinitrochlorobenzene).
3) Anthralin cream 0.5-1%.
4) Minoxidil 2-5%.
5) Prostaglandin analogue.
Systemic 1) Steroids.
2) Phototherapy and
chemotherapy.
3) Cyclosporine 5 mg/kg,
MTX, Sulfasalazine.
4) JAK inhibitors.
Androgenic alopecia
Topical Minoxidil 5% 1ml twice
daily for men and once
daily for women.
Systemic 1) Finasteride 1mg.
2) Anti androgens
(Cyproterone acetate,
 spironolactone, flutamide)
in women.
Surgical Hair transplant.
Vitiligo
Topical 1) Cosmetic camouflage. Topical PUVA used in
2) Topical PUVA ( Psoralen cases with < 20% of total
0.05-0.1%). surface area
3) Steroids (0.1% depigmentation.
betamethasone)
Systemic 1) PUVA (Psoralen Systemic PUVA used in
0.5mg/kg). extensive vitiligo.
2) Steriods.
Surgical 1) Autologus mini grafting.
2) Epidermal grafting,
3) TransplantatIon of Non
cultured melanocytes.
4) Transplantation of
cultured melanocytes.
Impetigo
General Removal of crusts by soap
and water, potassium
permanganate 1/8000,
Gentian violet 1%.
Topical Antibiotics (Mupirocin, Mild and localized.
Fusidic acid, Neomycin,
Bacitracin).
Systemic Antibiotics (Flucloxacillin, Severe And
Erythromycin). lymphadenopathy.
Cellulitis and Erysipelas
Systemic Penicillin or Erythromycin
in pts allergic to penicillin.
HSV-1/2 (Herpes)
Topical 1) Acyclovir.
2) Gentian violet in oozing
lesions.
3) Antibiotic in 2ry
infections.
Systemic 1) Acyclovir 200 mg 5x for Systemic antivirals are
5-10 days. used in 1st attack and
2) Famcyclovir 125 mg 2x severe recurrent attack.
for 5 days.
Varicella (Chickenpox)
General 1) Bed rest.
2) Antihistamine,
antipyretic.
3) Antibiotics.
Severe cases Acyclovir or gamma
globulins
Herpes Zoster (Shingles)
Topical Analgesic, antibiotics if 2ry
infected, drying agent.
Systemic 1) Steroids in some cases.
2) Acyclovir 800 mg 5x for
5 days.
3) Famcyclovir 500 mg for
5 days.
4) Gabapentin for pain.
Warts (Human papilloma virus)
Local destructive Cryotherapy,
therapy Eletrotherapy, Surgical
excision, Trichloroacetic
acid.
Topical 1) Podophyllin.
2) Imiquimod 5%
(immunomodifier).
3)Diphenylcyclopropenone
(Immunotherapy).
4) Cidofovir.
Systemic 1) Cidofovir.
2) Retinoids.
3) Immunomodifiers.
Molluscum contagoisum
General 1) Curettage
electrocautery.
2) Needle transfixion.
3) Cryotherapy.
4) Chemical cautery (TCA).
Fungal skin infections
systemic 1) Griseofulvin 10-15
mg/kg.
2) Fluconazole (T.capitis
➔ 1.5-6 mg/kg –
Onychomycosis ➔ 150 mg
– Skin ➔ 100 mg)
 3) Itraconazole (T.capitis
➔ 3-5 mg/kg –
Oncychomycosis ➔ 200
mg – Skin ➔ 100-400 mg).
4) Terbinafine 250 mg.
Topical 1) Azoles.
2) Terbenafine.
3) Tolnaftate.
4) Amorolfine 5%.
5) Ciclopirox 8%.
Parasitic skin diseases
Topical 1) Benzyl Benzoate 10% Malathion 0.5 is specific
and 25%. for pediculosis.
2) Permethrin 5%.
3) Malathion 0.5%.
4) Sulphur 2-10% in
petroleum.
5) Crotamiton 10%
(Antipruritic).
6) Gamma benzene
Hexachloride 1%.
Systemic Ivermectin 200 µg/kg
Ichthyosis
General 1) Regular application of
moisturizers and peeling
creams (Salicylic acid).
2) Systemic retinoids
(acretin) in lamellar
ichthyosis.
Xeroderma pigmentosa
General 1) Complete protection
form UV exposure.
2) Systemic retinoids for
prevention of new
cancers.

Epidermolysis Bullosa
General Gene therapy, Avoid
trauma, wound dressing.
Urticaria
General Avoid triggers, Calamine
lotion and 1% menthol
suppress itching.
Systemic 1) Antihistamines:
•Cetirizine 5-10mg.
•Fexodenadine 180mg.
•Desloratidine 5mg.
•Loratidine 10mg.
•Hydroxyzine 10-50mg at
night.
•Diphenyhydramine 25-
50mg at night.
•Doxepin 10-50mg at
night.
•Cyproheptadine 4mg.
•Cimetidine 400mg.
2) Cyclosporine in severe
disease refractory to
antihistamines.
3) Prednisone in acute
urticaria.
4) Mast cell stabilizer.
5) Montelukast 10mg.
6) Omalizumab.
Syphilis
General 1) Penicillin (drug of Penicillin G 2.4 million
choice). unit for 1ry or 2ry stage,
2) Doxycycline. 7.2 million units for late
latent stage.
Gonorrhea
General 1) Ceftriaxone 250mg.
2) Cefexime 500mg.
3) Ciprofloxacin 500mg.
4) Spectinomycin 2gm.