ALBARKAT PHARMACEUTICAL INDUSTRIES.

STANDARD OPERATING PROCEDURE

SUBJECT / TITLE: HANDLING AND STORAGE OF COMPRESSED GAS CYLINDER

Page 1 of 2.
DOCUMENT ISSUE DATE REVIEW DATE SUPERCEDES DEPARTMENT

QA-SOP-005-00 JAN- 2023 JAN- 2026 NEW Q.A Department

1. PURPOSE

To provide the standard procedure for caring the gas cylinder.

2. SCOPE

The scope of this SOP to give the instruction for safety and proper handling of gas cylinder

3. RESPONSIBILITY

All Department Manager : To follow and implement this SOP.

Q.A. Manager : To ensure the implementation of this SOP.

4. PRECAUTION

4.1 All cylinders should be identified by their labels. Color coding may be helpful, but by itself is not reliable.
4.2 Cylinders of different types should be properly segregated in a shed to prevent exposure to direct sunlight.
4.3 Make sure the cylinders are firmly secured while store. If any of the cylinders has a label that is defaced and
unclear, it should be marked “CONTENTS UNKNOWN” and returned to manufacturer.

5. PROCEDURE:

A compressed gas is any material or mixture having in the container an absolute pressure greater than 40 psi
at 21°C or absolute pressure greater than 104 psi at 54°C. Compressed gases present several hazards: fire.
Toxicity, Corrosiveness and energy release due to pressure.

6. HANDLING:

6.1 All gas lines should be properly labeled with a color for identification.
6.2 Stand away from the face of the regulator while opening the valve.
6.3 Never check a gas cylinder to determine whether the cylinder is empty or full without using a pressure
gauge and regulators.
6.4 Always keep a wrench available to close the valve in case of emergency.
6.5 Do not use oil and greases on pressure regulators, gauges or other fittings.
6.6 To properly shut down a system supplies with a compressed gas, close high pressure valve, open the
needle valve to delivery side to bleed gas out of the regulator and turn the realtor valve counter clockwise
until it is loose.
6.7 A cylinder should never be emptied to a pressure to a pressure lower than 25 psi. Empty cylinders should be
clearly marked as “EMPTY” and returned, pending their dispatch to the manufacturer for refilling. Empty
and full cylinders should never be stored in the same place.

PREPARED BY: CHECKED BY: APPROVED BY:

Q.A OFFICER Asst. Manager Q.A Q.A MANAGER

 ALBARKAT PHARMACEUTICAL INDUSTRIES.
STANDARD OPERATING PROCEDURE
SUBJECT / TITLE: HANDLING AND STORAGE OF COMPRESSED GAS CYLINDER

Page 2 of 2.
DOCUMENT ISSUE DATE REVIEW DATE SUPERCEDES DEPARTMENT

QA-SOP-005-00 JAN- 2023 JAN- 2026 NEW Q.A Department

6.8 If a leak cannot be remedied by tighten a valve gland or packing nut, emergency action procedure should be
instituted. Leaking cylinders, in which the leakage cannot be stopped, are vented at a rate that will not cause
environmental and safety problems. The procedure should be carried out by personnel trained in safe
handling of compressed gas cylinders.

7. FREQUENCY OF REVISION

7.1 All documents are reviewed after every 4 years if there is no change.
7.2 In case of any permanent change is deemed to be necessary, the document can be revised at any time.

8. HISTORY

New

9. DISTRIBUTION

9.1 C.O.O
9.2 Q.A Manager.
9.3 All Department Managers.
9.4 Master File.

PREPARED BY: CHECKED BY: APPROVED BY:

Q.A OFFICER Asst. Manager Q.A Q.A MANAGER