PRENATAL DRUG (Nausea and Vomiting)

Drug Name Drug Indication Mechanism of Adverse Effect Contraindication Nursing Intervention or
Preparation Action Responsibilities
Generic Name: - Give Nausea and Unknown. The CNS: somnolence - Contraindicated in Before:
tablets vomiting of combination of women
doxylamine whole on an pregnancy in antihistamine hypersensitive to - Warn patient about adverse
succinate- empty women who and vitamin B6 drug, its components, reactions, including somnolence,
pyridoxine stomach don’t respond may cause and other increased falls, other CNS depressant
hydrochloride with a glass to anticholinergic ethanolamine- effects, dry mouth, dilated pupils,
of water. conservative effects, derivative dizziness, confusion, fats heartbeat,
Don’t crush, management decreasing antihistamines. and fluid retention.
Brand Name: split, or nausea. - Contraindicated
Bonjesta, allow with MAO inhibitors - Advised patient to avoid alcohol and
Dicletin, patient to - Use cautiously in sedating medications, including
Diclegis chew patients with asthma, antihistamine cough and cold
tablets. increased IOP, angle- products, opioids, and sleep aids,while
Available closure glaucoma, taking this drug because of increased
Form: stenosing peptic risk of additive effects.
10 mg/tab ulcer, or
(delayed- pyloroduodenal or - Caution patient to avoid driving and
release) urinary bladder neck operating heavy equipment or other
20 mg/tab obstruction because activities that require mental
(extended- of anticholinergic alertness.
release) effects.
- Teach patient to take drug as
prescribed an that drug isn’t to be
used on an as-needed basis.

During:

- Monitor patient for anticholinergic

effects such as dry mouth,
tachycardia, urine retention,
constipation, and ataxia
 - Monitor patient for somnolence,
increased falls, and other CNS
depressant effects.

After:

- Reassess for continued need for drug

as the pregnancy progresses.

POSTPARTUM DRUG ( Pain relief for uterine contraction)

Drug Name Drug Indication Mechanism of Adverse Effect Contraindication Nursing Intervention or
Preparation Action Responsibilities
Generic Name: PO Moderate to Unknown. CNS: agitation, - Contraindicated in Before:
Give with a severe pain Binds with incoordination, women
meperidine half glass of that requires opiod dizziness, hypersensitive to - Monitor respiratory and CV status
hydrochloride water an opioid receptors in dysphoria, drug, and in those carefully. Don’t give if respirations are
analgesic and the CNS euphoria, light- with significant below 12 bpm, if respiratory rate or
IV for which altering headedness, respiratory depth is decreased, or if change in
Brand Name: - Keep alternative perception of sedation, depression, acute or pupils is noted.
Demerol opioid treatments and emotional somnolence, severe bronchial
antagonist are response to seizures, asthma in an - When giving drug parenterally, make
Available (naloxone) inadequate. pain. hallucinations, unmonitored setting sure the patient is lying down
Form: available headache, or in the absence of
- Give drug paradoxical anxiety, resuscitative
Injection: 25 by direct physical equipment, and with During:
mg/mL, 50 injection dependence, known or suspected
mg/mL, 75 over 2 to 5 - Carefully monitor vital signs, pain
syncope, tremor, GI obstruction,
mg/mL, 100 minutes level, respiratory status, and sedation
confusion, dis- including paralytic
mg/mL Drug may level.
orientation. ileus.
also be
Solution: 50 - Monitor patient for signs and
given by CV: bradycardia, - Use cautiously in
mg/5mL symptoms of adrenal insufficiency
 slow cardiac arrest, older adults or such as nausea, vomiting, loss of
Tablet: 50 mg, continuous shock, hypotension, patients who are appetite, fatigue, weakness, dizziness,
100 mg infusion. tachycardia, debilitated and in and low BP.
- Drug is palpitations, those with increased
compatible flushing. ICP, head injury,
with the asthma, and other After:
most Gl: biliary tract respiratory
infusion spasms, conditions, - Reassess patient’s level of pain at
solutions constipation, dry supraventricular least 15 and 30 minutes after
including mouth, ileus, tachycardias, administration.
D5W, NSS, nausea, vomiting. seizures, abdominal
and LR. conditions, decreased
GU: urine bowel motility
retention. conditions, hepatic or
renal diseases,
Musculoskeletal: hypothyroidism,
muscle twitching, Addison disease,
weakness. urethral stricture, and
prostatic hyperplasia.
Respiratory:
respiratory arrest,
respiratory
depression.

Skin: diaphoresis,
pruritus, urticaria.

Other: induration,
local tissue
irritation, pain at
injection site,
phlebitis after IV
delivery,
hypersensitivity
reactions,
anaphylaxis.