> chapter 4. Second Wek of Development Baminar Germ Disc 49 (ominas fom preva pte) coe Perea) Figure 4.9 Tubal pregnancy. Embryo is approximately 2 months old and is about to escape through a rupture in the tubal wall fertilization of an oocyte lacking 2 nucleus followed by duplication ofthe male chromosomes t0 restore the diploid number These results also suggest that paternal genes regulate most ofthe development of the trophoblast because in moles this tissue differ entiates even in the absence of a female pronucleus. ‘Other examples of funcronal differences. in rater and paternal genes are provided by the ‘observation that certain genedc diseases depend on ‘whether the defective or missing gene is inherited from. the father or the mother For example,a microdeletion ‘on chromosome |S inherited from a father causes Embryo developing in reetoutorne pou Vagina Figure 4.10 Midiine section of badder uterus and rectum shows an abdominal pregnancy inthe rectouterine (Douglas) pouch. eR EE (continued on following word ee