Name:______________________________ Rating:________/20_____

Year and Sec.:________________________ Grade in model:___________/15

Date:_______________________________
Activity # __
Chromie Change
Objective:1. Illustrate the kinds of chromosomal mutations.
2. Differentiate the kinds of chromosomal mutations.
Materials:
Colored paper, pair of scissors, bond paper, glue/ paste
Procedure
A. Translocation
1. Using your colored paper, make models of two (2) chromosomes. One should have a different
color and size from the other.
2. Break the part of each of the chromosomes. Exchange the parts and attach them to each of the
other chromosomes.
3. Fill in the second column ( translocation) of the table.

B. Deletion
1. Make a model of a chromatid ( one of the duplicated copies of a chromosome).
2. When done, remove a portion of it ( close to either end of the chromosome or within the long
arm or short arm).If you choose to remove a part with the upper arms, make sure to join back
the bottom part.
3. Fill in the third column (deletion) table.

C. Inversion
1. Make a colored chromatid as shown in the illustration.
2. This time break a portion ( with 2 colors) of it. Refer to the illustration below.
3. Re-insert it to the chromatid in the reverse manner.
4. Fill in the fourth column (inversion) of the table.

Chromosomal Mutation Translocation Deletion Inversion

1.How many chromosomes are involved?( 1 pt

each)

2.How did you change the original structure of

the chromosome? ( 2 Pts each)

3.Which condition(s) do you think result(s) to

changes of chromosomal material? Pls. indicate
using loss, gain of genetic material ( 1 pt each)
Guide Questions:
1.How are the three chromosomal aberrations different from each other? How are they similar ?( 2 pts)
2. Do you think the normal genetic content of the chromosome is affected?( 1 pt)
3. Which condition results to gain of chromosome material? Loss of chromosomal material? ( 3 pts)
4. What are some possible effects of these chromosomal mutations? ( 2 pts)