Diagnosis of appendicitis is usually not especially diffi cult.

A considerable number of acute

abdominal emergency patients admitted to a hospital have appendicular infl ammation. So frequent
is this condition that it would almost appear that some do not trouble to attempt a differential
diagnosis. This is a serious mistake.

Because most of the deaths appeared to have occurred close to the water pump in Broad Street,
Snow took the view that this was the source of the problem. He examined the water and at first saw
nothing suspicious, but over a few days noted that the quality of the water varied, and that it
seemed to have small white flocculent particles floating in it. At this point, he decided to undertake a
systematic survey of the deaths in the vicinity. Eighty-three deaths, mapped according to place of
residence, had occurred within 3

Exposure to a foreign invader (antigen) activates the production of certain white blood cells in your
body called B cells (B lymphocytes). B cells produce plasma cells, which in turn produce a huge
number of antibodies designed specifically to fight that particular invader. These antibodies circulate
in your body’s fluids. The next time the antibodies encounter that invader in your body, they
recognize it and destroy it. And if needed, your body can rapidly resume production of an antibody it
has made before. In addition to the work of B cells, white blood cells called macrophages confront
and destroy foreign invaders. The macrophages “process” the invaders, figuring out if they present a
threat. If your body encounters a germ that it has never been exposed to before, information about
the germ is relayed to white blood cells called helper T cells. These cells aid in the development of
other infection-fighting cells, including memory T cell