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  • Tgs Biofar

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    hasfia H.R
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    This document contains data from a pharmacokinetic study measuring drug concentration (Cp) in the blood over time. It includes the time points measured, Cp values, calculated pharmacokinetic parameters, and area under the curve calculations. A one compartment model with first order elimination provided a good fit to the data, with an elimination rate constant (kel) of 0.195506 hr-1.

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    tgs biofar

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    This document contains data from a pharmacokinetic study measuring drug concentration (Cp) in the blood over time. It includes the time points measured, Cp values, calculated pharmacokinetic parameters, and area under the curve calculations. A one compartment model with first order elimination provided a good fit to the data, with an elimination rate constant (kel) of 0.195506 hr-1.

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    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
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    Download as xlsx, pdf, or txt
    8 views4 pages

    Tgs Biofar

    Uploaded by

    hasfia H.R
    This document contains data from a pharmacokinetic study measuring drug concentration (Cp) in the blood over time. It includes the time points measured, Cp values, calculated pharmacokinetic parameters, and area under the curve calculations. A one compartment model with first order elimination provided a good fit to the data, with an elimination rate constant (kel) of 0.195506 hr-1.

    Copyright:

    © All Rights Reserved
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    of 4

    waktu ( hr) Cp (mcg/ml) Ln Cp SLOPE kel r intersep LnCp' Cp'

    0 0 0 0 2.27151
    0.25 3.38 1.217876 -0.195506 0.195506 -0.999825 2.222633 9.231608
    0.5 5.62 1.726332 -0.195506 0.195506 -0.097753 0.906873
    0.75 7.5 2.014903 -0.195506 0.195506 -0.146629 0.863614
    1 7.88 2.014903 -0.195506 0.195506 -0.195506 0.822419
    1.5 8.44 2.132982 -0.195506 0.195506 -0.293259 0.745829
    3 6.75 1.909543 -0.195506 0.195506 -0.586518 0.556261
    6 3.38 1.217876 -0.195506 0.195506 -1.173035 0.309426
    12 0.94 -0.061875 -0.195506 0.195506 -2.34607 0.095745
    18 0.28 -1.272966 -0.195506 0.195506 -3.519105 0.029626
    24 0.09 -2.407946 -0.195506 0.195506 -4.69214 0.009167
    Cp'-Cp Ln Cp'-Cp slope kabs r

    5.851608 1.766717
    -4.713127 Err:502
    -6.636386 Err:502
    -7.057581 Err:502
    -7.694171 Err:502
    -6.193739 Err:502
    -3.070574 Err:502
    -0.844255 Err:502
    -0.250374 Err:502
    -0.080833 Err:502
    waktu ( hr)Cp (mcg/ml) Ln Cp SLOPE kel AUC]tn-1 t[AUC]0-tn k[AUC]0-tnCp + k[AUC[AUC]t'-~
    0 0 0 0 0 0 0.460344
    0.25 3.38 1.217876 -0.195506 0.195506 0.4225 0.4225 0.082601 3.462601 0.460344
    0.5 5.62 1.726332 -0.195506 0.195506 1.125 1.5475 0.302545 5.922545 0
    0.75 7.5 2.014903 -0.195506 0.195506 1.64 3.1875 0.623175 8.123175 0
    1 7.88 2.014903 -0.195506 0.195506 1.9225 5.11 0.999035 8.879035 0
    1.5 8.44 2.132982 -0.195506 0.195506 4.08 9.19 1.796699 10.2367 0
    3 6.75 1.909543 -0.195506 0.195506 11.3925 20.5825 4.023999 10.774 0
    6 3.38 1.217876 -0.195506 0.195506 15.195 35.7775 6.994711 10.37471 0
    12 0.94 -0.061875 -0.195506 0.195506 12.96 48.7375 9.528466 10.46847 0
    18 0.28 -1.272966 -0.195506 0.195506 3.66 52.3975 10.24402 10.52402 0
    24 0.09 -2.407946 -0.195506 0.195506 1.11 53.5075 10.46103 10.55103 0
    [AUC]0-~ k[AUC]0-~ Fabsorpsi FTA ln FTA Slope Ka r
    53.86784
    53.96784
    0
    0
    0
    0
    0
    0
    0
    0
    0

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