Professional Documents
Culture Documents
Oral Pathology Dent1411
Oral Pathology Dent1411
Oral Pathology Dent1411
Neoplasia
Description ofNeoplasia
Neoplasia new
growth, cells are uncontrolled
Neoplasm new growth of tissue, growth is uncontrolled and progressive
lumor swelling, used synonym for neoplasm
·
means as a
occurrence of Neoplasia
irreversible change in cells, passed onto new cells (uncontrollable cell multiplication)
->
abnormal process
causes of Neoplasia
->
chemicals:hundreds ->
Radiation: Sun, X-rays, nuclear fission
spontaneous from
->
->
Viruses:
oncogenic viruses (HPV) genetic mutation
Classification of Tumors
localized, encapsulated, cannot spread
·
-
Benign remains
Names of Tumors
Prefix is determined by tissue/cell of origin
·
Naming Malignant
Tumours
carcinoma: malignant, epithelium
·
Premalignant
·
lesions
-
LenkoPlakiaplague, biopsy may show epithelial dysplasia, squamous cell carcinomal
-
white
-Erythroplakia red smooth or granular or velvety), floor of mouth, tongue, soft palate
-
-Epithelial dysplasiapremalignant (to squamous cell carcinoma), may revent if stimulus removed
"slow
growing exophytic tumor; pebbly red and white surface
"numerous papillary epithelial projections filled w/ Keration
"epithelium differentiated, does not contain atypical cells, broad based rete
is well
pegs
-best of all SCC:no invasion through basement membrane
prognosis
=treatment surgical excision
->
skin tumor associated w/
malignant sun exposure
↳common face; (white adults)
on
nonhealing ulcer with rolled borders
streatment surgical excision, radiation; rarely metastasizes
Salivary Gland Tumors
"most often of junction of hard and soft palate
Pleomorphic adenoma Adenoid cystic carcinoma (cylindromal
·
·
carcinoma
Pleomorphic Adenoma Benign Mixed Tumor
· -
malignant
Benign Encapsulated Tumor
·
Monomorphic Adenoma
-
->
derived from tooth forming tissues;contain epithelium, mesenchyme, or combo
"usually benign, some rare malignantforms
Epithelial odontogenic tumors
·
Adenomatoid
Odontogenic tumor calcifying odontogenic cyst
·
Ameloblastoma
->
benign;islands/sheets
->
of polyhedral epithelial cells - adults, either sex
we calcifications win deposits treatment:
↳
Amyloid-like material Surgical excision
Rads:a unilocular/multioccular radiolucency- usually mand, bicuspid/molar area
~
Adenomatoid Odontogenic Tumor (AOT)
->
encapsulated, benign:70% in females (20,70% involve anterior jaw
~
more common in max, often associated with impacted teeth
↑rads:well-circumscribed radiolucency;may have
radiopaque areas
->
treatment:enucleation
mostcommon <40
*
microscopically)
->
Associated characteristic keratinization (round wl centres
wi
ghostcen clear
myxoma
·
·Central
-
cementifying and ossifying fibromas
Odontogenic Myxoma benign encapsulated, infiltrating
non tumor:Age 10-29
-Rads:multilocular, honeycombed radiolucency, poorly defined
margins
~mostoften in mand.;maybecome
large and displaced
~Treatment
surgical excision,
=
may recur
Cementifying/Ossifying Fibromas
->
Central -
->
not
-more common:
young children andadults, males, mand.bicnspid/molar
-rads:well or poorly defined unilmultiocular radiolucency
->
Treatment:surgical excision;low recurrance
Ameloblastic fibro-odontomae
·
benign
~features of ameloblastic fibroma and Odontoma
Complex:does
~
resemble
not teeth, posterior mandible
mostly adolescents and young adults clinical:failure of tooth to errupt
~ -
~
Treatment:Surgical excision
Tumours of SoftTissue
->
lipoma tumors of nervetissue vascular
->
tumors
Lipoma-benign tumor of mature fatcells
·
~Clinically: yellowish mass, thin epithelium layer common: buccal mucosa, vestibule. 7 4O
~micro: Well delineated, Uniform Sizelshape Treatment:surgical excision
-
Cavernous or
in no sex
Intraoral-most common tongue ill defined, pebbly surface ecystic in neck=cystic hygroma
-
on
Tx =
"Kapos; sarcoma - older men, Hive purple macules, plagues, exophytic tumors; hard palate and
gingiva
Tumors of Melanin producing cells