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    DR Gabriel Wallau Genomic Data Sharing Covid19 Brazil

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    iq_diana
    The document summarizes the successes and challenges of genomic data sharing during the COVID-19 pandemic in Brazil. The FIOCRUZ Genomic Network was able to share 76,477 genomes, representing 43% of Brazil's total genomic output. They trained over 270 researchers and established standard protocols for reliable data sharing. However, challenges remain around fully integrating data on virus genomes, disease severity, risk factors, and vaccine efficacy. Continued experiences sharing and addressing accountability and interoperability will help maximize public health impact going forward.

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    DR Gabriel Wallau Genomic Data Sharing Covid19 Brazil

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    iq_diana
    37 views18 pages
    The document summarizes the successes and challenges of genomic data sharing during the COVID-19 pandemic in Brazil. The FIOCRUZ Genomic Network was able to share 76,477 genomes, representing 43% of Brazil's total genomic output. They trained over 270 researchers and established standard protocols for reliable data sharing. However, challenges remain around fully integrating data on virus genomes, disease severity, risk factors, and vaccine efficacy. Continued experiences sharing and addressing accountability and interoperability will help maximize public health impact going forward.

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    Dr Gabriel Wallau genomic data sharing covid19 brazil

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    The document summarizes the successes and challenges of genomic data sharing during the COVID-19 pandemic in Brazil. The FIOCRUZ Genomic Network was able to share 76,477 genomes, representing 43% of Brazil's total genomic output. They trained over 270 researchers and established standard protocols for reliable data sharing. However, challenges remain around fully integrating data on virus genomes, disease severity, risk factors, and vaccine efficacy. Continued experiences sharing and addressing accountability and interoperability will help maximize public health impact going forward.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    37 views18 pages

    DR Gabriel Wallau Genomic Data Sharing Covid19 Brazil

    Uploaded by

    iq_diana
    The document summarizes the successes and challenges of genomic data sharing during the COVID-19 pandemic in Brazil. The FIOCRUZ Genomic Network was able to share 76,477 genomes, representing 43% of Brazil's total genomic output. They trained over 270 researchers and established standard protocols for reliable data sharing. However, challenges remain around fully integrating data on virus genomes, disease severity, risk factors, and vaccine efficacy. Continued experiences sharing and addressing accountability and interoperability will help maximize public health impact going forward.

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    of 18

    SUCCESSES AND CHALLENGES

    OF GENOMIC DATA SHARING

    DURING THE COVID-19

    PANDEMICS IN BRAZIL

    Gabriel da Luz Wallau


    Public Health Researcher
    Oswaldo Cruz Foundation - Brazil

    TOPICS

    History of the network;

    Achievements;

    Challenges;

    Lessons learned;

    What is next: preparedness to maximize impact on public health.


    BACK IN 2020
    Scattered
    FIOCRUZ GENOMIC NETWORK
    BUILDING TRUST - DATA SHARING
    Two ways knowledge transfer
    GOLD STANDART PROTOCOLS -> DATA SHARING
    Wet and Dry Lab

    Accountability and

    data protection
    FIOCRUZ GENOMIC NETWORK OUTPUTS

    76.477 genomes
    (43% of the national output)
    Representativeness

    905 technical

    reports

    Best practices

    Source: https://www.genomahcov.fiocruz.br/
    FIOCRUZ GENOMIC NETWORK OUTPUTS
    Virological

    Inference protocols

    Rapid test evaluation


    DATA SHARING - OVERALL POPULATION

    Source: https://www.genomahcov.fiocruz.br/
    TRAINING WET AND DRY LAB

    Training more than 270 researchers from BR (25 Brazilian states) + LA;

    Routine analysis: RS; BA; PB; AL; ES; MS; GO; SE; RJ; SP; MG; BA; CE; PI;

    International groups: Guatemala, USA-Michigan, Peru;

    Other viruses: Dengue, Zika, Chikungunya, Measles and Monkeypox.


    DATA SHARING - RELIABILITY AND REPRODUCIBILITY


    ViralFlow
    GenBank ID Submission

    Pathogen reads
    only

    Core analysis
    Agnostic modules

    ViralFlow Virus-specific
    analysis
    NAGOYA PROTOCOL

    Regulatory marks
    in Brazil

    Submission

    Exemption durying Pathogen reads


    pandemic emergency only

    All labs from the network


    registered to access
    human heritage.
    CHALLENGES AHEAD
    CHALLENGES
    Data integration

    Disease severity

    Risk factors

    Vaccine efficacy
    CHALLENGES
    Data integration - VirusGenomeDB

    Risk factors Disease severity


    Vaccine efficacy
    LEVERAGING EXPERIENCES

    Experiences exchange and local context are key;

    Data sharing - considering different needs and accountability;

    Data integration and interoperability is crutial to maximize impact.


    Acknowledgment

    Thank you

    Obrigado

    Gabriel da Luz Wallau - gabriel.wallau@fiocruz.br

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