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Integrating Gross Anatomy Into A Clinical Oncology.8
Integrating Gross Anatomy Into A Clinical Oncology.8
Integrating Gross Anatomy Into A Clinical Oncology.8
Abstract
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The amount of time devoted to teaching direct visualization and palpation of human Anonymous surveys were distributed to
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gross anatomy to medical students is cadavers, thus enabling the understanding course participants to assess the three
declining. This topic remains critically of complex three-dimensional and anatomic components of the course. Survey results
important for some medical students, principles. The audience for this course indicate that the participants found the
especially those seeking training in consists of medical students rotating anatomy lectures, clinical case
anatomy-laden specialties. The authors through and the residents and clinical presentations, and dissection presentations
describe a course currently offered in the faculty in the department of radiation all to be interesting, relevant, and of high
department of radiation oncology in the oncology. Anatomists and radiation quality. This course is therefore favored by
Duke University School of Medicine, oncology residents together present students, residents, and faculty as a way to
developed in 2005, that expands anatomy monthly didactic lectures, clinical case
supplement gross anatomy education
education into the medical school clinical presentations, and cadaver-based
during training for a specialty in which
years.The aim of the course is to help demonstrations about the relationships
anatomy knowledge is essential.
reinforce anatomy knowledge in the between a tumor’s anatomic location
clinical context of radiation oncology and its symptoms, patterns of spread, Acad Med. 2007; 82:469–474.
priorities and concerns, as well as to provide and treatment considerations.
A gross anatomy course and cadaveric need at least a refresher course in gross decide which regions of the body are to
dissection are long-standing traditions anatomy.4 be treated with radiation therapy (RT)
in medical education. Students learn and to design RT fields to optimally
anatomy while confronting death; they Concern about adequate anatomy irradiate target tissues. They must
also learn how to work cooperatively preparation is most pronounced in simultaneously understand the
within their peer group.1–3 The hours specialties that rely more heavily on relationship between the target tissues
allotted to gross anatomy during the anatomic knowledge.4 Given that the and surrounding normal structures for
basic sciences years of medical school trend of decreasing hours dedicated to two reasons: to design treatment beams
have decreased steadily over the past anatomy in the basic science years shows that minimize the radiation dose to
century.2,4,5 Because of this trend and no signs of reversing, one way by which critical normal structures near the tumor,
the sheer quantity of information that some medical schools have addressed this and to understand how the surrounding
students must attempt to learn in gross dilemma is by supplementing medical anatomy dictates the patterns of cancer
anatomy, up to 71% of residency students’ anatomy education during their spread so that RT can be delivered to the
directors report that incoming residents clinical years. This approach allows those likely areas of tumor extension. Routine
students with interest in anatomy-laden clinical practice relies heavily on
fields to reinforce their knowledge in the diagnostic imaging such as computed
context of focused, clinically relevant tomography (CT), magnetic resonance
Dr. Zumwalt is a research associate with joint scenarios. In this article, we present and imaging (MRI), and positron emission
appointments in the Department of Biological
Anthropology and Anatomy and in Gross Anatomy
evaluate a model for one such approach tomography (PET). Students and
and Anatomical Gifts, Duke University School of that has been adopted at the Duke residents must typically relearn gross
Medicine, Durham, North Carolina. University School of Medicine, in which anatomy in the context of these medical
Dr. Marks is professor and residency program anatomists and members of a clinical images to correlate the three-dimensional
director, Department of Radiation Oncology, Duke department, radiation oncology, (3D) anatomy they learned in the gross
University School of Medicine, Durham, North collaboratively direct and teach an anatomy class with the anatomy
Carolina.
anatomy course to students and other observable on these two-dimensional
At the time this article was written, Dr. Halperin individuals in that department. (2D) images.
was professor of radiation oncology, vice dean, and
associate vice chancellor for academic affairs, Duke
University School of Medicine, Durham, North In July 2005, we developed a course
Carolina.
Background and Context entitled Oncoanatomy and integrated it
Correspondence should be addressed to Dr. Radiation oncology is one nonsurgical into the curriculum for medical students
Zumwalt, Box 3170, Department of Biological specialty in which knowledge of gross and residents in the department of
Anthropology and Anatomy, Duke University anatomy and of the patterns of spread of radiation oncology at the Duke
Medical Center, Durham, NC 27710; telephone:
(919) 668-6417; fax: (919) 684-8034; e-mail: malignancies is critically important.6 – 8 University School of Medicine. The
(azumwalt@duke.edu). Radiation oncologists typically need to motivations for developing this course
were twofold. First, as described above, anatomic information was routinely structures demonstrates common
radiation oncologists must understand incorporated into clinical evaluations and patterns of cancer spread and the
the complex anatomy of many body decisions. rationale for subsequent treatment
regions. The detail and scope of planning. Some examples are shown in
information that students usually retain A faculty member and the chief resident List 1.
after their initial gross anatomy class is in radiation oncology then met with the
usually inadequate for this purpose.4 This anatomists to formulate an educational
program for incorporating anatomy into Course logistics and content
course was developed to help reinforce
anatomy knowledge in the clinical the radiation oncology curriculum. The audience to whom this course is
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context of radiation oncology priorities Together, they identified common directed is the population of medical
and concerns. Second, direct clinical scenarios wherein gross anatomy students rotating through the department
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visualization and palpation of human instruction would enhance the students’ of radiation oncology, who are required
cadavers provides a unique means for understanding of the disease process and to attend any oncoanatomy session that
understanding complex 3D and anatomic the implications for RT field design. meets during their rotation. Because
principles, and we believe that this These clinical scenarios were ones in radiation oncology is an optional clinical
approach is superior to computer- which understanding the 3D relationship rotation for medical students at Duke,
assisted imaging-based tools. However, between the tumor and adjacent normal the number of students in any given
because clinical work relies on image-
based tools,3 oncologists must be able to
translate the 2D images they see in CT, List 1
MRI, and PET scans into the reality of Examples of Clinical Scenarios with Anatomic Correlates for Oncoanatomy
complex 3D anatomy. We hope that by Sessions
improving their comprehension of 3D 1. Cancer in the pancreas/biliary tract: Discuss a patient presenting with painless jaundice.
anatomic relationships, the course will Evaluation leads to the diagnosis of cancer of the head of the pancreas, or a tumor in the
help the participants more proficiently common bile duct
assess 2D diagnostic images. Gross anatomy correlates:
● Anatomy of the biliary tree and its proximity to the pancreas
Development of the ● Proximity of the pancreas to the kidney and liver and implications for radiation
Oncoanatomy Course techniques
This course was collaboratively developed ● Proximity of pancreas to celiac plexus and spinal cord and implications for presentation
by members of the department of of pain
radiation oncology and the department ● Nodal drainage to the celiac vessels and implications for resectability
of biological anthropology and anatomy.
● Whipple operation and other pancreas resection approaches
To familiarize themselves with the issues
and objectives of radiation oncology, the 2. Tumor obstruction of superior vena cava: Discuss a patient whose presenting
anatomists, who are basic science faculty, complaint is shortness of breath and who is found to have dilated neck and arm veins.
Subsequent evaluation reveals small cell cancer and a mediastinal mass
first attended several of the radiation
oncology department’s “traditional” case Gross anatomy correlates:
conferences. These 30- to 60-minute ● Proximity of superior vena cava to other intrathoracic structures, in particular the node-
conferences are prepared by a resident bearing areas of the mediastinum
or medical student with guidance from ● Collateral circulation occurs through the azygous system, which enters the superior vena
senior residents or faculty. The student cava
uses slides and illustrations from
● Demonstrate that collateral circulation may vary depending on whether the azygous
operative specimens or intraoperative system is patent. If the superior vena cava obstruction is inferior to the azygous insertion,
procedures to present a particular the collateral flow will extend to the lower body
question or issue about the management
● Review the location of the veins versus arteries in the chest, including where central lines
of a patient he or she has seen. The are placed
literature pertinent to this question is
presented and discussed in an interactive 3. Cancer of the prostate: Patient presents with urinary hesitancy and frequency. Exam
reveals an enlarged prostate; biopsy of a palpable nodule is positive for cancer. Discuss
manner in which the medical staff asks therapeutic options and how the toxicities of each relate to the local anatomy
the students and residents questions.
Members of the radiation oncology Gross anatomy correlates:
clinical faculty also provided several ● Proximity of prostate to bladder; hence, risk of bladder injury from radiation therapy,
educational sessions for the anatomists, particularly with interstitial catheters
addressing basic principles of oncology ● Proximity of prostate to rectum; hence, risk of rectal toxicity from external-beam
(e.g., cancer biology, tumor staging, radiation therapy
treatment approaches) and the anatomic
● Proximity of small intestine relative to pelvic nodes, and the impact of elective nodal
underpinnings of radiation oncology. irradiation on small bowel
One of the anatomists shadowed a
radiation oncologist in the clinic for ● Review the surgical approaches to the prostate and associated normal tissues of concern
for each
about 12 hours to observe firsthand how
rotation is small (usually two to four knowledge using textbooks and online versus the retroperitoneal location of
students), but most of these students resources to become more familiar with the the second and third parts of the
are particularly interested in radiation disease process. Total preparation time is duodenum.
oncology as a potential specialty. approximately 5 to 20 hours for each 2. The stomach, duodenum, pancreas,
Several students have attended many individual, with the variation resulting and liver were demonstrated along
oncoanatomy sessions as they were from differences in the level of familiarity with the porta hepatis and the major
involved in longer-term activities in the and complexity of the topics and variation vessels of the area. This dissection
radiation oncology department, such as in the extent to which detailed cadaver demonstrated the close proximity of
longitudinal clinics or research projects. dissection is required for a particular the pancreas to the duodenum, porta
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The residents in the department are demonstration. hepatic, and liver, illustrating the ease
strongly encouraged to attend, and the
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The format for each oncoanatomy with which pancreatic cancer may
entire clinical faculty is also invited. spread to nearby organs.
The only requirement for completion of session is as follows:
the course is attendance (e.g., there are 1. A 10- to 15-minute presentation by 3. The GI tract and its associated vessels
no textbooks or tests). the anatomist on the anatomic region were removed and were demonstrated
in question and the relevant from the posterior view to illustrate
The course meets monthly in a one-hour- embryology and comparative anatomy the proximity of these vessels to the
long time slot that is dedicated to the using anatomic and medical pancreas and other organs. These
traditional case conference during other illustrations. relationships are important because
weeks. Because there are few conflicts the spread of pancreatic cancer to the
2. A 10- to 15-minute case presentation surrounding soft tissues and
with patient responsibilities at this time, by a radiation oncology resident.
attendance is typically high, with 100% of lymphatics often can explain the
These presentations include a review patient’s symptoms and determines
the two to four medical students, 80% to of the patient’s history and diagnostic
100% of the seven to nine residents, and the resectability of the cancer.
imaging, a description of the tumor
several of the clinical faculty in the staging, and a discussion of common Access to cadavers
department attending. Faculty attendance symptoms at presentation and how
to any given session is dictated primarily The oncoanatomy course uses the
they relate to the gross anatomy.
by the topic being covered that day, but cadavers that the first-year medical
3. Thirty to 40 minutes of instruction students have previously dissected,
approximately 70% of the clinical faculty
using specially prepared cadaveric thereby making further use of these
in the department of radiation oncology
specimens. valuable resources. We use these bodies
have attended at least one session.
during the months in which the gross
Both 10- to 15-minute presentations are
The topic for any given session is cancer anatomy class is ongoing and for a
informal didactic lectures that occur in a
of a particular location in the body. Each number of months after the course ends.
small conference room adjacent to
topic is selected on the basis of the Eventually, the cadavers are dissected
the gross anatomy lab. After the
available cadaveric material and beyond the point of being useful. In
presentations, the group moves into the
prevailing interests in the department addition to the gross anatomy cadavers,
anatomy lab, where the class divides into
at that time. For example, once the three extra cadavers per year are set aside
two groups of 5 to 10 individuals per
first-year gross anatomy students had from Duke’s anatomical gifts program for
group, depending on class attendance
completed their dissections of the head, use in the oncoanatomy course as well as
that day. The anatomists present two to
we were able to use the same cadavers to in several other advanced anatomy
four cadaver dissections to each of these
study the presentation and spread of courses.
groups. These dissections are more
cancer of the nasopharynx. Similarly, focused and extensive than is typical for a
when a particularly interesting case Course assessment
gross anatomy class, to illustrate the
involving a parotid gland tumor was anatomy relevant to the disease and its We distributed a confidential survey to
being treated by physicians in the patterns of spread. Each presentation 18 individuals, all of whom had attended
department, we took the opportunity to lasts 10 to 15 minutes, after which the the conferences in the first six months
explore the anatomic considerations groups rotate to the next demonstration. they were offered (July to December
relevant to this treatment. For example, in the session addressing 2005); our research was exempt from IRB
adenocarcinoma of the pancreas, three approval. All individuals (seven medical
In each session, one radiation oncology separate dissections were presented. One students, seven residents, and four
resident and one anatomist prepare anatomist presented dissection number faculty) responded to the survey.
lectures, and two or three other anatomists one, and a second anatomist presented Respondents may have attended up to six
prepare dissection demonstrations. In dissections two and three. sessions. At the time when the surveys
preparation for each presentation, the were distributed, sessions had covered
resident discusses with the anatomists the 1. The stomach and bowel were removed cancers of the nasopharynx, pancreas,
clinical and anatomic factors that are to provide an anterior view of the cervix, gastroesophageal region, and the
pertinent to understanding the behavior pancreas in situ. The proximity of the superior sulcus of the lung (Pancoast
and treatment of the disease. These duodenum to the pancreas was readily tumor). Because of the medical students’
discussions normally occur about two apparent in this view, as was the rotation schedules, most of the students
weeks before the scheduled class session. intraperitoneal location of the first had only attended one of the six sessions
The anatomists then supplement their and fourth parts of the duodenum that had occurred at the time the survey
was distributed. Most residents had attended? (case study, anatomy lecture, three parts of the course for all sessions as
attended all of the sessions, and the dissection) well as in the overall impressions of the
faculty had attended between one and respondents (Table 1). The faculty
four sessions. ▪ On a scale of 1 to 10 (1 ⫽ useless, 10 ⫽ ranked the relevance of the class to their
very useful), how would you rate the work somewhat lower than did the
The survey sought to assess the course relevance to your work of the topic(s) medical students and residents (faculty:
both qualitatively and quantitatively. The discussed in the oncoanatomy sessions 8.6 out of 10; students and residents: 9.8
first two questions on the survey listed below? out of 10).
identified the respondent’s rank (medical
▪ Please tell us about anything that you
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Table 1
Participants’ Satisfaction, by Session Topic (Tumor Site), with Oncoanatomy
Course, Department of Radiation Oncology, Duke University School of Medicine,
January 2006*
Superior
sulcus Gastro-
Participants’ rating of: Nasopharynx (Pancoast) esophageal Pancreas Cervix Overall†
Interest in the session
...................................................................................................................................................................................................................................................................................................................
Clinical case study 8.3 9.2 9.6 9.0 9.6 9.5
...................................................................................................................................................................................................................................................................................................................
Anatomy lecture 9.3 9.3 9.9 9.2 9.7 9.8
...................................................................................................................................................................................................................................................................................................................
Dissection presentation 9.8 9.7 10.0 9.3 9.8 10
Quality of the session
...................................................................................................................................................................................................................................................................................................................
Clinical case study 8.4 9.2 9.6 9.0 9.6 9.5
...................................................................................................................................................................................................................................................................................................................
Anatomy lecture 8.5 9.3 9.8 9.2 9.8 9.8
...................................................................................................................................................................................................................................................................................................................
Dissection presentation 9.8 9.7 10.0 9.3 9.8 10
Amount of new knowledge covered
by the session
...................................................................................................................................................................................................................................................................................................................
Clinical case study 8.3 7.8 8.4 6.9 7.8 8.6
...................................................................................................................................................................................................................................................................................................................
Anatomy lecture 8.0 7.7 8.7 7.2 7.9 9.3
...................................................................................................................................................................................................................................................................................................................
Dissection presentation 9.3 8.2 8.8 7.6 8.1 9.6
Relevance of the topic to their work 9.2 9.5 10.0 9.0 9.1 NA
* Each session was rated individually (on a scale of 1 to 10, where 1 ⫽ low, 10 ⫽ high) by those attending that
session. Data shown are the average results from seven medical students (second- to fourth year), seven
residents/fellows, and four faculty members, and are organized according to the sessions assessed.
†
Overall refers to the individual’s opinion of that aspect of the course overall.
creative dissections that demonstrate in other departments in which anatomic and radiologic imaging in teaching anatomy.
clinical concepts in ways that the knowledge is important, such as surgery Acad Med. 2005;80:745–749.
radiation oncology staff would not have (of all types), radiology, gastroenterology, 4 Cottam WW. Adequacy of medical school
considered. and obstetrics– gynecology. gross anatomy education as perceived by
certain postgraduate residency programs and
anatomy course directors. Clin Anat. 1999;12:
Conclusions Acknowledgments 55–65.
5 Patel KM, Moxham BJ. Attitudes of
The oncoanatomy course has been a This study was funded by the Duke University professional anatomists to curricular change.
success. Attendees find it interesting and School of Medicine.
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