Scribd Logo
Upload

Welcome to Scribd!

  • 8 views

    Non-Modifiable Factors Modifiable Factors: (Causative Agent: Respiratory Syncytia Virus)

    Uploaded by

    Venice Joy Celocia
    RSV pneumonia is caused by the respiratory syncytial virus entering the nasal and conjunctival mucosa and binding to epithelial cells in the nasopharynx. It can then spread to the lower respiratory tract. Key modifiable risk factors include close contact with infected individuals and poor hand hygiene. Symptoms typically appear within 2-8 days and include fever, cough, and rhinitis. Without treatment, the virus can cause respiratory failure, heart failure, liver failure, and long-term wheezing.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content

    You might also like

    Non-Modifiable Factors Modifiable Factors: (Causative Agent: Respiratory Syncytia Virus)

    Uploaded by

    Venice Joy Celocia
    8 views3 pages
    RSV pneumonia is caused by the respiratory syncytial virus entering the nasal and conjunctival mucosa and binding to epithelial cells in the nasopharynx. It can then spread to the lower respiratory tract. Key modifiable risk factors include close contact with infected individuals and poor hand hygiene. Symptoms typically appear within 2-8 days and include fever, cough, and rhinitis. Without treatment, the virus can cause respiratory failure, heart failure, liver failure, and long-term wheezing.

    Original Description:

    Original Title

    Untitled

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    RSV pneumonia is caused by the respiratory syncytial virus entering the nasal and conjunctival mucosa and binding to epithelial cells in the nasopharynx. It can then spread to the lower respiratory tract. Key modifiable risk factors include close contact with infected individuals and poor hand hygiene. Symptoms typically appear within 2-8 days and include fever, cough, and rhinitis. Without treatment, the virus can cause respiratory failure, heart failure, liver failure, and long-term wheezing.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    8 views3 pages

    Non-Modifiable Factors Modifiable Factors: (Causative Agent: Respiratory Syncytia Virus)

    Uploaded by

    Venice Joy Celocia
    RSV pneumonia is caused by the respiratory syncytial virus entering the nasal and conjunctival mucosa and binding to epithelial cells in the nasopharynx. It can then spread to the lower respiratory tract. Key modifiable risk factors include close contact with infected individuals and poor hand hygiene. Symptoms typically appear within 2-8 days and include fever, cough, and rhinitis. Without treatment, the virus can cause respiratory failure, heart failure, liver failure, and long-term wheezing.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 3

    NON-MODIFIABLE FACTORS

    • Age – may affect all ages but commonly


    causes problems among infants (>12 MODIFIABLE FACTORS

    months) • Close contact with people having

    • Sex – Male/Female infected saliva or nasal secretions

    • Underlying disease: congenital heart disease • Poor hand hygiene

    RSV PNEUMONIA
    (Causative agent: respiratory syncytia
    DIRECT INDIRECT
    virus)
    • Direct contact (kissing) • Fomites

    • Large droplets (cough/sneeze)


    RSV enters nasal/ conjunctival mucosa and binds to
    apical ciliated epithelial cells of nasopharynx

    Release & invasion of RSV Uncoating of capsid, viral RSV-F protein fuses with
    virions to neighboring cells replication, transcription, cell membrane of the host RSV-G protein
    creating multinucleated translation, maturation, & and release its binds to host cell
    syncytia assembly nucleocapsid to the surface
    cytoplasm
    Fever, cough, and
    Cellular destruction of WBC infiltrates the site Mucus builds up in rhinitis (early
    infected cells attracts releasing chemotoxic nasopharynx and symptoms show
    nearby immune cells cytokines & histamine w/c inflammation of within 2-8 days)
    (NK cells) activates inflammatory nasal tissue after exposure
    response
    RSV migrates of URT to lower respiratory tract (LRT) via intercellular
    transmission through the lower airways (Piedimonte and Perez, 2014)

    Virus propagates and enters respiratory


    epithelium of LRT

    Rhonchi,
    Host inflammatory Activation of humoral & Inflammation & swelling due to Inspiratory and
    response is triggered cytotoxic T-cell which fluid & mucus build up expiratory
    attach to infection site narrowing the airway of wheezing
    bronchi towards bronchioles

    Formation of mucus plugs (fluid,


    Air trapping in
    dead cells) which fall to the alveoli Lung infiltrates →
    alveoli
    (air sacs) Hyperexpansion of
    lungs

    Decrease in CO2 buildup because of


    concentration of oxygen mucus plugs in airways

    Relative Respiratory
    Hypoxemia Acidosis
    z

    Relative
    Respiratory
    Hypoxemia
    Acidosis

    Subcostal If not attended/ treated


    Difficulty /Painful
    Retraction, Nasal immediately, can lead to:
    Breathing due to
    Flaring
    mucus plugs in
    lungs Respiratory failure

    Heart failure

    Liver failure
    Tachycardia Tachypnea
    Irritable/ Easily
    Long-term wheezing &
    agitated
    asthma (Bates, 2020)
    requires energy
    Re-infection with RSV
    and secondary
    infections
    Lethargy

    You might also like