Professional Documents
Culture Documents
Krok 1 Pharmacy 2008
Krok 1 Pharmacy 2008
on has tetraquetrous stalk, flowers with disperse systems are widely applied in
bilabiate corolla, coenobium fruit. These pharmaceutical practice. What method
characteristics are typical for the followi- of sol production relates to physical
ng family: condensation?
A. Lamiaceae A. Solvent substitution
B. Papaveraceae B. Reduction
C. Polygonaceae C. Oxidation
D. Solanaceae D. Hydrolysis
E. Scrophulariaceae E. Double exchange
13. Name a complex compound that has 19. A child with evident hypotrophy got
antitumoral activity: edemata on his lower extremities, asci-
tes. What is the main mechanism of
A. [P t(NH3 )2 Cl2 ] pathogenesis of cachectic edema?
B. [Co(NH3 )5 NO3 ]Cl2
C. Na4 [Sn(OH)3Cl3 ] A. Drop of oncotic pressure of blood
D. [Cu(NH3 )4 (SCN)2 ] plasma
E. K2 Na[Co(NO2 )6 ] B. Rise of hydrostatic blood pressure
C. Rise of oncotic pressure of intercellular
14. Solution applied as isotonic soluti- fluid
on should have the following osmotic D. Increased permeability of vascular wall
pressure: E. Disturbance of lymph outflow
A. 700 - 800 kPa 20. A patient has impaired mesopic vision,
B. 200 - 300 kPa his photopic vision is normal. What is the
C. 300 - 400 kPa probable cause of such vision anomaly?
D. 500 - 600 kPa
E. 900 - 1000 kPa A. Vitamin A deficiency
B. Hyperopia
15. According to Schultze-Hardy rule C. Cones disfunction
coagulating action of coagulant ion is D. Myopia
affected by: E. Vitamin D deficiency
A. Ion charge 21. Thiocyanatometry is based upon using
B. Ion size of secondary standard solution of potassi-
C. Adsorbability um thiocyanate that should be standardi-
D. Hydratability zed according to the following standard
E. Polarizability solution of:
16. What reaction is applied for detection A. Silver nitrate
of F e3+ cation? B. Hydrochloric acid
C. Sulfuric acid
A. Complexing D. Iron (II) sulfate
B. Precipitation E. Copper (II) nitrate
C. Hydrolysis
D. Neutralization 22. Concentration of potassium di-
E. Reduction chromate in a solution was determined
by means of iodometry. Name a titrant of
17. Dimethyl glyoxime entered into reacti- iodometric method for determination of
on with a solution that contained cati- strong oxidizer:
ons of the IV analytical group (acid-base
classification). The deposition turned cri- A. Sodium thiosulfate
mson. What cation caused this analytical B. Sodium hydroxide
effect? C. Potassium iodide
D. Potassium permanganate
A. Nickel cation (II) E. Potassium bromate
B. Mercury cation (II)
C. Copper cation (II) 23. Solution of potassium chromate was
D. Cadmium cation (II) added to a solution under examination.
E. Cobalt cation (II) As a result of it some yellow deposition
settled down. This deposition cannot be
18. Drugs in form of colloid- dissolved in acetic acid. This means that
Krok 1 Pharmacy 2008 3
45. During sanitary and bacteriological limbs is increased, their spinal reflexes
examination of air in a drugstore it was are intensified, reflex zones are increased.
revealed that the air had high concentrati- What type of CNS disorder is it?
on of sanitary meaningful microorgani-
sms. What microorganisms are these? A. Central paralysis
B. Peripheral paralysis
A. Staphylococcus aureus and hemolytic C. Spinal shock
streptococcus D. Atonic paralysis
B. Diphtheritic and tuberculous bacilli E. Reflex paralysis
C. Colibacilli and blue pus bacilli
D. Epidermal staphylococcus and Sarcina 51. Bacteriological control of unsterile
E. Enterococci and Citrobacter drugs allows presence of small quantity of
some microorganism groups. What group
46. Steroid hormones are synthesi- is meant?
zed out of a precursor that contai-
ns cyclopentanoperhydrophenanthrene. A. Sarcina
Name this precursor: B. Colon bacillus
C. Bacillus pynocyaneus
A. Cholesterol D. Staphylococcus aureus
B. Acetyl-CoA E. Hemolytic streptococcus
C. Malonyl-CoA
D. Levulinic acid 52. As a result of reduced water
E. Tyrosine reabsorption in nephron tubules daily di-
uresis of a patient has increased up to 10
47. In the pharmaceutical production litres. This might be caused by reduced
processes of drug synthesis take place secretion of the following hormone:
under different conditions. Entropy stays
unchanged in the following process: A. Vasopressin
B. Aldosterone
A. Adiabatic C. Parathormone
B. Isothermal D. Thyrocalcitonin
C. Isochoric E. Insulin
D. Isobaric
E. Polytropic 53. A product of complete acetylation of
glycerine relates to the following class of
48. Pulp of a needle leaf consists of living organic compounds:
tissue with inner ansiform protuberances
of membrane and chloroplasts along A. Ester
them. What is type of this leaf’s B. Ether
parenchyma? C. Ketone
D. Acetal
A. Plicate E. Phenol
B. Spongioid
C. Palisade 54. Name a product of ester condensation
D. Storage of acetaldehyde (Tishchenko reaction):
E. Aeriferous
49. A patient suffering from gastric ulcer
for a long time has dramatic emaciation,
skin pallor, appetite loss, aversion to meat
products. Biopsy of mucous membrane
of stomach revealed cellular atypia. What A. Ethyl acetate
pathology are these symptoms typical for? B. Acetone
C. Crotonic aldehyde
A. Malignant tumour of stomach D. Malonic acid
B. Benign tumour of stomach E. Acetoacetic aldehyde
C. Polyposis
D. Hypertrophic gastritis 55. Water-soluble vitamins take coenzyme
E. Helminthic invasion form in an organism. Thiamine di-
phosphate is coenzyme of the following
50. A patient had cerebral haemorrhage vitamin:
that made impossible active motions of
left arm and leg. Muscle tone of these
Krok 1 Pharmacy 2008 6
75. A few minutes afer repeated cardiac insufficiency has got soft ti-
introduction of penicillin a patient got ssue edemata on his shins. What is the
dyspnea, tongue numbness, hyperemia leading pathogenetic factor of edema
and then skin pallor. The patient also lost development?
consciousness. What is the cause of such a
grave condition? A. Rise of hydrostatic pressure in capillari-
es
A. Anaphylactic shock B. Drop of osmotic pressure in blood
B. Serum sickness plasma
C. Hemolytic anemia C. Rise of oncotic pressure in tissues
D. Acute glomerulonephritis D. Drop of hydrostatic pressure in capi-
E. Bronchial asthma llaries
E. Rise of osmotic pressure in tissues
76. Cations of the third analytical group
(acid-base classification) can be isolated 81. It is known that depending on pH
in course of systematic analysis by means of cellular fluid petal coloration can vary
of the following group reagent: from blue-and-violet to pink and light pi-
nk. This is caused by presence of:
A. 1 M solution of sulfate acid in presence
of ethanol A. Anthocyanins
B. 1 M solution of potassium chromate B. Carotins
C. 0,1 M solution of sodium carbonate C. Xanthophylls
D. 0,1 M solution of ammonium oxalate D. Phycobilins
E. 1 M solution of ammonium carbonate E. Chlorophylls
77. Solution of potassium iodide was 82. Which of the following plants has
added to the solution acidated with sulfate pome fruit?
acid that contained anions of the third
analytical group. Release of free iodine A. Sorbus aucuparia
is observed. What anion are present in the B. Prunus domestica L.
solution? C. Amygdalus communis
D. Rosa majalis
A. Nitrite ion E. Prunus padus
B. Carbonate ion
C. Sulfate ion 83. Bacteriological examination for
D. Bromide ions bacteria carrying of drugstore workers
E. Acetate ions revealed that one of the pharmacists
had bacteria of genus Staphylococcus.
78. During gravimetric determination What morphological pecularities of mi-
of mass fraction of sulfate ions in the crobal cell arrangement are typical for this
magnesium sulfate preparation precipi- genus?
tation is performed by means of bari-
um chloride solution. Precipitated barium A. They are arranged in form of bunch of
sulfate should be rinsed with: grapes
B. They are arranged in form of a chain
A. Diluted solution of sulfate acid C. They are arranged isolatedly
B. Distilled water D. They are arranged in pairs
C. Solution of barium chloride E. They are arranged in tetrads
D. Solution of sodium sulfate
E. Solution of hydrochloride acid 84. Crude herbal drugs must be examined
for yeastlike fungi. What agar can ensure
79. A patient has bradycardia, moderate development of these microorganisms so
hypotension, decrease of basal metaboli- that associating microflora will grow very
sm, edemata. What abnormality can slowly or won’t grow at all?
induce such syndrome?
A. Sabouraud’s peptone agar
A. Thyroid hypofunction B. Endo agar
B. Parathyroid hypofunction C. Meat infusion agar
C. Thyroid hyperfunction D. Milk-salt agar
D. Parathyroid hyperfunction E. Blood agar
E. Adrenal hypofunction
85. A patient took maximally deep breath.
80. A patient suffering from chronic Air volume being in lungs under these
Krok 1 Pharmacy 2008 9
D. A.
B.
E.
C.
A. Gluconeogenesis A. Ascorutinum
B. Glycogenolysis B. Thiamine hydrochloride
C. Oxidation of fatty acids C. Cyanocobalamin
D. Ketogenesis D. Nicotinic acid
E. Glycolysis E. Pyridoxine hydrochloride
103. An electrode composed by scheme 109. What form of hypoxia develops duri-
Au3+ | Au relates to the following type: ng shock and collapse?
A. I type electrodes A. Circulatory
B. II type electrodes B. Respiratory
C. III type electrodes C. Hypoxic
D. Oxidation-reduction electrodes D. Hemic
E. Ion-selective electrodes E. Tissue
104. You need to prepare ammoniac 110. Employees of a physicochemical
buffer solution. For this purpose you laboratory prepared water solutions of
should add the following solution to the urea, glucose, sodium sulfate, aluminium
water solution of ammonia: sulfate and sodium benzoate all of which
had the same molar concentration. What
A. Solution of ammonium chloride solution has the highest osmotic pressure
B. Solution of chloride acid under 298o K?
C. Solution of sulfate acid
D. Solution of potassium chloride A. Aluminium sulfate
E. Solution of sodium sulfate B. Urea
C. Glucose
105. Alkadiene is a name for aliphatic D. Sodium benzoate
carbohydrates with double bonds. Choose E. Sodium sulfate
a general formula for homologous series
of alkadienes: 111. Potassium dichromate K2 Cr2 O7 is
applied as oxidant in acidic medium. What
A. Cn H2n−2 is the product of reduction of dichromate-
B. Cn H2n+2 ion Cr2 O72− under these conditions?
C. Cn H2n
D. Cn H2n+ 1 A. Cr 3+
E. Cn H2n−1 B. Cr(OH)3
C. Cr(OH)2
106. Urea is a derivative of carbonic acid. D. [Cr(OH)6]3−
Choose a denomination of urea: E. Cr2 O3
A. Diamide of carbonic acid 112. Blood analysis revealed rise of acti-
B. Monoamide of carbonic acid vity of LDH1 , LDH2 , aspartate ami-
C. Ethylic ether of carbamic acid notransferase, kreatine phosphokinase-
D. Diethylic ether of carbonic acid MB. Biochemical disorder is observed in
E. Dimethylic ether of carbonic acid the following organ:
107. Choose a pair of substances that A. Heart
can be used for standardization of 0,1 M B. Skeletal muscles
solution of KMnO4 : C. Kidneys
A. Na2 C2 O4 , H2 C2 O4 D. Liver
B. K2 CO3 , CH3 COOH E. Pancreas
C. CH3 COOK, H2 C2 O4 113. Limited swelling of gelatine comes to
D. KHC2O4 , HCOOH
E. Na2 C2 O4 , CH3 COOH unlimited one (solution formation) under
the following conditions:
108. A patient complains about gingival
haemorrhage, petechial haemorrhages. A. Heating
What vitamin preparation should be B. Cooling
recommended? C. In presence of SO42 ions
D. In presence of Cl ions
E. If pH medium matches with isoelectric
point
Krok 1 Pharmacy 2008 12
114. What compound will be produced 119. You are given 0,05 M solution of
during reduction of methyl ethyl ketone? versene. What is standard substance for
standardization of this solution?
A. Metallic zinc
B. Sodium tetraborate
C. Sodium hydroxide
D. Oxalic acid
E. Potassium dichromate
A. secondary-butyl alcohol
B. Butanol-1 120. A 56 year old patient complains
C. Isobutyl alcohol about limitation of movements and pain
D. tertiary-butyl alcohol in hand joints, mainly at night. Objecti-
E. Propanol-2 vely: there is a disfiguring painful swelling
of affected joints. Blood and urine have
115. A female patient has been treated wi- high concentration of uric acid. What di-
th antibiotics for a long time. Thereafter sease has developed?
examination of smears form vaginal
secretion revealed oval cells with well- A. Gout
defined nucleus, some cells gemmate. B. Pellagra
What preparations can help to confirm C. Phenylketonuria
the diagnosis "candidosis"? D. Alkaptonuria
E. Tyrosinosis
A. Antifungal
B. Antibacterial 121. Electronic microscopy of a cell
C. Antichlamydial revealed mitochondrial destruction. What
D. Antiviral processes are disturbed?
E. Antiprotozoal A. ATP synthesis
116. One of mass production drugs is B. Protein biosynthesis
produced by inactivation of bacterial C. Glycolysis
exotoxin by formalin. What is this drug D. Synthesis of nucleic acids
for? E. Fat synthesis
A. Gastrin A. HCl
B. Vasointestinal polypeptide B. HCN
C. Neurotensin C. H2 CO3
D. Somatostatin D. CH3 COOH
E. Insulin E. H2 SO3
152. What denomination corresponds wi- 157. What is oxidation number of the
th the given formula? central atom in the compound H[AuCl4 ]?
A. +3
B. 0
C. +1
D. +2
E. +4
A. Benzo [b] pyridine 158. A child got burn on his hand caused
B. Benzo [b] pyrone-4 by hot water. Burn skin is bright red. What
C. Imidoazopyrimidine disturbance of local blood circulation is it?
D. Pyrazinopyrimidine
E. Benzothiazole A. Arterial hyperemia
B. Venous hyperemia
153. According to the IUPAC C. Stasis
nomenclature the given compound has D. Thrombosis
the following denomination: E. Embolism
159. A plantation of medicinal plants was
affected by a disease that caused yellow
spots and necrotic areas on leaves. Jui-
ce of affected plants remains infectious
even after bacterial filtration but after its
A. 1, 2, 3 − propanetriol inoculation on cultural medium growth of
B. 1 − propanol causative agent wasn’t observed. Causati-
C. 2 − propanol ve agent of this disease relates most
D. 1 − propanethiol probably to the following group of plant
E. 1, 2 − propanediol pathogenic microorganisms:
154. A 13 year old child complains A. Viruses
about poor appetite, pain in the right B. Fungi
subcostal area. Microscopical examinati- C. Actinomycetes
on of duodenal contents revealed big D. Bacteria
pyriform cells with two nuclei. What mi- E. Mycoplasma
croorganism was revealed?
160. It is known that a peroral drug contai-
A. Lamblia ns over 1 billion of living microbal cells
B. Trichomonad per 1 millilitre. Nonetheless the drug was
C. Amoeba accepted as applicable. What drug group
D. Trypanosoma does it relate to?
E. Toxoplasma
A. Eubiotics
155. Systems relate to colloid-disperse B. Antibiotics
ones if size of their particles is within the C. Vitamins
following range: D. Sulfanilamides
E. Immunostimulants
A. 10−9 – 10−7 m
B. 10−7 – 10−4 m 161. Microscopical examination of a leaf
C. > 10−4 m revealed water stomata on its serration.
D. ≶ 10−9 m These stomata are for exudation of liquid-
E. 10−9 – 10−4 m drop moisture. This process is called:
156. 0,1 M solution of the following acid
has the highest concentration of hydrogen
ions:
Krok 1 Pharmacy 2008 17
A. Guttation A. Ischemia
B. Gas exchange B. Thrombosis
C. Internal secretion C. Embolism
D. Transpiration D. Arterial hyperemia
E. Photosynthesis E. Venous hyperemia
162. A man has symptoms of cardi- 167. Choose an appropriate indicator for
ovascular atherosclerosis. The most fixation of titration end point in method
probable characteristic of this state will of bromatometry:
be growth of the following biochemical
value: A. Methyl red
B. Phenolphthalein
A. Concentration of low-density li- C. Starch
poproteins D. Methyl blue
B. Concentration of high-density li- E. Tropeolin 00
poproteins
C. Concentration of chylomicrons 168. Decarboxylation of 5-hydroxytryptophane
D. LDH5 activity gives origin to a certain biogenic ami-
E. Activity of pancreatic lipase ne with vasoconstrictive action. What bi-
ogenic amine is it?
163. Presence of the following ion of d-
elements in solutions can be exploited by A. Serotonin
means of K4 [F e(CN)6 ]: B. Histamine
C. Gamma-aminobutyric acidc
A. F e3+ D. Putrescine
B. Zn2+ E. Cadaverine
C. Cr 3+
D. Ni2+ 169. An annual plant of the Asteraceae
E. Cu2+ family has tripartite leaves, apical
anthodia with tubular flowers, flat
164. Sol is one of drug forms. What achenocarps that are tenent due to 2-3
happens if sols are fused with oppositely bristly serratures. This plant is:
charged granules?
A. Bidens tripartita
A. Mutual coagulation B. Chamomilia recutita
B. Thixotropy C. Centaurea cyanus
C. Sedimentation D. Echinacea purpurea
D. Contraction E. Artemisia vulgaris
E. Lyophilization
170. Crop production includes cultivation
165. A patient has obstructive respiratory of medicinal essential oil plants that don’t
failure. Name a disease that is usually grow in Ukraine wildely, namely Mentha
accompanied by such type of respiratory piperita, Ortosiphon stamineus, and also:
failure:
A. Salvia officinalis
A. Bronchial asthma B. Origanum vulgare
B. Pneumonia C. Leonurus cardiaca
C. Exudative pleuritis D. Thymus serpyllum
D. Pneumoconiosis E. Leonurus quinquelobatus
E. Pneumothorax
171. A patient was admitted to the infecti-
166. A patient is 54 year old. After intense ous department of a hospital. His provisi-
emotional stress he felt strong pain behi- onal diagnosis was "acute gastroenteritis".
nd his breastbone irradiating to his left Inoculation of feces on bismuth-sulfite
arm and left part of his neck. He felt also agar induced growth of black colonies wi-
death anxiety and broke into a cold sweat. th metallic glitter. What microorganisms
Nitroglycerine relieved pain. Name a di- should you think of?
sturbamce of local blood circulation in
heart that has developed in this case: A. Salmonellae
B. Escherichia
C. Shigella
D. Yersinia
E. Brucella
Krok 1 Pharmacy 2008 18
D.
E.
A. Indole
B. Bilirubin A. Proline hydroxylase
C. Lactate B. Alanine aminotransferase
D. Kreatine C. Pyruvate carboxylase
E. Glucose D. Tryptophane hydroxylase
E. Glutaminase
177. A patient takes blocker of muscari-
nic cholinoreceptors of parasympathetic 183. Low rate of vitamin B6 in the dietary
nerve organ synapses. What changes of intake leads to disturbance of protein
heart activity will be observed? metabolism. What biochemical processes
in the patient’s organism will become less
A. Heart rate rise active?
B. Heart rate and heart force fall
C. Heart rate fall A. Transamination
D. Heart force fall B. Reduction-oxidation
E. Prolongation of atrioventricular delay C. Phosphorilation
D. Methylation
178. Anxious condition can be characteri- E. Hydrolysis
zed by reduced salivation and sense of
dry mouth. What mediator is exuded out 184. During blowing up a baloon a boy
of nerve terminals innervating salivary took maximally deep and prolonged inspi-
glands? rations and expirations. Thereafter he
felt slight dizziness. What is the probable
A. Noradrenaline cause of this phenomenon?
B. Acetylcholine
C. Serotonin A. Drop of pCO2 in blood
D. Histamine B. Rise of pCO2 in blood
E. GABA C. Bronchi constriction
D. Arterial pressure rise
179. What mediator provides informati- E. Drop of pO2 in blood
on transmission from nerve terminations
of motoneurons to the fibers of skeletal 185. A child has got a burn. Burnt skin is
muscles? hyperemic, there are small vesicles full of
transparent fluid. What type of fluid is it?
A. Acetylcholine
B. Adrenaline A. Serous exudate
C. Noradrenaline B. Hemorrhagic exudate
D. Serotonin C. Purulent exudate
E. GABA D. Transsudate
E. Putrid exudate
180. Bacca fruit is typical for the following
representative of Solanaceae family: 186. As a result of reaction of mercury
excess with diluted nitric acid the followi-
A. Atropa belladonna ng gas will escape:
B. Hyoscyamus niger
C. Datura stramonium A. NO
D. Nicotiana tabacum B. NH3
E. Datura innoxia C. N2
D. N2 O
181. A male patient has pain in the right E. -
subcostal area, acholic feces. Decolourati-
on of feces is caused by deficiency of: 187. A biological system (living organism)
exchanges material and energy with the
A. Stercobilin environment. What system does it relate
B. Hemoglobin to?
C. Bilirubin
D. Bile acids A. Open, heterogenous
E. Skatole B. Isolated, heterogenous
C. Closed, homogenous
182. A patient is 50 years old. Ad a result D. Closed, heterogenous
of continuous improper feeding he got E. Open, homogenous
hypovitaminosis C. Lesion of connecti-
ve tissue is caused by low activity of the 188. A patient has been suffering from di-
following enzyme: abetes mellitus for 10 years. He was deli-
Krok 1 Pharmacy 2008 20