DSX 412

Blood Diseases
 ‫مكونات الدم‬
Blood Constituents
Blood Constituents
Blood Constituents
Red Blood Cells (RBCs)
 Red Blood Cells

Normal Red Blood Cells Under Light Microscope

 Red Blood Cells

Normal Red Blood Cells Under Microscope

Platelets
White Blood Cells (WBCs)
Neutrophils
 Neutrophils

Neutrophils
Granulated Cytoplasm + Nucleus is multi-lobed which are connected by thin strands of nuclear material.
Eosinophils
 Eosinophils

Eosinophils
* Cytoplasm contains large acidophilic granules (Appear Pink or Red).
* Nucleus often has two lobes connected by a band of nuclear material - Appears like a Telephone Receiver.
Basophils
 Basophils

Basophils
* The nucleus usually consists of two lobes which are often masked by cytoplasm granules.
* Cytoplasm contains granules which Stain deep blue to purple + Often numerous & mask the nucleus + contain
& Heparin.
Lymphocytes
 Lymphocytes

Lymphocytes
- Agranular cells with very clear cytoplasm which stains pale blue.
- The Nucleus is large - Fills the cell leaving a very thin rim of cytoplasm and dark purple.
Lymphocytes
Lymphocytes
Monocytes
 Monocytes

Monocytes
* Agranular Cells + The largest of leukocytes.
* The Nucleus often "U" OR kidney bean shaped.
* Cytoplasm stains light blue.
 Macrophage

Monocytes develop into Macrophage cell When migrate they from the bloodstream into the
tissue and undergo differentiation.
Anaemia
Anaemia
‫أنواع فقر الدم‬
Anaemia Types
Anaemia
Iron Deficiency Anaemia (IDA)
Iron Deficiency Anaemia (IDA)
Iron Deficiency Anaemia (IDA)
 ‫فقر الدم بالعوز الفيتاميني‬
Vitamin Deficiency Anaemia
Megaloblastic Anaemia
Vitamin Deficiency Anaemia / Megaloplastic Anaemia
Vitamin Deficiency Anaemia / Megaloplastic Anaemia
Vitamin Deficiency Anaemia / Megaloplastic Anaemia
Vitamin Deficiency Anaemia / Megaloplastic Anaemia
Vitamin Deficiency Anaemia / Megaloplastic Anaemia
 ‫فقر الدم اإلنحاللي‬
Haemolytic Anaemia
Haemolytic Anaemia
Hereditary Spherocytosis
Hereditary Spherocytosis

RBCs are Spheroid& Smaller than the Normal RBCs size.

Hereditary Spherocytosis
Sickle Cell Disease/ Anaemia
 Sickle Cell Disease/ Anaemia

RBCs are Sickle in shape + Fragile + Clump together in small vessels.

Sickle Cell Disease/ Anaemia
Sickle Cell Disease/ Anaemia
Autoimmune Haemolytic Anaemia
 ‫ سرطان الدم‬/‫ابيضاض‬
Leukaemia/ Blood Cancer
Leukaemia
Leukaemia
 ‫‪Leukaemia‬‬

‫ابيضاض دم حاد‪ /‬غير لمفاوي‪ /‬نقيوي‪ /‬نخاعيني‬

‫ابيضاض دم مزمن‪ /‬غير لمفاوي‪ /‬نقيوي‪ /‬نخاعيني‬

Leukaemia
Acute Leukaemia
Acute Leukaemia
Acute Leukaemia
Chronic Leukaemia
Chronic Leukaemia
Chronic Leukaemia
Chronic Leukaemia