BACCAY, Leia Angelie

DAMGO, Melchizedek
NADURA, Riscia

ChE 133 – Case Study

Topic: Chromatographic Separations of Biological and Pharmaceutical Products

OUTLINE:
I. Introduction to Chromatography
A. Basics and Principles
B. Preparative Chromatography versus Analytical Chromatography
C. Chromatographic Methods and Techniques
i. Gas Chromatography
ii. Liquid Chromatography
D. Selection of Sorbents for Chromatography
E. Advantages and Disadvantages

II. Applications of Chromatography in Biological and Pharmaceutical Products

A. Ion Chromatography in Pharmaceutical Drug Analysis
B. Applications of Ion Chromatography in Biological Product Analysis
C. Determination of Vitamin Content and Food Nutritional Quality
D. Detection of Food Spoilage and Food Process Control
E. Detection of Food Additives
F. Applications in DNA fingerprinting
G. Separation of Chiral Compounds
H. Detection of Alcohol Presence in the Blood

III. Modern Studies

A. Use of Associated Chromatographic Techniques in Bio-Monitored Isolation of
Bioactive Monoterpenoid Indole Alkaloids from Aspidosperma ramiflorum
B. New Insights into Liquid Chromatography for more Eco-friendly Analysis of
Pharmaceuticals
C. New Analytical Spiral Tube Assembly for Separation of Proteins by Counter-current
Chromatography