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Case study: Human embryos that have their genomes altered

Purpose:Genome editing (also known as gene editing) refers to


a set of technologies that allow scientists to alter an organism's
DNA. These technologies enable the addition, removal, or
modification of genetic material at specific sites in the genome.
There have been several ways to genome editing developed.
CRISPR-Cas9, which stands for clustered regularly interspaced
short palindromic repeats and CRISPR-associated protein 9, is a
well-known example. The CRISPR-Cas9 technology has piqued
the scientific community's interest since it is faster, cheaper,
more accurate, and more efficient than existing genome editing
technologies.

The global challenge : A laboratory experiment aimed at repairing damaged DNA in human embryos
demonstrates what may go wrong with this form of gene editing and why prominent experts think it's
too dangerous to try. More than half of the time, the editing resulted in unforeseen consequences, such
as the loss of a whole chromosome or large portions of it.

Cardiomyopathy is one of several hereditary illnesses that a kid inherits from his or her parents. More
than 10,000 hereditary disorders may be avoided if dangerous genetic abnormalities were corrected.
There are several examples. Cystic fibrosis, Huntington's disease, and breast cancer have all been related
to BRCA gene mutations.

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