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‫ﺑﺳم ﷲ اﻟرﺣﻣن اﻟﺣﯾم‬

‫أھم اﻷﺳﺋﻠﺔ ﻓﻲ ﻣﺎدة اﻟوراﺛﺔ اﻟﺑﺷرﯾﺔ ﻟﻠدﻛﺗورﺻﺎﻟﺢ ﺣﺳن‬

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Chapter 1

1. Nucleotide consist of :
A. Nitrogen base + Pentose sugar + phosphate group
B. Nitrogen base+ hexose sugar + phosphate group
C. Nitrogen base + phosphate group + triose sugar
D. Nitrogen + phosphate group + triose sugar
2. Purines are :
A. Adenine + Guanine
B. Thymine + Cytosine
C. Adenine+ Thymine
D. Uracil + Thymine
3. The Pentose sugar that presence in DNA
A. Ribose
B. Glucose
C. Xylose
D. Deoxy ribose
4. The nucleotides in nucleic acid are joined by :
A. Glycoside bond
B. Phosphodiester bond
C. Hydrogen bond
D. Peptide bond
5. If the order of bases along one strand of DNA is ( AGGTTACTGCAC ) the complementary strand will be :
A. AGGTTACTGCAC
B. AGGTCCCGCAC
C. TCCAATGACGTG
D. AGGOOOOGCAC

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6. The DNA strands in the double helix are _______________ knowing the sequence of one strand dictates the sequence of the
opposite strand :
A. Base pair
B. Complementary
C. Antiroll
D. Anti parallel

7. The capped on 5/p- terminus in mRNA is important because :


A. Recognize of mRNA by translating machinery
B. Stabilize mRNA against 5/-exonucleases
C. A &B
D. Non of the above

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8. The differences between DNA & RNA are :
Differences DNA RNA
Types of base Thymine &Cytosine Uracil & Cytosine
Adenine & Guanine Adenine & Guanine

Number of Double stranded Single stranded


strands

Size Large in size Smaller than DNA

site Inside nucleus Cytoplasm mainly

Number of Millions of base paring 100 – 5000 bases


bases

Types A, B, Z mRNA, rRNA, tRNA

Type of sugar Deoxy Ribose Ribose

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Chapter 2

1. Drow a flow chart to show how to get from :


A. Gene – RNA – Protein – trait .
B. Genome – DNA - Protein – trait .
C. mRNA - Protein – trait .
D. tRNA - Protein – trait .

2. The process of one strand of each daughter DNA comes from the parent DNA and one

strand is new called :

A. Conservative replication
B. Many conservative replication
C. Original copy replication
D. semi-conservative replication
3. DNA replication takes place in
A. G1 phase
B. S phase
C. G2 phase
D. Mitosis
4. series of short segments on the lagging strand are called:
A. Okazaki Fragments
B. DNA fragment
C. Lagging fragment
D. Crick fragment

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5. The double helix of DNA is very important because :
A. Its srmi-conservative
B. To transfer the genetic information to future generations
C. To avoid mutations
D. All of the above
6. ___________catalyze unwinding by disruption of hydrogen bonding between complementary bases
A. Ligase
B. DNA polymerase
C. Helicase
D. RNA Polymerase
7. The enzyme which joined okazaki fragment
A. Ligase
B. DNA polymerase
C. Helicase
D. RNA Polymerase

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Chapter 3,4,5

1. If this strand code for DNA ( 5’ GCGATATC 3’ ) what is the expected mRNA strand :
A. 5’ GGUAUCCG 3’
B. 5’ AAUAUCCG 3’
C. 3’ GGUAUCCG 5’
D. 3’CGCUAUAG5’
2. The cell adds _________to one end of mRNA , and _______to the other end. These both function to protect the mRNA from
enzymes that would degrade
A. Poly A& B tails
B. a protective cap , a tail of A’s
C. Poly g& B tails
D. a protective cap , a tail of U’s
3. The genome is count by _________ unite :
A. Meter
B. Second
C. Sedimentation
D. BP
4. All the genetics molecules are read from :
A. 3’ to 5’
B. 5’ to 3’
C. 2’ to 3’
D. 2’ to 5’
5. Exons are :
A. Non-coding sequence of the gene which separate the coding regions
B. Coding sequence that codes for a protein
C. Sequence with variable length that does not contain stop codons .

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D. Non of the above

6. introns are :
A. Non-coding sequence of the gene which separate the coding regions
B. Coding sequence that codes for a protein
C. Sequence with variable length that does not contain stop codons .
D. Non of the above
7. The open reading frame is:
A. Non-coding sequence of the gene which separate the coding regions
B. Coding sequence that codes for a protein
C. Sequence with variable length that does not contain stop codons .
D. Non of the above
8. Transcription occurs in :
A. In the nucleus
B. In the cytoplasm
C. In the ribosome
D. Non of the above
9. Translation occurs in :
A. In the nucleus
B. In the cytoplasm
C. In the ribosome
D. Non of the above
10. RNA processing occurs in :
A. In the nucleus
B. In the cytoplasm
C. In the ribosome
D. Non of the above

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Chapter 7

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Answers Key
Chapter 1 Chapter2 Chapter3,4,5
Question 1 A A D
Question2 A D B
Question3 D B D
Question4 B A B
Question5 C B B
Question6 B C A
Question7 c A C
Question 8 A
Question9 B
Question10 A
Question11
Question12
Question13
Question14

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