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OTC medications.12 Consumers’ knowledge of self- 169 refused to participate, giving a response rate of
medication was assessed by asking 4 questions with yes 76%. Most responders were male, the participants were
or no responses. A scoring system was designed in this predominantly in the age group (23-33 years), and were
study to determine consumers’ knowledge. A score of university graduates. A more detailed description of
one was given to a yes response, and a score of zero was socio-demographic characteristics is provided in Table 1.
given to a no response. The total score for knowledge Self-medication practice. A total of 285 medications
domain ranged from 0-4. The scores were summed, and were purchased without prescriptions. Of these,
the total knowledge score was calculated. A cut off level 139 (48.8%) medications should be dispensed by
of <2 was considered poor knowledge, and a score of ≥2 prescription only, and 146 (51.2%) were OTC and
was considered adequate knowledge of self-medication.
can be dispensed without prescription (Table 2). The
Consumers’ attitude toward self-medication was
assessed by asking 4 questions. The responses to the first most common prescription medications dispensed
and second questions were scored as follows: 0=never, without prescriptions were antibiotics and analgesics/
1=rarely, 2=occasionally, 3=sometimes, 4=frequently, antipyretics.
5=usually, 6=always; whereas the same scoring was Sources of information and reasons for self-
reversed for responses to the third and fourth questions medications. The most common sources of information
as shown in the results. The responses were summed stated were physicians and pharmacists (n=341, 80.2%),
and the total attitude score was calculated. The total medicine pamphlets (n=246, 58%), followed by friends
attitude score ranged from 0-24. A score of <12 was and family (n=113, 27%), and online sources (n=95,
considered negative attitude, and a score of ≥12 as 22%). Medication side effects (n=275, 65%), and
positive attitude toward self-medication. Perception medication use (n=273, 64%) were the most common
toward self-medication was assessed by asking 2 facts of information that participants were interested in
questions. The responses to the first question were scored knowing about their medications. The most common
as: 0=never, 1=rarely, 2=occasionally, 3=sometimes, reasons for buying medication without prescription was
4=frequently, 5=usually, 6=always; the responses to the that the symptoms were perceived to be too minor to
second question were reversed. The total score ranged consult a physician (n=227, 54%), followed by time
from 0-12. A cut of level of <6 was considered negative saving (n=167, 40%) and minor illnesses for which
perception, and a score of ≥6 was considered positive
perception.
Table 1 - Sociodemographic characteristics
Permission to conduct the study was obtained of 538 community pharmacy
from each pharmacy manager of the participating customers.
community pharmacies and the Research and Ethics
Committee at the College of Pharmacy, King Saud Variables Frequency )%(
University, Riyadh, Saudi Arabia. Data collectors gave Region
a brief introduction to the consumers by explaining the North 88 (16.4)
South 96 (17.8)
aims and significance of the study. Verbal consent was
Middle 133 (24.7)
obtained from all participants. Confidentiality of data East 114 (21.2)
was maintained throughout the study. West 107 (19.9)
We utilized the Statistical Package for Social Sciences Age
(SPSS Inc., Chicago, IL, USA) version 18 to analyze 12-22 years 75 (13.9)
the study data. Results are displayed as counts and 23-33 years 188 (34.9)
34-44 years 163 (30.3)
percentages. Descriptive statistics were used to illustrate
45-55 years 85 (15.8)
respondents’ demographic characteristics, and list of >56 years 27 (5.0)
medication classes. Categorical variables were presented Gender
as count and percentages and continuous variables Male 392 (72.9)
as mean and standard deviation. The Shapiro-Wilk Female 146 (27.1)
test was used to test the distribution of the responses. Level of education
No formal education 24 (4.5)
Kruskal-Wallis Test or Mann Whitney Test was used
Elementary School 49 (9.1)
where appropriate. Intermediate School 22 (4.1)
High school 160 (29.7)
Results. Demographic characteristics. A total of Diploma 28 (5.2)
538 consumers visiting community pharmacies in University graduates 227 (42.2)
Riyadh city, participated in the survey while a further Postgraduates 28 (5.2)
the participants knew the treatment that was required that they always read the medication pamphlet, and
(n=168, 40%). only 156 (29.2%) participants believe that buying
Knowledge of self-medication. Based on the medication without prescription is not safe practice
knowledge total score, 375 (69.7%) participants had (Table 4).
poor knowledge (score of <2) regarding self-medication. Perception of self-medication. Based on the
A total of 367 (68.2%) participants did not know perception total score (0-12), most participants (321,
whether the medicine they bought is a prescription- 59.7%) had negative perception of self-medication. A
only or an OTC medication. It was interesting that total of 56 (21.3%) of the participants indicated that
44.5% of consumers did not tell the pharmacist of other the pharmacist does not provide information on drug
interactions for the medications they purchased without
medications they use at home at the time of buying
prescription and their current medications (Table 5).
medications without prescription (Table 3).
Association of demographic characteristics
Attitude toward self-medication. Based on the with knowledge, attitude, and perception. Among
attitude total score (0-24), 337 (62.6%) participants had demographic characteristics, occupation was
positive attitude (score of ≥12) toward self-medications. significantly associated with the mean knowledge score
However, a total of 166 (43.7%) participants indicated (p=0.044). Whereas, education level (p<0.001), and
occupation (p=0.013) were significantly associated with
Table 2 - Medications bought without prescriptions among 285 the mean perception score (Table 6). A post hoc analysis
consumers from community pharmacies. revealed that those who are employed had a statistically
significantly higher mean knowledge score than
Medications Prescription only OTC students. Those who had a diploma had a statistically
medications medications
Total 139 (48.8) 146 (51.2) significant lower mean perception score than those who
Analgesics/antipyretics 27 (19.4) 61 (41.8) had a university level of education.
Cough preparations 4 (2.9) 27 (18.5)
Antibiotics 31 (22.3) 0 Discussion. The results revealed several interesting
Anti-allergy 10 (7.2) 15 (10.2) findings regarding the knowledge, attitudes, and
Vitamins 2 (1.4) 10 (6.8)
perception of self-medication among consumers
Anti-diabetics 9 (6.5) 0
Cardiovascular medications 8 (5.8) 0
attending community pharmacies in Riyadh city.
Antiulcer 1 (0.7) 7 (4.8) Almost half of the medications that consumers bought
Oral contraceptives 7 (5.0) 0 from community pharmacies without a prescription
Eye/ear drops 4 (2.9) 2 (1.4) were actually prescription-only medications, and 45%
Dermatology preparations 3 (2.2) 2 (1.4) of the participants did not tell the pharmacist of the
Antifungal 4 (2.9) 0
prescribed medication(s) that they were using at
Antidepressants 4 (2.9) 0
Asthma medications 4 (2.9) 0 home. Overall, most participants had poor knowledge,
Antidiarrhea 1 (0.7) 1 (0.7) positive attitude, and negative perception toward
Others 20 (14.3) 21 (14.4) self-medications. Information regarding medications
Data are expressed as number and percentage (%), was most commonly obtained from a physician and
OTC - over the counter
pharmacist, medicine pamphlets, followed by friends
and family, and online sources. Minor illnesses, time
Table 3 - Knowledge of self-medication among 538 consumers visiting saving, and perceived knowledge, and treatment
the community pharmacies in Riyadh city, Saudi Arabia.
of disease were common reasons for seeking self-
Knowledge items Yes No
medication.
Do you know whether the medicine you just 171 (31.8) 367 (68.2) Several studies have been conducted on self-
purchased needs a prescription or not? medication worldwide. A study by Bawazir (1992)5
Do you know the route of administration, 260 (64.8) 141 (35.2) in Riyadh showed that 35% of medications bought
dosage, and side effects of the medicine you
purchased without a prescription?
by patients from community pharmacies without
Have you ever used prescription medications 48 (18.1) 217 (81.9) a prescription were prescription only medications;
along with medications you purchased however, in the current study, after 2 decades, we
without prescription? found a higher rate. A study in Tanzania found that
When you buy a medication without a 96 (55.5) 77( 44.5)
prescription, do you tell the pharmacist of 37% of medications requested by customers without
other medications you use at home? a prescription from community pharmacies were
Data are expressed as number and percentage (%) prescription only medications,4 which is lower than our
Table 6 - The mean scores of knowledge, attitude, and perception among consumers’ demographic
characteristics in Riyadh city, Saudi Arabia.
Demographic Knowledge score P-value Attitude score P-value Perception score P- value
characteristics Mean± SD Mean± SD Mean± SD
Age* 0.052 0.161 0.145
12-22 years 0.80±0.78 12.01±4.42 4.44±3.70
23-33 years 1.06±0.89 13.20±4.70 4.39±3.57
34-44 years 1.19±1.04 13.71±4.97 4.61±3.65
45-55 years 1.00±0.95 12.90±4.90 3.36±3.39
>56 years 1.25±0.94 13.40±5.68 4.62±3.24
Gender** 0.272 0.410 0.629
Male 1.09±0.93 13.06±4.79 4.27±3.52
Female 0.99±0.98 13.40±4.98 4.44±3.74
Level of education* 0.058 0.300 <0.001
Illiterate 0.08±1.01 11.16±4.17 3.79±2.46
Primary School 0.93±0.87 12.44±4.10 5.16±3.43
Intermediate 1.18±0.85 13.04±4.99 5.40±4.27
School
High school 0.60±0.73 13.39±4.56 4.33±3.60
Diploma 1.09±0.94 12.39±5.21 1.42±2.98
University graduate 1.10±0.96 13.38±5.09 4.44±3.57
Postgraduates 1.21±1.10 13.71±5.41 4.21±3.43
Occupation* 0.044 0.288 0.013
Student 0.91±0.89 12.33±4.50 4.09±3.60
Employed 1.16±0.98 13.43±4.86 4.09±3.52
Unemployed 0.90±0.88 13.19±4.94 4.83±3.76
Retired 1.27±0.88 12.31±5.56 4.09±2.97
Others 0.91±0.82 13.15±4.84 6.13±3.58
Total 1.06±0.94 13.15±4.84 4.31±3.58
Kruskal-Wallis test*, Mann-Whitney Test**
study findings. A study from Kuwait,6 a neighboring governing the sale of prescription only medications
country of Saudi Arabia, investigating self-medication without a prescription. Pharmacists should be
among adolescents reported that the main source of instructed not to sell prescription medications without
information regarding medications was the parents. prescription. In addition, educational workshops for
This is also consistent with the findings of our study in pharmacists and undergraduate pharmacy curriculum
which family and friends were one of the most common updates are necessary to ensure appropriate community
sources of medication information. In Bahrain, another pharmacy practice regarding the sale of prescription/
neighboring country, it was found that the most non-prescription medications.
common reasons for seeking self-medication were Irresponsible self-medication is common in Saudi
time saving, involved minor illness that does not need Arabia. Sources of information were not appropriate,
a visit to a doctor, and cost saving.7 This was similar and knowledge and perception of self-medication were
to our findings with the exception of financial reasons, inadequate. Community pharmacists should take the
as only 9% of respondents in our study sought self- initiative to actively counsel consumers and provide
medication due to financial difficulties. Our study information regarding possible drug interactions when
revealed that around 45% of the participants did not dispensing medications. Educational campaigns for
inform the pharmacist of other medications that they the public on self-care, and responsible self-medication
used at home. This is similar to a finding from a recent should be strengthened. Future studies should focus on
study in Malaysia,13 in which it was reported that 60% improving the consumers’ awareness of self-medication
of community pharmacy customers did not inform the
and the proper use of medications.
pharmacist of prescription medications that they used
Our study has several limitations that can limit
at home.
the generalization of the findings. Although we used
The unauthorized prescribing of antibiotics is
associated with multiple-drug resistance and therefore, a standard sampling method, selection bias could be
they must be prescribed under physician advice.14 Our present as not all community pharmacies in Riyadh
results suggest that the practice of community pharmacy were included. In addition, almost three-quarters of the
customers in Saudi Arabia regarding antibiotic use has participants were male due to the social consideration
not changed over the past 2 decades. The frequency of in Saudi Arabia as females rarely visit community
dispensing antibiotics without a prescription reported pharmacies and tend to send their male relatives or
in our study (22.3%) was the same as that (20.9%) in drivers to buy their medications. The most common
a study conducted in 1992 in Riyadh.5 Another recent source of information mentioned by the consumers
study in Riyadh using simulated clinical scenarios was physicians and pharmacists; however, we could
reported that 78% of community pharmacies in Saudi not clearly distinguish between them. We could not
Arabia dispense antibiotics without prescriptions.14 In ascertain if patient economic status was contributing
Spain,15 a simulation study reported that the prevalence to self-medication because patient monthly income
of antibiotics dispensing without prescription for data was not collected. In addition, the study was
urinary tract infection was 79.7%, 34.8% for sore conducted in the summer and perhaps if similar study
throat, and 16.9% for bronchitis.16 Another simulation was conducted in the winter the prevalence might be
study from Europe reported that Ciprofloxacin was higher as many consumers visit community pharmacies
dispensed without prescription in 53% of the cases.17 asking for antibiotics to treat cold symptoms.
The study emphasizes several aspects of medication
safety with regard to self-medication. Benefits, risks, References
and precautions of self-medication need to be explained
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