Professional Documents
Culture Documents
Theories of Aging PDF
Theories of Aging PDF
AGING
Margie T. Molina, RN, MAN
BIOLOGICAL THEORIES OF AGING
1. Stochastic Theory
= the effects of aging are primarily due to genetic
defects, development, environment, and the inborn
aging process .
2. Nonstochastic Theory
= are founded on a programmed perspective that is
related to genetics or one’s biological clock.
Stochastic Theory
Stochastic Theory
1. Free Radical Theory
aging is due to oxidative metabolism and the
effects of free radicals, which are the end products
of oxidative metabolism
Membranes, nucleic acids, and proteins are
damaged by free radicals, which causes cellular
injury and aging.
Free Radical Theory
Causes:
Causes:
immune heart
disease disease
2. Wear and Tear Theory
- focuses on the process of metabolic waste product
accumulation or nutrient deprivation that damages
DNA synthesis, which, in turn, results in molecular
and organ malfunction.
- it states that each person’s body has a “master
clock” that controls these cells and organs, which
slows down with time
Wear and Tear Theory
Stress Factor such as:
Smoking and alcohol abuse
radiation,
Muscle strain
UV light
3. Orgel/ErrorTheory
- over time, cells accumulate errors in their DNA and
RNA protein synthesis that cause the cells to die.