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  • OBA MSK Physio

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    Manusha Selvarajoo
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    The document contains 4 multiple choice questions about muscle physiology mechanisms: 1) The long-distance athlete experiencing a muscle cramp is most likely affected in the binding of calcium to troponin which exposes the actin binding site. 2) Calcium release in the myofibrils during muscle contraction is facilitated by ryanodine receptors located in the sarcoplasmic reticulum. 3) A drug selectively inhibiting smooth muscle contraction would target myosin, the motor protein involved in muscle shortening. 4) Myosin is the most important muscle protein for skeletal muscle contraction, as it powers the sliding of actin filaments.

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    OBA-MSK-physio

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    The document contains 4 multiple choice questions about muscle physiology mechanisms: 1) The long-distance athlete experiencing a muscle cramp is most likely affected in the binding of calcium to troponin which exposes the actin binding site. 2) Calcium release in the myofibrils during muscle contraction is facilitated by ryanodine receptors located in the sarcoplasmic reticulum. 3) A drug selectively inhibiting smooth muscle contraction would target myosin, the motor protein involved in muscle shortening. 4) Myosin is the most important muscle protein for skeletal muscle contraction, as it powers the sliding of actin filaments.

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    8 views1 page

    OBA MSK Physio

    Uploaded by

    Manusha Selvarajoo
    The document contains 4 multiple choice questions about muscle physiology mechanisms: 1) The long-distance athlete experiencing a muscle cramp is most likely affected in the binding of calcium to troponin which exposes the actin binding site. 2) Calcium release in the myofibrils during muscle contraction is facilitated by ryanodine receptors located in the sarcoplasmic reticulum. 3) A drug selectively inhibiting smooth muscle contraction would target myosin, the motor protein involved in muscle shortening. 4) Myosin is the most important muscle protein for skeletal muscle contraction, as it powers the sliding of actin filaments.

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    Course assessment Physiology

    1.A long-distance athlete is having a muscle cramp after running continuously for 5 km.
    Which of the following mechanisms of skeletal muscle contraction is most likely to be
    affected in this athlete?
    A. Bending of the myosin head with release of ADP and phosphate.
    B. Binding of calcium to troponin which exposes the actin binding site.
    C. Binding of the new ATP to the myosin head.
    D. Formation of cross-bridge between myosin head and actin

    2.Calcium needs to be released in the myofibrils in order to maintain the skeletal muscle
    contraction. Which of the following structures most likely facilitates calcium release as
    mentioned in the statement above?
    A. Calcium pump
    B. Dihydropyridine receptor
    C. Ryanodine receptors
    D. T-tubules

    3.In an experiment, a drug is used to selectively inhibit the protein involved in smooth muscle
    contraction.
    Which of the following proteins is most likely to be inhibited in the above situation?
    A. Calmodulin
    B. Actin
    C. Myosin
    D. Tropomyosin

    4.Which of the following muscle proteins is most important for the contraction of skeletal
    muscle?
    A. Myosin
    B. Titin
    C. Tropomyosin
    D. Troponin

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