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Case Presenttaion (GRP 1, 3BSN-13) Ra (2NCP)
Case Presenttaion (GRP 1, 3BSN-13) Ra (2NCP)
College of Nursing
College of Allied Health Sciences
Arellano St., Dagupan City
RHEUMATOID ARTHRITIS
Presented by:
Buenaobra, Ronaldino D.
Cachero, Danna Kate C.
Cerame, Clarisse B.
Corpuz, Lorelyn S.
Cuña, Audrey T.
Presented to:
Prof. Carol Joy Paragas, RN, MAN
CONTENTS
I. INTRODUCTION
Case Scenario
IV. CONCLUSION
V. RECOMMENDATION
INTRODUCTION
Case Scenario
Upon arrival at the Emergency Room, her vital signs are as follows: BP=130/80
mmHg, HR= 86bpm, RR=22 cpm, T=37.8°C (100°F). On examination, her hands are
not grossly deformed but show mild ulnar deviation and swelling. It may be due to
excess joint fluid, thickening of the synovial lining, inflammation of surrounding soft
tissues, such as bursae and tendons, or bony enlargement. When palpated, the
patient’s hands and feet are tender, but no mass found on her joints. However, the fluid
is palpated as “boggy.” This can also be shown by her swelling hands and feet. She
appears restless, exhibiting guarded behavior. She reported a pain scale of 6/10.
She also reports constant fatigue and an intermittent low-grade fever. Her current
medications include: Naproxen (Aleve) 220 mg twice daily to relieve her symptoms. She
does not drink alcohol and has never smoked.
Brief Discussion of the Disease
Medical Management
Medical management is aligned with each phase of rheumatoid arthritis.
● Rest and exercise. There should be a balance of rest and exercise planned for a
patient with RA.
● Referral to community agencies such as the Arthritis Foundation could help the
patient gain more support.
● Biologic response modifiers. An alternative treatment approach for RA, biologic
response modifiers, has emerged, wherein a group of agents that consist of
molecules produced by cells of the immune system participate in the inflammatory
reactions.
● Therapy. A formal program with occupational and physical therapy is prescribed
to educate the patient about the principles of joint protection, pacing activities,
work simplification, range of motion, and muscle-strengthening exercises.
● Nutrition. Food selection should include the daily requirements from the basic
food groups, with emphasis on foods high in vitamins, protein, and iron for tissue
building and repair.
Pharmacologic Therapy
The drugs used in each phase of rheumatoid arthritis include:
Early Rheumatoid Arthritis
● NSAIDs. COX-2 medications block the enzyme involved in inflammation
while leaving intact the enzyme involved in protecting the stomach lining.
● Methotrexate. Methotrexate is currently the standard treatment of RA
because of its success in preventing both joint destruction and long-term
disability.
● Analgesics. Additional analgesia may be prescribed for periods of
extreme pain.
Moderate, Erosive Rheumatoid Arthritis
● Cyclosporine. Neoral, an immunosuppressant is added to enhance the
disease modifying effect of methotrexate.
Persistent, Erosive Rheumatoid Arthritis
● Corticosteroids. Systemic corticosteroids are used when the patient has
unremitting inflammation and pain or needs a “bridging” medication while
waiting for slower DMARDs to begin taking effect.
Advanced, Unremitting Rheumatoid Arthritis
● Immunosuppressants. Immunosuppressive agents are prescribed
because of their ability to affect the production of antibodies at the cellular
level.
● Antidepressants. For most patients with RA, depression and sleep
deprivation may require the short-term use of low-dose antidepressants
such as amitriptyline, paroxetine, or sertraline, to reestablish an
adequate sleep pattern and to manage chronic pain.
Surgical Management
For persistent, erosive RA, reconstructive surgery is often used.
● Reconstructive surgery. Reconstructive surgery is indicated when pain cannot
be relieved by conservative measures and the threat of loss of independence is
eminent.
● Synovectomy. Synovectomy is the excision of the synovial membrane.
● Tenorrhaphy. Tenorrhaphy is the suturing of a tendon.
● Arthrodesis. Arthrodesis is the surgical fusion of the joint.
● Arthroplasty. Arthroplasty is the surgical repair and replacement of the joint.
ANATOMY AND PHYSIOLOGY
The skeletal system is your body’s central framework. It consists of bones and
connective tissue, including cartilage, tendons, and ligaments. It’s also called the
musculoskeletal system.
Besides contributing to body shape and form, our bones perform several important body
functions.
1. Support. Bones, the “steel girders” and “reinforced concrete” of the body, form
the internal framework that supports the body and cradle its soft organs; the
bones of the legs act as pillars to support the body trunk when we stand, and the
rib cage supports the thoracic wall.
2. Protection. Bones protect soft body organs; for example, the fused bones of the
skull provide a snug enclosure for the brain, the vertebrae surround the spinal
cord, and the rib cage helps protect the vital organs of the thorax.
3. Movement. Skeletal muscles, attached to bones by tendons, use the bones as
levers to move the body and its parts.
4. Storage. Fat is stored in the internal cavities of bones; bone itself serves as a
storehouse for minerals, the most important of which are calcium and phosphorus;
because most of the body’s calcium is deposited in the bones as calcium salts,
the bones are a convenient place to get more calcium ions for the blood as they
are used up.
5. Blood cell formation. Blood cell formation, or hematopoiesis, occurs within the
marrow cavities of certain bones.
Anatomy and physiology of the affected part: Hands and Feet
Hand
The skeleton of the hand consists of carpals, the metacarpals, and the phalanges.
➔ Carpal bones. The eight carpal bones, arranged in two irregular rows of four
bones each, form the part of the hand called carpus, or, more commonly, the
wrist; the carpals are bound together by ligaments that restrict movements
between them.
➔ Metacarpals. The metacarpals are numbered 1 to 5 from the thumb side of the
hand to the little finger; when the fist is clenched, the heads of the metacarpals
become obvious as the “knuckles“.
➔ Phalanges. The phalanges are the bones of the fingers; each hand contains 14
phalanges; there are three in each finger (proximal, middle, and distal), except in
the thumb, which has only two proximal and distal.
Foot
The foot, composed of the tarsals, metatarsals, and phalanges, has two important
functions.; it supports our body weight and serves as a lever that allows us to propel our
bodies forward when we walk and run.
➔ Tarsus. the tarsus, forming the posterior half of the foot, is composed of seven
tarsal bones.
➔ Calcaneus and Talus. Body weight is carried mostly by the two largest tarsals,
the calcaneus, or heel bone, and the talus (ankle), which lies between the tibia
and the calcaneus.
➔ Metatarsals. Five metatarsals form the sole.
➔ Phalanges. 14 phalanges form the toes; each toe has three phalanges, except
the great toe, which has two.
➔ Arches. The bones in the foot are arranged to form three strong arches: two
longitudinal (medial and lateral) and one transverse.
Synovial Joints
Synovial joints are joints in which the articulating bone ends are separated by a joint
cavity containing a synovial fluid; they account for all joints of the limbs.
➔ Articular cartilage. Articular cartilage covers the ends of the bones forming the
joints.
➔ Fibrous articular capsule. The joint surfaces are enclosed by a sleeve or a
capsule of fibrous connective tissue, and their capsule is lined with a smooth
synovial membrane (the reason these joints are called synovial joints).
➔ Joint cavity. The articular capsule encloses a cavity, called the joint cavity, which
contains lubricating synovial fluid.
➔ Reinforcing ligaments. The fibrous capsule is usually reinforced with ligaments.
➔ Bursae. Bursae are flattened fibrous sacs lined with synovial membrane and
containing a thin film of synovial fluid; they are common where ligaments,
muscles, skin, tendons, or bones rub together.
➔ Tendon sheath. A tendon sheath is essentially an elongated bursa that wraps
completely around a tendon subjected to friction, like a bun around a hotdog.
Pathophysiology
The synovitis, swelling, and joint damage that characterize active RA are the end
results of complex autoimmune and inflammatory processes that involve components of
both the innate and adaptive immune systems. In a susceptible individual, the
interaction of environment and genes results in a loss of tolerance of self-proteins that
contain a citrulline residue. These proteins are generated via post-translational
modification of arginine residues to citrulline residues by the enzyme peptidyl arginine
deiminase.
DEPENDENT DEPENDENT
9. Begin 9. Methotrexate is a
methotrexate chemotherapeutic
(Rheumatrex) agent that is used as
therapy as ordered. a disease-modifying
antirheumatic drug
(DMARD) because it
has an
anti-inflammatory
effect, which reduces
symptoms in days to
weeks.
INTERDEPENDENT INTERDEPENDENT
/COLLABORATIVE /COLLABORATIVE
10. Assess the 10. Methotrexate can
patient’s periodic cause bone marrow
laboratory monitoring suppression and
(CBC, BUN, and liver hepatotoxicity.
panel).
Provide foam or
alternating pressure Decreases pressure
mattress. on fragile tissues to
reduce risks of
immobility and
development of
decubitus.
DEPENDENT DEPENDENT
Begin methotrexate Methotrexate is a
(Rheumatrex) chemotherapeutic
therapy as ordered agent that is used as
a disease-modifying
antirheumatic drug
(DMARD) because it
has an
anti-inflammatory
effect, which reduces
symptoms in days to
weeks.
INTERDEPENDENT/ INTERDEPENDENT/
COLLABORATIVE/ COLLABORATIVE/
DISCHARGE DISCHARGE
TEACHING TEACHING
Discuss with the Helps prevent
family about the accidental injuries
safety needs such as and falls.
raised chairs and
toilet seat, use of
handrails in the tub,
shower and toilet,
proper use of mobility
aids and wheelchair
safety.
RECOMMENDATIONS
Patients with rheumatoid arthritis need information about the disease in order to
be able to make self-management decisions and to cope with having a chronic
condition. It is essential for a patient to: identify particular areas of life affected by
disease; be educated on basic disease management and required lifestyle changes; be
capable of identifying elements of control over the disease symptoms and treatment.