Indian Journal of Rheumatology 2008 December

PG Forum
Volume 3, Number 4; p. 171

Rheumatology Quiz
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V Arya1, V Dhir2
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1. Oesophageal involvement in all of the following disor- (d) Anti-pegloticase antibodies develop in 75% of
ders is predominantly of the lower oesophageal sphincter patients
(LES) except 6. Ferri’s major classification criteria for mixed cryoglob-
(a) Inflammatory myopathy ulinemia include all except
(b) Rheumatoid arthritis (a) Low C4 levels
(c) Systemic lupus erythematous (b) Leukocytoclastic vasculitis
(d) Mixed connective tissue disease (c) Hepatitis C virus positivity
2. Vasculitic and atherosclerotic lesions on 18 FDG PET (d) Purpura
are distinguished by all the following except 7. The arthritis associated with Hepatitis C virus infection
(a) Atherosclerotic lesions appear as hot spots can be distinguished from rheumatoid arthritis by all
(b) Vasculitic lesions appear smooth and linear except
(c) Uptake of 18 FDG is more intense in vasculitic (a) Pattern of joint involvement
lesions (b) Non-erosive character
(d) Luminal flow is less in areas of vasculitic lesions (c) Lack of anti-CCP positivity
3. Which of the following is false for patellofemoral (d) Response to anti-viral therapy
osteoarthritis (OA)? 8. Which of the following is false about carcinomatous
(a) Osteophytes do not correlate with pain polyarthritis
(b) Lateral patellofemoral OA progression is more (a) Not associated with metastases/tumour extension
frequent than medial (b) Has an insidious onset
(c) Patellar subluxation predisposes to the condition (c) Lower limb predominance with sparing of wrists
(d) Valgus malalignment associates more strongly (d) Commoner in older patients
with patellofemoral OA than tibiofemoral OA 9. Erythromelalgia has the following characteristics except
4. Which of the following is false about Fractalkine, a new (a) Predominantly involves the feet
inflammatory marker (b) Often associated with thrombocythemia
(a) It is a chemokine of the CX3CL1 family (c) Exacerbated by cold
(b) Exists as both soluble and membrane bound forms (d) Best treated with aspirin
(c) Mostly implicated in the pathogenesis of RA 10. Which of the following is not a feature of Ehlers–Danlos
(d) Requires glycosaminoglycans for adhesion syndrome type IV
5. All the following are true regarding Pegloticase except (a) Hyperextensibility of large joints
(a) Potent uric acid lowering drug (b) Repeated arterial ruptures
(b) Given orally (c) Mitral valve prolapse
(c) Works by converting uric acid to allantoin (d) Spontaneous hemopneumothorax
For answers refer to page 173

1
Department of Medicine, JIPMER, Puduchery and 2Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences,
Lucknow, India.
Correspondence: Dr. V Arya, email: linuxphoenix@gmail.com
 What is your diagnosis? PG Forum 173

ACKNOWLEDGEMENT 2. Wisnieski JJ, Baer AN, Christensen J, Cupps TR, Flagg DN,
Jones JV, et al. Hypocomplementemic urticarial vasculitis
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Source of funding: Nil. syndrome. Clinical and serological findings in 18 patients.

Disclosure statement: Authors have declared no conflict of Medicine (Baltimore) 1995; 74: 24–41.
interest. 3. Trendelenburg M, Courvoisier S, Spath PJ, Moll S, Mihatsch
M, Itin P, et al. Hypocomplementemic urticarial vasculitis or
nYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC1y0abggQZXdgGj2MwlZLeI= on 03/17/2023

systemic lupus erythematosus? Am J Kidney Dis 1999; 34:

REFERENCES
1. Davis MD, Daoud MS, Kirby B, Gibson LE, Rogers RS, 3rd.
Clincopathologic correlation of hypocomplementemic and
normocomplementemic urticarial vasculitis. J Am Acad
Dermatol 1998; 38: 899–905.
745–51.
4. Chen HJ, Bloch KJ. Hypocomplementemic urticarial vasculi-
tis, Jaccoud’s arthropathy, valvular heart disease, and reversible
tracheal stenosis; a surfeit of syndromes. J Rheumatol 2001; 28:
383–6.

ANSWERS TO THE RHEUMATOLOGY QUIZ

(page 171) ***Given by intravenous infusion.
†
This is a minor criterion.
1c*, 2d**, 3a, 4d, 5b***, 6c†, 7a††, 8b†††, 9c¥, 10a¥¥ ††
Pattern of joint involvement mimics RA.
†††
*MCTD—lower oesophageal sphincter, RA and inflammatory Paraneoplastic syndrome which usually has an explosive
myopathy—both upper and lower oesophageal sphincters onset.
¥
affected. Worsened by heat.
¥¥
**18 FDG PET does not provide information about luminal Hyperelastic skin and hyperextensible large joints are not
flow or wall structure. seen in this type, also known as the vascular type.