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    Asim Dutta
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    The document discusses the affinity levels of compounds found in plants, with broadly distributed compounds having low affinity towards enzyme targets in the mM to uM range, while unique compounds have high affinities in the nM range. It also notes that natural plant products can modulate liver function and treat central nervous system disorders, with many medicines for neurodegenerative disorders derived from plants. Additionally, molecules from plants are able to enter the blood brain barrier, even large ones like Rapamycin, despite one sentence claiming no antibiotics have been discovered from plants.

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    The document discusses the affinity levels of compounds found in plants, with broadly distributed compounds having low affinity towards enzyme targets in the mM to uM range, while unique compounds have high affinities in the nM range. It also notes that natural plant products can modulate liver function and treat central nervous system disorders, with many medicines for neurodegenerative disorders derived from plants. Additionally, molecules from plants are able to enter the blood brain barrier, even large ones like Rapamycin, despite one sentence claiming no antibiotics have been discovered from plants.

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    6 views1 page

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    Uploaded by

    Asim Dutta
    The document discusses the affinity levels of compounds found in plants, with broadly distributed compounds having low affinity towards enzyme targets in the mM to uM range, while unique compounds have high affinities in the nM range. It also notes that natural plant products can modulate liver function and treat central nervous system disorders, with many medicines for neurodegenerative disorders derived from plants. Additionally, molecules from plants are able to enter the blood brain barrier, even large ones like Rapamycin, despite one sentence claiming no antibiotics have been discovered from plants.

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    Broadly distributed compounds has low affinity towarsd enzyme targets (mM to uM)

    Eg. Flavonoid having high nutraceutical value


    The unique comppunds have high affcinittes (nM). E.g. Forskolin, Artemisinin having
    high pharmaceutical value

    Invaribly all natural plant products modulates Liver function.


    Likewise all plant product has special connection with human head. Almost all
    medicine used to treat discorder of
    centralnervous system are natural plant products. This area of neurodegerative
    disorder could be a potential
    high value contribution by Ayurveda in modern medicine.

    No Antibiotics have ever been discovered from Plants.

    Only Natural molecules are allowed to entre the Blood Brain barrier even if
    moleculesasa large as Rapamycin

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