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Psychiatry Research 215 (2014) 683–686

Contents lists available at ScienceDirect

Psychiatry Research
journal homepage: www.elsevier.com/locate/psychres

Neither too much, nor too little. The dilemma of identifying personality
disorders in adolescents patients with self-reports
Ernesto Magallón-Neri a,b,n, José Eugenio De la Fuente a, Gloria Canalda a, Maria Forns b,
Raquel García a, Esther González a, Anais Lara a, Josefina Castro-Fornieles a,c,d
a
Department of Child and Adolescent Psychiatry and Psychology, SGR-1119, Institute of Neurosciences, Hospital Clinic Universitari of Barcelona,
and Biomedical Research Center in Mental Health Network CIBERSAM, Barcelona, Spain
b
Department of Personality, Assessment and Psychological Treatment, Faculty of Psychology, University of Barcelona, Spain
c
IDIBAPS (Institut d0 Investigacions Biomediques August Pi Sunyer), Barcelona, Spain
d
Department of Psychiatry and Clinical Psychobiology, Universitat de Barcelona, Spain

art ic l e i nf o a b s t r a c t

Article history: The study aimed to compare methods of identification of Personality Disorders (PD) in adolescent
Received 2 January 2013 patients with psychiatric disorders. A sample of 120 Spanish adolescents with clinical disorders was
Received in revised form assessed using the International Personality Disorder Examination (IPDE) interview, its Screening
19 August 2013
Questionnaires (IPDE-SQ) comprising the ICD-10 and DSM-IV modules, and also the Temperament
Accepted 15 December 2013
Available online 22 December 2013
Character Inventory (TCI) to identify risk of PD. The IPDE-SQ identified a risk of PD around 92–97% of the
sample; 61.7% when adjusting the stricter cut-off points. The TCI showed a PD risk of 20%, whereas the
Keywords: prevalence of PD identified by the IPDE clinical interview was around 36–38%. The differences between
Self-report the IPDE, IPDE-SQ and TCI were significant, and a low agreement among instruments was obtained. Large
Personality disorders
discrepancy between self-report instruments in identifying PD with regard to the clinical interview raises
Adolescents
several questions concerning the use of these instruments in clinical settings on adolescents with
Concordance (measurement)
Personality psychiatric disorders.
& 2013 Elsevier Ireland Ltd. All rights reserved.

1. Introduction Montalvo and Echeburúa, 2006) must be addressed in the assess-


ment of reliable profiles of personality. However, in clinical
The identification of pathological personality is a widely interviews there are more chances to elucidate between psycho-
studied field, in which increasingly sophisticated assessment pathological features associated with other Axis I disorders and
instruments are being designed (Clark, 2007). However, many of their distinguishing from those ones that could certainly be
these instruments show low levels of agreement in the identifica- considered personality pathological features (Huprich et al., 2011;
tion of the same construct and so the field is still in development Chanen et al., 2004; Fernández-Montalvo and Echeburúa, 2006).
(Egan et al., 2003; Gárriz and Gutiérrez, 2009; Krueger et al., 2011; However, these interviews require prior training, considerable
Nestadt et al., 2012; Schneider et al., 2004; Zimmerman and clinical experience and a profound understanding of psychopathol-
Coryell, 1990). In clinical practice the assessment of personality ogy (Lenzenweger, 2006; Siefert, 2010).
pathology is broadly used self-reports or screening questionnaires The appropriateness of evaluating PD in adolescents is itself
(Blasco-Fontecilla et al., 2010; Germans et al., 2012; Morse and contested, because the risk of the stigma effect and the fact
Pilkonis, 2007; Siefert, 2010). This practice saves consultation time, that in a considerable proportion of children and adolescents
but the accuracy of the assessments is sometimes insufficient these symptoms may remit over time (Bornovalova et al., 2009;
(Huprich et al., 2011; Lenzenweger, 2006; Fernández-Montalvo Freeman and Reinecke, 2007; Widiger, 2005). Assessment at an
and Echeburúa, 2006; Slade et al., 1998). early age poses its own particular problems because the frontiers
Self-reports and interviews tend to be vulnerable to manipula- of psychopathology are very diffuse, and comorbidity is frequent
tion by patients. The risk of either simulation (increasing symp- (Chanen et al., 2004; Clark, 2007; Cheng et al., 2011; Feenstra
toms) or dissimulation (minimizing symptoms) (Fernández- et al., 2011; Magallón-Neri et al., 2012; Shiner and Caspi, 2003).
Although, a great amount of empirical research ratifies the
n existence of pathological personality and personality disorders
Corresponding author at: University of Barcelona, Department of Personality
Assessment and Psychological Treatment, C/Pg. Vall d Hebron, 171-08035, Barce- in adolescence (Chanen et al., 2004; Feenstra et al., 2011; Westen
lona, Spain. Tel.: + 34 93 403 11 54; fax: + 34 934 021 362. et al., 2003).

0165-1781/$ - see front matter & 2013 Elsevier Ireland Ltd. All rights reserved.
http://dx.doi.org/10.1016/j.psychres.2013.12.020
684 E. Magallón-Neri et al. / Psychiatry Research 215 (2014) 683–686

This study aims to compare two self-report instruments, the 2.3. Procedure
International Personality Disorder Examination Screening Ques-
tionnaire (IPDE-SQ) and the Temperament Character Inventory Axis I diagnoses were made by the clinical team (psychologists and psychia-
(TCI), with a semi-structured clinical interview (IPDE) for trists) in our department in accordance with DSM-IV and ICD-10 criteria. The study
was explained in detail to parents and participants who gave written, informed
identifying overall proportions of probable personality disor- consent before entering the study, and the evaluation protocol was reviewed and
ders in a sample of adolescents treated at a public mental health approved by the hospital ethics committee. Ethics committee0 s reference
service. number: 5098.

2.4. Data analysis


2. Method
Sensitiviy (SEN), specificity (SPE), rate of False Positives (FP) and False Negatives
2.1. Participants (FN) were calculated. Frequencies, contrast of proportions for qualitative variables,
and calculation of kappa indexes were used to assess the agreement of risk
The adolescents recruited met the following criteria: age from 15 to 18 years proportions for PD between instruments. Statistical analysis of data was performed
old, referred to the Department of Child and Adolescent Psychiatry and Clinical using SPSS 16.0.
Psychology at the Hospital Clinic of Barcelona. Patients with acute psychopathology
(severe depression, or acute psychotic state) and mental retardation that might
preclude the application of the tests were excluded. A total of 184 participants met 3. Results
the inclusion criteria, though 39 refused to participate. The remaining 145 were
evaluated; 25 did not complete the assessment. This study presents the results of
the subjects (N ¼ 120) who completed both self-reports, the IPDE-SQ and the TCI, The sample consisted of 120 participants. Most participants
and the IPDE clinical interview. were female (86.7%). Age ranged between 15 and 18 years old
(mean age¼15.88, SD ¼0.90) and most patients had one or two
2.2. Instruments
Axis I diagnoses (mean ¼1.55, SD ¼0.89). The frequency of Axis I
clinical disorders are: four (3.3%) with psychotic disorders, 10
International Personality Disorder Examination (IPDE): a semi-structured (8.3%) with substance use disorders, 17 (14.2%) anxious disorders,
clinical interview for personality disorders developed by Loranger et al. (1994) 17 (14.2%) with adjustment disorders, 20 (16.7%) with externaliz-
and the World Health Organization. The interview has two modules of assessment, ing disorders, 21 (17.5%) with affective disorders, 88 (72.5%) with
based on the criteria of the International Classification of Diseases Tenth Revision eating disorders, and 15 (12.5%) patients with other Axis I
(ICD-10) with 67 semi-structured questions and the Diagnostic and Statistical
Manual of Mental Disorders, Fourth Edition (DSM-IV) with 99 semi-structured
disorders. The high percentage of patients with eating disorders;
questions. This instrument shows good psychometric properties (Loranger et al., is because the Department of Child and Adolescents Psychiatry
1997). and Clinical Psychology of the Hospital Clinic of Barcelona is a
IPDE Screening Questionnaire (IPDE-SQ): a screening instrument developed for national reference center for this type of pathology.
the detection of the risk or probability of personality disorders from the ICD-10
The risk proportions for PD between IPDE-SQ, TCI and the IPDE
(True/False; 59 items) and DSM-IV (True/False; 77 items) taxonomies. Both versions
assess a number of criteria associated with each of the PDs. The standard Spanish interview are shown in Table 1. Significant differences neither
guidelines set a cut-off score of three or more positive items for detailed revision of were found in PD proportions between sexes nor in the global
the risk of each PD using the interview IPDE (López-Ibor et al., 1996, p. 73). Initially proportion of PDs comparing those participants who had an eating
this cutoff point was considered as this study0 s baseline. Moreover, due to the disorder with regard to those who had no eating disorder. The
absence of adjusted cut-off points for adolescent population, we decided to use
another stricter cutoff points coming from Blasco-Fontecilla et al. (2010) study,
overall recorded proportions varied greatly between instruments:
which was performed with a Spanish adult clinical sample, recruited by emergency while the IPDE-SQ module ICD-10 identified a risk of PD in 91.7%
services by using the IPDE-SQ module DSM-IV. The adjusted cuttoff points for each (95%CI 0.85–0.96) with a SEN (0.98) and SPE (0.12) with a 54% of
PD were: five to Paranoid, five to Schizoid, seven to Schizotypal, five to Antisocial, FP and 1% of FN regarding to IPDE interview ICD-10 module; and
seven to Borderline, six to Histrionic, seven to Narcissistic, five to Avoidant, six to
the module DSM-IV a risk in 96.7% (95%CI 0.92–0.99) with a SEN
Dependent and six in Obssessive–Compulsive.
Temperament and Character Inventory (TCI): contains 240 items that assesses (1.00) and SPE (0.05) with a 61% of FP and 0% of FN regarding to
seven dimensions: four temperament (Novelty Seeking, Harm Avoidance, Reward IPDE interview DSM-IV module. The TCI identified a risk in only
Dependence and Persistence) and three character (Self-directedness, Cooperation 20% (95%CI 0.13–0.28), with a SEN (0.33) and SPE (0.88) with a 8%
and Self-transcendence) (Cloninger et al., 1994). This model integrates concepts of of FP and 26% of FN regarding to IPDE interview ICD-10 module
neurobiology and behavior genetics with features derived from socio-cultural
learning (Svrakic et al., 2002). Profiles with low scores (Percentile r 33) on the
and a SEN (0.33) and SPE (0.87) with a 8% of FP and 24% of FN
traits of Self-directedness and Cooperation have been studied and validated as regarding to IPDE interview DSM-IV module. Then, we applied the
indicator traits of possible PD (Cloninger et al., 1994). adjusted cutoff points proposed by Blasco-Fontecilla et al. (2010)

Table 1
Contrasted proportions of personality disorders identified by IPDE-SQ, TCI, and IPDE interview.

Instruments contrasted % PD z-score Agreement Kappa (95% CI)


n (%) Kappa

IPDE-SQ ICD-10 vs. TCI 91.7 vs. 20.0 10.11nnn 34 (28.3) 0.04 (0.01–0.07)
IPDE-SQ DSM-IV vs. TCI 96.7 vs. 20.0 11.04nnn 28 (23.3) 0.02 (0.00–0.03)
IPDE-SQ SBF vs. TCI 61.7 vs. 20.0 5.69nnn 62 (51.6) 0.15n (0.04–0.26)
IPDE-I ICD-10 vs. IPDE-SQ ICD-10 38.3 vs. 91.7  5.97nnn 54 (45.0) 0.08 (0.01–0.15)
IPDE-I ICD-10 vs. TCI 38.3 vs. 20.0 2.71nn 80 (66.7) 0.23nn (0.06–0.39)
IPDE-I DSM-IV vs. IPDE-SQ DSM-IV 35.8 vs. 96.7  6.82nnn 47 (39.2) 0.04 (0.00–0.07)
IPDE-I DSM-IV vs. TCI 35.8 vs. 20.0 2.37nn 81 (67.5) 0.22nn (0.04–0.39)
IPDE-I DSM-IV vs. IPDE-SQ SBF 35.8 vs. 61.7  2.96nn 83 (69.2) 0.42nnn (0.29–0.56)

PD ¼Personality Disorder; IPDE-I ¼ International Personality Disorder Examination Interview; IPDE-SQ ¼ IPDE Screening Questionnaire; TCI ¼Temperament Character
Inventory; CI ¼Confidence interval; SBF ¼ Using adjusted cut-off points of Blasco-Fontecilla et al. (2010) study for IPDE-SQ DSM-IV criteria.
n
po 0.050.
nn
p o0.010.
nnn
p o0.001.
E. Magallón-Neri et al. / Psychiatry Research 215 (2014) 683–686 685

used in adult clinical patients for the DSM-IV module of the IPDE- There are a lot of possible reasons for these discrepancies:
SQ, finding that 61.7% (95%CI 0.52–0.70), with a SEN (0.93) and SPE among these ones there are: the nature of the instruments, their
(0.55) with a 28% of FP and 3% of FN regarding to IPDE interview structural design and the developmental issues of age that have a
DSM-IV module. On the other hand, the IPDE interview found an relative importance. Teenagers with clinical disturbances may be
overall prevalence of PD of 38.3% (95%CI 0.30–0.48) with the ICD- have difficulty reaching the level of abstraction or implication
10 module and 35.8% (95%CI 0.27–0.45) with the DSM-IV module. required to understand the questions, or may confuse Axis I
In both screening instruments IPDE-SQ (ICD-10 and DSM-IV), the psychopathology with their own personality traits (Feenstra
sensitivity was high with low specificity. In contrast, in the TCI it is et al., 2011). Equally, they may lack the necessary insight or have
presented high specificity and low sensitivity related to the IPDE difficulties in differentiating between what they think about
interview. When the screening test for DSM-IV module was themselves and the image they feel they have to project.
adjusted, the high sensitivity was maintained and specificity The possible effect of simulation/dissimulation in adolescents
increased, indicating the best option, but the false positive rate (such as in adult populations) appears to be an attempt to project
was relatively high. The rates of PD among IPDE interview, IPDE- an image with others rather than an attempt to distort the results.
SQ and TCI showed a poor-moderate agreement (23–69%) and Given these inconsistencies, the clinician should consider in-depth
concordance (mean kappa between 0.02 and 0.42). clinical assessment (applying a clinical interview such as the IPDE),
taking into account essential features such as frequency, duration,
stability and degree of involvement of the symptoms.
We advocate adjusting the IPDE-SQ cut-off points, especially in
4. Discussion clinical patients (Slade et al., 1998). In our group, we adjusted the
cutoff points in the case of Borderline and Impulsive PDs for
This study found strong inconsistencies in assessing PDs using adolescents (Magallón-Neri et al., 2013), but it is necessary to
different methods of evaluation. Our findings add to the debate on extend the research to all PDs taking into account the character-
the exclusive use of self-reports for assessing PDs (Huprich et al., istics of personality disorders in adolescence (Shiner and Caspi,
2011), and highlight concerns already voiced in previous studies 2003).
(Egan et al., 2003; Fernández-Montalvo and Echeburúa, 2006;
Nestadt et al., 2012; Zimmerman and Coryell, 1990).
The large discrepancy found between the IPDE-SQ and the TCI
regard to IPDE interview in this study may be due to differential 4.1. Strengths and limitations
structural aspects. While the IPDE-SQ expresses the DSM-IV and
ICD-10 criteria of each PD categorically with a speed screen The main strength of the study is the identification of the risk
(Blasco-Fontecilla et al., 2010; Lenzenweger, 2006) the TCI focuses of PD in a clinical sample of adolescents, comparing the individual
on a dimensional assessment of temperament traits and character performance of two modules of the IPDE-SQ (ICD-10 and DSM-IV),
(Cloninger et al., 1994). On the other hand, the clinical interview with the TCI, and comparing their agreement with a gold standard
IPDE gives the possibility to investigate further, and to make a (IPDE).
differential diagnosis based on information obtained from the The study has two main limitations that should be borne in
patient getting closer to complex nature of the personality mind in the interpretation of the results. The first is that women
pathological features, and not just simply report on the existence with eating disorders were overrepresented in the sample; though
of clinical symptoms, that patient may confuse and that in turn no significant differences were found between sexes, this pre-
may confuse the patient with some other type of comorbid dominance of women may have introduced a bias. Second, the
psychiatric manifestations (Huprich et al., 2011; Loranger et al., screening instruments were applied cross-sectionally, with the
1997). result that we are unable to observe associations of direction, of
The identification rate for PD with the IPDE-SQ were higher where pointing the trend of risk to suffer PD in this clinical
than those identified by this instrument in the adult population teenager sample.
(Blasco-Fontecilla et al., 2010; Cheng et al., 2011; Huang et al.,
2009) and twice than identified in adolescent studies based on
structured interviews (Chanen et al., 2004; Feenstra et al., 2011;
Magallón-Neri et al., 2012); the prevalence of PD with the TCI was 4.2. Conclusions
around half that identified with a more detailed exploration based
on clinical interviews. These significant differences are less clear if The large discrepancy between the IPDE-SQ instruments and
we look at other cut-off points (Blasco-Fontecilla et al., 2010) or if TCI in identifying personality disorders with regard to the clinical
we consider a broader subset of people with probable PD, rather interview IPDE raises several questions concerning the use of
than those who only had clear evidence of the disorder. In either of these instruments in adolescents with psychiatric disorders. First,
these nuanced situations, we are making an estimation of the risk clinicians should consider the need to use different psychological
of probable PD, not a formal diagnosis. Even increasing the cut-offs techniques and instruments to verify the discrepancies in the
as Blasco-Fontecilla et al. (2010) suggested, many subjects remain identification of pathological personality features in adolescents.
over-identified. Second, the use of clinical interviews allows refining the para-
Regard to the TCI, perhaps the comparision with the IPDE meters of problem behavior under study (Frequency, Intensity,
screening instruments and their clinical interview, were not the Number, Duration and Sense) allowing a deep analysis of sympto-
most appropriate, and perhaps there should have been more matology, aspect not covered in detail in most of self-report
desirable comparisions with other instruments that would have measures. Third, the screening are useful from the point of view
similar features such as PDQ-4 utilized in studies of Cheng et al. of saving clinical attention time but its use requires later an extra
(2011) or even Million (MCMI-II; Marañón et al., 2007). However, exercise to precise and clarify those cases rated as positive,
comparision with this type of instruments in that “apparently” verifying with the patient the discrepancies between techniques.
saves more power comparision, because each of them identify For these reasons, a more thorough psychiatric assessment is
specific PDs and not only pathological personality traits, the level needed before personality disorder can be confirmed in clinical
of agreement found was moderately low (Marañón et al., 2007). adolescent population.
686 E. Magallón-Neri et al. / Psychiatry Research 215 (2014) 683–686

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