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DNA Handout Replication Model Folding Activity
DNA Handout Replication Model Folding Activity
DNA Handout Replication Model Folding Activity
BACKGROUND INFORMATION:
A cell’s genetic material (DNA) must be replicated or copied in anticipation of cell division. The new
cells that form after cell divide must be completely alike and have exactly the same amount of DNA to
function normally.
The process of DNA replication has three steps: 1) the DNA molecule unzips; 2) new nucleotides
are added to each side of the original DNA molecule; and 3) enzymes zip up and complete the two DNA
molecules.
PRE-ACTIVITY QUESTIONS:
1. What organic compound grouping does DNA belong to?
4. What are the four nitrogen bases in DNA and how do they pair with each other?
5. What type of chemical bond holds the two strands of DNA together?
7. What does it mean when it is said that all living organisms have a universal genetic code?
8. Explain what is meant by if there are only 4 nucleotide types in DNA, why are all living things so
different?
11. Why is it important that an exact copy of the original DNA is made before cell division (EX: if your
body makes new skin cells or new blood cells)?
2. Complete the activity steps for modeling DNA REPLICATION found on page 3 on this handout.
3. In the chart below show the results of what happened to the original DNA model when it underwent
replication. List the nitrogenous bases on the lines. How do the strands compare? _______________
KEY:
T= 1. Fold a flap to the
A= back of the page
along this line.
C=
G=
S= 2. Follow your
teacher’s model
P= and
ORIGINAL DNA fold page in half
STRAND on this line.
6. Compare/contrast the original DNA molecule (old strands) with the 2 new DNA
molecules created by the replication process. How is this unlike making a photocopy of
the original DNA molecule?