ROMEL CRUZ HOSPITAL (DRUG STUDY 1)

Generic Name  Dosage and  Indications  Contraindications  Mechanism of Side Effects  Nursing
Action Responsibilities
Norepinephrine Frequency 

Brand Name  Patient’s • Produces • Patients with Is a • When

Dosage & vasoconstriction and hypotension but is sympathomimeti administering the
• Blinor  Excessive
Frequency:  myocardial likely secondary c amine derived medication, follow
vasoconstriction
stimulation, which cardiogenic and from tyrosine it is the 10 RIGHTs.
Classification  • IV 4mg/4ml Increased pulmonary
may require after related to structurally
vascular resistance • Evaluate vital
adequate fluid. hypervolemia identical to
• Alpha/Beta increased systemic signs and
epinephrine but it
adrenergic Used for blood vascular resistance appropriately
lacks methyl
agonist pressure control in and will decrease record them
group in its
specific acute hepatic flow especially the
nitrogen atom.
hypotensive states blood pressure.
The increased
and treatment for
activation to the determine whether
cardiac arrest with
alpha 1 receptors the client has a
profound
can result to history of drug
hypotension.
vasoconstriction. allergies.
• Watch out for
negative effects
. • Record the
administration of
the medication to
Generic Dosage and Indications  Contraindications  Mechanism of Side Effects  Nursing
Name  Frequency  Action Responsibilities
Tolvaptan

Brand Name  Patient’s • Treatment of • Tolvaptan is  Blurred Verify the doctor's

Dosage & symptomatic and contraindicated in Tolvaptan is a vision. order to prevent
•
Frequency:  resistant to fluid patients unable to sense selective and errors.
 flushed,
restriction or respond to thirst; competitive arginine
Classification  • 30 mg OD dry skin. When
euvolemic or such patients are at vasopressin receptor
administering the
hypervolemic increased risk of 2 antagonist.  frequent
• Vasopressin medication, follow
hyponatremia incurring an overly Vasopressin acts on urination.
antagonist the 10 RIGHTs.
associated with rapid correction of the V2 receptors
congestive heart serum sodium, found in the walls of  fruit-like
Evaluate vital
failure, SIADH, hypernatremia, and the vasculature and breath
signs and
and cirrhosis. hypovolemia. luminal membranes odor.
appropriately
of renal collecting  increased record them. To
ducts. By blocking hunger. prevent difficulties,
V2 receptors in the determine whether
renal collecting  increased the client has a
ducts, aquaporins do thirst. history of drug
not insert themselves allergies.
 increased
into the walls thus
urination. •Watch out for
preventing water
absorption. This  increased negative effects.
action ultimately volume of Record the
results in an increase pale, administration of
in urine volume, dilute the medication to
decrease urine urine.
osmolality, and frequently monitor
increase electrolyte- patients for
free water clearance changes in serum
to reduce electrolytes,
intravascular volume volume status, and
and an increase serum neurologic status.
sodium level.
When tolvaptan
Tolvaptan is especially
treatment is
useful for heart failure
discontinued, teach
patients as they have
patients to resume
higher serum levels of
fluid restriction as
vasopressin.
directed by the
healthcare provider.
Encourage patients
• Terminate or discontinue  infusion if uterine  

hypersensitivity occurs.