35) ---------- have 6-10 days duration of action and ----------- have 6 hours

A: Atropine, Scopolamine
B: Scopolamine, tropicamide
E: Atropine, tropicamide

38) All of the following are symptoms of ganglion blocking except

A: Anhidrosis and xerostomia
B: Mydriasis
C: Tachycardia
D: Hypertension
E: Cycloplegia

9. Succinylcholine is similar to rocuronium with regard to

Succinylcholine is similar to with regard to duration of action.
a. organ independent elimination; cis atracurium
b. onset time; no other agent
c. side effect profile; mivacurium
d. side effect profile; pancuronium

10. Which of the following drugs can be used to reduce intraocular pressure in
the treatment of glaucoma?
a. Pilocarpine
b. Acetazolamide
c. Neostigmine
d. Timolol
e. All of the above

11. Edrophonium inhibits acetycholinesterase by forming ….. , whereas

neostigmine and pyridostigmine inhibit acetylcholintesterase by
forming….
a. an electrostatic attachment to the anionic site on
acetycholinesterase; a carbamyl-ester complex at the esteratic site
on acetylcholinesterase
b. a carbamyl-ester complex at the esteratic site on
acetylcholinesterase; an electrostatic attachment to the anionic site
on acetycholinesterase
c. a true, covalent bond with acetylcholinesterase; a hydrogen bond
with acetylcholinesterase
d. an irreversible phosphorylated complex at the esteratic site on
acetylcholinesterase; a carbamyl-ester complex at the esteratic site
on acetylcholinesterase

55. Which of the following reversible cholinesterase inhibitors is used for

atropine intoxication?
A. Neostigmine
B. Physostigmine
C. Endrophonium
D. Donepezil
E. Pyridostigmine

27. Non-depolarizing neuromuscular blockers:

Bind at the site and prevent Ach from binding

Butyrylcholinesterase (BuChE) is a nonspecific pseudocholinesterase located in

glia, plasma, liver, and other organs. What type of local anesthetics are
metabolized by BuChE (e.g. procaine), along with succinylcholine (paralytic)?
a) Ester
b) Ether
c) Amine
d) Alkane
e) Alcohol

29. cholinesterase activity have the potential to :

Decrease hydrolysis of ester-type local anaesthetics

33. Wrong answer regarding depolarizing NM blockers:

At low dose the activate nicotinic receptor causing fasciculation.

34. Wrong answer regarding isoproteronol:

Don't affect CO

1- Succinylcholine is like rivacurium in ----time of onset---------- , and is like

-----------no other agent------ in duration of action.
22.Antidote for anticholinergic agent:
 -Physostigmine

16) Beta blockers which may be less likely to produce CNS-related adverse effects
include
A. metoprolol
B. nadolol
C. timolol
D. atenolol
1. A,B,C
2. A,C cardioselective (B1)
3. B,D
4. D only
17) Clonidine hydrochloride lowers blood pressure by reducing sympathetic tone.
It is believed to act by inhibiting sympathetic outflow from the vasomotor center
in the medulla. A potentially serious adverse reaction that has been reported is:
A: ventricular fibrillation
B: anaphylaxis
C: irreversible nephrotoxicity
D: withdrawal syndrome resembling hypertensive crisis
E: systemic lupus erythematosus
43) Which of the following is a Betta blocker with alpha antagonist activity?
A: Carvedilol
B: labetalol
C: Nebivolol
D: Atenolol

50) Choose correct answer, β agonists:

A: bind to post synaptic adrenergic receptors

51) What is wrong?

B: Phenylephrine is α1 and α2 antagonist ( α1 agonist )

Primary mechanism of ephedrine (orally administered) cardiovascular action:

a. direct alpha receptor agonist
b. direct beta-1 receptor agonist
c. release of stored catecholamines (indirect action)
d. ephedrine not active following oral administration
e. release of stored histamine (indirect action)

25. Properties of ephedrine:

a. orally active
b catecholamine
c. weak base
d. A & C
e. A, B & C

56. You are given a list of drugs to and you should know if alpha or betta
agonist/ antagonist
phenylephrine α1 agonist
isoproterenol B1 B2 agonist
yohimbine α1 antagonist

A 35 yr. old, overweight female purchased a weight-reduction product which

contained ephedrine. She is using the product in accordance with directions on
the label for one-month, then stopped using it during a vacation week, and then
started again upon her return to work. Two days after restarting, she was
awakened by anterior chest pain, which radiated to her left shoulder and arm.
She experienced numbness in the left arm, shortness of breath, and sweating
(diaphoresis). At the emergency department, she was treated with morphine and
nitroglycerin. Cardiac catherization revealed 60% narrowing of the left anterior
descending coronary vessel and a 50 percent narrowing of the circumflex
coronary artery. There was no evidence of completely occluded coronary vessels.
ECG tracings indicated T-wave changes indicative of an acute myocardial
infarction, later confirmed by elevated cardiac enzymes. Recovery was
uneventful; the patient was discharged with instructions to avoid using the weight
loss product or similar weight loss products in the future
24.Primary mechanism of ephedrine (orally administered) cardiovascular action:
a. direct alpha receptor agonist
b. direct beta-1 receptor agonist
c. release of stored catecholamines (indirect action)
d. ephedrine not active following oral administration
e. release of stored histamine (indirect action)

25. Properties of ephedrine:

a. orally active
b catecholamine
c. weak base
d. A & C
e. A, B & C
26. Possible explanations why ephedrine might cause myocardial infarction:
a. ephedrine may increase myocardial oxygen requirements
b. promotes coronary vasospasm
c. both
d. neither

27. In this patient, if it were concluded that coronary vasospasm was responsible
for acute myocardial infarction, what drugs might reduce the likelihood of a
recurrence.
a. propranolol
b. metoprolol
c. diltiazem
d. ergonovine
e. all the above

28. For what reason(s) was/were morphine used in the management of this
patient*
a. pain relief
b. bradycardic effects
c. increases cardiac output

29.What is the major rationale for administration of nitroglycerin to this

patient?
a. decrease myocardial oxygen demand
b. increase blood pressure
c. must be administered following morphine

30.What physiological factors might contraindicate the use of nitroglycerin in a

patient with acute myocardial infarction?
a. low systolic arterial pressure (< 100 mm Hg)
b. clinical suspicion of right ventricular infarction
c. both
d. neither

31. In this patient, if acute myocardial infarction was caused by ephedrine

induced increased myocardial oxygen demand and if nitroglycerin were unable to
reverse this effect, what alternative drug(s) might be effective?
a. alpha adrenergic blocker
b. beta-adrenergic blocker
c. both
d. neither
 1- Clonidine (a lot mentioned in the exam) is responsible of:
-Nephrotoxicity
-withdrawal syndrome
Its used to treat withdrawal symptoms! (added note : clonidine can be used to
minimize the symptoms that accompany withdrawal from opiates, tobacco
smoking, and benzodiazepines)
it causes Rebound HTN upon withdrawal

11-Epi and NE all except:

- Metabolized to Homovanillic acid

21-Phenylephrine and epi:

alfa agonist not antagonist

10. Drug that causes arrhythmia and hypotension except: 

 -Phenylephrine

41. Which beta blocker doesn’t penetrate the CNS:

⁃ metoprolol
⁃ Atenolol