Professional Documents
Culture Documents
Clozapina
Clozapina
"#$#%&' ()#*&' %+
! " # $
% " # $
& " # $
'
( " # $
) * "
- .
" # $ ""
+ ,
" # $ -
$/#0 , %#& # + %+ &' + &++& %+ "
+ ,
. " / "
/
3) &%+ '& + & #& $ % ' 0& #%& 4&' 5 & ')+& %+ % $ & # $/ ,, ++)# &%&'# #
" ' &% ) & #%+ *&''# '& #6 &' ,#% "# #%"#*#")& + * %+)&'# &'+ &0# %#
'& &+#$/ 6 #% $& $ %+ & # + 11 #% $ '#$&0# %# &*#6 $ %
$ % ) %0 + %0#&' %+ ,&+&'#- 3 ' #%+ )0# % " ' + &++& %+ $ % ' 0& #%&
4&' 5 % $ & # $/ $ %+#%)# & ++ # & )'+ # # &%&'# # " ' &% ) )%
# " "# 7 ++# &% -
0 (
- 3 3
+#'
#' & &'#+#$ ,
&'+ # "#$#%&'# $&) &
& &%)' $#+ #
" &%+# #$ +#$# &" &0# % ')% &+& +
,
" # $ "
$ % $ %0&
/ " "
" "
+ " ,
' 0& #%& 4&' )8 ) &+& ' '& $ %+& " # ' 1)'# 1#&%$/# /& " ++ # )'+&+# % &'#
&
" &(330
&
%3330 5 + & %+ # +&%+ $/ # & " '' #%#0# " '
+ &++& %+ # ++ % & &&-
• /&%&'# # " ' &% ) 3 / " "
# $
• )%& *# #+& "#$&
• +4 5,
"
" -
•
%0 (
• 1
• + ,
•
•
" # $ 2 -
6
/ 7
/ " " # $ )'+ # # &%&'# # " '
&% ) )% # " "# 7 ++# &%
# &%#, +&% #%+ # # #'# & () ''# " '' #%,') %0&6 $ , 11 6 &' "# '& &'+ # %# "#
)% #%, 0# % 6 " * $ %+&++& #' #9 + #1#' #' "#$ 1
/
" # $ 2 + ,
" # $ 2 " + ,
"
+ , " # $
. " / "
/ " / "
-
•
• / " " /
+ 8' 9,
-
•
•
•
• :
; 8* " " # $ 9
7 " # $ 2 &6<
& -
*
1 #%"
% ) ' ++#$& &'# %& / 2
-
• 1
• "
•
• "
• "
&0 (
• " "
% ' $& # &%#, +# , 11 5# +&%+ $/ #%, # #' "#$
. " "
+ , + ,
> -
• "
• "
•
• " "" 1 " ?
? /
" # $
1 ""
. " 1 /4 5 + / >,-
/
> 1 "
. " 2 / "
2 :
"
" # $ " 0 @
-
• "#$#%&'# % +# # '& ,)%0# % " ' #" '' -
" /
$ "
'0 (
" + , "
"
" " ./
• 1 %0 "#&0 #% 1 0
@ / " # $
" / " " 2
0
• &'$)%# "#$#%&'# ) &+# #' + &++& %+ " '' &'' # ./
2
• "#$#%&'# % +# * $& "# +) 1# $& "#&$# + / >, -
+ ,
./
• &%+#$ '#% #$# / "
*
" # $ 2 /
• "#$#%&'# &++# & #") '& # % &% )# %&
" # $ 2
" "
• :#%#1#+ # "#$#%&'# $/
/&%% ,, ++# )' # + &% * $ %+ &' + ""
, " " " # $
" # $ 2 "
-
• ;& ,& #%
• "# #%& /
(0 (
. " " # $ 2
" - " # $
" # $ - "
1 1
&*#"&%0& &''&++& %+
%, &0# %# # +&%+# ) &'$)%# $$# # %+# "# ' 0& #%& 4&'
<- 3
& + & #& " * ) *# # %&+& "& )% $#&'# +& + % ' + &++& %+ "#
#$ # $/#0 , %#$/ -
" # $ "
)0 (
&) %+& &")&' %+
% + %( (3 " ,
&33 E / %&
* " ? 2
%' + (3 33 " ,
• %0#&%#
" " ? -I + %(
" ,
+%( " ,
• ?& 1#%#
. "" / " 1 )
" # $ ) 1
? "
E 1
J0 (
I + %( " ,
% +(3
" , 2 .
. % +(3 " ,
" ' + 33 " ,
5 +
" " " , "
%
" "
: " # $ 2
I + %( , & # "# 7
$ + 33 ,
" ")
1 " # $ ""
/ " # $ 2
" " # $ =
"
" 1
" "
"
"
60 (
+ " ,
""
+ ,
"
0
"
"
"
"
) 1 "
"
- " # $
"
" # $ ?
" # $ ? "
2 "
7- ? 3 3
7 / " # $ " -
+
6
)% # " "# 7 ++# &% " ' #%+ )0# % " ,#%#+#*& " ''& + & #& $ % ' 0& #%&
4&', C #%+ # #%,') %0&'# &' "# '&
, 11 # &''#"# %+ & # $)+&%
?
" # $ ? "
# $
K0 (
" # $ 2
. " " -
+ 3 " ,
+ 33 " 3,
+ 333 " 33,
+ 3 333 " 333,
+ 3 333 " ,
+ ,
+ ,
" " + ,
+
,
/
" =
"
+ ,
" + ,
" "
+ ,
" "
" " / 1
" + ,
" "
"
"
"
3# +) 1# #$/#&+ #$#
30 (
""
"
" 0 "
"
""
1 "
0 0
"" + ,
" + ,
"
" + ,
"
" + 0 ,
" + ,
+ ,
+ / > ,
" + " ,
+ ,
"
" +
,
1
0 (
&+ ' # # &+ # 6 + &$#$/ "#& +#%#$/
"
/
""
"
"
" + ,
@
"
/
"
"
&+ ' # " ' # + & ) $ ' $/ ' + #$ " '+ )+ $ %% ++#*
" + ,
"
%0 (
"
" "
/ "
1 " " "
" + ,
?
+
,
>
" "
/
"" ? 1 /
A-
5
+L%(, + *,
3 $ #0# % " '' & ++ "# ' 0& #%& 4&' $ %+ %)+ " ''& $ %, 0# %
. " # $ . %(
" "" 1
8 %(9
. 33
&0 (
. " # $ "
1 - %3 %6 &3 '3 (3 )3 + " # $ 33 ,
6' K6 33 3 $ (3 33 $ (3
M " ""
#4G*. *
. A N
% 3'3 D +;*,
")++ #
5 # D ; 5 : * &K JK N 5
#4G*. *0 L 6 % %)(3 # 7
B) + " ++ "#$#%&' 5 +&+ &)+ #00&+ % '# +&+# 1 # " '' &0# $ % #$ )
$ %' ) %+# " % #%&0# %#
*
.DF* 8#4G*.9 %( >
.DF* 8#4G*.9 (3 >
.DF* 8#4G*.9 33 >
N
" " %(
" " (3
" " 33
C
" " %( O
" " (3 O
" " 33 O
4
" " %(
" " (3
" " 33
5
" " %( >
" " (3 >
" " 33 >
7
" #4G*.
'0 (
H
" #4G*.
5
" 0 "
A
" " %(
" " (3
" " 33
" $ %( >
" $ (3 >
" $ 33 >
.DF* * #4G*. %(
.DF* * #4G*. 33
.
" " %(
" " (3
" " 33
.
" " 33 P
D
" " %( %(
" " (3 (3
" " 33 33
" #4G*.
" $ %(
" $ (3
" $ 33
B) + , '# #'') + &+#* 5 +&+ & *&+ ' )'+# & * '+& % ' ++ 1 ! !
(0 (